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Jeffrey E. Rubnitz
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Journal Articles

Outcomes in patients with ETV6 :: RUNX1 or high-hyperdiploid B-ALL treated in the St. Jude Total Therapy XV/XVI studies

Clinical Trials & Observations
Katelyn Purvis, Yinmei Zhou, Seth E. Karol, Jeffrey E. Rubnitz, Raul C. Ribeiro, Shawn Lee, Jun J. Yang, W. Paul Bowman, Lu Wang, Stephanie B. Dixon, Kathryn G. Roberts, Qingsong Gao, Cheng Cheng, Charles G. Mullighan, Sima Jeha, Ching-Hon Pui, Hiroto Inaba
Journal: Blood
Blood (2025) 145 (2): 190–201.
https://doi.org/10.1182/blood.2024024936
Published: 2025
Includes: Supplemental data
Journal Articles

Rapid Long-Read Epigenomic Diagnosis and Prognosis of Acute Myeloid Leukemia

Francisco Marchi, Ann-Kathrin Schade, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Jeffery M Klco, Alan S Gamis, Rhonda E. Ries, Anders Kolb, Richard Aplenc, Todd A. Alonzo, Stanley Pounds, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 103.
https://doi.org/10.1182/blood-2024-207665
Published: 2024
Journal Articles

CD123-CAR T Cells Manufactured in the Presence of Dasatinib Induce High Grade CRS and/or IEC-HS without Improving Efficacy in Pediatric Patients with Recurrent/Refractory Leukemia

Swati Naik, Madden Renee, Aimee C. Talleur, Rebecca Epperly, Timothy Lockey, Jennyfer Bran, Liqing Tian, Ying Li, Dinesh Keerthi, Alexandra Boyd, Amanda Lipsitt, Jeffrey E. Rubnitz, Jeffery M Klco, Barry Shulkin, Sarah Schell, Polly Adams, Jeoungeun John Park, Janice Riberdy, Na Shang, Jaquelyn T. Zoine, Raghuvaran Shanmugam, Chris Nevitt, Unmesha Thanekar, Jennifer Wallace, Elaine Harstead, Scott Perry, Catherine Willis, Jean-Yves Metais, Deanna M. Langfitt, Sheng Zhou, Salem M. Akel, Caitlin Zebley, Jeremy Chase Crawford, Benjamin Youngblood, Paul G. Thomas, Frank Fazio, Brandon M Triplett, Stephen Gottschalk, Mireya Paulina Velasquez
Journal: Blood
Blood (2024) 144 (Supplement 1): 2076.
https://doi.org/10.1182/blood-2024-208795
Published: 2024
Journal Articles

Oncogenic Potential and Sensitivity to Menin Inhibitors of a Novel Fusion KAT6B::NUTM2B in Congenital Myeloid Sarcoma with Bone Marrow Involvement

Rebecca Voss, Wenqing Qi, Yen-Chun Liu, Jing Ma, La'Ron Browne, Mahsa Khanlari, Juan M Barajas, Melvin Thomas, III, Victor B Pastor Loyola, Hui Cao, Seth E. Karol, Jeffrey E. Rubnitz, Jeffery M Klco, Lu Wang
Journal: Blood
Blood (2024) 144 (Supplement 1): 1352.
https://doi.org/10.1182/blood-2024-208358
Published: 2024
Journal Articles

Genome-Wide Association Study of Metabolites in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia Identified Novel Metabolite Quantitative Trait Loci

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 4327.
https://doi.org/10.1182/blood-2024-193819
Published: 2024
Journal Articles

Genome-Wide Association Study Identifies Variants Predictive of Febrile Neutropenia during Induction I in Newly Diagnosed Pediatric Acute Myeloid Leukemia Patients

Satyavardhan Rao Nittu, Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2024) 144 (Supplement 1): 6110.
https://doi.org/10.1182/blood-2024-208130
Published: 2024
Journal Articles

Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors

Juan M. Barajas, Milad Rasouli, Masayuki Umeda, Ryan Hiltenbrand, Sherif Abdelhamed, Rebecca Mohnani, Bright Arthur, Tamara Westover, Melvin E. Thomas, III, Minoo Ashtiani, Laura J. Janke, Beisi Xu, Ti-Cheng Chang, Wojciech Rosikiewicz, Emily Xiong, Chandra Rolle, Jonathan Low, Reethu Krishan, Guangchun Song, Michael P. Walsh, Jing Ma, Jeffrey E. Rubnitz, Ilaria Iacobucci, Taosheng Chen, Anja Krippner-Heidenreich, Christian M. Zwaan, Olaf Heidenreich, Jeffery M. Klco
Journal: Blood
Blood (2024) 143 (7): 619–630.
https://doi.org/10.1182/blood.2023021359
Published: 2024
Includes: Supplemental data
Journal Articles

The Methylome Atlas of Acute Leukemia Enables Novel Clinical Diagnostic Tool for AML

Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 121.
https://doi.org/10.1182/blood-2023-186894
Published: 2023
Journal Articles

Leveraging Custom CRISPR/Cas9 Screens to Identify AraC-Daunorubicin-Etoposide (ADE), Gemtuzumab Ozogamicin (GO), and Bortezomib Response Modulators Association with Clinical Outcomes in Pediatric AML

Nam Nguyen, Phani Krishna Parcha, Abderrahmane Tagmount, Bailey Gregory, Jeffrey E. Rubnitz, Raul C. Ribeiro, Xueyuan Cao, Todd A. Alonzo, Richard Aplenc, Alan S Gamis, Todd Cooper, E. Anders Kolb, Soheil Meshinchi, Stanley Pounds, Christopher Vulpe, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 1558.
https://doi.org/10.1182/blood-2023-178832
Published: 2023
Journal Articles

Intensification of Therapy and Pharmacogenetic Personalization Mitigate Racial Disparities in Pediatric Acute Myeloid Leukemia Outcomes

Jatinder K. Lamba, Richard J Marrero, Huiyun Wu, Xueyuan Cao, Phani Krishna Parcha, Seth E. Karol, Hiroto Inaba, Dennis John Kuo, Barbara Degar, Kenneth Matthew Heym, Jeffrey Taub, Norman J. Lacayo, Ching-Hon Pui, Raul C. Ribeiro, Stanley Pounds, Jeffrey E. Rubnitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 386.
https://doi.org/10.1182/blood-2023-173617
Published: 2023
Journal Articles

Relapse-Enriched Gene Expression Signature of Prognostic Relevance in Pediatric Acute Myeloid Leukemia

Satyavardhan Rao Nittu, Francisco Marchi, Nam Nguyen, Vivek M. Shastri, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Jeffery Klco, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2926.
https://doi.org/10.1182/blood-2023-189029
Published: 2023
Journal Articles

Results from the Phase 1 Portion of a Trial of Oral Ixazomib Combined with Chemotherapy in Relapsed/Refractory Acute Lymphoblastic Leukemia or Lymphoma in Children, Adolescents and Young Adults: A Report from the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium

Eric S. Schafer, Yueh-Yun Chi, Jemily Malvar, Teresa Rushing, Andrew Doan, Holly L. Pacenta, Reuven J. Schore, Richard Sposto, Roy Leong, Paul S. Gaynon, Jeffrey E. Rubnitz, Julio C. Barredo, Tamra Slone, Melinda Pauly, Alan S. Wayne, Deepa Bhojwani, Terzah M. Horton
Journal: Blood
Blood (2023) 142 (Supplement 1): 2872.
https://doi.org/10.1182/blood-2023-180414
Published: 2023
Journal Articles

Preliminary Safety and Efficacy of Venetoclax and Selinexor in Combination with Chemotherapy in Pediatric and Young Adult Patients with Relapsed or Refractory Acute Myeloid Leukemia: Selclax

Sara Zarnegar-Lumley, Seth E. Karol, Stanley Pounds, Jeffery M. Klco, Maria Luisa Sulis, Dennis John Kuo, Kenneth Matthew Heym, Kathleen Ludwig, Alexandra McLean Stevens, Thomas B. Alexander, Kelly Elizabeth Faulk, Himalee S. Sabnis, Sarah K. Tasian, Jeffrey Taub, Andrew E. Place, Jeffrey E. Rubnitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 56.
https://doi.org/10.1182/blood-2023-174342
Published: 2023
Journal Articles

