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Journal Articles

Pretransplant MRD detection of fusion transcripts is strongly prognostic in KMT2A- rearranged acute myeloid leukemia

Sun Loo, Nicola Potter, Adam Ivey, Jenny O’Nions, Roderick Moon, Jelena Jovanovic, Chun Y. Fong, Natasha S. Anstee, Ing Soo Tiong, Jad Othman, Chong Chyn Chua, Hanna Renshaw, Robert Baker, Shaun Fleming, Nigel H. Russell, David Ritchie, Ashish Bajel, Hsin-An Hou, Richard Dillon, Andrew H. Wei
Journal: Blood
Blood (2024) 144 (24): 2554–2557.
https://doi.org/10.1182/blood.2024026605
Published: 2024
Includes: Supplemental data
Journal Articles

Modified Delphi Process to Develop Best Practice Recommendations for Myelofibrosis Management in Routine Clinical Practice in the Asia-Pacific Region (The APAC-MF Alliance)

Harinder Gill, Chul Won Choi, Hein Than, Hsin-An Hou, Chul Won Jung, Yok-Lam Kwong, Garret M. K. Leung, Melissa G. M. Ooi, Ponlapat Rojnuckarin, David M. Ross, Lee-Yung Shih, Katsuto Takenaka, Winnie Z. Y. Teo, Keita Kirito
Journal: Blood
Blood (2024) 144 (Supplement 1): 3678.
https://doi.org/10.1182/blood-2024-201402
Published: 2024
Journal Articles

Incorporating TET2 Variant Allele Frequency Enhances Prognostication in CMML: Insights from 849 Patients across Multiple Institutions

Yu-Hung Wang, Dorothée Selimoglu-Buet, Carmelo Gurnari, Andres Jerez, Andrius Zucenka, Chi-Yuan Yao, Chien-Chin Lin, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Jaroslaw Maciejewski, Eric Solary, Kiran Batta, Daniel H Wiseman
Journal: Blood
Blood (2024) 144 (Supplement 1): 4579.
https://doi.org/10.1182/blood-2024-194319
Published: 2024
Journal Articles

Prognostic Role of NGS-Based MRD Assessment in FLT3 -TKD Mutated Patients with Acute Myeloid Leukemia

Isabell Arnhardt, Christian M. Vonk, Xavier Cheng-Hong Tsai, Felicitas R. Thol, Wen-Chien Chou, Hsin-An Hou, Razif Gabdoulline, Florian H. Heidel, Hwei-Fang Tien, Michael Heuser, Peter J. M. Valk
Journal: Blood
Blood (2024) 144 (Supplement 1): 2951.
https://doi.org/10.1182/blood-2024-207981
Published: 2024
Journal Articles

A Molecular-Based Ecosystem to Improve Personalized Medicine in Patients with Chronic Myelomonocytic Leukemia (CMML)

Luca Lanino, Anthony M. Hunter, Nico Gagelmann, Marie Robin, Claudia Sala, Daniele Dall'Olio, Carmelo Gurnari, Lorenzo Dall'Olio, Yu-Hung Wang, Lisa Pleyer, Blanca Xicoy, Guillermo Montalban-Bravo, Lee-Yung Shih, Tamanna Haque, Omar Abdel-Wahab, Klaus Geissler, Alex Bataller, Alexandre Bazinet, Manja Meggendorfer, Ilaria Carola Casetti, Elisabetta Sauta, Erica Travaglino, Laura Palomo, Lurdes Zamora, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Esperanza Such, Guillermo Sanz, Anne Sophie Kubasch, Cristina Castilla-Llorente, Claude-Éric Bulabois, Laetitia Souchet, Hussein Awada, Massimo Bernardi, Patrizia Chiusolo, Antonio Curti, Luisa Giaccone, Francesco Onida, Lorenza Maria Borin, Francesco Passamonti, Elisa Diral, Vladan Vucinic, Gregorio Maria Bergonzi, Maria Teresa Voso, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Giulia Maggioni, Cristina Astrid Tentori, Alessandro Buizza, Gianluca Asti, Matteo Zampini, Elena Riva, Mattia Delleani, Angela Consagra, Francesca Ficara, Armando Santoro, Luciana Carota, Tiziana Sanavia, Cesare Rollo, Ahmad Kiwan, Jennifer VanOudenhove, Piero Fariselli, Najla H. Al Ali, David Sallman, Wolfgang Kern, Guillermo Garcia-Manero, Swapna Thota, Elizabeth A. Griffiths, Matilde Yung Follo, Carlo Finelli, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Rafael Bejar, Felicitas R. Thol, Nicolaus Kröger, Pierre Fenaux, Raphael Itzykson, Timothy Aaron Graubert, Michaela Fontenay, Amer M. Zeidan, Rami S. Komrokji, Valeria Santini, Torsten Haferlach, Ulrich Germing, Saverio D'Amico, Gastone Castellani, Mrinal M. Patnaik, Eric Solary, Eric Padron, Matteo Giovanni Della Porta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1003.
https://doi.org/10.1182/blood-2024-200104
Published: 2024
Journal Articles

