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Journal Articles

PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy

Blood (2017) 129 (15): 2186–2197.

https://doi.org/10.1182/blood-2016-09-741629

Published: 2017

Includes: Supplemental data

Journal Articles

Programming of donor T cells using allogeneic δ-like ligand 4–positive dendritic cells to reduce GVHD in mice

Kazuhiro Mochizuki, Lijun Meng, Izumi Mochizuki, Qing Tong, Shan He, Yongnian Liu, Janaki Purushe, Henry Fung, M. Raza Zaidi, Yanyun Zhang, Ran Reshef, Bruce R. Blazar, Hideo Yagita, Shin Mineishi, Yi Zhang

Blood (2016) 127 (25): 3270–3280.

https://doi.org/10.1182/blood-2015-05-644476

Published: 2016

Includes: Supplemental data

Journal Articles

PD-1 Signaling Has a Critical Role in Maintaining Regulatory T Cell Homeostasis; Implication for Treg Depletion Therapy By PD-1 Blockade

Takeru Asano, MD, Yuriko Kishi, Yusuke Meguri, MD, Takanori Yoshioka, MD, Miki Iwamoto, Yoshinobu Maeda, MD PhD, Hideo Yagita, PhD, Mitsune Tanimoto, MD PhD, John Koreth, MBBS, DPhil, Jerome Ritz, MD, Ken-Ichi Matsuoka, MDPhD

Blood (2015) 126 (23): 848.

https://doi.org/10.1182/blood.V126.23.848.848

Published: 2015

Journal Articles

The Notch Ligand DLL4 Derived from Human Dendritic Cells Is Critical for Promoting T Helper (Th)1 and Th17 Cell Differentiation

Lijun Meng, Zhenjiang Bai, Shan He, Kazuhiro Mochizuki, MD PhD, Janaki Purushe, Hongxing Sun, Jian Wang, Hideo Yagita, PhD, Shin Mineishi, MD, Henry Fung, Gregory A. Yanik, MD, Roberto Caricchio, Xiaoxuan Fan, Lisa M Crisalli, Ran Reshef, MD, Yanyun Zhang, Yi Zhang

Blood (2015) 126 (23): 3431.

https://doi.org/10.1182/blood.V126.23.3431.3431

Published: 2015

Journal Articles

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Kazuhiro Mochizuki, MD PhD, Lijun Meng, Izumi Mochizuki, MD, Qing Tong, MD, Shan He, Yongnian Liu, Janaki Purushe, Hongxing Sun, Henry Fung, Raza Zaidi, Ran Reshef, MD, Bruce R. Blazar, MD, Hideo Yagita, PhD, Shin Mineishi, MD, Yi Zhang

Blood (2015) 126 (23): 233.

https://doi.org/10.1182/blood.V126.23.233.233

Published: 2015

Journal Articles

Enhanced Expression of PD-1 Modulates CD4+Foxp3+ Regulatory T Cell Homeostasis during Low-Dose IL-2 Therapy in Patients with Chronic Graft-Versus-Host Disease

Takeru Asano, MD, Haesook T. Kim, PhD, John Koreth, MBBS, DPhil, Robert J Soiffer, MD, Yusuke Meguri, MD, Takanori Yoshioka, MD, Hideo Yagita, PhD, Mitsune Tanimoto, MD PhD, Jerome Ritz, MD, Ken-ichi Matsuoka, MD PhD

Blood (2014) 124 (21): 662.

https://doi.org/10.1182/blood.V124.21.662.662

Published: 2014

Journal Articles

Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells

Hideaki Fujiwara, Yoshinobu Maeda, M.D., Ph.D., Koichiro Kobayashi, Hisakazu Nishimori, Ken-ichi Matsuoka, MD, PhD, Miyuki Azuma, MD, PhD, Hideo Yagita, PhD, Lieping Chen, MD, PhD, Mitsune Tanimoto, MD, PhD

Blood (2013) 122 (21): 3244.

https://doi.org/10.1182/blood.V122.21.3244.3244

Published: 2013

Journal Articles

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Asim Saha, Kazutoshi Aoyama, Patricia A. Taylor, Brent H. Koehn, Rachelle G. Veenstra, Angela Panoskaltsis-Mortari, David H. Munn, William J. Murphy, Miyuki Azuma, Hideo Yagita, Brian T. Fife, Mohammed H. Sayegh, Nader Najafian, Gerard Socie, Rafi Ahmed, Gordon J. Freeman, Arlene H. Sharpe, Bruce R. Blazar

