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Kenneth C. Anderson, MD
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Journal Articles

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Anil Aktas Samur, PhD, Tessa Han, Marco Roncador, MD MSc, Mariateresa Fulciniti, PhD, Raphael Szalat, Masood A. Shammas, PhD, Jill Corre, PharmD, PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Anjan Thakurta, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3055.
DOI: https://doi.org/10.1182/blood-2019-128521
Published: 2019
Journal Articles

Lack of Significant Differences in Somatic Alterations between MGUS, SMM and Symptomatic Multiple Myeloma: A Result from Comprehensive Genomic Profiling Study

Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Raphael Szalat, Jill Corre, PharmD, PhD, Niccolo Bolli, MD PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Hervé Avet-Loiseau, MD PhD, Mehmet Kemal Samur, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3089.
DOI: https://doi.org/10.1182/blood-2019-128570
Published: 2019
Journal Articles

Defining the Differentiation States of Multiple Myeloma at Single Cell Resolution Reveals Opportunities for Immunotherapy

Julia Frede, PhD MPhil, Praveen Anand, PhD, Andrew J. Yee, MD, Tushara Vijaykumar, Monica S. Nair, Johannes M. Waldschmidt, MD, Sayalee V. Potdar, Jake A. Kloeber, Antonis Kokkalis, PhD MSc, Guangwu Guo, PhD, Samantha J. Shapiro, Mason L. Mann, Robb S Friedman, MD, Brea C. Lipe, MD, Erica L. Campagnaro, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Thomas Guerrero, MD, Omar Nadeem, MD, Jacob P. Laubach, MD, Nikhil C. Munshi, MD, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Noopur Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3091.
DOI: https://doi.org/10.1182/blood-2019-130247
Published: 2019
Journal Articles

A Phase II Study of Elotuzumab in Combination with Pomalidomide, Bortezomib, and Dexamethasone in Relapsed and Refractory Multiple Myeloma

Andrew J. Yee, MD, Jacob P. Laubach, MD, Erica L. Campagnaro, MD, Brea C. Lipe, MD, Omar Nadeem, MD, Robb S Friedman, MD, Craig E. Cole, MD, Elizabeth K. O'Donnell, MD, Giada Bianchi, MD, Andrew R. Branagan, MD, Samantha J. Shapiro, Cynthia C. Harrington, NP, Jill N. Burke, NP, Marilyn T. Gammon, RN, Kathleen J. Lively, RN, Cassandra A. Thorburn, Mason L. Mann, Jens G. Lohr, MD PhD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Noopur S. Raje, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3169.
DOI: https://doi.org/10.1182/blood-2019-124870
Published: 2019
Journal Articles

Novel Therapeutic Rationale for Targeting HDAC1 and PIM2 in Multiple Myeloma

Takeshi Harada, MD PhD, Asuka Oda, Hiroto Ohguchi, MD PhD, Yohann Grondin, PhD, Hirofumi Tenshin, DDS, PhD, Masahiro Hiasa, DDS, PhD, Jumpei Teramachi, Masahiro Oura, MD, Kimiko Sogabe, MD, Shiro Fujii, MD PhD, Shingen Nakamura, MD PhD, Hirokazu Miki, MD PhD, Kumiko Kagawa, MD PhD, Shuji Ozaki, MD PhD, Teru Hideshima, MD PhD, Kenneth C. Anderson, MD, Masahiro Abe, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3111.
DOI: https://doi.org/10.1182/blood-2019-127679
Published: 2019
Journal Articles

Results from Phase 1/2 Trial of Tagraxofusp in Combination with Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Paul G. Richardson, MD, Myo Htut, MD, Cristina Gasparetto, MD, Jeffrey A. Zonder, Thomas G. Martin, III, MD, Janice Chen, PhD, Christopher Brooks, PhD, Peter McDonald, Nicole Rupprecht, Halyna Wysowskyj, Dharminder Chauhan, PhD, Arghya Ray, PhD, Kenneth C. Anderson, MD, Claudia E. Paba-Prada, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3145.
DOI: https://doi.org/10.1182/blood-2019-130410
Published: 2019
Journal Articles

High-Dimensional Heterogeneity of Waldenström Macroglobulinemia within Its Immune Tumor Microenvironment

Jana Jakubikova, PhD, Danka Cholujova, PhD, Gabor Beke, PhD, Zachary R Hunter, PhD, Teru Hideshima, MD PhD, Ludmila Flores, Merav Leiba, MD, Paul G. Richardson, MD, Eftathios Kastritis, David M. Dorfman, MD PhD, Steven P Treon, MD PhD FRCP, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3975.
DOI: https://doi.org/10.1182/blood-2019-130011
Published: 2019
Journal Articles

