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Journal Articles

Platelet Subpopulations and Distinct Platelet Function Defects after Hematopoietic Stem Cell Transplantation in Mice and Humans

Kristina Mott, Lukas Johannes Weiss, Margret Droste, Maria Drayss, Sabrina Kraus, Torsten Steinbrunn, Harald Schulze

Blood (2023) 142 (Supplement 1): 348.

https://doi.org/10.1182/blood-2023-180641

Published: 2023

Journal Articles

Gradually Increased Gpiib/Iiia Responsiveness from Preterm and Term Neonatal Infants to Adults Reveals a Complex Phenotypic Switch during Platelet Ontogenesis - Data from the Platelets in Neonatal Infants Study (PLINIUS)

Oliver Andres, Lukas J. Weiß, Maria Drayss, Kristina Mott, Christoph Haertel, Christian P. Speer, Harald Schulze

Blood (2022) 140 (Supplement 1): 2639–2640.

https://doi.org/10.1182/blood-2022-169481

Published: 2022

Journal Articles

Mixed Bone Marrow Chimerism after Murine Stem Cell Transplantation Results in Distinct Platelet Subpopulations with Opposing Responsiveness

Kristina Mott, Margret Droste, Lukas J. Weiß, Harald Schulze

Blood (2022) 140 (Supplement 1): 2900–2901.

https://doi.org/10.1182/blood-2022-166053

Published: 2022

Journal Articles

Acquired platelet GPVI receptor dysfunction in critically ill patients with sepsis

Lukas J. Weiss, Georgi Manukjan, Annerose Pflug, Nadine Winter, Mathis Weigel, Nils Nagler, Markus Kredel, Thiên-Trí Lâm, Bernhard Nieswandt, Dirk Weismann, Harald Schulze

Blood (2021) 137 (22): 3105–3115.

https://doi.org/10.1182/blood.2020009774

Published: 2021

Includes: Supplemental data

Journal Articles

Antibody-induced procoagulant platelets in severe COVID-19 infection

Karina Althaus, Irene Marini, Jan Zlamal, Lisann Pelzl, Anurag Singh, Helene Häberle, Martin Mehrländer, Stefanie Hammer, Harald Schulze, Michael Bitzer, Nisar Malek, Dominik Rath, Hans Bösmüller, Bernard Nieswandt, Meinrad Gawaz, Tamam Bakchoul, Peter Rosenberger

Blood (2021) 137 (8): 1061–1071.

https://doi.org/10.1182/blood.2020008762

Published: 2021

Includes: Supplemental data

Journal Articles

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Blood (2019) 134 (21): 1847–1858.

https://doi.org/10.1182/blood.2019000185

Published: 2019

Includes: Multimedia, Supplemental data

Journal Articles

Acquired Platelet GPVI Dysfunction As Possible Predictor for Early Sepsis Diagnosis and Poor Outcome

Lukas J Weiss, Georgi Manukjan, PhD, Nils Nagler, Markus Kredel, MD, Thien-Tri Lam, MD, Bernhard Nieswandt, PhD, Dirk Weismann, MD, Harald Schulze, PhD

Blood (2019) 134 (Supplement_1): 3609.

https://doi.org/10.1182/blood-2019-131088

Published: 2019

Journal Articles

Spatial Regulation of Thrombopoiesis in the Bone Marrow

David Stegner, PhD, Judith van Eeuwijk, PhD, Maximilian G Gorelashvili, Oguzhan Angay, Mike Friedrich, Jürgen Pinnecker, Patrick Schmithausen, Daniela Semeniak, PhD, Harald Schulze, PhD, Christian Brede, PhD, Andreas Beilhack, MD, Bernhard Nieswandt, PhD, Katrin G Heinze

Blood (2018) 132 (Supplement 1): SCI-23.

https://doi.org/10.1182/blood-2018-99-109545

Published: 2018

Journal Articles

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Blood (2017) 130 (25): 2774–2785.

https://doi.org/10.1182/blood-2017-05-784413

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Distinct HLA-DPB1 Matching of Unrelated Donors for Malignant and Non-Malignant Indications Is Critical in Pediatric Hematopoietic Stem Cell Transplantation