Blood (2013) 122 (17): 3062–3073.

https://doi.org/10.1182/blood-2013-05-500801

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Kazuhiro Mochizuki, MD, PhD, Fang Xie, MD, Shan He, PhD, Qing Tong, MS, Yongnian Liu, MS, Yajun Guo, MD, PhD, Koji Kato, MD, PhD, Hideo Yagita, PhD, Shin Mineishi, Yi Zhang, MD, PhD

Blood (2012) 120 (21): 337.

https://doi.org/10.1182/blood.V120.21.337.337

Published: 2012

Journal Articles

Polyfunctional CD4 + T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy

Zhi-Chun Ding, Lei Huang, Bruce R. Blazar, Hideo Yagita, Andrew L. Mellor, David H. Munn, Gang Zhou

Blood (2012) 120 (11): 2229–2239.

https://doi.org/10.1182/blood-2011-12-398321

Published: 2012

Includes: Supplemental data

Journal Articles

BCR-ABL Regulates Death Receptor Expression for TNF-Related Apoptosis-Inducing Ligand (TRAIL) in Philadelphia Chromosome-Positive Leukemia

Itaru Kuroda, MD, PhD, Takeshi Inukai, MD, PhD, Xiaochun Zhang, MD, PhD, Jiro Kikuchi, Yusuke Furukawa, Atsushi Nemoto, MD, PhD, Koshi Akahane, MD, PhD, Kinuko Hirose, MD, PhD, Hiroko Honna- Oshiro, MD, PhD, Kumiko Goi, MD, PhD, Keiko Kagami, Hideo Yagita, PhD, Tetsuzo Tauchi, M.D., Yasuhiro Maeda, MD, PhD, Kanji Sugita, MD, PhD

Blood (2011) 118 (21): 2740.

https://doi.org/10.1182/blood.V118.21.2740.2740

Published: 2011

Journal Articles

Dll4 Blockade Modifies the Bone Marrow Vascular Niche and Improves Donor Bone Marrow Cells for Bone Marrow Transplant

Leonor Remédio, Tânia Carvalho, Francisco Caiado, Ana Bastos Carvalho, António Duarte, Hideo Yagita, Sérgio Dias

Blood (2011) 118 (21): 1321.

https://doi.org/10.1182/blood.V118.21.1321.1321

Published: 2011

Journal Articles

Allogeneic Cytokine-Induced Killer Cells Kill Dendritic Cells Efficiently Resulting in Less Graft-Versus-Host Disease

Shintaro Mase, MD, Hideaki Maeba, MD, Rie Kuroda, MD, Raita Araki, MD, Toshihiro Fujiki, MD, Hideo Yagita, PhD, Akihiro Yachie, MD, PhD, Shoichi Koizumi, MD, PhD, Ryosei Nishimura, MD, PhD

Blood (2011) 118 (21): 4308.

https://doi.org/10.1182/blood.V118.21.4308.4308

Published: 2011

Journal Articles

Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine

Mamiko Sakata-Yanagimoto, Toru Sakai, Yasuyuki Miyake, Toshiki I. Saito, Haruhiko Maruyama, Yasuyuki Morishita, Etsuko Nakagami-Yamaguchi, Keiki Kumano, Hideo Yagita, Masashi Fukayama, Seishi Ogawa, Mineo Kurokawa, Koji Yasutomo, Shigeru Chiba

Blood (2011) 117 (1): 128–134.

https://doi.org/10.1182/blood-2010-07-289611

Published: 2011

Includes: Supplemental data

Journal Articles

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4 + Foxp3 + regulatory T cells in the establishment of oral tolerance

Tomohiro Fukaya, Hideaki Takagi, Yumiko Sato, Kaori Sato, Kawori Eizumi, Honami Taya, Tahiro Shin, Lieping Chen, Chen Dong, Miyuki Azuma, Hideo Yagita, Bernard Malissen, Katsuaki Sato

Blood (2010) 116 (13): 2266–2276.