Loss-of-Function of Gabarap Impairs Bortezomib-Induced Anti-Tumor Immunity in Multiple Myeloma: Clinical Application

Annamaria Gulla, MD, Eugenio Morelli, MD, Mehmet Kemal Samur, PhD, Teru Hideshima, MD PhD, Giada Bianchi, MD, Mariateresa Fulciniti, PhD, Rao Prabhala, Srikanth Talluri, PhD, Yu-Tzu Tai, PhD, Dharminder Chauhan, PhD, Ruben D. Carrasco, MD PhD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 134.
DOI: https://doi.org/10.1182/blood-2019-127845
Published: 2019
Journal Articles

Determining Resistance Mechanisms in BRAF- mutated Multiple Myeloma

Johannes M. Waldschmidt, MD, Jake A. Kloeber, Tushara Vijaykumar, Antonis Kokkalis, PhD MSc, Praveen Anand, PhD, Sayalee Potdar, Julia Frede, PhD MPhil, Monica S. Nair, Valeriya Dimitrova, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Andrew J. Yee, MD, Noopur S. Raje, MD, Birgit Knoechel, MD PhD, Jens G. Lohr, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 316.
DOI: https://doi.org/10.1182/blood-2019-130313
Published: 2019
Journal Articles

AMG 701 Potently Induces Anti-Multiple Myeloma (MM) Functions of T Cells and IMiDs Further Enhance Its Efficacy to Prevent MM Relapse In Vivo

Shih-Feng Cho, MD PhD, Liang Lin, PhD, Lijie Xing, MD, Kenneth Wen, Tengteng Yu, MD PhD, Phillip A Hsieh, Yuyin Li, PhD, Nikhil C. Munshi, MD, Joachim Wahl, PhD, Katja Matthes, Kenneth C. Anderson, MD, Tara Chapman-Arvedson, Yu-Tzu Tai, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 135.
DOI: https://doi.org/10.1182/blood-2019-128528
Published: 2019
Journal Articles

Targeting Myeloma Cell Metabolism Via Disruption of the Lnc-17-92 Transcriptional Program: Druggable New Vulnerability in Multiple Myeloma

Eugenio Morelli, MD, Mariateresa Fulciniti, PhD, Mehmet Kemal Samur, PhD, Caroline Ribeiro, PhD, Leon Wert-Lamas, PhD, Annamaria Gulla, MD, Anil Aktas Samur, PhD, Cinzia Federico, PhD, Francesca Scionti, PhD, Yao Yao, PhD, Nicola Amodio, PhD, Giada Bianchi, MD, Yu-Tzu Tai, PhD, Pierfrancesco Tassone, MD, Kenneth C. Anderson, MD, Carl D. Novina, MD PhD, Massimo Loda, MD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 317.
DOI: https://doi.org/10.1182/blood-2019-130730
Published: 2019
Journal Articles

Expanded Meta-Analyses Confirms the Association between MRD and Long-Term Survival Outcomes in Multiple Myeloma (MM)

Nikhil C. Munshi, MD, Herve Avet-Loiseau, MD PhD, Kenneth C. Anderson, MD, Paola Neri, MD PhD, Bruno Paiva, PhD, Mehmet Samur, PhD, Meletios A. Dimopoulos, MD, Margarita Kulakova, Bart Heeg, PhD, Mahmoud Hashim, Jon Ukropec, PhD, Kevin Liu, Maria Krevvata, PhD, Annette Lam, Sarah Cote, Nizar Bahlis, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4742.
DOI: https://doi.org/10.1182/blood-2019-124191
Published: 2019
Journal Articles

The Transmembrane Receptor Roundabout 1 (ROBO1) Is Necessary for Multiple Myeloma Proliferation and Homing to the Bone Marrow Niche

Giada Bianchi, MD, Peter G. Czarnecki, MD, Matthew Ho, PhD, Aldo M. Roccaro, MD PhD, Antonio Sacco, RN, Yawara Kawano, MD PhD, Anil Aktas Samur, PhD, Annamaria Gulla, MD, Tianzeng Chen, Kenneth Wen, Xinchen Wu, Yu-Tzu Tai, PhD, Gulden Camci-Unal, PhD, Irene M. Ghobrial, MD, Ruben D. Carrasco, MD PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 507.
DOI: https://doi.org/10.1182/blood-2019-128778
Published: 2019
Journal Articles

