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Journal Articles

Interim Subgroup Analysis of the Effectiveness and Safety of Damoctocog Alfa Pegol Prophylaxis in Previously Treated Patients with Hemophilia A Treated Every 5 or Every 7 Days: Results from the Real-World Observational HEM-POWR Study

Mark T Reding, María Teresa Alvarez Román, Martin Sanabria, Giancarlo Castaman, Maissaa Janbain, Tadashi Matsushita, Karina Meijer, Kathrin Schmidt, Johannes Oldenburg

Blood (2022) 140 (Supplement 1): 5612–5614.

https://doi.org/10.1182/blood-2022-169159

Published: 2022

Journal Articles

Colorectal Cancer Screening in Patients with Inherited Bleeding Disorders: High Cancer Detection Rate in Hemophilia Patients

Eva Kempers, Calvin B. van Kwawegen, Joke de Meris, Saskia E.M. Schols, Paula F. Ypma, Floor C.J.I. Moenen, Lize F.D. Van Vulpen, Michiel Coppens, Johanna G. van der Bom, Karin Fijnvandraat, Karina Meijer, Jeroen C.J. Eikenboom, Samantha C. Gouw, Frank W.G. Leebeek, Marieke J.H.A. Kruip

Blood (2022) 140 (Supplement 1): 1416–1417.

https://doi.org/10.1182/blood-2022-157537

Published: 2022

Journal Articles

First Data from the Phase 3 HOPE-B Gene Therapy Trial: Efficacy and Safety of Etranacogene Dezaparvovec (AAV5-Padua hFIX variant; AMT-061) in Adults with Severe or Moderate-Severe Hemophilia B Treated Irrespective of Pre-Existing Anti-Capsid Neutralizing Antibodies

Steven W. Pipe, MD, Michael Recht, MD PhD, Nigel S. Key, MD, Frank W.G. Leebeek, MD PhD, Giancarlo Castaman, MD, Susan U. Lattimore, R.N., Paul Van Der Valk, Kathelijne Peerlinck, MD PhD, Michiel Coppens, MD, Niamh O'Connell, MD PhD, John Pasi, MB, ChB, PhD FRCP, FRCPath, FRCPCH, Peter Kampmann, MD, Karina Meijer, MD PhD, Annette von Drygalski, MD Pharm D, Guy Young, MD, Cedric Hermans, MDMRCP,PhD, Jan Astermark, MD PhD, Robert Klamroth, MD PhD, Richard S. Lemons, MD, Nathan Visweshwar, MD, Shelley Crary, MD MS, Rashid Kazmi, MBBS, Emily Symington, Miguel A. Escobar, MD, Esteban Gomez, MD, Rebecca Kruse-Jarres, MD, Adam Kotowski, MD, Doris Quon, MD PhD, Michael Wang, MD, Allison P. Wheeler, MD, Eileen K Sawyer, PhD, Stephanie Verweij, BSc, Valerie Colletta, MSc, Naghmana Bajma, MD, Robert Gut, MD PhD, Wolfgang A. Miesbach, MD PhD

Blood (2020) 136 (Supplement_2): LBA-6.

https://doi.org/10.1182/blood-2020-143560

Published: 2020

Journal Articles

Semiautomatic VWF Multimer Densitometric Analysis: Validation of the Clinical Accuracy and Clinical Implications in Von Willebrand Disease

Ferdows Atiq, Johan Boender, MD, Marjon H. Cnossen, MD PhD, Johanna G van der Bom, MD PhD, Karin Fijnvandraat, MD PhD, Joke de Meris, Moniek P.M. de Maat, PhD, Karin P.M. Van Galen, MD MSc, PhD, Britta A.P. Laros-Van Gorkom, MD PhD, Karina Meijer, MD PhD, Jeroen C.J. Eikenboom, MD PhD, Frank W.G. Leebeek, MD PhD

Blood (2020) 136 (Supplement 1): 15–16.

https://doi.org/10.1182/blood-2020-142287

Published: 2020

Journal Articles

AMT-060 Gene Therapy in Adults with Severe or Moderate-Severe Hemophilia B Confirm Stable FIX Expression and Durable Reductions in Bleeding and Factor IX Consumption for up to 5 Years

