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Hillard M. Lazarus
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Journal Articles

Lack of Benefit of Autologous Hematopoietic Cell Transplantation (auto-HCT) in Mantle Cell Lymphoma (MCL) Patients (pts) in First Complete Remission (CR) with Undetectable Minimal Residual Disease (uMRD): Initial Report from the ECOG-ACRIN EA4151 Phase 3 Randomized Trial

Free
Timothy S. Fenske, Xin Victoria Wang, Brian G. Till, Kristie A. Blum, Matthew Lunning, Hillard M. Lazarus, Paul A.S. Fishkin, Lale Kostakoglu Shields, David W. Scott, Ann S. LaCasce, Patrick B. Johnston, Amanda F. Cashen, Leslie L. Popplewell, Robert M. Dean, Nausheen Ahmed, Nirav N. Shah, Nina D. Wagner-Johnston, Boyu Hu, Bhagirathbhai R. Dholaria, Richard F. Little, Jonathan W. Friedberg, John P. Leonard, Brad S. Kahl
Journal: Blood
Blood (2024) 144 (Supplement 2): LBA-6.
https://doi.org/10.1182/blood-2024-212973
Published: 2024
Journal Articles

Assessment of Outcomes of Allogeneic Stem Cell Transplantation By Treatment Arm in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia Randomized to Conventional Chemotherapy +/- Blinatumomab in the ECOG-ACRIN E1910 Phase III National Clinical Trials Network Trial

Free
Michaela Liedtke, Zhuoxin Sun, Mark R. Litzow, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Bhave, Elad Sharon, Richard Little, Harry P. Erba, Richard M. Stone, Selina Luger, Charles G. Mullighan, Martin S. Tallman, Matthew J. Wieduwilt
Journal: Blood
Blood (2024) 144 (Supplement 1): 779.
https://doi.org/10.1182/blood-2024-207557
Published: 2024
Journal Articles

Uncovering the Tumor Antigen Landscape in Patients Undergoing Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance Treatment

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Dimitra Karagkouni, Giulia Cheloni, Shivani Nanda, Yuling Ma, Shuoshuo Wang, Leda Xanthi Katopodi, Isabella Saldarriaga, Yered Pita-Juarez, David J. Chung, Nina Shah, Natalie Callander, Binod Dhakal, Thinle Chodon, Nikhil C. Munshi, Kenneth C. Anderson, Yvonne A. Efebera, Peiman Hematti, Hillard M. Lazarus, Ehsan Malek, Philip L. McCarthy, Ajay K. Nooka, Krina K. Patel, Aaron P. Rapoport, Robert J. Soiffer, Edmund K. Waller, Marcelo C. Pasquini, Jacalyn Rosenblatt, David Avigan, Ioannis S Vlachos
Journal: Blood
Blood (2024) 144 (Supplement 1): 3289.
https://doi.org/10.1182/blood-2024-211352
Published: 2024
Journal Articles

Addition of Blinatumomab to Consolidation Therapy Among Older Newly Diagnosed Patients (pts) with BCR::ABL1 Negative B-Lineage Acute Lymphoblastic Leukemia (ALL) in the ECOG-ACRIN E1910 Randomized Phase III Trial

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Nikolai A. Podoltsev, Zhuoxin Sun, Mark R. Litzow, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevskis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W. Pratz, Shira N. Dinner, Noelle Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Cheryl L. Willman, Daniel J. DeAngelo, Shejal B. Patel, Michelle A Elliott, Anjali S. Advani, Dimitrios Tzachanis, Pankit Vachhani, Rupali Roy, Elad Sharon, Richard Little, Harry Erba, Richard M. Stone, Charles G. Mullighan, Martin S. Tallman, Selina Luger, Ryan J Mattison
Journal: Blood
Blood (2024) 144 (Supplement 1): 4211.
https://doi.org/10.1182/blood-2024-207143
Published: 2024
Journal Articles

131 I-Apamistamab Effectively Achieved Durable Responses in Patients with R/R AML Irrespective of the Presence of Multiple High-Risk Factors

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Stuart Seropian, James M. Foran, Boglarka Gyurkocza, Rajneesh Nath, Hannah Choe, Mark R. Litzow, Nebu Koshy, Patrick J. Stiff, Ben K. Tomlinson, Sunil Abhyankar, Sameem Abedin, George Chen, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Jennifer Spross, Kate L Li, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Camille N. Abboud
Journal: Blood
Blood (2023) 142 (Supplement 1): 2159.
https://doi.org/10.1182/blood-2023-187433
Published: 2023
Journal Articles