Disease-Modifying Activity of Navtemadlin Correlates with Clinical Responses in a Randomized, Multicenter, Global Phase 3 Study (BOREAS) in JAK-Inhibitor Relapsed/Refractory Myelofibrosis

John O. Mascarenhas, Prithviraj Bose, Hsin-An Hou, Wojciech Homenda, David Ross, Sanjay R Mohan, Jean-Jacques Kiladjian, Haifa Kathrin Al-Ali, Andrew Perkins, Yulia Khalina, Tracy Clevenger, Zhuying Huang, Jesse McGreivy, Wayne Rothbaum, Srdan Verstovsek, Alessandro M. Vannucchi
Journal: Blood
Blood (2024) 144 (Supplement 1): 483.
https://doi.org/10.1182/blood-2024-205937
Published: 2024
Journal Articles

Artificial-Intelligence, Data-Driven, Comprehensive Classification of Myeloid Neoplasms Based on Genomic, Morphological and Histological Features

Luca Lanino, Saverio D'Amico, Giulia Maggioni, Najla H. Al Ali, Yu-Hung Wang, Carmelo Gurnari, Nico Gagelmann, Jan Philipp Bewersdorf, Somedeb Ball, Paola Guglielmelli, Manja Meggendorfer, Anthony M. Hunter, Anne Sophie Kubasch, Erica Travaglino, Alessia Campagna, Marta Ubezio, Antonio Russo, Gabriele Todisco, Cristina Astrid Tentori, Alessandro Buizza, Elisabetta Sauta, Matteo Zampini, Elena Riva, Gianluca Asti, Mattia Delleani, Francesca Ficara, Armando Santoro, Claudia Sala, Daniele Dall'Olio, Lorenzo Dall'Olio, Tariq Kewan, Ilaria Carola Casetti, Hussein Awada, Blanca Xicoy, Vladan Vucinic, Hsin-An Hou, Wen-Chien Chou, Chi-Yuan Yao, Chien-Chin Lin, Hwei-Fang Tien, Angela Consagra, David Sallman, Wolfgang Kern, Massimo Bernardi, Patrizia Chiusolo, Lorenza Maria Borin, Maria Teresa Voso, Lisa Pleyer, Laura Palomo, David Quintela, Andres Jerez, Elena Cornejo, Paloma Garcia Martin, Marina Díaz-Beyá, Alejandro Avendaño Pita, Veronica Roldan, Dolly Viviana Fiallo Suarez, Estefania Cerezo Velasco, Marisa Calabuig, Guillermo Garcia-Manero, Sanam Loghavi, Uwe Platzbecker, Francesc Sole, Maria Diez-Campelo, Jaroslaw Maciejewski, Nicolaus Kröger, Pierre Fenaux, Michaela Fontenay, Valeria Santini, Torsten Haferlach, Ulrich Germing, Eric Padron, Marie Robin, Francesco Passamonti, Eric Solary, Alessandro M. Vannucchi, Gastone Castellani, Amer M. Zeidan, Rami S. Komrokji, Matteo Giovanni Della Porta
Journal: Blood
Blood (2024) 144 (Supplement 1): 1005.
https://doi.org/10.1182/blood-2024-204826
Published: 2024
Journal Articles

Clinical Characteristics and Prognostic Implication for Myelodysplastic Syndromes/Neoplasms Patients with or without Cytogenetic Abnormalities or Gene Mutations