Frank W.G. Leebeek, MD PhD, Karina Meijer, MD PhD, Michiel Coppens, MD, Peter Kampmann, MD, Robert Klamroth, Roger Schutgens, MD PhD MSc, Giancarlo Castaman, MD, Erhard Seifried, MD PhD, Joachim Schwaeble, Halvard Bönig, Eileen K Sawyer, PhD, Wolfgang A. Miesbach, MD

Blood (2020) 136 (Supplement 1): 26.

https://doi.org/10.1182/blood-2020-139225

Published: 2020

Journal Articles

Stable FIX Expression and Durable Reductions in Bleeding and Factor IX Consumption for up to 4 Years Following AMT-060 Gene Therapy in Adults with Severe or Moderate-Severe Hemophilia B

Wolfgang Miesbach, MD PhD, Karina Meijer, Michiel Coppens, MD, Peter Kampmann, MD, Dr. Klamroth, Roger Schutgens, MD PhD MSc, Giancarlo Castaman, MD, Erhard Seifried, MD PhD, Joachim Schwaeble, Halvard Bönig, Eileen K Sawyer, PhD, Frank W.G. Leebeek, MD PhD

Blood (2019) 134 (Supplement_1): 2059.

https://doi.org/10.1182/blood-2019-122535

Published: 2019

Journal Articles

Real-World Effectiveness and Safety of BAY 94-9027 (Damoctocog Alfa Pegol) in Previously Treated Patients with Hemophilia A (HEM-POWR): Online Patient Portal and LIFE-ACTIVE Sub-Study

Johannes Oldenburg, María Teresa Alvarez Román, Giancarlo Castaman, Maissaa Janbain, MD, Tadashi Matsushita, Karina Meijer, Sabine Friedl, Martin Sanabria, Mark Reding

Blood (2019) 134 (Supplement_1): 4943.

https://doi.org/10.1182/blood-2019-128140

Published: 2019

Journal Articles

Reduced incidence of vein occlusion and postthrombotic syndrome after immediate compression for deep vein thrombosis

Elham E. Amin, Ingrid M. Bistervels, Karina Meijer, Lidwine W. Tick, Saskia Middeldorp, Guy Mostard, Marlène van de Poel, Erik H. Serné, Hans M. Otten, Edith M. Klappe, Manuela A. Joore, Hugo ten Cate, Marije ten Wolde, Arina J. ten Cate-Hoek

Blood (2018) 132 (21): 2298–2304.

https://doi.org/10.1182/blood-2018-03-836783

Published: 2018

Journal Articles

Gene therapy with adeno-associated virus vector 5–human factor IX in adults with hemophilia B

Wolfgang Miesbach, Karina Meijer, Michiel Coppens, Peter Kampmann, Robert Klamroth, Roger Schutgens, Marco Tangelder, Giancarlo Castaman, Joachim Schwäble, Halvard Bonig, Erhard Seifried, Federica Cattaneo, Christian Meyer, Frank W. G. Leebeek

Blood (2018) 131 (9): 1022–1031.

https://doi.org/10.1182/blood-2017-09-804419

Published: 2018

Includes: Supplemental data

Journal Articles

Interim Results from a Dose Escalating Study of AMT-060 (AAV5-hFIX) Gene Transfer in Adult Patients with Severe Hemophilia B

Frank W.G. Leebeek, MD PhD, Marco Tangelder, MD PhD, Karina Meijer, MD PhD, Giancarlo Castaman, Federica Cattaneo, MD, Michiel Coppens, MD PhD, Peter Kampmann, MD, Robert Klamroth, Roger E.G. Schutgens, MD PhD, Erhard Seifried, MD PhD, Joachim Schwaeble, MD, Halvard Boenig, MD PhD, Maaike Hendriks, Deya Corzo, MD FAAP, Wolfgang A. Miesbach, MD PhD

Blood (2016) 128 (22): 2314.

https://doi.org/10.1182/blood.V128.22.2314.2314

Published: 2016

Journal Articles

No Association Between Normalization of VWF Levels and Bleeding Phenotype in Patients with Type 1 VWD - from the Win Study

Johan Boender, MD, Jeroen Eikenboom, MD PhD, Karin Fijnvandraat, MD PhD, Waander van Heerde, PhD, Karina Meijer, MD PhD, Evelien Mauser-Bunschoten, MD PhD, Marjon Cnossen, MD PhD, Joke de Meris, Britta Laros-van Gorkom, MD PhD, Anske van der Bom, MD PhD, Frank W.G. Leebeek, MD PhD

Blood (2016) 128 (22): 2577.