Kremena Todorova, MD, Verena Wiegering, MD, Gabriele Strauss, MD, Matthias K. Eyrich, MD, Maximilian Gorelashvili, Viktoria Buck, Sebstian Voigt, MD, Joern-Sven Kuehl, MD, Wolfram Ebell, MD, Harald Schulze, PhD

Blood (2017) 130 (Supplement 1): 3321.

https://doi.org/10.1182/blood.V130.Suppl_1.3321.3321

Published: 2017

Journal Articles

An Autosomal-Recessive GFI1B Mutation Defines the Splice Isoform p37 As Essential for Biogenesis of Functional Human Platelets, but Dispensable for Erythropoiesis

Harald Schulze, PhD, Axel Schlagenhauf, PhD, Georgi Manukjan, PhD, Christine Beham-Schmid, MD, Oliver Andres, MD, Eva Klopocki, PhD, Eva-Maria König, Harald Haidl, MD, Simon Panzer, MD, Karina Althaus, MD, Wolfgang Muntean, MD, Wolfgang Schwinger, MD, Christian E. Urban, MD, Andreas Greinacher, MD, Tamam Bakchoul, MD, Markus Seidel, MD

Blood (2016) 128 (22): 2644.

https://doi.org/10.1182/blood.V128.22.2644.2644

Published: 2016

Journal Articles

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Simon Stritt, Markus Bender, Paquita Nurden, MD PhD, Judith van Eeuwijk, Barbara Zieger, Prof, Karim Kentouche, MD, Harald Schulze, Prof, Henner Morbach, MD, David Stegner, PhD, Katrin G Heinze, PhD, Sebastian Dütting, PhD, Shuchi Gupta, PhD, Walter Witke, Prof, Hervé Falet, PhD, Alain Fischer, Prof, John H. Hartwig, Prof, Bernhard Nieswandt, Prof

Blood (2014) 124 (21): 4200.

https://doi.org/10.1182/blood.V124.21.4200.4200

Published: 2014

Journal Articles

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

Irina Pleines, Sebastian Dütting, Deya Cherpokova, Anita Eckly, Imke Meyer, Martina Morowski, Georg Krohne, Harald Schulze, Christian Gachet, Najet Debili, Cord Brakebusch, Bernhard Nieswandt

Blood (2013) 122 (18): 3178–3187.

https://doi.org/10.1182/blood-2013-03-487942

Published: 2013

Includes: Supplemental data

Journal Articles

In Vivo Platelet Production Occurs from an Expanding Pool of Non-Apoptotic Megakaryocytes in a Mouse Model of Passive Immune Thrombocytopenia

Harald Schulze, PhD, Silke Schwiebert, Kathrin Roth, Oliver Meyer, Gabriele Strauss, Anja E Hauser, Imke Meyer

Blood (2012) 120 (21): 1214.

https://doi.org/10.1182/blood.V120.21.1214.1214

Published: 2012

Journal Articles

Effect of Single Nucleotide Polymorphism in the Gene RBM8A Together with the Microdeletion 1q21 in Thrombocytopenia-Absent Radii Syndrome.

Harald Schulze, PhD, Cornelis A Albers, Gabriele Strauss, Janine Fiedler, Markus Schmugge, Willem H Ouwehand, Kathleen Freson, Ruth Newbury-Ecob, Cedric Ghaevert, PhD

Blood (2012) 120 (21): 2372.

https://doi.org/10.1182/blood.V120.21.2372.2372

Published: 2012

Journal Articles

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10

Imke Meyer, Stefan Kunert, Silke Schwiebert, Ina Hagedorn, Joseph E. Italiano, Jr, Sebastian Dütting, Bernhard Nieswandt, Sebastian Bachmann, Harald Schulze

Blood (2012) 120 (17): 3594–3602.

https://doi.org/10.1182/blood-2012-01-401737

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

The Abrogated Thrombopoietin (TPO) Signal Transduction In Pediatric Patients Suffering From Thrombocytopenia-Absent Radii Syndrome Is Restored In Adult Patients, Suggesting An Additional, c-Mpl-Jak2-Independent Mechanism for Platelet Biogenesis.

