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Journal Articles

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Chiara F Magnani, Renier Myburgh, Norman F Russkamp, Steve Pascolo, Judith A Shizuru, Dario Neri, Markus G Manz

Blood (2021) 138 (Supplement 1): 2808.

DOI: https://doi.org/10.1182/blood-2021-145195

Published: 2021

Journal Articles

Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

Blood (2021) 138 (Supplement 1): 3885.

DOI: https://doi.org/10.1182/blood-2021-149306

Published: 2021

Journal Articles

Selective Targeting of Immune Modulatory Proteins to Mitigate Fibrosis and Inflammation in Sclerodermatous Graft-Vs-Host Disease

Lu Cui, Cristabelle De Souza, Tristan Lerbs, Jessica Poyser, Maryam Kooshesh, Atif Saleem, Kerri Rieger, Ryanne Brown, Bernice Kwong, Sebastian Fernandez-Pol, Sally Arai, Judith A Shizuru, Antonia MS Mueller, Gerlinde Wernig

Blood (2021) 138 (Supplement 1): 644.

DOI: https://doi.org/10.1182/blood-2021-151223

Published: 2021

Journal Articles

JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)

Blood (2021) 138 (Supplement 1): 554.

DOI: https://doi.org/10.1182/blood-2021-153074

Published: 2021

Journal Articles

Orca-T, a Precision Treg-Engineered Donor Product, Prevents Acute Gvhd with Less Immunosuppression in an Early Multicenter Experience with Myeloablative HLA-Matched Transplants

Blood (2020) 136 (Supplement 1): 47–48.

DOI: https://doi.org/10.1182/blood-2020-142974

Published: 2020

Journal Articles

Survival Following Post-HCT Relapse in Adult Acute Lymphoblastic Leukemia Has Improved in the Era of Novel Immunotherapies: A Single Institution Analysis

Juliana Craig, BA, Maria Iglesias, BS, Kristen Cunanan, PhD, Sally Arai, MD MS, Matthew J. Frank, MD PhD, Laura J. Johnston, MD, Robert Lowsky, MD FRCP, Everett H Meyer, MD PhD, David B. Miklos, MD PhD, Robert S. Negrin, MD, Andrew R. Rezvani, MD, Judith A Shizuru, MD PhD, Surbhi Sidana, MD, W-K Weng, MD PhD, Parveen Shiraz, MD, Lori S. Muffly, MD MS

Blood (2020) 136 (Supplement 1): 48–49.

DOI: https://doi.org/10.1182/blood-2020-141489

Published: 2020

Journal Articles

Outcomes after Autologous Stem Cell Transplant in Patients with Relapsed Multiple Myeloma

Christopher Lemieux, MD, Juliana Craig, BA, David Iberri, MD, Sally Arai, MD MS, Laura J. Johnston, MD, Robert Lowsky, MD FRCP, Lori S. Muffly, MD MS, Parveen Shiraz, MD, Michaela Liedtke, MD, Andrew R. Rezvani, MD, Matthew J. Frank, MD PhD, Wen-Kai Weng, MD PhD, Everett H Meyer, MD PhD, Judith A Shizuru, MD PhD, Robert S. Negrin, MD, David B. Miklos, MD PhD, Surbhi Sidana, MD

Blood (2020) 136 (Supplement 1): 11–12.

DOI: https://doi.org/10.1182/blood-2020-137091

Published: 2020

Journal Articles

5-Azacytidine Depletes Hematopoietic Stem Cells and Synergizes with an Anti-CD117 Antibody to Augment Engraftment of Donor Stem Cells in Immunocompetent Mice

Andriyana K Bankova, MD, Wendy W Pang, MD PhD, Brenda J Velasco, Janel R Long-Boyle, PharmD, PhD, Judith A Shizuru, MD PhD

Blood (2020) 136 (Supplement 1): 23–24.

DOI: https://doi.org/10.1182/blood-2020-139058

Published: 2020

Journal Articles

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Blood (2020) 136 (Supplement 1): 10.

DOI: https://doi.org/10.1182/blood-2020-137762

Published: 2020

Journal Articles

Bleeding and Thrombosis Are Associated with Endothelial Dysfunction in CAR-T Cell Therapy and Are Increased in Patients Experiencing Neurologic Toxicity

Blood (2020) 136 (Supplement 1): 32–33.

DOI: https://doi.org/10.1182/blood-2020-142218

Published: 2020

Journal Articles

Monitoring Measurable Residual Disease Using Peripheral Blood in Acute Lymphoblastic Leukemia: Results of a Prospective, Observational Study

Blood (2020) 136 (Supplement 1): 22–23.