Wan Hsuan Lee, Chien-Chin Lin, Cheng-Hong Tsai, Feng-Ming Tien, Min Yen Lo, Mei-Hsuan Tseng, Yuan-Yeh Kuo, Shan-Chi Yu, Ming-Chih Liu, Chang-Tsu Yuan, Hwei-Fang Tien, Hsin-An Hou, Wen-Chien Chou
Journal: Blood
Blood (2024) 144 (Supplement 1): 6752.
https://doi.org/10.1182/blood-2024-211540
Published: 2024
Journal Articles

Characteristics and Long-Term Efficacy of 25 Patients with Paroxysmal Nocturnal Hemoglobinuria Treated with Eculizumab or Ravulizumab in Taiwan

Hsing-Yu Lin, Yu-Wen Chen, Ta-Chuan Yu, Feng-Ming Tien, Chien-Chin Lin, Sheng-Chieh Chou, Shang-Ju Wu, Bor-Sheng Ko, Yung-Li Yang, Ming Yao, Woei Tsay, Hwei-Fang Tien, Hsin-An Hou, Wen-Chien Chou
Journal: Blood
Blood (2024) 144 (Supplement 1): 5672.
https://doi.org/10.1182/blood-2024-199918
Published: 2024
Journal Articles

Clinical Characteristics and Prognostic Significance of PWWP2B Expression in AML Patients Treated with Intensive Chemotherapy

Cheng-Yeh Chen, Xavier Cheng-Hong Tsai, Kuojui Sun, Feng-Ming Tien, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Yen-Ling Peng, Bor-Sheng Ko, Ming-Chih Liu, Chia-Wen Liu, Chien-Chin Lin, Ming Yao, Wen-Chien Chou, Hwei-Fang Tien, Hsin-An Hou
Journal: Blood
Blood (2024) 144 (Supplement 1): 6149.
https://doi.org/10.1182/blood-2024-209914
Published: 2024
Journal Articles

DOCK1 Expression Enhances the Activity of the Notch Signaling Pathway and Promotes the Proliferation and Survival of Acute Myeloid Leukemia Cells

Ming-En Lin, Yueh-Chwen Hsu, Hsueh-Ling Chiu, Chi-Yuan Yao, Chia-Hua Liu, Chein-Jun Kao, Chang-I Li, Chang-Tsu Yuan, Yi-Tsung Yang, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien
Journal: Blood
Blood (2024) 144 (Supplement 1): 6148.
https://doi.org/10.1182/blood-2024-209830
Published: 2024
Journal Articles

Clinical Features and Prognostic Implications of BCMA , BAFF , and APRIL Expression in Acute Myeloid Leukemia

Yun-Tzu Lin, Xavier Cheng-Hong Tsai, Kuojui Sun, Min Yen Lo, Feng-Ming Tien, Yuan-Yeh Kuo, Mei-Hsuan Tseng, Yen-Ling Peng, Yi-Kuang Chuang, Bor-Sheng Ko, Jih-Luh Tang, Hsun-I Sun, Ming-Chih Liu, Chia-Wen Liu, Chien-Chin Lin, Ming Yao, Wen-Chien Chou, Hsin-An Hou, Hwei-Fang Tien
Journal: Blood
Blood (2024) 144 (Supplement 1): 6159.
https://doi.org/10.1182/blood-2024-211928
Published: 2024
Journal Articles

TP53 status and impact on AML prognosis within the ELN 2022 risk classification

Clinical Trials & Observations
Shaun Fleming, Xavier Cheng-Hong Tsai, Rhiannon Morris, Hsin-An Hou, Andrew H. Wei
Journal: Blood
Blood (2023) 142 (23): 2029–2033.
https://doi.org/10.1182/blood.2023020855
Published: 2023
Includes: Supplemental data
Journal Articles

Ropeginterferon Alfa-2b for Pre-Fibrotic Primary Myelofibrosis and DIPSS Low/Intermediate-1 Risk Myelofibrosis: Durable Responses and Evidence of Disease Modification

Harinder Gill, Lester Au, Garret Man Kit Leung, Dorothy Tsai, Rita Yim, Lynn Chin, Vivian Li, Paul Lee, Albert Chun Fung Sin, Hsin An Hou, Chih-Cheng Chen, Yok Lam Kwong
Journal: Blood
Blood (2023) 142 (Supplement 1): 4562.
https://doi.org/10.1182/blood-2023-180922
Published: 2023
Journal Articles

