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Journal Articles

Glucarpidase for Treatment of High-Dose Methotrexate Toxicity

Shruti Gupta, Sarah Allison Kaunfer, Kevin L Chen, Julie-Alexia Dias, Anitha Vijayan, Arun Rajasekaran, Jason Prosek, Huong L. Truong, Anthony Wood, Claude Bassil, Amanda DeMauro Renaghan, Chintan V Shah, Jingjing Zhang, Ilya Glezerman, Christopher Carlos, Katherine Kelly, Christopher J Passero, Jan Drappatz, Ala Abudayyeh, Daniel Shin, C. John Sperati, Bradley J Yelvington, Swetha Rani Kanduri, Javier A Neyra, Daniel Edmonston, Anushree C Shirali, Anip Bansal, Abdallah Geara, Zain Mithani, Susan L Ziolkowski, Arash Rashidi, Jonathan Jakubowski, Ashwini Pujari, David A Bond, Emily K Dotson, Sarah A Wall, John T. Patton, Jason N Barreto, Sandra M Hermann, Mohammad Salman Sheikh, Rachid C Baz, Jae Hui Lee, Nicholas Lucchesi, Michael Kolman, Muhammad Ahsan Rasheed, Afsheen Afzal, Dasol Kang, Amrita Mahesh, Raymond Hsu, Anthony Nicolaysen, Kibrewessen Tefera, Claire Schretlen, Ryan M Miller, Juan Carlos Q Velez, Alexander H Flannery, Abinet M Aklilu, Shuchi Anand, Soniya Chandrasekhara, Vicki Donley, Ashka Patel, Jian Ni, Shobana Krishnamurthy, Rafia Ali, Osman A Yilmam, Sophia L Wells, Jessica L Ortega, Olivia L Green-Lingren, Rebecca Karp Leaf, Meghan E Sise, Lakshmi Nayak, Ann S. LaCasce, Nelson Leung, David E Leaf

Blood blood.2024026211.

https://doi.org/10.1182/blood.2024026211

Published: 2025

Includes: Supplemental data

Journal Articles

Venetoclax Plus Azacitidine for Newly Diagnosed Younger Acute Myeloid Leukemia Patients Independent of Fitness for Intensive Chemotherapy

Blood (2024) 144 (Supplement 1): 969.

https://doi.org/10.1182/blood-2024-199267

Published: 2024

Journal Articles

SAGES1: Clinical Translation of CRISPR Genome Editing Strategy to Induce Fetal Hemoglobin to Treat Sickle Cell Disease

Blood (2024) 144 (Supplement 1): 146.

https://doi.org/10.1182/blood-2024-211182

Published: 2024

Journal Articles

Remarkable Molecular Response in Patients with Polycythemia Vera Treated with Ropeginterferon Alfa-2b

Blood (2024) 144 (Supplement 1): 4562.

https://doi.org/10.1182/blood-2024-203148

Published: 2024

Journal Articles

Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin

Alfonso G. Fernandez, Georgios E. Christakopoulos, Dudley E. Michael, Razan B. A. Sweileh, Rahul Telange, Heather Sheppard, Yu Yao, Jingjing Zhang, Vania Manolova, Elizabeta Nemeth, Tomas Ganz, Mitchell J. Weiss

Blood (2023) 142 (Supplement 1): 558.

https://doi.org/10.1182/blood-2023-185008

Published: 2023

Journal Articles

NR2F1 : A Novel Candidate for Gamma Globin Activation

Ruiqiong Wu, Siqi Yi, Yichao Li, Dewan Shrestha, Minzhang Zheng, Jingjing Zhang, Yong Cheng

Blood (2023) 142 (Supplement 1): 1106.

https://doi.org/10.1182/blood-2023-190312

Published: 2023

Journal Articles

Study on the Changes of Immune Cells in the Evolution of Myelodysplastic Syndromes

Jing Wang, Xiaoyuan Zhang, Yue Zhao, Jingjing Zhang, Yibin Zhou, Li Hou

Blood (2023) 142 (Supplement 1): 5381.

https://doi.org/10.1182/blood-2023-179797

Published: 2023

Journal Articles

Loss of miR-144/451 alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin

Julia Keith, Georgios E. Christakopoulos, Alfonso G. Fernandez, Yu Yao, Jingjing Zhang, Kalin Mayberry, Rahul Telange, Razan B. A. Sweileh, Michael Dudley, Camilla Westbrook, Heather Sheppard, Mitchell J. Weiss, Christophe Lechauve

Blood (2023) 142 (10): 918–932.

https://doi.org/10.1182/blood.2022017265

Published: 2023

Includes: Supplemental data

Journal Articles

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Blood (2022) 140 (Supplement 1): 7784–7785.

https://doi.org/10.1182/blood-2022-162639

Published: 2022

Journal Articles

Phase Ⅱ,Open-Label, Multicenter, Single-Arm Study Investigating the Efficacy and Safety of Ropeginterferon Alfa-2b in Chinese Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea(HU)

Blood (2022) 140 (Supplement 1): 6858–6859.

