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Journal Articles

Effect of Mutation Allele Frequency on the Risk Stratification of Myelodysplastic Syndrome Patients

Wan Hsuan Lee, Chien-Chin Lin, Cheng-Hong Tsai, Mei-Hsuan Tseng, Yuan-Yeh Kuo, Ming-Chih Liu, Jih-Luh Tang, Hsun-I Sun, Yi-Kuang Chuang, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien
Journal: Blood
Blood (2022) 140 (Supplement 1): 6932–6933.
DOI: https://doi.org/10.1182/blood-2022-159872
Published: 2022
Journal Articles

Efficacy and Safety of Ropeginterferon Alfa-2b for Pre-Fibrotic Primary Myelofibrosis and DIPSS Low/Intermediate-1 Risk Myelofibrosis

Harinder Gill, Lester Au, Rita Yim, Lynn Chin, Vivian Li, Paul Lee, Garret MK Leung, Carmen Lee, Tony Kwun Yat Wu, Cheong Ngai, Ryan Ho, Albert Chun Fung Sin, Hsin-An Hou, Chih-Cheng Chen, Yok-Lam Kwong
Journal: Blood
Blood (2022) 140 (Supplement 1): 1522.
DOI: https://doi.org/10.1182/blood-2022-169613
Published: 2022
Journal Articles

Strategies for Alleviating Tyrosine Kinase Resistance in Acute Myeloid Leukemia By Modulating p53 Signaling Pathway with Small Molecules

Chi-Yang Tseng, Fang-Yu Lo, Yu-Hsuan Fu, Da-Liang Ou, Hsin-An Hou, Liang-In Lin
Journal: Blood
Blood (2022) 140 (Supplement 1): 3086–3087.
DOI: https://doi.org/10.1182/blood-2022-163072
Published: 2022
Journal Articles

Conditional Knock-out of Phf6 Decreases CD44 Expression on Naïve CD4 + T Cells and Skews the Differentiation Toward Regulatory T Cells in Mice

Tsung-Chih Chen, Chia-Lang Hsu, Chi-Yuan Yao, Yu-Ren Chen, Yueh-Chwen Hsu, Chein-Jun Kao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood
Blood (2022) 140 (Supplement 1): 2635–2636.
DOI: https://doi.org/10.1182/blood-2022-155984
Published: 2022
Journal Articles

A Three Gene Leukemic Stem Cell Signature Score Is Robustly Prognostic in Chronic Myelomonocytic Leukemia

Yu-Hung Wang, Chi-Yuan Yao, Chien-Chin Lin, Kristian Gurashi, Fabio Amaral, Andres Jerez, Tim C.P Somervaille, Hsin-An Hou, Wen-Chien Chou, Kiran Batta, Hwei-Fang Tien, Daniel H Wiseman
Journal: Blood
Blood (2022) 140 (Supplement 1): 1104–1105.
DOI: https://doi.org/10.1182/blood-2022-165449
Published: 2022
Journal Articles

Prognostic Relevance of Adult Acute Myeloid Leukemia Patients According to the 2022 European Leukemianet Risk Stratification

Min Yen Lo, Cheng-Hong Tsai, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Yen-Ling Peng, Cheng-An Hsu, Hsun-I Sun, Yi-Kuang Chuang, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien
Journal: Blood
Blood (2022) 140 (Supplement 1): 130–131.
DOI: https://doi.org/10.1182/blood-2022-168522
Published: 2022
Journal Articles

Primary Results of Stimulus-MDS1: A Randomized, Double-Blind, Placebo-Controlled Phase II Study of TIM-3 Inhibition with Sabatolimab Added to Hypomethylating Agents (HMAs) in Adult Patients with Higher-Risk Myelodysplastic Syndromes (MDS)

Amer M. Zeidan, Kiyoshi Ando, Odile Rauzy, Mehmet Turgut, Ming-Chung Wang, Roberto Cairoli, Hsin-An Hou, Yok-Lam Kwong, Montserrat Arnan Sangerman, Stef Meers, Vinod A. Pullarkat, Valeria Santini, Kamel Malek, Flavia Kiertsman, Jiaying Lyu, Pedro Marques Ramos, Pierre Fenaux, Yasushi Miyazaki, Uwe Platzbecker
Journal: Blood
Blood (2022) 140 (Supplement 1): 2063–2065.
DOI: https://doi.org/10.1182/blood-2022-158612
Published: 2022
Journal Articles

