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Journal Articles

An Important Role for P-Selectin in Thrombotic Microangiopathy

Raymond Adili, Nicole Roads, Hallie Lazaro, Junmei Chen, Dominic W. Chung, José A. López
Journal: Blood
Blood (2024) 144 (Supplement 1): 182.
https://doi.org/10.1182/blood-2024-208039
Published: 2024
Journal Articles

HDL and HDL-Mimetic Nanoparticles Prevent Induced TTP and Interrupt the Course of Ongoing Episodes of the Disease

Reheman Adili, Nicole Roads, Hallie Lazaro, Jeffrey Harris, Minhua Ling, Junmei Chen, José A. López, Dominic W. Chung
Journal: Blood
Blood (2024) 144 (Supplement 1): 184.
https://doi.org/10.1182/blood-2024-199737
Published: 2024
Journal Articles

Streptococcus Gordonii Binds VWF Via Its Sialoglycan-Binding Adhesins Under Shear to Initiate Infective Endocarditis

Martha M.S. Sim, Ava Obenaus, Richard Maldonado, Jennie Le, Lesley Martínez Rodríguez, Barbara Bensing, Paul Sullam, Wendy Thomas, Nathan Sniadecki, Junmei Chen, Jose A. Lopez
Journal: Blood
Blood (2024) 144 (Supplement 1): 3998.
https://doi.org/10.1182/blood-2024-208774
Published: 2024
Journal Articles

A Novel Mouse Model of Acute Sickle Cell Vaso-Occlusion

Reheman Adili, Junmei Chen, Nicole Roads, Hallie Lazaro, Richard Maldonado, Dominic W. Chung, José A. López
Journal: Blood
Blood (2024) 144 (Supplement 1): 5278.
https://doi.org/10.1182/blood-2024-208195
Published: 2024
Journal Articles

Erythrocytes from Sickle Cell Mice Activate the Endothelium and Blood Cells and Induce Vaso-Occlusion When Transfused into ADAMTS13-Deficient Mice: Role of Lipid Degradation

Reheman Adili, Junmei Chen, Nicole Roads, Richard Maldonado, Hallie Lazaro, Dominic W. Chung, Xiaoyun Fu, José A. López
Journal: Blood
Blood (2024) 144 (Supplement 1): 3864.
https://doi.org/10.1182/blood-2024-208264
Published: 2024
Journal Articles

Self-Association of Von Willebrand Factor (VWF) into Prothrombotic Fibers Is Most Potently Enhanced By the Highly Atherogenic Small, Dense Fraction of Low-Density Lipoprotein (sd-LDL)

Junmei Chen, Forrest Nussdorfer, Raymond Adili, Kimsey Platten, Nicole Rhoads, Richard Maldonado, Franklin Reed, Yi Wang, Minhua Ling, Sergio Fazio, Xiaoyun Fu, Nathalie Pamir, Jose A. Lopez, Dominic W. Chung
Journal: Blood
Blood (2023) 142 (Supplement 1): 504.
https://doi.org/10.1182/blood-2023-188325
Published: 2023
Journal Articles

High-Density Lipoprotein Inhibits Microvascular and Arterial Thrombosis in Mice By Attenuating VWF Self-Association

Raymond Adili, Nicole Rhoads, Jeffrey Harris, Minhua Ling, Junmei Chen, Jose A. Lopez, Dominic W. Chung
Journal: Blood
Blood (2023) 142 (Supplement 1): 3936.
https://doi.org/10.1182/blood-2023-178884
Published: 2023
Journal Articles

Steady-State Von Willebrand Factor Antigen Levels Predict Low Platelet Counts and Risk for Complications in Hospitalizations for Painful Sickle Cell Vaso-Occlusive Episodes

Xu Zhang, Binal Shah, Jin Han, Jose A. Lopez, Dominic W. Chung, Junmei Chen, Victor R. Gordeuk, Santosh L. Saraf
Journal: Blood
Blood (2023) 142 (Supplement 1): 2483.
https://doi.org/10.1182/blood-2023-190297
Published: 2023
Journal Articles

Low-density lipoprotein promotes microvascular thrombosis by enhancing von Willebrand factor self-association

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Reheman Adili, Nathalie Pamir, Forrest Nussdorfer, Alexander St. John, Minhua Ling, Jennie Le, Jeff Harris, Nicole Rhoads, Yi Wang, Xiaoyun Fu, Junmei Chen, Sergio Fazio, Jonathan R. Lindner, José A. López
Journal: Blood
Blood (2023) 142 (13): 1156–1166.
https://doi.org/10.1182/blood.2023019749
Published: 2023
Includes: Multimedia, Supplemental data
Journal Articles

Elevated Levels of Low Density Lipoprotein (LDL) Trigger VWF Self-Association into Fibers and Bundles and Potentiate Microvascular Thrombosis

Dominic W. Chung, Kimsey Platten, Koya Ozawa, Raymond Adili, Nathalie Pamir, Forrest D Nussdorfer, Alexander E St. John, Minhua Ling, Jennie Le, Jeff Harris, Junmei Chen, Sergio Fazio, Jonathan Lindner, José A. López
Journal: Blood
Blood (2022) 140 (Supplement 1): 1660–1661.
https://doi.org/10.1182/blood-2022-170092
Published: 2022
Journal Articles

Deletion of platelet CLEC-2 decreases GPIbα-mediated integrin αIIbβ3 activation and decreases thrombosis in TTP