Timing the Initiation of Multiple Myeloma

Francesco Maura, MD, Even H Rustad, MD, Niccolò Bolli, MD PhD, Venkata Yellapantula, PhD, Daniel A. Leongamornlert, PhD, Ferran Nadeu, BSc, MSc, Nicos Angelopoulos, PhD, Kevin J Dawson, Thomas J Mitchell, Rob Osborne, Bachisio Ziccheddu, PhD, Cristiana Carniti, PhD, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, MD, Philippe Moreau, MD, Elli Papaemmanuil, PhD, Ludmil Alexandrov, Xose S Puente, Elias Campo, Reiner Siebert, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD, Peter J Campbell, Ola Landgren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 573.
DOI: https://doi.org/10.1182/blood-2019-124357
Published: 2019
Journal Articles

Interaction of Plasmacytoid Dendritic Cells and Myeloma Cells Trigger Tumor Promoting Transcriptional Changes in Multiple Myeloma Cells

Arghya Ray, PhD, Leutz Buon, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 510.
DOI: https://doi.org/10.1182/blood-2019-123333
Published: 2019
Journal Articles

Phase II Trial of the Combination of Ixazomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma

Mark Bustoros, MD, Omar Nadeem, MD, Adam S Sperling, MD PhD, Giada Bianchi, MD, Lily Ardente, BS, Robert A. Redd, MS, Julia Prescott, NP, Erin Frey, RN, Kathleen Guimond, RN, Rachel Styles, BS, Kalvis Hornburg, BA, Alexandra Savell, BS, Nang Kham Su, BA, Govind Bindra, BA, Cody J Boehner, BS, Kaitlen Reyes, DNP, Houry Leblebjian, PharmD, Diane Warren, Nikhil C. Munshi, MD, Jacob P. Laubach, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 580.
DOI: https://doi.org/10.1182/blood-2019-128519
Published: 2019
Journal Articles

Preclinical Validation of Alpha-Enolase (ENO1) As a Novel Immunometabolic Target in Multiple Myeloma

Arghya Ray, PhD, Yan Song, PhD, Dharminder Chauhan, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 856.
DOI: https://doi.org/10.1182/blood-2019-123328
Published: 2019
Journal Articles

Recurrent Non-Coding Mutations in BCL7A May Have Significant Functional Consequence in Multiple Myeloma

Chandraditya Chakraborty, PhD, Eugenio Morelli, MD, María Linares, PhD, Kenneth C. Anderson, MD, Mehmet Kemal Samur, PhD, Mariateresa Fulciniti, PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 857.
DOI: https://doi.org/10.1182/blood-2019-129155
Published: 2019
Journal Articles

A Phase II Study of Daratumumab in Patients with High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma: First Report of Efficacy and Safety

Omar Nadeem, MD, Robert Redd, Laura V. Stampleman, Jeffrey V. Matous, MD, Andrew J. Yee, MD, Jeffrey A. Zonder, Andrew Kin, MD, Jacalyn Rosenblatt, MD, Mark Bustoros, MD, Julia Prescott, MSN,NP, Alexandra Savell, BS, Kathleen Guimond, RN, Erin Frey, RN, Rachel Styles, BS, Adrienne Bielawski, Cody J Boehner, BS, Nang Kham Su, BA, Multiple Myeloma Research Foundation Multiple Myeloma Research Foundation, The Leukemia & Lymphoma Society The Leukemia & Lymphoma Society, BCRP Blood Cancer Research Partnership, Adam S Sperling, MD PhD, Giada Bianchi, MD, Jacob P. Laubach, MD, Jorge J. Castillo, MD, Nikhil C. Munshi, MD, Kenneth C. Anderson, MD, Paul G. Richardson, MD, Lorenzo Trippa, Irene M. Ghobrial, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1898.
DOI: https://doi.org/10.1182/blood-2019-129103
Published: 2019
Journal Articles

Favorable Progression-Free Survival Associated with Immune Bio-Markers Modulated By Pomalidomide in Relapsed/Refractory Multiple Myeloma: An Analysis of Phase III Study

Rao Prabhala, PhD, Mehmet Kemal Samur, PhD, Srikanth Talluri, PhD, Megan Stekla, BS, Chaitanya Yenumula, MD, Michael A Lopez, Sanika Derebail, Lakshmi B. Potluri, Angela Wang, Aishwarya Katiki, Sahan D. Vangala, Eric Haas, Michael J Buonopane, BS, Alexander T Heubeck, BS, Mariateresa Fulciniti, PhD, Raphael Szalat, MD, Suzan Lazo-Kallanian, BS, Kevin Hong, Teresa Peluso, John Daley, PhD, Tsvetan Biyukov, MD, Albert Oriol, William E. Pierceall, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Anjan Thakurta, Hervé Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1784.
DOI: https://doi.org/10.1182/blood-2019-131257
Published: 2019