Healthcare Resource Utilization and Costs Associated with AL Amyloidosis: A Retrospective Matched Cohort Study

Hsin-An Hou, Shih-Pei Shen, Kuan-Chih Huang, Choo Hua Goh, Hong Qiu, Lee Anne Rothwell, Kwang-We Wu, Hitesh Chandwani, Yanfang Liu, Chao-Hsiun Tang
Journal: Blood
Blood (2022) 140 (Supplement 1): 10837–10838.
DOI: https://doi.org/10.1182/blood-2022-164464
Published: 2022
Journal Articles

Metabolic Profiling Reveals Cellular Reprogramming of Acute Myeloid Leukemia By Omipalisib through Serine Synthesis Pathway

Liang-In Lin, Tseng Chiyang, Yu-Hsuan Fu, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood
Blood (2021) 138 (Supplement 1): 3296.
DOI: https://doi.org/10.1182/blood-2021-149200
Published: 2021
Journal Articles

Machine Learning of Genomic Factors in 1,961 Patients with Acute Myeloid Leukemia Identifies Patients with Very Good or Very Poor Prognosis Who Do Not Benefit from Allogeneic Hematopoietic Cell Transplant in First Remission

Shaun Fleming, Cheng-Hong Tsai, Hartmut Döhner, Konstanze Döhner, Elli Papaemmanuil, Hwei-Fang Tien, John Reynolds, Andrew H. Wei, Hsin-An Hou
Journal: Blood
Blood (2021) 138 (Supplement 1): 225.
DOI: https://doi.org/10.1182/blood-2021-151972
Published: 2021
Journal Articles

Surpass-ET Trial: A Phase 3, Open-Label, Multicenter, Randomized, Active-Controlled Study to Assess Pharmacokinetics and Compare the Efficacy, Safety, and Tolerability of P1101 Vs Anagrelide As Second Line Therapy for Essential Thrombocythemia

Ruben A. Mesa, Norio Komatsu, Harinder Gill, Jie Jin, Sung-Eun Lee, Hsin-An Hou, Toshiaki Sato, Albert Qin, Raymond Urbanski, Weichung Shih, Oleh Zagrijtschuk, Craig Zimmerman, Srdan Verstovsek
Journal: Blood
Blood (2021) 138 (Supplement 1): 1491.
DOI: https://doi.org/10.1182/blood-2021-147417
Published: 2021
Journal Articles

RUNX1 Expression Can be Complementary to RUNX1 Mutation in MDS Prognostication

Yu-Hung Wang, Chi-Yuan Yao, Chien-Chin Lin, Chia-Lang Hsu, Hsin-An Hou, Hwei-Fang Tien, Wen-Chien Chou
Journal: Blood
Blood (2021) 138 (Supplement 1): 2614.
DOI: https://doi.org/10.1182/blood-2021-145422
Published: 2021
Journal Articles

Epidemiology of Light-Chain Amyloidosis: A Population-Based Cohort Study in Taiwan

Hsin-An Hou, Chao-Hsiun Tang, Choo Hua Goh, Sarah Siggins, Shih-Pei Shen, Hong Qiu, Wen-Chien Chou, Yanfang Liu
Journal: Blood
Blood (2021) 138 (Supplement 1): 1637.
DOI: https://doi.org/10.1182/blood-2021-147660
Published: 2021
Journal Articles

TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype

David A. Sallman, Amy F. McLemore, Amy L. Aldrich, Rami S. Komrokji, Kathy L. McGraw, Abhishek Dhawan, Susan Geyer, Hsin-An Hou, Erika A. Eksioglu, Amy Sullivan, Sarah Warren, Kyle J. MacBeth, Manja Meggendorfer, Torsten Haferlach, Steffen Boettcher, Benjamin L. Ebert, Najla H. Al Ali, Jeffrey E. Lancet, John L. Cleveland, Eric Padron, Alan F. List
Journal: Blood
Blood (2020) 136 (24): 2812–2823.
DOI: https://doi.org/10.1182/blood.2020006158
Published: 2020
Includes: Supplemental data
Journal Articles

Tfeb Links MYC Signaling to Epigenetic Control of Acute Myeloid Leukemia Cell Death and Differentiation