Janine Fiedler, Gabriele Strauss, Martin Wannack, Silke Fleischhauer, Kerstin Seidel, Eva Klopocki, Stefan Mundlos, Markus Schmugge, MD, Harald Schulze, PhD

Blood (2010) 116 (21): 1561.

https://doi.org/10.1182/blood.V116.21.1561.1561

Published: 2010

Journal Articles

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow

Oliver Winter, Katrin Moser, Elodie Mohr, Dimitra Zotos, Henriette Kaminski, Martin Szyska, Katrin Roth, David M. Wong, Christof Dame, David M. Tarlinton, Harald Schulze, Ian C. M. MacLennan, Rudolf A. Manz

Blood (2010) 116 (11): 1867–1875.

https://doi.org/10.1182/blood-2009-12-259457

Published: 2010

Includes: Supplemental data

Journal Articles

The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation

Stefan Kunert, Imke Meyer, Silke Fleischhauer, Martin Wannack, Janine Fiedler, Ramesh A. Shivdasani, Harald Schulze

Blood (2009) 114 (27): 5532–5540.

https://doi.org/10.1182/blood-2009-04-216804

Published: 2009

Includes: Supplemental data

Journal Articles

The beta1-Tubulin Binding Protein RanBP10 Plays a Critical Role for Platelet Discoid Shape and Hemostasis

Harald Schulze, PhD, Silke Fleischhauer, Imke Meyer, Martin Wannack, Stefan Kunert

Blood (2008) 112 (11): 414.

https://doi.org/10.1182/blood.V112.11.414.414

Published: 2008

NARROW

Platelet Subpopulations and Distinct Platelet Function Defects after Hematopoietic Stem Cell Transplantation in Mice and Humans

Gradually Increased Gpiib/Iiia Responsiveness from Preterm and Term Neonatal Infants to Adults Reveals a Complex Phenotypic Switch during Platelet Ontogenesis - Data from the Platelets in Neonatal Infants Study (PLINIUS)

Mixed Bone Marrow Chimerism after Murine Stem Cell Transplantation Results in Distinct Platelet Subpopulations with Opposing Responsiveness

Acquired platelet GPVI receptor dysfunction in critically ill patients with sepsis

Antibody-induced procoagulant platelets in severe COVID-19 infection

Pivotal role of PDK1 in megakaryocyte cytoskeletal dynamics and polarization during platelet biogenesis

Acquired Platelet GPVI Dysfunction As Possible Predictor for Early Sepsis Diagnosis and Poor Outcome

Spatial Regulation of Thrombopoiesis in the Bone Marrow

CK2β regulates thrombopoiesis and Ca 2+ -triggered platelet activation in arterial thrombosis

Distinct HLA-DPB1 Matching of Unrelated Donors for Malignant and Non-Malignant Indications Is Critical in Pediatric Hematopoietic Stem Cell Transplantation

An Autosomal-Recessive GFI1B Mutation Defines the Splice Isoform p37 As Essential for Biogenesis of Functional Human Platelets, but Dispensable for Erythropoiesis

Aberrant Microtubule Organization and Wiskott-Aldrich Syndrome-like Defects in Platelets and Megakaryocytes of Profilin1-Deficient Mice

Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42

In Vivo Platelet Production Occurs from an Expanding Pool of Non-Apoptotic Megakaryocytes in a Mouse Model of Passive Immune Thrombocytopenia

Effect of Single Nucleotide Polymorphism in the Gene RBM8A Together with the Microdeletion 1q21 in Thrombocytopenia-Absent Radii Syndrome.

Altered microtubule equilibrium and impaired thrombus stability in mice lacking RanBP10

The Abrogated Thrombopoietin (TPO) Signal Transduction In Pediatric Patients Suffering From Thrombocytopenia-Absent Radii Syndrome Is Restored In Adult Patients, Suggesting An Additional, c-Mpl-Jak2-Independent Mechanism for Platelet Biogenesis.

Megakaryocytes constitute a functional component of a plasma cell niche in the bone marrow

The microtubule modulator RanBP10 plays a critical role in regulation of platelet discoid shape and degranulation

The beta1-Tubulin Binding Protein RanBP10 Plays a Critical Role for Platelet Discoid Shape and Hemostasis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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