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Journal Articles

Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A

Jesse D. Lai, Paul C. Moorehead, Kate Sponagle, Katharina N. Steinitz, Birgit M. Reipert, Christine Hough, David Lillicrap

Blood (2016) 127 (26): 3439–3449.

https://doi.org/10.1182/blood-2015-11-679282

Published: 2016

Includes: Supplemental data

Journal Articles

Characterization of Type 2N Von Willebrand Disease Mutations Using Ιn Vitro and Ιn Vivo Mouse Models

Laura L Swystun, PhD, Ilinca Georgescu, Meghan Deforest, Mia Golder, PhD, Kate Sponagle, Christine Brown, Colleen Notley, David Lillicrap, MD

Blood (2014) 124 (21): 471.

https://doi.org/10.1182/blood.V124.21.471.471

Published: 2014

Journal Articles

Age-Related Increases in Plasma Factor VIII and Von Willebrand Factor in a C57BL/6 Mouse Model Are Associated with Increased Factor VIII and Von Willebrand Factor Gene Expression and Reduced Expression of the Clearance Receptor, Stabilin-2

Silvia Albánez, MSc, Alison Michels, BSc, Kate Sponagle, David Lillicrap, MD

Blood (2014) 124 (21): 4228.

https://doi.org/10.1182/blood.V124.21.4228.4228

Published: 2014

Journal Articles

Administration of Dexamethasone during Initial Exposure to Factor VIII Prevents the Development of Anti-Factor VIII Antibodies and Increases the Proportion of Thymic but Not Splenic Regulatory T Cells in the Exon 16 Knockout C57Bl6 Hemophilia Α Mouse Model

Maria T. Georgescu, BScH, Paul C. Moorehead, MDMS, MSc, Kate Sponagle, Birgit M. Reipert, PhD, Christine Hough, PhD, David Lillicrap, MD

Blood (2014) 124 (21): 237.

https://doi.org/10.1182/blood.V124.21.237.237

Published: 2014

Journal Articles

Histones Induce Endothelial Von Willebrand Factor Release and Subsequent Platelet Capture in In Vitro and In Vivo Models

Alison Michels, BSc, Laura L Swystun, PhD, Silvia Albánez, MSc, Jeffrey Mewburn, Kate Sponagle, David Lillicrap, MD

Blood (2014) 124 (21): 2768.

https://doi.org/10.1182/blood.V124.21.2768.2768

Published: 2014

Journal Articles

Immunization Against Influenza but Not MMR Modulates the Anti-Factor VIII Immune Response in Hemophilia Α Mice

Jesse Lai, BSc, Paul C. Moorehead, MDMS, MSc, Kate Sponagle, Katharina Nora Steinitz, PhD, Birgit M Reipert, PhD, Christine Hough, PhD, David Lillicrap, MD

Blood (2014) 124 (21): 1501.

https://doi.org/10.1182/blood.V124.21.1501.1501

Published: 2014

Journal Articles

Administration of Dexamethasone during Initial Exposure to Factor VIII Induces Durable and Antigen-Specific Tolerance to Factor VIII in Hemophilia Α Mice with a Humanized Major Histocompatibility Complex II Transgene

Paul C. Moorehead, MDMS, MSc, Maria T. Georgescu, BScH, Alice S. van Velzen, MD, Kate Sponagle, Barbara Vidal, MSc, Birgit M. Reipert, PhD, Katharina Nora Steinitz, PhD, Christine Hough, PhD, David Lillicrap, MD

Blood (2014) 124 (21): 1489.

https://doi.org/10.1182/blood.V124.21.1489.1489

Published: 2014

Journal Articles

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Yasuaki Shida, Natalia Rydz, David Stegner, Christine Brown, Jeffrey Mewburn, Kate Sponagle, Ozge Danisment, Bredon Crawford, Barbara Vidal, Carol A. Hegadorn, Cynthia M. Pruss, Bernhard Nieswandt, David Lillicrap

