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Joseph H. Antin
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Journal Articles

BET-bromodomain and EZH2 inhibitor–treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes

Michael C. Zaiken, Ryan Flynn, Katelyn G. Paz, Stephanie Y. Rhee, Sujeong Jin, Fathima A. Mohamed, Asim Saha, Govindarajan Thangavelu, Paul M. C. Park, Matthew L. Hemming, Peter T. Sage, Arlene H. Sharpe, Michel DuPage, Jeffrey A. Bluestone, Angela Panoskaltsis-Mortari, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Leo Luznik, Ivan Maillard, Geoffrey R. Hill, Kelli P. A. MacDonald, David H. Munn, Jonathan S. Serody, William J. Murphy, Leslie S. Kean, Yi Zhang, James E. Bradner, Jun Qi, Bruce R. Blazar
Journal: Blood
Blood (2022) 139 (19): 2983–2997.
DOI: https://doi.org/10.1182/blood.2021014557
Published: 2022
Includes: Supplemental data
Journal Articles

Phase II Clinical Trial of Abatacept for Steroid-Refractory Chronic Graft Versus Host Disease

Anita G. Koshy, Haesook T. Kim, Dina Stroopinsky, Jessica J. Liegel, Jon E. Arnason, Vincent T. Ho, Joseph H. Antin, Robin M. Joyce, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Emma K. Logan, Pavania Elavalakanar, Susan Stephenson, Hassan El Banna, Poorva Bindal, Giulia Cheloni, David Avigan, Robert J. Soiffer, Jacalyn Rosenblatt
Journal: Blood
Blood (2021) 138 (Supplement 1): 264.
DOI: https://doi.org/10.1182/blood-2021-148343
Published: 2021
Journal Articles

The clinical and functional effects of TERT variants in myelodysplastic syndrome

Christopher R. Reilly, Mikko Myllymäki, Robert Redd, Shilpa Padmanaban, Druha Karunakaran, Valerie Tesmer, Frederick D. Tsai, Christopher J. Gibson, Huma Q. Rana, Liang Zhong, Wael Saber, Stephen R. Spellman, Zhen-Huan Hu, Esther H. Orr, Maxine M. Chen, Immaculata De Vivo, Daniel J. DeAngelo, Corey Cutler, Joseph H. Antin, Donna Neuberg, Judy E. Garber, Jayakrishnan Nandakumar, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2021) 138 (10): 898–911.
DOI: https://doi.org/10.1182/blood.2021011075
Published: 2021
Includes: Supplemental data
Journal Articles

HLA-haploidentical vs matched unrelated donor transplants with posttransplant cyclophosphamide-based prophylaxis

Mahasweta Gooptu, Rizwan Romee, Andrew St. Martin, Mukta Arora, Monzr Al Malki, Joseph H. Antin, Christopher N. Bredeson, Claudio G. Brunstein, Saurabh Chhabra, Ephraim J. Fuchs, Nilanjan Ghosh, Michael R. Grunwald, Christopher G. Kanakry, Natasha Kekre, Jospeh P. McGuirk, Ian K. McNiece, Rohtesh S. Mehta, Marco Mielcarek, Fillipo Milano, Dipenkumar Modi, Ran Reshef, Scott R. Solomon, Mark A. Schroeder, Edmund K. Waller, Yoshiro Inamoto, Robert J. Soiffer, Mary Eapen
Journal: Blood
Blood (2021) 138 (3): 273–282.
DOI: https://doi.org/10.1182/blood.2021011281
Published: 2021
Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Clinical Trials & Observations Brief Report
Livius Penter, Yi Zhang, Alexandra Savell, Teddy Huang, Nicoletta Cieri, Emily M. Thrash, Seunghee Kim-Schulze, Aashna Jhaveri, Jingxin Fu, Srinika Ranasinghe, Shuqiang Li, Wandi Zhang, Emma S. Hathaway, Matthew Nazzaro, Haesook T. Kim, Helen Chen, Magdalena Thurin, Scott J. Rodig, Mariano Severgnini, Carrie Cibulskis, Stacey Gabriel, Kenneth J. Livak, Corey Cutler, Joseph H. Antin, Sarah Nikiforow, John Koreth, Vincent T. Ho, Philippe Armand, Jerome Ritz, Howard Streicher, Donna Neuberg, F. Stephen Hodi, Sacha Gnjatic, Robert J. Soiffer, X. Shirley Liu, Matthew S. Davids, Pavan Bachireddy, Catherine J. Wu
Journal: Blood
Blood (2021) 137 (23): 3212–3217.
DOI: https://doi.org/10.1182/blood.2021010867
Published: 2021
Includes: Supplemental data
Journal Articles