Older Adults with Acute Myeloid Leukemia (AML) Experience Improvement in Health-Related Quality of Life (HRQoL) Scores with Intensive Therapy: Prospective Study from ECOG-ACRIN (EA) E2906 Phase 3 Trial

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James M. Foran, Li Chen, Selina M Luger, Zhuoxin Sun, Heidi Klepin, David F. Claxton, Hillard M. Lazarus, Jacob M. Rowe, Jessica K. Altman, Aref Al-Kali, Hong Zheng, Keith W Pratz, Edward R. Broun, Bayard L Powell, Kristen M. O'Dwyer, Yishai Ofran, John E. Godwin, Mark R. Litzow, Martin S. Tallman, Lynne Wagner
Journal: Blood
Blood (2023) 142 (Supplement 1): 594.
https://doi.org/10.1182/blood-2023-189734
Published: 2023
Journal Articles

Assessment of Outcomes of Consolidation Therapy By Number of Cycles of Blinatumomab Received in Newly Diagnosed Measurable Residual Disease Negative Patients with B-Lineage Acute Lymphoblastic Leukemia: In the ECOG-ACRIN E1910 Randomized Phase III National Clinical Trials Network Trial

Free
Selina M Luger, Zhuoxin Sun, Ryan J Mattison, Elisabeth Paietta, Kathryn G. Roberts, Yanming Zhang, Janis Racevckis, Hillard M. Lazarus, Jacob M. Rowe, Daniel A. Arber, Matthew J. Wieduwilt, Michaela Liedtke, Julie Bergeron, Brent L. Wood, Yaqi Zhao, Gang Wu, Ti-Cheng Chang, Wenchao Zhang, Keith W Pratz, Shira N. Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L Uy, Deepa Jeyakumar, Tara L Lin, Cheryl L. Willman, Daniel J. DeAngelo, Elad Sharon, Richard F. Little, Harry P. Erba, Richard M Stone, Charles G. Mullighan, Mark R. Litzow, Martin S. Tallman
Journal: Blood
Blood (2023) 142 (Supplement 1): 2877.
https://doi.org/10.1182/blood-2023-189648
Published: 2023
Journal Articles

High-Dose Targeted Radiation with 131 I-Apamistamab Prior to HCT Demonstrated a Dose-Response for Durable Complete Remission in Patients with R/R AML

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Mark R. Litzow, George Chen, Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Camille N. Abboud, Nebu Koshy, Ben K. Tomlinson, Sunil Abhyankar, James M. Foran, Sameem Abedin, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Eugene Leung, Ming-Kai Chen, Mona Natwa, Jennifer Spross, Kate L Li, Norman Nagl, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Richard L. Wahl, Neeta Pandit-Taskar, Patrik Brodin, Patrick J. Stiff
Journal: Blood
Blood (2023) 142 (Supplement 1): 3529.
https://doi.org/10.1182/blood-2023-189040
Published: 2023
Journal Articles

131 I-Apamistamab-Led Allogeneic Hematopoietic Cell Transplant Significantly Improves Overall Survival in Patients with TP53 Mutated R/R AML

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Hannah Choe, Ben K. Tomlinson, Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Mark R. Litzow, Camille N. Abboud, Patrick J. Stiff, Sunil Abhyankar, James M. Foran, Sameem Abedin, George Chen, Zaid Al-Kadhimi, Partow Kebriaei, Mitchell Sabloff, Johnnie J. Orozco, Katarzyna Joanna Jamieson, Margarida Magalhaes-Silverman, Koen Van Besien, Michael W. Schuster, Arjun D. Law, Sebastian A. Mayer, Hillard M. Lazarus, Jennifer Spross, Kate L Li, Elaina Haeuber, Madhuri Vusirikala, Akash Nahar, Brenda M. Sandmaier, John Pagel, Sergio A. Giralt, Avinash Desai, Nebu Koshy
Journal: Blood
Blood (2023) 142 (Supplement 1): 469.
https://doi.org/10.1182/blood-2023-182177
Published: 2023
Journal Articles

Molecular Expression Differences in Blood Mononuclear Cells in Patients with AL Amyloidosis

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David Kaplan, Eric Christian, Jason Valent, Faiz Anwer, Shahzad Raza, Sandra Mazzoni, Christy J. Samaras, Louis S. Williams, Danai Dima, Kelly Shepherd, Jared Fennema, Sherry Fada, Megan Nakashima, Mazen Hanna, Hillard M. Lazarus, Jack Khouri
Journal: Blood
Blood (2023) 142 (Supplement 1): 5031.
https://doi.org/10.1182/blood-2023-180735
Published: 2023
Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Free
Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

