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Journal Articles

Ex Vivo Expansion of Human Mobilized Peripheral Blood Stem Cells Using Epigenetic Modifiers

Santosh Saraf, MD, Hiroto Araki, MD, PhD, Benjamin Petro, BS, Kazumi G Yoshinaga, MS, Simona Taioli, MS, Amer Sidani, MD, John G. Quigley, MD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2011) 118 (21): 1920.

https://doi.org/10.1182/blood.V118.21.1920.1920

Published: 2011

Journal Articles

Valproic Acid Results In Maintenance but Not Expansion of Transplantable Hematopoietic Stem Cells From Human Umbilical Cord Blood

Hiroto Araki, MD, PhD, Sudhakar Baluchamy, PhD, Benjamin Petro, Mirza Saqib Baig, PhD, Montha Suhangul, MD, John G. Quigley, MD, Naoyuki Katayama, MD, PhD, Nadim Mahmud, MD, PhD

Blood (2010) 116 (21): 827.

https://doi.org/10.1182/blood.V116.21.827.827

Published: 2010

Journal Articles

Bone Marrow CD34+ Cells Expanded On Human Brain Endothelial Cells Reconstitutes Lethally Irradiated Baboons in a Variable Manner.

Hiroto Araki, MD, PhD, John Chute, MD, Benjamin Petro, BS, Naoyuki Katayama, MD, PhD, Ronald Hoffman, MD, Nadim Mahmud, MD, PhD

Blood (2009) 114 (22): 3214.

https://doi.org/10.1182/blood.V114.22.3214.3214

Published: 2009

Journal Articles

In Vivo Treatment with Chromatin Modifying Agents Dramatically Increases Hematopoietic Stem Cell Numbers.

Benjamin Petro, BS, Hiroto Araki, MD, PhD, John G. Quigley, MD, Damiano Rondelli, MD, Nadim Mahmud, MD, PhD

Blood (2009) 114 (22): 370.

https://doi.org/10.1182/blood.V114.22.370.370

Published: 2009

Journal Articles

Ly6C + Inflammatory Monocytes Are Extrahepatic Precursors of Hepatic Stellate Cells in Liver Injury.

Masahiro Masuya, MD, PhD, Hiroto Araki, MD, PhD, Kohshi Ohishi, MD, PhD, Naoyuki Katayama, MD, PhD

Blood (2009) 114 (22): 2518.

https://doi.org/10.1182/blood.V114.22.2518.2518

Published: 2009

Journal Articles

Possible Epigenetic Regulation of Functionally Opposing Groups of Genes Involved in Ex Vivo Expansion of Cord Blood Stem Cells

Sudhakar Baluchamy, PhD, Benjamin Petro, BS, Hiroto Araki, MD, PhD, Valerie Lindgren, PhD, Nadim Mahmud, MD, PhD

Blood (2008) 112 (11): 3473.

https://doi.org/10.1182/blood.V112.11.3473.3473

Published: 2008

Journal Articles

Expansion of Cord Blood Stem Cells Mediated by Epigenetic Mechanisms Remain Permissive to External Environmental Cues

Hiroto Araki, MD, PhD, Kazumi Yoshinaga, MS, Sudhakar Baluchamy, PhD, Benjamin Petro, BS, Donald Lavelle, PhD, Joseph DeSimone, PhD, Naoyuki Katayama, MD, PhD, Nadim Mahmud, MD, PhD

Blood (2008) 112 (11): 3868.

https://doi.org/10.1182/blood.V112.11.3868.3868

Published: 2008

Journal Articles

Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential

Hiroto Araki, Kazumi Yoshinaga, Piernicola Boccuni, Yan Zhao, Ronald Hoffman, Nadim Mahmud

Blood (2006) 109 (8): 3570–3578.

https://doi.org/10.1182/blood-2006-07-035287

Published: 2006

Journal Articles

Environmental Cues Can Promote Symmetrical Division of Functional Human Hematopoietic Stem Cells.

Nadim Mahmud, MD, PhD, Kazumi Yoshinaga, MS, Craig Beam, PhD, Hiroto Araki, MD, PhD

Blood (2006) 108 (11): 1397.

https://doi.org/10.1182/blood.V108.11.1397.1397

Published: 2006

Journal Articles

Ex-Vivo Expansion of Marrow Repopulating Cells by Chromatin Modifying Agents Is Associated with Modulation of Expression of Genes Implicated in HSC Self-Renewal.

Hiroto Araki, MD, PhD, Kazumi Yoshinaga, MS, Ronald Hoffman, MD, Piernicola Boccuni, MD, Nadim Mahmud, MD, PhD

Blood (2006) 108 (11): 1670.

https://doi.org/10.1182/blood.V108.11.1670.1670

Published: 2006

Journal Articles

Allogeneic T cells induce rapid CD34 + cell differentiation into CD11c + CD86 + cells with direct and indirect antigen-presenting function

Javaneh Abbasian, Dolores Mahmud, Nadim Mahmud, Sandeep Chunduri, Hiroto Araki, Pavan Reddy, Ronald Hoffman, Mario Arpinati, James L. M. Ferrara, Damiano Rondelli

Blood (2006) 108 (1): 203–208.

https://doi.org/10.1182/blood-2005-11-4330

Published: 2006

Journal Articles

Different Histone Deacetylase Inhibitors Affect Distinct Cellular Targets within the Hierarchy of Hematopoietic Stem / Progenitor Cells.