Double unrelated umbilical cord blood vs HLA-haploidentical bone marrow transplantation: the BMT CTN 1101 trial

Clinical Trials & Observations
Ephraim J. Fuchs, Paul V. O’Donnell, Mary Eapen, Brent Logan, Joseph H. Antin, Peter Dawson, Steven Devine, Mary M. Horowitz, Mitchell E. Horwitz, Chatchada Karanes, Eric Leifer, John M. Magenau, Joseph P. McGuirk, Lawrence E. Morris, Andrew R. Rezvani, Richard J. Jones, Claudio G. Brunstein
Journal: Blood
Blood (2021) 137 (3): 420–428.
DOI: https://doi.org/10.1182/blood.2020007535
Published: 2021
Includes: Supplemental data
Journal Articles

Short telomere length predicts nonrelapse mortality after stem cell transplantation for myelodysplastic syndrome

Clinical Trials & Observations
Mikko Myllymäki, Robert Redd, Christopher R. Reilly, Wael Saber, Stephen R. Spellman, Christopher J. Gibson, Zhen-Huan Hu, Tao Wang, Esther H. Orr, Jaclyn G. Grenier, Maxine M. Chen, David P. Steensma, Corey Cutler, Immaculata De Vivo, Joseph H. Antin, Donna Neuberg, Suneet Agarwal, R. Coleman Lindsley
Journal: Blood
Blood (2020) 136 (26): 3070–3081.
DOI: https://doi.org/10.1182/blood.2020005397
Published: 2020
Includes: Supplemental data
Journal Articles

Safety and Efficacy of Adding Venetoclax to Reduced Intensity Conditioning Chemotherapy Prior to Allogeneic Hematopoietic Cell Transplantation in Patients with High Risk Myeloid Malignancies

Jacqueline S. Garcia, MD, Haesook Kim, Corey Cutler, MD MPH, FRCPC, Eric S. Winer, MD, Richard M. Stone, MD, Vincent T. Ho, MD, Rizwan Romee, MD, John Koreth, MBBS, DPhil, Mahasweta Gooptu, MD, Sarah Nikiforow, MD PhD, Roman M Shapiro, MD, David P. Steensma, MD, Marlise R. Luskin, MD, Martha Wadleigh, MD, Fiona Loschi, Jeremy Ryan, Anthony Letai, R. Coleman Lindsley, MD PhD, Jennifer Brock, Robert J. Soiffer, MD, Daniel J. DeAngelo, MD PhD, Joseph H. Antin, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–39.
DOI: https://doi.org/10.1182/blood-2020-134947
Published: 2020
Journal Articles

Early Reconstitution of CD6+ T Cells after Hematopoietic Cell Transplantation Identifies a Suitable Target for Acute Graft Versus Host Disease Treatment Using Anti-CD6 Monoclonal Antibody Itolizumab

Benedetta Rambaldi, MD, Haesook T. Kim, PhD, Carol Reynolds, PhD, Sharmila Chamling Rai, BSc, Takeru Asano, MD PhD, Yohei Arihara, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Joseph H. Antin, MD, Rizwan Romee, MD, Robert J. Soiffer, MD, Jeanette Ampudia, Cherie Tracy Ng, PhD MPH, Stephen Connelly, PhD MBA, Jerome Ritz, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 10–11.
DOI: https://doi.org/10.1182/blood-2020-138710
Published: 2020
Journal Articles

Cytokine-Induced Memory-like NK Cells Exhibit Massive Expansion and Long-Term Persistence after Infusion Post-Haploidentical Stem Cell Transplantation: A Report of the First Three Cases in a Phase I Trial

Roman M Shapiro, MD, Sarah Nikiforow, MD PhD, Benedetta Rambaldi, MD, Juliana Vergara, Heather Daley, Haesook T. Kim, PhD, Corey Cutler, MD MPH, FRCPC, Vincent T. Ho, MD, John Koreth, MBBS, DPhil, Mahasweta Gooptu, MD, Joseph H. Antin, MD, Jennifer Brock, Catherine J. Wu, MD, Robert J. Soiffer, MD, Jerome Ritz, MD, Rizwan Romee, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
DOI: https://doi.org/10.1182/blood-2020-133933
Published: 2020
Journal Articles

