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Journal Articles

(Peri)Centromeric Rearrangements Are Recurrent Recombination Events in Complex-Karyotype Chronic Lymphocytic Leukemia

Maria-Veronica Teleanu, Karlheinz Holzmann, Jennifer Edelmann

Blood (2022) 140 (Supplement 1): 4115–4116.

DOI: https://doi.org/10.1182/blood-2022-166281

Published: 2022

Journal Articles

Multiplatform Profiling Characterizes Functional Networks in Genomically Stable and Instable Chronic Lymphocytic Leukemia

Blood (2020) 136 (Supplement 1): 12–13.

DOI: https://doi.org/10.1182/blood-2020-141552

Published: 2020

Journal Articles

Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis

Jennifer Edelmann, MD PhD, Arran Dokal, MSc, PhD, Karlheinz Holzmann, Dr. rer. nat., David James Britton, BSc, PhD, Emma Vilventhraraja, MSc, PhD, Ryan Jack Smith, PhD, Mark S Cragg, Prof, Andrejs Braun, PhD, Hartmut Döhner, MD, Pedro Cutillas, PhD, John G. Gribben, MD DSc

Blood (2019) 134 (Supplement_1): 1579.

DOI: https://doi.org/10.1182/blood-2019-128704

Published: 2019

Journal Articles

MYC Pathway Activation Is Frequently Observed in Treatment-Naive CLL and Defines a Subgroup with Particular Benefit from the Addition of Rituximab to Chemotherapy

Johannes Bloehdorn, MD, Julia Krzykalla, MSc, Billy Michael Chelliah Jebaraj, PhD, Karlheinz Holzmann, Dr. rer. nat., Jasmin Bahlo, PhD, Sandra Robrecht, PhD, Kathryn Humphrey, Michael Wenger, Eugen Tausch, MD, Christof Schneider, MD, Lars Bullinger, MD, Kirsten Fischer, MD, Michael Hallek, MD, Daniel Mertens, Axel Benner, Hartmut Döhner, MD, Stephan Stilgenbauer

Blood (2018) 132 (Supplement 1): 1866.

DOI: https://doi.org/10.1182/blood-2018-99-116937

Published: 2018

Journal Articles

Anti-CD20 Monoclonal Antibodies Hijack the B-Cell Receptor Signaling Cascade Thereby Activating the NOTCH1 Signaling Pathway

Jennifer Edelmann, MD, David James Britton, BSc, PhD, Emma Vilventhraraja, MSc, PhD, Arran Dokal, MSc, PhD, Karlheinz Holzmann, Dr. rer. nat., Mark C Cragg, Andrejs Braun, PhD, Pedro Cutillas, PhD, John G. Gribben

Blood (2018) 132 (Supplement 1): 588.

DOI: https://doi.org/10.1182/blood-2018-99-116490

Published: 2018

Journal Articles

Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia

Fan Wang, Salih Demir, Franziska Gehringer, Clarissa D. Osswald, Felix Seyfried, Stefanie Enzenmüller, Sarah M. Eckhoff, Thomas Maier, Karlheinz Holzmann, Klaus-Michael Debatin, Thomas Wirth, Lüder H. Meyer, Alexey Ushmorov

Blood (2018) 131 (26): 2929–2942.

DOI: https://doi.org/10.1182/blood-2017-10-813576

Published: 2018

Includes: Supplemental data

Journal Articles

High-Resolution SNP-Array Profiling of "Ultra-High Risk" CLL Cases Reveals New Recurrent Genomic Alterations

Jennifer Edelmann, MD PhD, Karlheinz Holzmann, Dr. rer. nat., Eugen Tausch, MD, Anna Dolnik, PhD, Tamara J. Blätte, MSc, Stefan Ibach, Dr, Jenny Saub, Daniel Mertens, PhD, Lars Bullinger, MD, Kirsten Fischer, MD, Valentin Goede, MD, John G. Gribben, MDDSc FMedSci, Michael J. Hallek, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD PhD

Blood (2017) 130 (Supplement 1): 2992.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2992.2992

Published: 2017

Journal Articles

Rituximab Activates NOTCH1 Signaling in CLL Cells and Induces Changes in the Cytokine Repertoire Favoring a Tumor-Protective Microenvironment