Hiroto Araki, MD, PhD, Ronald Hoffman, MD, Nadim Mahmud, MD, PhD

Blood (2005) 106 (11): 1721.

https://doi.org/10.1182/blood.V106.11.1721.1721

Published: 2005

Journal Articles

Use of Chromatin Modifying Agents for Ex Vivo Expansion of Human Umbilical Cord Blood Stem Cells.

Hiroto Araki, MD, PhD, Nadim Mahmud, MD, PhD, Mohammed Milhem, MD, Mingjiang Xu, MD, PhD, Ronald Hoffman, MD

Blood (2005) 106 (11): 4208.

https://doi.org/10.1182/blood.V106.11.4208.4208

Published: 2005

Journal Articles

CD34 + CD90 + Cord Blood Cells Which Have Undergone Multiple Cell Divisions Retain Marrow Repopulating Potential.

Hiroto Araki, MD, PhD, Nadim Mahmud, MD, PhD, Mohammed Milhem, MD, Hetal S. Patel, MSc, Rafael Nunez, MD, Edward Bruno, MS, Ronald Hoffman, MD

Blood (2004) 104 (11): 3228.

https://doi.org/10.1182/blood.V104.11.3228.3228

Published: 2004

Journal Articles

In-Vitro and In-Vivo Effects of Autologous and Allogeneic Lymphocytes on Human Cord Blood CD34+ Cell Function.

Javaneh Abbasian, MS, Nadim Mahmud, MD, PhD, Hiroto Araki, MD, Edward Bruno, BS, Mario Arpinati, MD, PhD, Ronald Hoffman, MD, Damiano Rondelli, MD

Blood (2004) 104 (11): 4962.

https://doi.org/10.1182/blood.V104.11.4962.4962

Published: 2004

Journal Articles

Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A

Mohammed Milhem, Nadim Mahmud, Donald Lavelle, Hiroto Araki, Joseph DeSimone, Yogen Saunthararajah, Ronald Hoffman

Blood (2004) 103 (11): 4102–4110.

https://doi.org/10.1182/blood-2003-07-2431

Published: 2004

Journal Articles

Reprogramming of human postmitotic neutrophils into macrophages by growth factors

Hiroto Araki, Naoyuki Katayama, Yoshihiro Yamashita, Hiroyuki Mano, Atsushi Fujieda, Eiji Usui, Hidetsugu Mitani, Kohshi Ohishi, Kazuhiro Nishii, Masahiro Masuya, Nobuyuki Minami, Tsutomu Nobori, Hiroshi Shiku

Blood (2004) 103 (8): 2973–2980.

https://doi.org/10.1182/blood-2003-08-2742

Published: 2004

NARROW

Ex Vivo Expansion of Human Mobilized Peripheral Blood Stem Cells Using Epigenetic Modifiers

Valproic Acid Results In Maintenance but Not Expansion of Transplantable Hematopoietic Stem Cells From Human Umbilical Cord Blood

Bone Marrow CD34+ Cells Expanded On Human Brain Endothelial Cells Reconstitutes Lethally Irradiated Baboons in a Variable Manner.

In Vivo Treatment with Chromatin Modifying Agents Dramatically Increases Hematopoietic Stem Cell Numbers.

Ly6C + Inflammatory Monocytes Are Extrahepatic Precursors of Hepatic Stellate Cells in Liver Injury.

Possible Epigenetic Regulation of Functionally Opposing Groups of Genes Involved in Ex Vivo Expansion of Cord Blood Stem Cells

Expansion of Cord Blood Stem Cells Mediated by Epigenetic Mechanisms Remain Permissive to External Environmental Cues

Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential

Environmental Cues Can Promote Symmetrical Division of Functional Human Hematopoietic Stem Cells.

Ex-Vivo Expansion of Marrow Repopulating Cells by Chromatin Modifying Agents Is Associated with Modulation of Expression of Genes Implicated in HSC Self-Renewal.

Allogeneic T cells induce rapid CD34 + cell differentiation into CD11c + CD86 + cells with direct and indirect antigen-presenting function

Different Histone Deacetylase Inhibitors Affect Distinct Cellular Targets within the Hierarchy of Hematopoietic Stem / Progenitor Cells.

Use of Chromatin Modifying Agents for Ex Vivo Expansion of Human Umbilical Cord Blood Stem Cells.

CD34 + CD90 + Cord Blood Cells Which Have Undergone Multiple Cell Divisions Retain Marrow Repopulating Potential.

In-Vitro and In-Vivo Effects of Autologous and Allogeneic Lymphocytes on Human Cord Blood CD34+ Cell Function.

Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A

Reprogramming of human postmitotic neutrophils into macrophages by growth factors

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American Society of Hematology

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American Society of Hematology

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