Blood (2014) 124 (11): 1799–1807.

https://doi.org/10.1182/blood-2013-09-521484

Published: 2014

Journal Articles

Myeloid-Derived Suppressor Cell (MDSC) Dynamics In FVIII-Exposed Hemophilia A Mice: Novel Therapeutic Implications

Brooke Snetsinger, MSc, Caroline Lin, BSc, Willy Weng, BSc, Alyssa Cull, MSc, Kate Sponagle, Christine Hough, PhD, David Lillicrap, Michael J. Rauh, MD, PhD

Blood (2013) 122 (21): 3569.

https://doi.org/10.1182/blood.V122.21.3569.3569

Published: 2013

Journal Articles

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

Laura L. Swystun, PhD, Colleen Notley, Kate Sponagle, Paula D. James, MD, David Lillicrap

Blood (2013) 122 (21): 2340.

https://doi.org/10.1182/blood.V122.21.2340.2340

Published: 2013

Journal Articles

Platelet-Mediated Mechanical Tensile Force Influences ADAMTS13 Localization and Regulation Of Thrombus Development At The Site Of Platelet Accumulation

Yasuaki Shida, MD, PhD, Laura L. Swystun, PhD, Christine Brown, Jeff Mewburn, Kate Sponagle, Ozge Danisment, Jacob Riches, Christine Hough, PhD, David Lillicrap

Blood (2013) 122 (21): 454.

https://doi.org/10.1182/blood.V122.21.454.454

Published: 2013

Journal Articles

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Natalia Rydz, Laura L. Swystun, Colleen Notley, Andrew D. Paterson, J. Jacob Riches, Kate Sponagle, Boonchai Boonyawat, Robert R. Montgomery, Paula D. James, David Lillicrap

Blood (2013) 121 (26): 5228–5237.

https://doi.org/10.1182/blood-2012-10-457507

Published: 2013

Includes: Supplemental data

Journal Articles

Surgical Injury Alone Does Not Provoke the Development of Factor VIII Inhibitors in Mouse Models of Hemophilia A

Paul C Moorehead, MD, MS, Braden Waters, PhD, Kate Sponagle, Katharina Nora Steinitz, PhD, Birgit M Reipert, PhD, David Lillicrap, MD

Blood (2012) 120 (21): 627.

https://doi.org/10.1182/blood.V120.21.627.627

Published: 2012

Journal Articles

Comprehensive In Vitro and In Vivo Characterization of Loss and Gain-of-Function Von Willebrand Factor Collagen Binding Variants Using a Mouse Model System,

Yasuaki Shida, MD, PhD, Christine Brown, Jeff Mewburn, Kate Sponagle, Ozge Danisment, Barbara Vidal, Carol A Heagadorn, David Lillicrap, MD

Blood (2011) 118 (21): 3266.

https://doi.org/10.1182/blood.V118.21.3266.3266

Published: 2011

Journal Articles

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

Cynthia M. Pruss, Mia Golder, Andrea Bryant, Carol A. Hegadorn, Erin Burnett, Kimberly Laverty, Kate Sponagle, Aly Dhala, Colleen Notley, Sandra Haberichter, David Lillicrap

Blood (2011) 117 (16): 4358–4366.

https://doi.org/10.1182/blood-2010-08-303727

Published: 2011

Journal Articles

Mouse Models of the Common, Recurring Type 1 von Willebrand Disease Mutations Y1584C and R1205H

Cynthia M. Pruss, PhD, Mia Golder, Andrea Bryant, Erin Burnett, Kate Sponagle, Carol Hegadorn, Sandra L. Haberichter, PhD, David Lillicrap, MD

Blood (2010) 116 (21): 22.

https://doi.org/10.1182/blood.V116.21.22.22

Published: 2010

Journal Articles

A Modified Model of Type 2B von Willebrand Disease: Taking ADAMTS13-Mediated Cleavage out of the Equation