DOI: https://doi.org/10.1182/blood-2020-138988

Published: 2020

Journal Articles

Outcomes after Second Allogeneic Transplantation and Donor Lymphocyte Infusion for Relapse after a First Allogeneic Transplant

Christopher Lemieux, MD, Lori S. Muffly, MD MS, Sally Arai, MD MS, Andrew R. Rezvani, MD, Surbhi Sidana, MD, Laura J. Johnston, MD, Wen-Kai Weng, MD PhD, Parveen Shiraz, MD, Matthew J. Frank, MD PhD, Everett H Meyer, MD PhD, Judith A Shizuru, MD PhD, David B. Miklos, MD PhD, Robert S. Negrin, MD, Robert Lowsky, MD FRCP

Blood (2020) 136 (Supplement 1): 22–23.

DOI: https://doi.org/10.1182/blood-2020-134250

Published: 2020

Journal Articles

Long-Term Outcomes of Patients with Peripheral T-Cell Lymphoma after Autologous Hematopoietic Cell Transplantation

Olivier Veilleux, MD, Francisco Socola, MD, Sally Arai, MD MS, Robert Lowsky, MD FRCP, Judith A Shizuru, MD PhD, Parveen Shiraz, MD, Lori S. Muffly, MD MS, Laura J. Johnston, MD, Matthew J. Frank, MD PhD, Surbhi Sidana, MD, Everett H Meyer, MD PhD, Andrew R. Rezvani, MD, David B. Miklos, MD PhD, Robert S. Negrin, MD, Wen-Kai Weng, MD PhD

Blood (2020) 136 (Supplement 1): 33–34.

DOI: https://doi.org/10.1182/blood-2020-136493

Published: 2020

Journal Articles

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Rajni Agarwal, MD, Christopher C. Dvorak, MD, Hye-Sook Kwon, PhD, Janel R Long-Boyle, PharmD, PhD, Susan S Prohaska, PhD MS, Janice W Brown, MD, Anne Le, Alyssa Guttman-Klein, Irving L Weissman, MD, Morton J Cowan, MD, Aaron C. Logan, MD PhD, Kenneth I. Weinberg, MD, Robertson Parkman, MD, Maria-Grazia Roncarolo, MD, Judith A Shizuru, MD PhD

Blood (2019) 134 (Supplement_1): 800.

DOI: https://doi.org/10.1182/blood-2019-126239

Published: 2019

Journal Articles

Improved Outcomes for Relapsed/Refractory Classic Hodgkin Lymphoma Following Autologous Stem Cell Transplantation in the Era of Novel Agents

R. Alejandro Sica, MD, Michael A Spinner, John S Tamaresis, PhD, Ranjana H Advani, MD, Laura J Johnston, MD, Robert Lowsky, MD, Everett H Meyer, MD PhD, David B Miklos, MD PhD, Lori S Muffly, MD, Andrew R Rezvani, MD, Judith A Shizuru, MD PhD, Wen-Kai Weng, MD PhD, Robert S. Negrin, MD, Sally Arai, MD

Blood (2019) 134 (Supplement_1): 2022.

DOI: https://doi.org/10.1182/blood-2019-131532

Published: 2019

Journal Articles

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Hye-Sook Kwon, Aaron C. Logan, Akanksha Chhabra, Wendy W. Pang, Agnieszka Czechowicz, Keri Tate, Alan Le, Jessica Poyser, Roger Hollis, Benjamin V. Kelly, Donald B. Kohn, Irving L. Weissman, Susan S. Prohaska, Judith A. Shizuru

Blood (2019) 133 (19): 2104–2108.

DOI: https://doi.org/10.1182/blood-2018-06-853879

Published: 2019

Includes: Supplemental data

Journal Articles

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Wendy W. Pang, Agnieszka Czechowicz, Aaron C. Logan, Rashmi Bhardwaj, Jessica Poyser, Christopher Y. Park, Irving L. Weissman, Judith A. Shizuru

Blood (2019) 133 (19): 2069–2078.

DOI: https://doi.org/10.1182/blood-2018-06-858159

Published: 2019

Includes: Supplemental data

Journal Articles

Elevated Axicabtagene Ciloleucel (CAR-19) Expansion By Immunophenotyping Is Associated with Toxicity in Diffuse Large B-Cell Lymphoma

Blood (2018) 132 (Supplement 1): 576.