Bojing Shao, Christopher Hoover, Huiping Shi, Yuji Kondo, Robert H. Lee, Junmei Chen, Xindi Shan, Jianhua Song, J. Michael McDaniel, Meixiang Zhou, Samuel McGee, Karen Vanhoorelbeke, Wolfgang Bergmeier, José A. López, James N. George, Lijun Xia
Journal: Blood
Blood (2022) 139 (16): 2523–2533.
https://doi.org/10.1182/blood.2021012896
Published: 2022
Includes: Supplemental data
Journal Articles

Human Platelets Stored at Room Temperature Demonstrate Diminished Resistance to Oxidative Stress Compared to Those Stored at 4°C

Xiaoyun Fu, PhD, Warren Osborn, Yu Shen, Yi Wang, PhD, Jeffrey Miles, Lydia Fang, M.S., Barbara Osborne, RN, Junmei Chen, PhD, José A. López, MDBS, Moritz Stolla, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 24.
https://doi.org/10.1182/blood-2020-143190
Published: 2020
Journal Articles

Targeted Proteomics Reveals That the Dominant Mechanism of Gpibα Loss during Platelet Storage Depends on Temperature of Storage

Moritz Stolla, MD, Yi Wang, PhD, Jeffrey Miles, Barbara Osborne, RN, Yu Shen, Lydia Fang, M.S., Shawn Lawrence Bailey, BS, Warren Osborn, Junmei Chen, PhD, Jose A. Lopez, MDBS, Xiaoyun Fu, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31–32.
https://doi.org/10.1182/blood-2020-143077
Published: 2020
Journal Articles

Plasma Proteomic Profile Associated with Platelet Dysfunction after Trauma

Alexander E St. John, MD, Yi Wang, PhD, Junmei Chen, PhD, Warren Osborn, Xu Wang, MD, Esther Lim, BS, Dominic W. Chung, PhD, Susan Stern, MD, Nathan White, MD, Xiaoyun Fu, PhD, Jose A. Lopez, MDBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 9–10.
https://doi.org/10.1182/blood-2020-141361
Published: 2020
Journal Articles

Recognition of PF4-VWF complexes by heparin-induced thrombocytopenia antibodies contributes to thrombus propagation

Ian Johnston, Amrita Sarkar, Vincent Hayes, Gavin T. Koma, Gowthami M. Arepally, Junmei Chen, Dominic W. Chung, José A. López, Douglas B. Cines, Lubica Rauova, Mortimer Poncz
Journal: Blood
Blood (2020) 135 (15): 1270–1280.
https://doi.org/10.1182/blood.2018881607
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Thrombotic microangiopathy as a cause of cardiovascular toxicity from the BCR-ABL1 tyrosine kinase inhibitor ponatinib

Yllka Latifi, Federico Moccetti, Melinda Wu, Aris Xie, William Packwood, Yue Qi, Koya Ozawa, Weihui Shentu, Eran Brown, Toshiaki Shirai, Owen J. McCarty, Zaverio Ruggeri, Javid Moslehi, Junmei Chen, Brian J. Druker, Jose A. López, Jonathan R. Lindner
Journal: Blood
Blood (2019) 133 (14): 1597–1606.
https://doi.org/10.1182/blood-2018-10-881557
Published: 2019
Includes: Multimedia, Supplemental data
Journal Articles

Platelet-derived TLT-1 is a prognostic indicator in ALI/ARDS and prevents tissue damage in the lungs in a mouse model

Jessica Morales-Ortíz, Victoria Deal, Fiorella Reyes, Gerónimo Maldonado-Martínez, Nahomy Ledesma, Franklin Staback, Cheyanne Croft, Amanda Pacheco, Humberto Ortiz-Zuazaga, C. Christian Yost, Jesse W. Rowley, Bismark Madera, Alex St. John, Junmei Chen, Jose Lopez, Matthew T. Rondina, Robert Hunter, Angelia Gibson, A. Valance Washington
Journal: Blood
Blood (2018) 132 (23): 2495–2505.
https://doi.org/10.1182/blood-2018-03-841593
Published: 2018
Includes: Supplemental data
Journal Articles

Effect of Intravenous and Oral N-Acetylcysteine Treatment in a Patient with Sickle Cell Disease at Disease Baseline

Hasan Tahsin Ozpolat, MD, Junmei Chen, PhD, Xiaoyun Fu, PhD, Warren Osborn, Jennie Le, BS, Minhua Ling, PhD, Sophie Schmitter, BS, Sarah Ruuska, MPH, Dominic W. Chung, PhD, Barbara A Konkle, José A. López, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4911.
https://doi.org/10.1182/blood-2018-99-117087
Published: 2018
Journal Articles

Inflammation, von Willebrand factor, and ADAMTS13

Junmei Chen, Dominic W. Chung
Journal: Blood
Blood (2018) 132 (2): 141–147.
https://doi.org/10.1182/blood-2018-02-769000
Published: 2018
Journal Articles

Identification of extant vertebrate Myxine glutinosa VWF: evolutionary conservation of primary hemostasis

Marianne A. Grant, David L. Beeler, Katherine C. Spokes, Junmei Chen, Harita Dharaneeswaran, Tracey E. Sciuto, Ann M. Dvorak, Gianluca Interlandi, José A. Lopez, William C. Aird
Journal: Blood
Blood (2017) 130 (23): 2548–2558.
https://doi.org/10.1182/blood-2017-02-770792
Published: 2017
Includes: Supplemental data