Mia Golder, Cynthia M. Pruss, PhD, Kate Sponagle, Carol Hegadorn, Erin Burnett, Andrea Bryant, David Lillicrap, MD

Blood (2010) 116 (21): 23.

https://doi.org/10.1182/blood.V116.21.23.23

Published: 2010

Journal Articles

Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions

Mia Golder, Cynthia M. Pruss, Carol Hegadorn, Jeffrey Mewburn, Kimberly Laverty, Kate Sponagle, David Lillicrap

Blood (2010) 115 (23): 4862–4869.

https://doi.org/10.1182/blood-2009-11-253120

Published: 2010

Journal Articles

In Vitro and In Vivo Mouse Models of the Type 1 Von Willebrand Disease Mutations Y1584C and R1205H.

Cynthia M. Pruss, BSc, Kate Sponagle, Kimberly Laverty, Carol A. Hegadorn, Yvette Chirinian, Colleen Notley, Mia Golder, David Lillicrap, MD

Blood (2009) 114 (22): 26.

https://doi.org/10.1182/blood.V114.22.26.26

Published: 2009

NARROW

Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A

Characterization of Type 2N Von Willebrand Disease Mutations Using Ιn Vitro and Ιn Vivo Mouse Models

Age-Related Increases in Plasma Factor VIII and Von Willebrand Factor in a C57BL/6 Mouse Model Are Associated with Increased Factor VIII and Von Willebrand Factor Gene Expression and Reduced Expression of the Clearance Receptor, Stabilin-2

Administration of Dexamethasone during Initial Exposure to Factor VIII Prevents the Development of Anti-Factor VIII Antibodies and Increases the Proportion of Thymic but Not Splenic Regulatory T Cells in the Exon 16 Knockout C57Bl6 Hemophilia Α Mouse Model

Histones Induce Endothelial Von Willebrand Factor Release and Subsequent Platelet Capture in In Vitro and In Vivo Models

Immunization Against Influenza but Not MMR Modulates the Anti-Factor VIII Immune Response in Hemophilia Α Mice

Administration of Dexamethasone during Initial Exposure to Factor VIII Induces Durable and Antigen-Specific Tolerance to Factor VIII in Hemophilia Α Mice with a Humanized Major Histocompatibility Complex II Transgene

Analysis of the role of von Willebrand factor, platelet glycoprotein VI-, and α2β1-mediated collagen binding in thrombus formation

Myeloid-Derived Suppressor Cell (MDSC) Dynamics In FVIII-Exposed Hemophilia A Mice: Novel Therapeutic Implications

Regulation Of Factor VIII Clearance By Mannose-Binding Lectins

Platelet-Mediated Mechanical Tensile Force Influences ADAMTS13 Localization and Regulation Of Thrombus Development At The Site Of Platelet Accumulation

The C-type lectin receptor CLEC4M binds, internalizes, and clears von Willebrand factor and contributes to the variation in plasma von Willebrand factor levels

Surgical Injury Alone Does Not Provoke the Development of Factor VIII Inhibitors in Mouse Models of Hemophilia A

Comprehensive In Vitro and In Vivo Characterization of Loss and Gain-of-Function Von Willebrand Factor Collagen Binding Variants Using a Mouse Model System,

Pathologic mechanisms of type 1 VWD mutations R1205H and Y1584C through in vitro and in vivo mouse models

Mouse Models of the Common, Recurring Type 1 von Willebrand Disease Mutations Y1584C and R1205H

A Modified Model of Type 2B von Willebrand Disease: Taking ADAMTS13-Mediated Cleavage out of the Equation

Mutation-specific hemostatic variability in mice expressing common type 2B von Willebrand disease substitutions

In Vitro and In Vivo Mouse Models of the Type 1 Von Willebrand Disease Mutations Y1584C and R1205H.

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American Society of Hematology

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American Society of Hematology

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