Defibrotide: Real World Experience for Management of Veno-Occlusive Disease/ Sinusoidal Obstructive Syndrome after Hematopoietic Stem Cell Transplantation

Mary Nauffal, MS,PharmD, Haesook T. Kim, PhD, Paul G. Richardson, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Roman M Shapiro, MD, Rizwan Romee, MD, Vincent T. Ho, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 23–24.
DOI: https://doi.org/10.1182/blood-2020-135895
Published: 2020
Journal Articles

Comparison of Outcomes after Haploidentical Relative and HLA Matched Unrelated Donor Transplantation with Post-Transplant Cyclophosphamide Containing Gvhd Prophylaxis Regimens

Mahasweta Gooptu, MD, Andrew St. Martin, MS, Rizwan Romee, MD, Mukta Arora, MD, Monzr M. Al Malki, MD, Joseph H. Antin, MD, Christopher Bredeson, MDFRCPC,MSc, Claudio G. Brunstein, MD PhD, Saurabh Chhabra, MD, Ephraim J. Fuchs, MD MBA, Nilanjan Ghosh, MD PhD, Michael R. Grunwald, MD, Yoshihiro Inamoto, MD, Christopher G. Kanakry, MD, Natasha Kekre, MD MPH, FRCPC, Joseph P. McGuirk, DO, Ian K. McNiece, PhD, Rohtesh S. Mehta, MDMPH,MS, Marco Last Mielcarek, MD, Filipo Milano, MD PhD, Dipenkumar Modi, MD, Ran Reshef, MD, Mark A. Schroeder, MD, Robert J. Soiffer, MD, Scott R. Solomon, MD, Edmund K. Waller, PhDMD, Mary Eapen, MBBS, MS
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
DOI: https://doi.org/10.1182/blood-2020-137221
Published: 2020
Journal Articles

Impact of IL-6R Blockade for Cytokine Release Syndrome in Haploidentical Donor Stem Cell Transplant Patients on Infections, Clinical Outcomes and Immune Reconstitution

Katherine P Baker, MD, Roman M Shapiro, MD, Carol Reynolds, PhD, Benedetta Rambaldi, MD, Augustine Weber, Matilde Dal Boni, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Joseph H. Antin, MD, Vincent T. Ho, MD, Sarah Nikiforow, MD PhD, Mahasweta Gooptu, MD, Catherine J. Wu, MD, Robert J. Soiffer, MD, Jerome Ritz, MD, Rizwan Romee, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
DOI: https://doi.org/10.1182/blood-2020-136390
Published: 2020
Journal Articles

Outcomes of IDH1 - and IDH2 -Mutated AML Patients Undergoing Allogeneic Hematopoietic Cell Transplantation

Evan C. Chen, MD, Shuli Li, PhD, Ann-Kathrin Eisfeld, MD, Marlise R Luskin, MDMS, Alice S. Mims, MD, Daniel Jones, MD PhD, Joseph H. Antin, MD, Corey Cutler, MD MPH, FRCPC, John Koreth, MBBS, DPhil, Vincent T. Ho, MD, Mahasweta Gooptu, MD, Rizwan Romee, MD, Areej El-Jawahri, MD, Steven L. McAfee, MD, Zachariah Defilipp, MD, Robert J. Soiffer, MD, Yi-Bin Chen, MD, Amir T. Fathi
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
DOI: https://doi.org/10.1182/blood-2020-140353
Published: 2020
Journal Articles

Randomized multicenter trial of sirolimus vs prednisone as initial therapy for standard-risk acute GVHD: the BMT CTN 1501 trial

Clinical Trials & Observations
Joseph Pidala, Mehdi Hamadani, Peter Dawson, Michael Martens, Amin M. Alousi, Madan Jagasia, Yvonne A. Efebera, Saurabh Chhabra, Iskra Pusic, Shernan G. Holtan, James L. M. Ferrara, John E. Levine, Marco Mielcarek, Claudio Anasetti, Joseph H. Antin, Javier Bolaños-Meade, Alan Howard, Brent R. Logan, Eric S. Leifer, Theresa S. Pritchard, Mary M. Horowitz, Margaret L. MacMillan
Journal: Blood
Blood (2020) 135 (2): 97–107.
DOI: https://doi.org/10.1182/blood.2019003125
Published: 2020
Includes: Supplemental data
Journal Articles