https://doi.org/10.1182/blood.V128.22.2577.2577

Published: 2016

Journal Articles

Incidence and Risk Factors for Venous Thrombosis in Human Immunodeficiency Virus (HIV) Infection, Data from the Dutch Athena Cohort Study

James Francis Borjas-Howard, MD MSc, Casper Rokx, MD PhD, Colette Smit, PhD, Ferdinand Wit, MD PhD, Elise Pieterman, MD MSc, Karina Meijer, MD PhD, Bart Rijnders, MD PhD, Wouter Bierman, MD PhD, Vladimir Tichelaar, MD PhD

Blood (2016) 128 (22): 271.

https://doi.org/10.1182/blood.V128.22.271.271

Published: 2016

Journal Articles

The Bleeding Risk of Vitamin K Antagonists Hardly Increases after the Age of 80 Years: Data from a Large Real-Life Cohort Study

Hilde Kooistra, MD, Agneta Calf, MD, Margriet Piersma-Wichers, MD, Gerbrand Izaks, MD, Nic Veeger, MSc, Karina Meijer, MD PhD

Blood (2015) 126 (23): 891.

https://doi.org/10.1182/blood.V126.23.891.891

Published: 2015

Journal Articles

von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease

Yvonne V. Sanders, Dafna Groeneveld, Karina Meijer, Karin Fijnvandraat, Marjon H. Cnossen, Johanna G. van der Bom, M. Coppens, Joke de Meris, Britta A. P. Laros-van Gorkom, Eveline P. Mauser-Bunschoten, Frank W. G. Leebeek, Jeroen Eikenboom, the WiN study group

Blood (2015) 125 (19): 3006–3013.

https://doi.org/10.1182/blood-2014-09-603241

Published: 2015

Includes: Supplemental data

Journal Articles

Towards Successful Implementation of Pharmacokinetic-Guided Prophylactic Dosing of Clotting Factor Concentrate in Hemophilia; The Do’s and Don’ts after Discrete Choice Experiment Analysis

Janske Lock, MD PhDstudent, Esther W. de Bekker-Grob, PhD, Gamze Urhan, MD, Saskia Middeldorp, MD PhD, Marjolein Peters, MD PhD, Karina Meijer, MD PhD, Rienk Y.J. Tamminga, MD PhD, Britta Laros-van Gorkum, MD PhD, Paul Brons, Felix J.M. Van der Meer, MD PhD, Mariette H.E. Driessens, PhD, Peter W. Collins, MD, Karin Fijnvandraat, MD PhD, Frank W.G. Leebeek, MD PhD, Marjon H. Cnossen, MD PhD

Blood (2014) 124 (21): 5038.

https://doi.org/10.1182/blood.V124.21.5038.5038

Published: 2014

Journal Articles

Single-Nucleotide Variation Spectrum of the Factor XI Gene in Women with Heavy Menstrual Bleeding

Sophie Wiewel-Verschueren, MD, André B Mulder, MDPhD, Karina Meijer, MD PhD, René Mulder, PhD

Blood (2014) 124 (21): 4213.

https://doi.org/10.1182/blood.V124.21.4213.4213

Published: 2014

Journal Articles

Targeting Clotting Factor VIII Plasma Values in the Perioperative Setting in Hemophilia a: “Tackling a Moving Target” (“OPTI-CLOT” Studies)

Janske Lock, MD PhDstudent, Hendrika C.A.M. Hazendonk, MD PhDstudent, Ron A.A. Mathôt, Prof. Dr., Karina Meijer, MD PhD, Marjolein Peters, MD PhD, Paul Brons, Felix J.M. Van der Meer, MD PhD, Hannan Bouzariouh, MD, Mariette H.E. Driessens, PhD, Karin Fijnvandraat, MD PhD, Frank W.G. Leebeek, MD PhD, Marjon H. Cnossen, MD PhD

Blood (2014) 124 (21): 5031.

https://doi.org/10.1182/blood.V124.21.5031.5031

Published: 2014

Journal Articles

Incidence of Thrombotic Events in Patients Admitted to a Dedicated Tuberculosis Center in the Netherlands

Jaime Borjas-Howard, MD M.Sc., Wouter FW Bierman, MD, PhD, Tjip S van der Werf, MD, PhD, Karina Meijer, MD PhD, Vladimir Tichelaar, MD PhD

Blood (2014) 124 (21): 2860.