https://doi.org/10.1182/blood-2009-10-250472

Published: 2010

Includes: Supplemental data

Journal Articles

Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration

Makiko Ohki, Yuichi Ohki, Makoto Ishihara, Chiemi Nishida, Yoshihiko Tashiro, Haruyo Akiyama, Hiromitsu Komiyama, Leif R. Lund, Atsumi Nitta, Kiyofumi Yamada, Zhenping Zhu, Hideoki Ogawa, Hideo Yagita, Ko Okumura, Hiromitsu Nakauchi, Zena Werb, Beate Heissig, Koichi Hattori

Blood (2010) 115 (21): 4302–4312.

https://doi.org/10.1182/blood-2009-08-236851

Published: 2010

Includes: Supplemental data

Journal Articles

The CD8 + memory T-cell state of readiness is actively maintained and reversible

Atef Allam, Dietrich B. Conze, Maria Letizia Giardino Torchia, Ivana Munitic, Hideo Yagita, Ryan T. Sowell, Amanda L. Marzo, Jonathan D. Ashwell

Blood (2009) 114 (10): 2121–2130.

https://doi.org/10.1182/blood-2009-05-220087

Published: 2009

Includes: Supplemental data

Journal Articles

Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus

Bhawna Poonia, Maria S. Salvato, Hideo Yagita, Toshihiro Maeda, Ko Okumura, C. David Pauza

Blood (2009) 114 (6): 1196–1204.

https://doi.org/10.1182/blood-2009-02-202655

Published: 2009

Journal Articles

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

Masafumi Nakayama, Hisaya Akiba, Kazuyoshi Takeda, Yuko Kojima, Masaaki Hashiguchi, Miyuki Azuma, Hideo Yagita, Ko Okumura

Blood (2009) 113 (16): 3821–3830.

https://doi.org/10.1182/blood-2008-10-185884

Published: 2009

Includes: Supplemental data

Journal Articles

Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

Shinsuke Yamanda, Satoru Ebihara, Masanori Asada, Tatsuma Okazaki, Kaijun Niu, Takae Ebihara, Akemi Koyanagi, Noriko Yamaguchi, Hideo Yagita, Hiroyuki Arai

Blood (2009) 113 (15): 3631–3639.

https://doi.org/10.1182/blood-2008-07-170381

Published: 2009

NARROW

PD-1 modulates regulatory T-cell homeostasis during low-dose interleukin-2 therapy

Programming of donor T cells using allogeneic δ-like ligand 4–positive dendritic cells to reduce GVHD in mice

PD-1 Signaling Has a Critical Role in Maintaining Regulatory T Cell Homeostasis; Implication for Treg Depletion Therapy By PD-1 Blockade

The Notch Ligand DLL4 Derived from Human Dendritic Cells Is Critical for Promoting T Helper (Th)1 and Th17 Cell Differentiation

Programming of Donor T Cells Using Allogeneic Delta-like Ligand 4-Positive Dendritic Cells to Reduce Gvhd but Retain GVL Activity

Enhanced Expression of PD-1 Modulates CD4+Foxp3+ Regulatory T Cell Homeostasis during Low-Dose IL-2 Therapy in Patients with Chronic Graft-Versus-Host Disease

Host Tissue PD-1 Pathway Contribute To Murine Chronic Graft-Versus-Host Disease Via Th1+Th17+ Cells

Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality

Identification of Previously Uncharacterized Delta 4-Positive Inflammatory Plasmacytoid Dendritic Cells That Play Important Roles in Eliciting Graft-Versus-Host Disease in Mice

Polyfunctional CD4 + T cells are essential for eradicating advanced B-cell lymphoma after chemotherapy

BCR-ABL Regulates Death Receptor Expression for TNF-Related Apoptosis-Inducing Ligand (TRAIL) in Philadelphia Chromosome-Positive Leukemia

Dll4 Blockade Modifies the Bone Marrow Vascular Niche and Improves Donor Bone Marrow Cells for Bone Marrow Transplant

Allogeneic Cytokine-Induced Killer Cells Kill Dendritic Cells Efficiently Resulting in Less Graft-Versus-Host Disease

Notch2 signaling is required for proper mast cell distribution and mucosal immunity in the intestine

Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4 + Foxp3 + regulatory T cells in the establishment of oral tolerance

Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration

The CD8 + memory T-cell state of readiness is actively maintained and reversible

Treatment with anti-FasL antibody preserves memory lymphocytes and virus-specific cellular immunity in macaques challenged with simian immunodeficiency virus

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

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American Society of Hematology

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American Society of Hematology

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