PLX-R18 (Avoplacel), a Placental Expanded Mesenchymal-like Stromal Cell Therapy Shows Favorable Safety and Appears to Improve Incomplete Hematopoietic Recovery after Hematopoietic Cell Transplantation (HCT)

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Hillard M Lazarus, Joseph P. McGuirk, Tsila Zuckerman, Leland Metheny, Luis Pineiro, Mark R. Litzow, Scott D. Rowley, Batia Avni, Roni Tamari, Michal Sheleg, Daniel Rothenstein, Nitsan Halevy, Jacob M. Rowe
Journal: Blood
Blood (2022) 140 (Supplement 1): 10447–10448.
https://doi.org/10.1182/blood-2022-169266
Published: 2022
Journal Articles

Impact of Autologous Hematopoietic Cell Transplant (HCT) Followed By Dendritic Cell/Myeloma Fusion Vaccine with Lenalidomide Maintenance in Increasing Multiple Myeloma (MM) Immunity (BMT CTN 1401)

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David J. Chung, Nina Shah, Dina Stroopinsky, Juan WU, Lina Bisharat, Natalie S. Callander, Brent R. Logan, Kenneth C. Anderson, Thinle Chodon, Meera Mohan, Steven Devine, Yvonne A. Efebera, Nancy Geller, Peiman Hematti, Leona A. Holmberg, Alan Howard, Bryon Johnson, Hillard M Lazarus, Ehsan Malek, Philip L. McCarthy, David H. McKenna, Adam M. Mendizabal, Nikhil C. Munshi, Lynn O'Donnell, Aaron P. Rapoport, Ajay K. Nooka, Jane Reese, Robert J. Soiffer, Lynne Uhl, Giulia Cheloni, Dimitra Karagkouni, Ioannis Vlachos, James W. Young, Jacalyn Rosenblatt, Edmund K. Waller, Marcelo C Pasquini, David Avigan
Journal: Blood
Blood (2021) 138 (Supplement 1): 899.
https://doi.org/10.1182/blood-2021-149659
Published: 2021
Journal Articles

Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study

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Yishai Ofran, Zhuoxin Sun, Jacob M. Rowe, David F. Claxton, Martin S. Tallman, Daniel A. Arber, Ari Melnick, Ross L. Levine, Elisabeth Paietta, John E. Godwin, Hillard M Lazarus, Selina M. Luger, James M. Foran, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 413.
https://doi.org/10.1182/blood-2021-149356
Published: 2021
Journal Articles

Patients with AML Who Achieve Long Term Complete Remission Do Not Have a Normal Life Expectancy When Compared to the General Population. Analysis of 3,012 Patients Enrolled on 9 Consecutive ECOG-ACRIN Trials

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Chezi Ganzel, Kevin Roopcharan, Zhuoxin Sun, Jacob M. Rowe, Hugo F Fernandez, Elisabeth M. Paietta, Selina M. Luger, Hillard M Lazarus, Larry D Cripe, Dan Douer, Peter H. Wiernik, Martin S. Tallman, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 690.
https://doi.org/10.1182/blood-2021-149208
Published: 2021
Journal Articles

Clinical Experience in the Randomized Phase 3 Sierra Trial: Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] Conditioning Enables Hematopoietic Cell Transplantation with Successful Engraftment and Acceptable Safety in Patients with Active, Relapsed/Refractory AML Not Responding to Targeted Therapies

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Boglarka Gyurkocza, Rajneesh Nath, Stuart Seropian, Hannah Choe, Mark R. Litzow, Nebu V. Koshy, Patrick Stiff, Camille Abboud, Sr., Benjamin Tomlinson, Sunil Abhyankar, Parameswaran Hari, Zaid S. Al-Kadhimi, George L. Chen, Mitchell Sabloff, Johnnie J. Orozco, James M. Foran, Partow Kebriaei, Katarzyna Joanna Jamieson, Margarida Magalhaes Magalhaes-Silverman, Koen van Besien, Michael W. Schuster, Arjun Law, Moshe Levy, Hillard M Lazarus, Sergio A Giralt, Mark S. Berger, Jennifer A Spross, Avinash G Desai, Vijay Reddy, John M. Pagel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1791.
https://doi.org/10.1182/blood-2021-148497
Published: 2021
Journal Articles

Molecular classification improves risk assessment in adult BCR-ABL1– negative B-ALL