Inhibition of inositol kinase B controls acute and chronic graft-versus-host disease

Govindarajan Thangavelu, Jing Du, Katelyn G. Paz, Michael Loschi, Michael C. Zaiken, Ryan Flynn, Patricia A. Taylor, Andrew Kemal Kirchmeier, Angela Panoskaltsis-Mortari, Leo Luznik, Kelli P. MacDonald, Geoffrey R. Hill, Ivan Maillard, David H. Munn, Jonathan S. Serody, William J. Murphy, David Miklos, Corey S. Cutler, John Koreth, Joseph H. Antin, Robert J. Soiffer, Jerome Ritz, Carol Dahlberg, Andrew T. Miller, Bruce R. Blazar
Journal: Blood
Blood (2020) 135 (1): 28–40.
DOI: https://doi.org/10.1182/blood.2019000032
Published: 2020
Includes: Supplemental data
Journal Articles

Improved Outcomes with Cyclophosphamide/Total Body Irradiation 14 Gy Compared to Cyclophosphamide/Total Body Irradiation 12 Gy in Patients with Acute Lymphoblastic Leukemia Undergoing Myeloablative Allogeneic Transplantation

Cindy Lynn Hickey, MDFRCPC, Haesook T. Kim, PhD, Vincent T. Ho, MD, Sarah Nikiforow, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Jerome Ritz, MD, Rizwan Romee, MD PhD, Edwin P. Alyea, III, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Corey Cutler, MD MPH, FRCPC
Journal: Blood
Blood (2019) 134 (Supplement_1): 263.
DOI: https://doi.org/10.1182/blood-2019-122257
Published: 2019
Journal Articles

Graft Failure after Haploidentical Hematopoietic Stem Cell Transplantation

Cindy Lynn Hickey, MDFRCPC, Haesook T. Kim, PhD, Sarah Nikiforow, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Jerome Ritz, MD, Vincent T. Ho, MD, Edwin P. Alyea, III, MD, Robert J. Soiffer, MD, Joseph H. Antin, MD, Corey Cutler, MD MPH, FRCPC, Rizwan Romee, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4486.
DOI: https://doi.org/10.1182/blood-2019-121659
Published: 2019
Journal Articles

Anti-CD6 Monoclonal Antibody Itolizumab Efficiently Inhibits T Cell Proliferation after in Vitro TCR Stimulation in the Setting of Acute Graft Versus Host Disease

Benedetta Rambaldi, MD, Carol Reynolds, PhD, Sharmila Chamling Rai, BSc, Takeru Asano, MD PhD, Yohei Arihara, MD PhD, Mahasweta Gooptu, MD, John Koreth, MBBS, DPhil, Corey Cutler, MD MPH, FRCPC, Sarah Nikiforow, MD PhD, Vincent T. Ho, MD, Edwin P. Alyea, III, MD, Joseph H. Antin, MD, Rizwan Romee, MD PhD, Robert J. Soiffer, MD, Domenico Russo, MD, Jeanette Ampudia, BSc, Cherie Tracy Ng, PhD MPH, Stephen Connelly, PhD MBA, Jerome Ritz, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4517.
DOI: https://doi.org/10.1182/blood-2019-125721
Published: 2019
Journal Articles

Development of HHV-6-Specific Immunity after Cord Blood Transplantation in Adults Depends on Reconstitution of Thymopoiesis and Regeneration of CD4 + T Cells

Natalia M Tijaro-Ovalle, MD, Shuli Li, PhD, Zachariah Defilipp, MD, Ioannis Politikos, MD, Robin M. Joyce, MD, Philippe Armand, MD PhD, Vincent T. Ho, John Koreth, MBBS, DPhil, Sarah Nikiforow, MD PhD, Edwin P. Alyea, III, MD, David E. Avigan, MD, Jacalyn Rosenblatt, MD, Jami Brown, MS, Steven McAfee, MD, Bimalangshu Dey, MD, Areej El-Jawahri, MD, Thomas Spitzer, MD, Yi-Bin Chen, Robert J. Soiffer, MD, Joseph H. Antin, MD, Karen K. Ballen, MD, Corey S. Cutler, MD MPH, FRCPC, Jerome Ritz, MD, Vassiliki A Boussiotis, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3275.
DOI: https://doi.org/10.1182/blood-2019-129154
Published: 2019