https://doi.org/10.1182/blood.V124.21.2860.2860

Published: 2014

Journal Articles

A Systematic Review On Different Prothrombin Complex Concentrate Strategies To Reverse Vitamin K Antagonist Therapy

Nakisa Khorsand, Pharm D, Hilde A.M. Kooistra, MD, Reinier M. van Hest, Pharm D, PhD, Nic J.G.M. Veeger, PhD, Karina Meijer, MD PhD

Blood (2013) 122 (21): 3639.

https://doi.org/10.1182/blood.V122.21.3639.3639

Published: 2013

Journal Articles

Clinical Outcome After Occurrence Of Vitamin K-Antagonist Related Major Bleeding Complication: A Two-Year Observational Follow-Up Study

Nakisa Khorsand, Pharm D, Reinier M van Hest, Pharm D, PhD, Shakiba Zahedin Labbaf, MSc, Paula Ypma, MD, Helga W Vermaas, MD, Nic J.G.M. Veeger, PhD, Karina Meijer, MD PhD

Blood (2013) 122 (21): 2382.

https://doi.org/10.1182/blood.V122.21.2382.2382

Published: 2013

NARROW

Interim Subgroup Analysis of the Effectiveness and Safety of Damoctocog Alfa Pegol Prophylaxis in Previously Treated Patients with Hemophilia A Treated Every 5 or Every 7 Days: Results from the Real-World Observational HEM-POWR Study

Colorectal Cancer Screening in Patients with Inherited Bleeding Disorders: High Cancer Detection Rate in Hemophilia Patients

First Data from the Phase 3 HOPE-B Gene Therapy Trial: Efficacy and Safety of Etranacogene Dezaparvovec (AAV5-Padua hFIX variant; AMT-061) in Adults with Severe or Moderate-Severe Hemophilia B Treated Irrespective of Pre-Existing Anti-Capsid Neutralizing Antibodies

Semiautomatic VWF Multimer Densitometric Analysis: Validation of the Clinical Accuracy and Clinical Implications in Von Willebrand Disease

AMT-060 Gene Therapy in Adults with Severe or Moderate-Severe Hemophilia B Confirm Stable FIX Expression and Durable Reductions in Bleeding and Factor IX Consumption for up to 5 Years

Stable FIX Expression and Durable Reductions in Bleeding and Factor IX Consumption for up to 4 Years Following AMT-060 Gene Therapy in Adults with Severe or Moderate-Severe Hemophilia B

Real-World Effectiveness and Safety of BAY 94-9027 (Damoctocog Alfa Pegol) in Previously Treated Patients with Hemophilia A (HEM-POWR): Online Patient Portal and LIFE-ACTIVE Sub-Study

Reduced incidence of vein occlusion and postthrombotic syndrome after immediate compression for deep vein thrombosis

Gene therapy with adeno-associated virus vector 5–human factor IX in adults with hemophilia B

Interim Results from a Dose Escalating Study of AMT-060 (AAV5-hFIX) Gene Transfer in Adult Patients with Severe Hemophilia B

No Association Between Normalization of VWF Levels and Bleeding Phenotype in Patients with Type 1 VWD - from the Win Study

Incidence and Risk Factors for Venous Thrombosis in Human Immunodeficiency Virus (HIV) Infection, Data from the Dutch Athena Cohort Study

The Bleeding Risk of Vitamin K Antagonists Hardly Increases after the Age of 80 Years: Data from a Large Real-Life Cohort Study

von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease

Towards Successful Implementation of Pharmacokinetic-Guided Prophylactic Dosing of Clotting Factor Concentrate in Hemophilia; The Do’s and Don’ts after Discrete Choice Experiment Analysis

Single-Nucleotide Variation Spectrum of the Factor XI Gene in Women with Heavy Menstrual Bleeding

Targeting Clotting Factor VIII Plasma Values in the Perioperative Setting in Hemophilia a: “Tackling a Moving Target” (“OPTI-CLOT” Studies)

Incidence of Thrombotic Events in Patients Admitted to a Dedicated Tuberculosis Center in the Netherlands

A Systematic Review On Different Prothrombin Complex Concentrate Strategies To Reverse Vitamin K Antagonist Therapy

Clinical Outcome After Occurrence Of Vitamin K-Antagonist Related Major Bleeding Complication: A Two-Year Observational Follow-Up Study

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American Society of Hematology

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ASH Publications

American Society of Hematology

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