A DNA Methylation Signature Predicts Clinical Outcome in Pediatric AML Patients

Francisco Marchi, Marieke Landwehr, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Alan S Gamis, E. Anders Kolb, Richard Aplenc, Stanley Pounds, Todd A. Alonzo, Soheil Meshinchi, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 835.
https://doi.org/10.1182/blood-2023-186505
Published: 2023
Journal Articles

GWAS Identifies Variants Associated with Minimal Residual Disease after Induction I in Pediatric Patients with Newly Diagnosed Acute Myeloid Leukemia

Richard J Marrero, Xueyuan Cao, Huiyun Wu, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2023) 142 (Supplement 1): 2967.
https://doi.org/10.1182/blood-2023-179946
Published: 2023
Journal Articles

Zegocractin to Reduce the Severity of Asparaginase Associated Pancreatitis in Children with Acute Lymphoblastic Leukemia: Results of the Phase 1 Portion of the Crspa Study

Seth E. Karol, Haitao Pan, Zhou Yinmei, Jeffrey E. Rubnitz, Nickhill Bhakta, Sima Jeha, Mary V. Relling, Kristine R Crews, John C Panetta, Cara Morin, Cheng Cheng, Ching-Hon Pui, Hiroto Inaba, M Beth McCarville
Journal: Blood
Blood (2023) 142 (Supplement 1): 2837.
https://doi.org/10.1182/blood-2023-188357
Published: 2023
Journal Articles

Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions

Georgina L. Ryland, Masayuki Umeda, Linda Holmfeldt, Sören Lehmann, Morten Krogh Herlin, Jing Ma, Mahsa Khanlari, Jeffrey E. Rubnitz, Rhonda E. Ries, Hansen J. Kosasih, Paul G. Ekert, Hwee Ngee Goh, Ing S. Tiong, Sean M. Grimmond, Claudia Haferlach, Ryan B. Day, Timothy J. Ley, Soheil Meshinchi, Xiaotu Ma, Piers Blombery, Jeffery M. Klco
Journal: Blood
Blood (2023) 141 (7): 800–805.
https://doi.org/10.1182/blood.2022017874
Published: 2023
Includes: Supplemental data
Journal Articles

A Cibersortx Signature Predicts Outcome in Pediatric AML Patients

Francisco Marchi, Fernando Sckaff, Xueyuan Cao, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds, Jatinder K. Lamba
Journal: Blood
Blood (2022) 140 (Supplement 1): 3441–3442.
https://doi.org/10.1182/blood-2022-163366
Published: 2022
Journal Articles

Personalization of Induction Therapy for Pediatric AML to Ara-C+Dauno+ Etoposide (ADE) or Clofarabine+Ara-C According to a Polygenic Ara-C SNP Score- ACS10

Jatinder K. Lamba, Richard J Marrero, Abdelrahman H Elsayed, Xueyuan Cao, Huiyun Wu, Hiroto Inaba, Susana C. Raimondi, Ching-Hon Pui, Raul C. Ribeiro, Jeffrey E. Rubnitz, Stanley B. Pounds
Journal: Blood
Blood (2022) 140 (Supplement 1): 1039–1040.
https://doi.org/10.1182/blood-2022-159657
Published: 2022
Journal Articles

Safety and Anti-Leukemic Activity of CD123-CAR T Cells in Pediatric Patients with AML: Preliminary Results from a Phase 1 Trial

Swati Naik, Renee M. Madden, Amanda Lipsitt, Timothy Lockey, Jennyfer Bran, Jeffrey E. Rubnitz, Jeffery Klco, Barry Shulkin, Sagar L. Patil, Sarah Schell, Jeoungeun John Park, Janice Riberdy, Na Shang, Jaquelyn T. Zoine, Jennifer Wallace, Elaine Harstead, Catherine Willis, Jean-Yves Metais, Deanna M. Langfitt, Sheng Zhou, Salem M. Akel, Michael M. Meagher, Brandon M. Triplett, Stephen Gottschalk, Mireya Paulina Velasquez
Journal: Blood
Blood (2022) 140 (Supplement 1): 4584–4585.
https://doi.org/10.1182/blood-2022-170201
Published: 2022