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Elisabeth Paietta, Kathryn G. Roberts, Victoria Wang, Zhaohui Gu, Georgina A. N. Buck, Deqing Pei, Cheng Cheng, Ross L. Levine, Omar Abdel-Wahab, Zhongshan Cheng, Gang Wu, Chunxu Qu, Lei Shi, Stanley Pounds, Cheryl L. Willman, Richard Harvey, Janis Racevskis, Jan Barinka, Yanming Zhang, Gordon W. Dewald, Rhett P. Ketterling, David Alejos, Hillard M. Lazarus, Selina M. Luger, Letizia Foroni, Bela Patel, Adele K. Fielding, Ari Melnick, David I. Marks, Anthony V. Moorman, Peter H. Wiernik, Jacob M. Rowe, Martin S. Tallman, Anthony H. Goldstone, Charles G. Mullighan, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (11): 948–958.
https://doi.org/10.1182/blood.2020010144
Published: 2021
Includes: Supplemental data
Journal Articles

Posttransplant cyclophosphamide is associated with increased cytomegalovirus infection: a CIBMTR analysis

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Clinical Trials & Observations
Scott R. Goldsmith, Muhammad Bilal Abid, Jeffery J. Auletta, Asad Bashey, Amer Beitinjaneh, Paul Castillo, Roy F. Chemaly, Min Chen, Stefan Ciurea, Christopher E. Dandoy, Miguel Ángel Díaz, Ephraim Fuchs, Siddhartha Ganguly, Christopher G. Kanakry, Jennifer A. Kanakry, Soyoung Kim, Krishna V. Komanduri, Maxwell M. Krem, Hillard M. Lazarus, Hongtao Liu, Per Ljungman, Richard Masiarz, Carolyn Mulroney, Sunita Nathan, Taiga Nishihori, Kristin M. Page, Miguel-Angel Perales, Randy Taplitz, Rizwan Romee, Marcie Riches
Journal: Blood
Blood (2021) 137 (23): 3291–3305.
https://doi.org/10.1182/blood.2020009362
Published: 2021
Includes: Supplemental data
Journal Articles

Neighborhood poverty and pediatric allogeneic hematopoietic cell transplantation outcomes: a CIBMTR analysis

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Clinical Trials & Observations
Kira Bona, Ruta Brazauskas, Naya He, Leslie Lehmann, Hisham Abdel-Azim, Ibrahim A Ahmed, A Samer Al-Homsi, Mahmoud Aljurf, Staci D. Arnold, Sherif M Badawy, Minoo Battiwalla, Sara Beattie, Neel S. Bhatt, Jignesh Dalal, Christopher E. Dandoy, Miguel Angel Diaz, Haydar A. Frangoul, César O. Freytes, Siddhartha Ganguly, Biju George, David Gomez-Almaguer, Theresa Hahn, Rammurti T. Kamble, Jennifer M. Knight, C. Fred LeMaistre, Jason Law, Hillard M. Lazarus, Navneet S. Majhail, Richard F. Olsson, Jaime Preussler, Bipin N. Savani, Raquel Schears, Sachiko Seo, Akshay Sharma, Alok Srivastava, Amir Steinberg, David Szwajcer, Baldeep Wirk, Ayami Yoshimi, Nandita Khera, William A. Wood, Shahrukh Hashmi, Christine N. Duncan, Wael Saber
Journal: Blood
Blood (2021) 137 (4): 556–568.
https://doi.org/10.1182/blood.2020006252
Published: 2021
Includes: Supplemental data
Journal Articles

Personalized Targeted Radioimmunotherapy with Anti-CD45 Iodine ( 131 I) Apamistamab [Iomab-B] in Patients with Active Relapsed or Refractory Acute Myeloid Leukemia Results in Successful Donor Hematopoietic Cells Engraftment with the Timing of Engraftment Not Related to the Radiation Dose Delivered

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Boglarka Gyurkocza, MD, Rajneesh Nath, MD, Hannah Choe, MD, Stuart Seropian, MD, Patrick J. Stiff, MD, Sunil Abhyankar, MD, Edward Agura, MD, Mark Litzow, MD, Benjamin K. Tomlinson, MD, George L. Chen, MD, Parameswaran Hari, MD MRCP, Johnnie Orozco, MD, Zaid S. Al-Kadhimi, MD, Camille Abboud, MD, Koen Van Besien, MD PhD, Mitchell Sabloff, MSc,MDFRCPC, Margarida Magalhaes Magalhaes-Silverman, James M. Foran, MD, Michael W. Schuster, MD, Partow Kebriaei, MD, Moshe Y. Levy, MD, Hillard M Lazarus, MD, Sergio A. Giralt, MD, Qing Liang, PhD, Mark S. Berger, MD, Vijay Reddy, MDPhD, John M. Pagel, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 42–44.
https://doi.org/10.1182/blood-2020-134948
Published: 2020