Jennifer Edelmann, MD PhD, Karlheinz Holzmann, Dr. rer. nat., Doriana DiBella, Emma Vilventhraraja, Stephen A Beers, PhD, Mark Cragg, PhD, Andrejs Braun, PhD, John G. Gribben, MDDSc FMedSci

Blood (2017) 130 (Supplement 1): 2996.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2996.2996

Published: 2017

Journal Articles

Clonal Evolution in NPM1 Mutated Acute Myeloid Leukemia (AML)

Silke Kapp-Schwoerer, MD, Sibylle Cocciardi, Jan Kroenke, MD, Anna Dolnik, PhD, Tamara J. Blätte, Andrea Corbacioglu, PhD, Verena I. Gaidzik, MD, Peter Paschka, MD, Maria-Veronica Teleanu, MD, Karlheinz Holzmann, PhD, Gudrun Göhring, MD, Felicitas Thol, MD, Michael Heuser, MD, Arnold Ganser, MD PhD, Richard F. Schlenk, MD, Hartmut Döhner, Prof. Dr., Lars Bullinger, MD, Konstanze Döhner, MD

Blood (2015) 126 (23): 1381.

DOI: https://doi.org/10.1182/blood.V126.23.1381.1381

Published: 2015

Journal Articles

Mutational Landscape of Del(9q) Acute Myeloid Leukemia (AML)

Anna Dolnik, PhD, Sundaram R. Chakkarappan, PhD, Tamara J. Blätte, Sibylle Cocciardi, Jan Krönke, MD, Corbacioglu Andrea, PhD, Karlheinz Holzmann, PhD, Peter Paschka, MD, Frank G. Rücker, MD, Silke Kapp-Schwoerer, MD, Verena I. Gaidzik, MD, Richard F. Schlenk, MD, Hartmut Döhner, Prof. Dr., Konstanze Döhner, MD, Lars Bullinger, MD

Blood (2015) 126 (23): 3844.

DOI: https://doi.org/10.1182/blood.V126.23.3844.3844

Published: 2015

Journal Articles

High Resolution Genomic Profiling of Primary “Ultra High Risk” and Refractory Chronic Lymphocytic Leukemia: Results from the CLL2O Trial

Jennifer Edelmann, MD, Jenny Saub, Stefan Ibach, Karlheinz Holzmann, PhD, Eugen Tausch, MD, Johannes Bloehdorn, MD, Daniel Mertens, PhD, Thorsten Zenz, MD, Florence Cymbalista, MD, Veronique Leblond, MD PhD, Alain Delmer, MD PhD, John G. Gribben, MD DSc, Michael Hallek, MD, Hartmut Döhner, MD, Stephan Stilgenbauer, MD

Blood (2014) 124 (21): 3288.

DOI: https://doi.org/10.1182/blood.V124.21.3288.3288

Published: 2014

Journal Articles

FOXO1 repression contributes to block of plasma cell differentiation in classical Hodgkin lymphoma

Blood (2014) 124 (20): 3118–3129.

DOI: https://doi.org/10.1182/blood-2014-07-590570

Published: 2014

Includes: Supplemental data

Journal Articles

Clonal evolution in relapsed NPM1 -mutated acute myeloid leukemia

Blood (2013) 122 (1): 100–108.

DOI: https://doi.org/10.1182/blood-2013-01-479188

Published: 2013

Includes: Supplemental data

Journal Articles

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

Blood (2012) 120 (24): 4783–4794.

DOI: https://doi.org/10.1182/blood-2012-04-423517

Published: 2012

Includes: Supplemental data

Journal Articles

High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

Blood (2012) 119 (10): e67–e75.

DOI: https://doi.org/10.1182/blood-2011-09-380444

Published: 2012

Includes: Supplemental data

Journal Articles

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

Blood (2012) 119 (9): 2114–2121.

DOI: https://doi.org/10.1182/blood-2011-08-375758

Published: 2012

Includes: Supplemental data

Journal Articles

Genome-Wide Genotyping of Acute Myeloid Leukemia with t(9;11) Reveals New Recurrent Genomic Alterations,

Michael W.M. Kühn, MD, Lars Bullinger, Jennifer Edelmann, MD, Jan Krönke, MD, Gröschel Stefan, MD, Frank G. Rücker, Peter Paschka, MD, Verena I. Gaidzik, MD, Karlheinz Holzmann, PhD, Richard F. Schlenk, MD, Hartmut Döhner, MD, Konstanze Döhner, MD

Blood (2011) 118 (21): 3546.