DOI: https://doi.org/10.1182/blood-2018-99-113261

Published: 2018

Journal Articles

Nonmyeloablative Allogeneic Transplantation Using TLI-ATG Conditioning for Lymphoid and Myeloid Malignancies: Mature Follow-up from a Large, Single Institution Cohort

Michael A Spinner, MD, Vanessa E Kennedy, MD, John S Tamaresis, PhD, Philip W Lavori, PhD, Linda V Elder, BA, Sally Arai, MD, Laura J Johnston, MD, Everett H Meyer, MD PhD, David B. Miklos, MD PhD, Lori S Muffly, MD, Robert S. Negrin, MD, Andrew R Rezvani, MD, Judith A Shizuru, MD PhD, Wen-Kai Weng, MD PhD, Richard T Hoppe, MD, Samuel Strober, MD, Robert Lowsky, MD

Blood (2018) 132 (Supplement 1): 4638.

DOI: https://doi.org/10.1182/blood-2018-99-113597

Published: 2018

Journal Articles

Consolidative CD8 + Memory T-Cell Donor Lymphocyte Infusion Augments Donor Chimerism with a Low Risk of Gvhd Following Matched Related Donor Hematopoietic Cell Transplantation

Michael A. Spinner, MD, Lori S. Muffly, MD MS, Sally Arai, MD, Laura Johnston, MD, Everett H. Meyer, MD PhD, David B. Miklos, MD PhD, Robert S. Negrin, MD, Andrew R. Rezvani, MD, Judith A. Shizuru, MD PhD, Wen-Kai Weng, MD PhD, Samuel Strober, MD, Robert Lowsky, MD

Blood (2017) 130 (Supplement 1): 2003.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2003.2003

Published: 2017

2 3 4

NARROW

Anti-CD117 CAR T Cells Incorporating a Safety Switch Eradicate Acute Myeloid Leukemia and Deplete Human Hematopoietic Stem Cells

Mgta-145 + Plerixafor Provides GCSF-Free Rapid and Reliable Hematopoietic Stem Cell Mobilization for Autologous Stem Cell Transplant in Patients with Multiple Myeloma: A Phase 2 Study

Selective Targeting of Immune Modulatory Proteins to Mitigate Fibrosis and Inflammation in Sclerodermatous Graft-Vs-Host Disease

JSP191 As a Single-Agent Conditioning Regimen Results in Successful Engraftment, Donor Myeloid Chimerism, and Production of Donor Derived Naïve Lymphocytes in Patients with Severe Combined Immunodeficiency (SCID)

Orca-T, a Precision Treg-Engineered Donor Product, Prevents Acute Gvhd with Less Immunosuppression in an Early Multicenter Experience with Myeloablative HLA-Matched Transplants

Survival Following Post-HCT Relapse in Adult Acute Lymphoblastic Leukemia Has Improved in the Era of Novel Immunotherapies: A Single Institution Analysis

Outcomes after Autologous Stem Cell Transplant in Patients with Relapsed Multiple Myeloma

5-Azacytidine Depletes Hematopoietic Stem Cells and Synergizes with an Anti-CD117 Antibody to Augment Engraftment of Donor Stem Cells in Immunocompetent Mice

First Report of Non-Genotoxic Conditioning with JSP191 (anti-CD117) and Hematopoietic Stem Cell Transplantation in a Newly Diagnosed Patient with Severe Combined Immune Deficiency

Bleeding and Thrombosis Are Associated with Endothelial Dysfunction in CAR-T Cell Therapy and Are Increased in Patients Experiencing Neurologic Toxicity

Monitoring Measurable Residual Disease Using Peripheral Blood in Acute Lymphoblastic Leukemia: Results of a Prospective, Observational Study

Outcomes after Second Allogeneic Transplantation and Donor Lymphocyte Infusion for Relapse after a First Allogeneic Transplant

Long-Term Outcomes of Patients with Peripheral T-Cell Lymphoma after Autologous Hematopoietic Cell Transplantation

Non-Genotoxic Anti-CD117 Antibody Conditioning Results in Successful Hematopoietic Stem Cell Engraftment in Patients with Severe Combined Immunodeficiency

Improved Outcomes for Relapsed/Refractory Classic Hodgkin Lymphoma Following Autologous Stem Cell Transplantation in the Era of Novel Agents

Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice

Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice

Elevated Axicabtagene Ciloleucel (CAR-19) Expansion By Immunophenotyping Is Associated with Toxicity in Diffuse Large B-Cell Lymphoma

Nonmyeloablative Allogeneic Transplantation Using TLI-ATG Conditioning for Lymphoid and Myeloid Malignancies: Mature Follow-up from a Large, Single Institution Cohort

Consolidative CD8 + Memory T-Cell Donor Lymphocyte Infusion Augments Donor Chimerism with a Low Risk of Gvhd Following Matched Related Donor Hematopoietic Cell Transplantation

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American Society of Hematology

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American Society of Hematology

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