https://doi.org/10.1182/blood-2022-165789

Published: 2022

Journal Articles

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

Ruopeng Feng, Thiyagaraj Mayuranathan, Peng Huang, Phillip A Doerfler, Yichao Li, Yu Yao, Jingjing Zhang, Lance E. Palmer, Peng Xu, Kalin Mayberry, Shaela Wright, Chunliang Li, Yong Cheng, Gerd A. Blobel, M. Celeste Simon, Mitchell J. Weiss

Blood (2021) 138 (Supplement 1): 574.

https://doi.org/10.1182/blood-2021-149901

Published: 2021

Journal Articles

The Design of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Chinese Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea (HU)

Jie Jin, Lei Zhang, Su-Jiang Zhang, Suning Chen, Ming-hui Duan, Jingjing Zhang, Wei Wang, Warren Shen, Oleh Zagrijtschuk, Raymond Urbanski, Albert Qin, Zhijian Xiao

Blood (2021) 138 (Supplement 1): 4628.

https://doi.org/10.1182/blood-2021-146449

Published: 2021

Journal Articles

Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling

Thiyagaraj Mayuranathan, Jonathan S. Yen, PhD, Gregory A. Newby, PhD, Yu Yao, MD, Shaina N. Porter, PhD, Kaitly J. Woodard, BS, Jingjing Zhang, MS, Kalin Mayberry, BS, Akshay Sharma, MBBS, Shondra M. preutt-Miller, PhD, John F. Tisdale, MD, Shengdar Q. Tsai, PhD, David R. Liu, PhD, Mitchell J. Weiss, MD PhD

Blood (2020) 136 (Supplement 1): 21–22.

https://doi.org/10.1182/blood-2020-141498

Published: 2020

Journal Articles

Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells

Jonathan S Yen, PhD, Gregory A. Newby, PhD, Thiyagaraj Mayuranathan, Shaina N. Porter, PhD, Yu Yao, MD, Kaitly J. Woodard, BS, Kalin Mayberry, BS, Kelcee Everette, Jingjing Zhang, MS, Jordana M Henderson, MS, Anton P Mccaffrey, Jonathan Yen, John F. Tisdale, MD, Shengdar Q. Tsai, PhD, David R. Liu, PhD, Mitchell J. Weiss, MD PhD

Blood (2020) 136 (Supplement 1): 13–14.

https://doi.org/10.1182/blood-2020-139016

Published: 2020

Journal Articles

Activation of ULK1 Kinase Mediates Clearance of Free Alpha-Globin in Human Beta-Thalassemic Erythroblasts

Christophe Lechauve, PhD, Julia Keith, Eugene Khandros, MD PhD, Stephanie Fowler, Kalin Mayberry, Abdullah Freiwan, Christopher Thom, MD PhD, Jingjing Zhang, Heather Tillman, DVM, PhD, Mondira Kundu, MD PhD, Irene Motta, MD, Maria Domenica Cappellini, MD, Mitchell J. Weiss, MD PhD

Blood (2018) 132 (Supplement 1): 411.

https://doi.org/10.1182/blood-2018-99-113901

Published: 2018

NARROW

Glucarpidase for Treatment of High-Dose Methotrexate Toxicity

Venetoclax Plus Azacitidine for Newly Diagnosed Younger Acute Myeloid Leukemia Patients Independent of Fitness for Intensive Chemotherapy

SAGES1: Clinical Translation of CRISPR Genome Editing Strategy to Induce Fetal Hemoglobin to Treat Sickle Cell Disease

Remarkable Molecular Response in Patients with Polycythemia Vera Treated with Ropeginterferon Alfa-2b

Iron Restriction Alleviates β-Thalassemia By Stimulating ULK1-Mediated Autophagy of Free α-Globin

NR2F1 : A Novel Candidate for Gamma Globin Activation

Study on the Changes of Immune Cells in the Evolution of Myelodysplastic Syndromes

Loss of miR-144/451 alleviates β-thalassemia by stimulating ULK1-mediated autophagy of free α-globin

Increased Potency and Uniformity of Fetal Hemoglobin Induction from Base Editing Compared to Cas9 Nuclease

Phase Ⅱ,Open-Label, Multicenter, Single-Arm Study Investigating the Efficacy and Safety of Ropeginterferon Alfa-2b in Chinese Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea(HU)

Regulation of Fetal Hemoglobin Expression By the VHL-HIF1α Oxygen Sensing System

The Design of a Phase 2 Study to Evaluate the Safety and Efficacy of Ropeginterferon Alfa-2b (P1101) in Chinese Patients with Polycythemia Vera Resistant or Intolerant to Hydroxyurea (HU)

Adenosine Base Editing of γ-Globin Promoters Induces Fetal Hemoglobin and Inhibit Erythroid Sickling

Base Editing Eliminates the Sickle Cell Mutation and Pathology in Hematopoietic Stem Cells Derived Erythroid Cells

Activation of ULK1 Kinase Mediates Clearance of Free Alpha-Globin in Human Beta-Thalassemic Erythroblasts

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American Society of Hematology

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American Society of Hematology

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