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Irene Manrique
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Journal Articles

Composition of the Immune Environment at Baseline Correlates with Time to Response and Treatment Outcome in Newly Diagnosed Transplant-Ineligible Multiple Myeloma (MM) Patients Randomized to Krd or Ktd Followed By Carfilzomib Maintenance or Observation (AGMT_MM 02 Study)

Irene Manrique, Richard Greil, Johannes Andel, Siegfried Sormann, Bernd L. Hartmann, Klaus Podar, Alexander Egle, Andreas Petzer, Niklas Zojer, Eberhard Gunsilius, Reinhard Ruckser, Boris Bozic, Clemens A. Schmitt, Sigrid Machherndl-Spandl, Hermine Agis, Martin Schreder, Song-Yau Wang, Wolfgang Willenbacher, Maria-Theresa Krauth, Christoph Tinchon, Michael Fillitz, Thomas Melchardt, Stefan Knop, Bruno Paiva, Heinz Ludwig
Journal: Blood
Blood (2021) 138 (Supplement 1): 1669.
DOI: https://doi.org/10.1182/blood-2021-150311
Published: 2021
Journal Articles

Prognostic Importance of Measurable Residual Disease (MRD) Kinetics and Progression-Free Survival (PFS) Benefit in MRD+ Patients (Pts) with Ixazomib Vs Placebo As Post-Induction Maintenance Therapy: Results from the Multicenter, Double-Blind, Phase 3 TOURMALINE-MM4 Trial in Non-Transplant Newly Diagnosed Multiple Myeloma (NDMM) Pts

Bruno Paiva, PhD, Irene Manrique, PhD, Nicola Giuliani, Michele Cavo, Christine Rojas, MD, Weijun Fu, MD PhD, María-Victoria Mateos, MD PhD, Meletios A Dimopoulos, Alexander Vorog, MD, Cong Li, PhD, Bingxia Wang, PhD, Richard J Labotka, MD, Ajeeta B Dash, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 20–21.
DOI: https://doi.org/10.1182/blood-2020-136105
Published: 2020
Journal Articles

Immunophenotyping of Baseline Bone Marrow Reveals a Specific Pattern of Immune Cells Associated with Greater Depth and Sustained Response in Newly Diagnosed Patients Randomized to Krd or Ktd Followed By Carfilzomib Maintenance or Control (AGMT MM 02 Study)

Irene Manrique, PhD, Richard Greil, MD, Johannes Andel, MD, Siegfried Sormann, MD, Bernd L. Hartmann, MD, Klaus Podar, MDPhD, Alexander Egle, MD, Andreas Petzer, MD, Niklas Zojer, MD, Reinhard Ruckser, MD, Boris Bozic, MD, Clemens A. Schmitt, MD, Sigrid Machherndl-Spandl, MD, Hermine Agis, MD, Martin Schreder, MD, Maria-Theresa Krauth, MD, Christoph Tinchon, MD, Michael Fillitz, MD, Thomas Melchardt, MD PhD, Bruno Paiva, PhD, Heinz Ludwig, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
DOI: https://doi.org/10.1182/blood-2020-140918
Published: 2020
Journal Articles

Immunogenomic identification and characterization of granulocytic myeloid-derived suppressor cells in multiple myeloma

Cristina Perez, Cirino Botta, Aintzane Zabaleta, Noemi Puig, Maria-Teresa Cedena, Ibai Goicoechea, Daniel Alameda, Edurne San José-Eneriz, Juana Merino, Paula Rodríguez-Otero, Catarina Maia, Diego Alignani, Patricia Maiso, Irene Manrique, David Lara-Astiaso, Amaia Vilas-Zornoza, Sarai Sarvide, Caterina Riillo, Marco Rossi, Laura Rosiñol, Albert Oriol, María-Jesús Blanchard, Rafael Rios, Anna Sureda, Jesus Martin, Rafael Martinez, Joan Bargay, Javier de la Rubia, Miguel-Teodoro Hernandez, Joaquin Martinez-Lopez, Alberto Orfao, Xabier Agirre, Felipe Prosper, Maria-Victoria Mateos, Juan-José Lahuerta, Joan Blade, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2020) 136 (2): 199–209.
DOI: https://doi.org/10.1182/blood.2019004537
Published: 2020
Includes: Supplemental data
Journal Articles

Flowct: A Semi-Automated Workflow for Deconvolution of Immunophenotypic Data and Objective Reporting on Large Datasets

Cirino Botta, MD, Catarina Maia, Cristina Pérez Ruiz, Irene Manrique, Juan José Garcés, Sara Rodríguez, PhD, Leire Burgos, Juana Merino, Aitziber Lopez Lopez, Noemi Puig, MD PhD, María Teresa Cedena, Artur Paiva, Marco Rossi, Pierosandro Tagliaferri, MD, Piefrancesco Tassone, MD, Massimo Gentile, MD, Ivan M. Borrello, MD, Laura Rosinol Dachs, Maria-Victoria Mateos, MD PhD, Juan-José Lahuerta, MD PhD, Joan Bladé, MD, Jesús San-Miguel, Bruno Paiva, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4355.
DOI: https://doi.org/10.1182/blood-2019-122088
Published: 2019