DOI: https://doi.org/10.1182/blood.V118.21.3546.3546

Published: 2011

Journal Articles

TP53 Alterations in Acute Myeloid Leukemia with Complex Karyotype Correlate with Specific Copy Number Alterations, Monosomal Karyotype, and Dismal Outcome,

Blood (2011) 118 (21): 3558.

DOI: https://doi.org/10.1182/blood.V118.21.3558.3558

Published: 2011

Journal Articles

High-Resolution SNP-Array Profiling of Chronic Lymphocytic Leukemia

Jennifer Edelmann, MD, Karlheinz Holzmann, PhD, W.M. Michael Kühn, MD, Lars Bullinger, MD, Ina Radtke, MD, PhD, Xiaoping Su, PhD, Jing Ma, Ph.D., Dirk Winkler, MD, Andreas Buehler, Michael Hallek, M.D., James R. Downing, MD, Stephan Stilgenbauer, MD, Hartmut Doehner, MD

Blood (2010) 116 (21): 50.

DOI: https://doi.org/10.1182/blood.V116.21.50.50

Published: 2010

Journal Articles

Dihydrofolate Reductase Deficiency Is Caused by a Homozygous DHFR Mutation and Leads to Congenital Megaloblastic Anemia and Cerebral Folate Deficiency

Holger Cario, MD, Desiree E.C. Smith, PhD, Henk J. Blom, PhD, Harald Bode, MD, Nenad Blau, PhD, Karlheinz Holzmann, PhD, Ulrich Pannicke, Elisabeth Kohne, MD, Klaus-Michael Debatin, MD, Yvo M. Smulders, MD, Klaus Schwarz

Blood (2010) 116 (21): 1006.

DOI: https://doi.org/10.1182/blood.V116.21.1006.1006

Published: 2010

NARROW

(Peri)Centromeric Rearrangements Are Recurrent Recombination Events in Complex-Karyotype Chronic Lymphocytic Leukemia

Multiplatform Profiling Characterizes Functional Networks in Genomically Stable and Instable Chronic Lymphocytic Leukemia

Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis

MYC Pathway Activation Is Frequently Observed in Treatment-Naive CLL and Defines a Subgroup with Particular Benefit from the Addition of Rituximab to Chemotherapy

Anti-CD20 Monoclonal Antibodies Hijack the B-Cell Receptor Signaling Cascade Thereby Activating the NOTCH1 Signaling Pathway

Tight regulation of FOXO1 is essential for maintenance of B-cell precursor acute lymphoblastic leukemia

High-Resolution SNP-Array Profiling of "Ultra-High Risk" CLL Cases Reveals New Recurrent Genomic Alterations

Rituximab Activates NOTCH1 Signaling in CLL Cells and Induces Changes in the Cytokine Repertoire Favoring a Tumor-Protective Microenvironment

Clonal Evolution in NPM1 Mutated Acute Myeloid Leukemia (AML)

Mutational Landscape of Del(9q) Acute Myeloid Leukemia (AML)

High Resolution Genomic Profiling of Primary “Ultra High Risk” and Refractory Chronic Lymphocytic Leukemia: Results from the CLL2O Trial

FOXO1 repression contributes to block of plasma cell differentiation in classical Hodgkin lymphoma

Clonal evolution in relapsed NPM1 -mutated acute myeloid leukemia

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

Genome-Wide Genotyping of Acute Myeloid Leukemia with t(9;11) Reveals New Recurrent Genomic Alterations,

TP53 Alterations in Acute Myeloid Leukemia with Complex Karyotype Correlate with Specific Copy Number Alterations, Monosomal Karyotype, and Dismal Outcome,

High-Resolution SNP-Array Profiling of Chronic Lymphocytic Leukemia

Dihydrofolate Reductase Deficiency Is Caused by a Homozygous DHFR Mutation and Leads to Congenital Megaloblastic Anemia and Cerebral Folate Deficiency

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American Society of Hematology

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American Society of Hematology

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