Meter: A Multi-Country, Real-World Chart Review Study to Explore Treatment Patterns, Effectiveness and Healthcare Resource Utilization for Patients with Myelofibrosis

Vikas Gupta, Ciprian Tomuleasa, Gilberto Israel Barranco Lampon, Hsin-An Hou, Grzegorz Helbig, Argiris S. Symeonidis, Ibrahim Haznedaroglu, Kenny Galvez, Fernando Tatsch, Avijeet S Chopra, Meng Zhang, Tamas Vizkelety, David M Ross
Journal: Blood
Blood (2023) 142 (Supplement 1): 3205.
https://doi.org/10.1182/blood-2023-173942
Published: 2023
Journal Articles

Prognostic and Therapeutic Implications of TP53 expression in Chronic Myelomonocytic Leukaemia: Results of a Multicentre Study

Yu-Hung Wang, Chien-Chin Lin, Kristian Gurashi, Fabio Amaral, Chi-Yuan Yao, Joanna Storer, Luciano Nicosia, Bettina Wingelhofer, Hsin-An Hou, Andres Jerez, Wen-Chien Chou, Kiran Batta, Hwei-Fang Tien, Daniel H Wiseman
Journal: Blood
Blood (2023) 142 (Supplement 1): 3213.
https://doi.org/10.1182/blood-2023-180034
Published: 2023
Journal Articles

Modulating Metabolic Reprogramming By Phosphoglycerate Dehydrogenase (PHGDH) Inhibitors in Omipalisib-Refractory AML

Chi-Yang Tseng, Yu-Hsuan Fu, Ching-Ying Kuo, Hsin-An Hou, Da-Liang Ou, Liang-In Lin
Journal: Blood
Blood (2023) 142 (Supplement 1): 1432.
https://doi.org/10.1182/blood-2023-185713
Published: 2023
Journal Articles

Pre-Transplant Measurable Residual Disease (MRD) Detection of KMT2A- rearranged Acute Myeloid Leukemia Is Strongly Associated with Inferior Post-Transplant Outcome

Sun Loo, Nicola Potter, Adam Ivey, Jenny O'Nions, Roderick Moon, Chun Yew Fong, Natasha Anstee, Ing Soo Tiong, Chong Chyn Chua, Jad Othman, Hannah Renshaw, Robert Baker, Nigel H. Russell, Ashish Bajel, Hsin-An Hou, Richard Dillon, Andrew H. Wei
Journal: Blood
Blood (2023) 142 (Supplement 1): 1577.
https://doi.org/10.1182/blood-2023-185541
Published: 2023
Journal Articles

HMR Mutations Drive Poor Prognosis in Myelofibrosis Patients with Lower JAK2 V617F Allele Burden but Not in Those with Higher Allele Burden: Results of a Multicenter Study

Yu-Hung Wang, Carmelo Gurnari, Chao-Hung Wei, Hussein Awada, Chien-Chin Lin, Andrius Zucenka, Chi-Yuan Yao, Kristian Gurashi, Hsin-An Hou, Kiran Batta, Wen-Chien Chou, Jaroslaw P. Maciejewski, Daniel H Wiseman, Hwei-Fang Tien
Journal: Blood
Blood (2023) 142 (Supplement 1): 627.
https://doi.org/10.1182/blood-2023-179907
Published: 2023
Journal Articles

Dose Escalation of HLA-A2-WT1 CD3 T-Cell Bispecific Antibody in a Phase I Study in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML)

Martin Hutchings, Pau Montesinos, Armando Santoro, Hsin-An Hou, Maria Pilar Martinez-Sanchez, Susana Vives, Sara Galimberti, Tsai-Yun Chen, Marco Frigeni, Sylvain Garciaz, Olga Salamero, Su-Peng Yeh, Karen Yee, Gabriel Schnetzler, Teresa Barata, Silke Simon, Heather Hinton, Koorosh Korfi, Muriel Richard, Nino Keshelava, Marion Subklewe
Journal: Blood
Blood (2023) 142 (Supplement 1): 1537.
https://doi.org/10.1182/blood-2023-173302
Published: 2023