Seongseok Yun, MDPhD, Nicole D. Vincelette, PhD, Mario Fernandez, Xiaoqing Yu, PhD, Chunying Yang, Taro Hitosugi, PhD, Chia-Ho Cheng, PhD, Audrey Freischel, Ling Zhang, MD, Gregory Watson, PhD, Weimin Li, Hsin-An Hou, MD PhD, Franz Xaver Schaub, PhD, Alexis Vedder, BS, Ling Cen, PhD, Kathy McGraw, PhD, Daniel Murphy, PhD, Andrea Ballabio, Scott H. Kaufmann, MD PhD, Anders Berglund, John L. Cleveland, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
DOI: https://doi.org/10.1182/blood-2020-137209
Published: 2020
Journal Articles

Accurate Prediction of Gene Mutations with Flow Cytometry Immune-Phenotyping By Machine Learning Algorithm

Bor-Sheng Ko, MD PhD, Yu-Fen Wang, MS, Jeng-Lin Li, BS, Hsin-An Hou, Wen-Chien Chou, MD PhD, Hwei-Fang Tien, MD, PhD, Ting-Yu Chang, M.S., Chi-Chun Lee, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
DOI: https://doi.org/10.1182/blood-2020-139623
Published: 2020
Journal Articles

Prognostic Prediction with Static-Dynamic Clinical and Pathological Parameters By Machine Learning Algorithm in Acute Lymphoblastic Leukemia

Bor-Sheng Ko, MD PhD, Yu-Fen Wang, MS, Jeng-Lin Li, BS, Hsin-An Hou, Wen-Chien Chou, MD PhD, Hwei-Fang Tien, MD, PhD, Ting-Yu Chang, M.S., Chi-Chun Lee, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1.
DOI: https://doi.org/10.1182/blood-2020-139766
Published: 2020
Journal Articles

Polatuzumab Vedotin-Based Salvage Chemotherapy in the Third-Line or Above Treatment for Diffuse Large B-Cell Lymphoma

Cheng-Hong Tsai, MD MSc, Feng Ming Tien, MD MSc, Hsin-An Hou, MD PhD, Jia-Hau Liu, MD, Shang-Ju Wu, MD PhD, Yu-Wen Wang, MSc., Chien-Chin Lin, MD, Bor-Sheng Ko, MD PhD, Wen-Chien Chou, MD PhD, Yun-Chu Lin, MD, Chieh-Lung Cheng, MD, Li-Chun Lu, MD PhD, Sung-Hsin Kuo, MD PhD, Ruey-Long Hong, MD PhD, Tai-Chung Huang, MD PhD, Ming Yao, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 12.
DOI: https://doi.org/10.1182/blood-2020-138481
Published: 2020
Journal Articles

Use of Machine Learning in 2074 Cases of Acute Myeloid Leukemia for Genetic Risk Profiling

Shaun Fleming, MBBS,, Cheng-Hong Tsai, MD MSc, Hartmut Döhner, MD, Konstanze Döhner, Elli Papaemmanuil, PhD, Hwei-Fang Tien, MD, PhD, John Reynolds, PhD, Andrew H. Wei, PhD FRACP, FRCPA, MBBS, Hsin-An Hou
Journal: Blood
Blood (2019) 134 (Supplement_1): 1392.
DOI: https://doi.org/10.1182/blood-2019-128243
Published: 2019
Journal Articles

Interim Analysis of Registry of Ruxolitinib Treatment in Patients with Intermediate-2 or High Risk Primary Myelofibrosis (PMF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), or Post-Essential Thrombocythemia Myelofibrosis (PET-MF) in Taiwan

Hsin-An Hou, Chien-Chin Lin, MD, Ming-Chung Kuo, MD, Shyuann-Yuh Lin, MD, Jyh-Pyng Gau, MD, Ming-Chung Wang, MD, Ming-Chih Chang, MD, Tsung-Chih Chen, MD, Su-Peng Yeh, MD, Yeu-Chin Chen, MD, Cih-En Huang, MD, Chieh-Wen Chen, MD, Yee-Ming Lee, PhD, Fan-Chen Ku, MD, Lee-Yung Shih, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5374.
DOI: https://doi.org/10.1182/blood-2019-129645
Published: 2019