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Journal Articles

Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell–like blasts in KMT2A -rearranged leukemia

Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, James W. Davenport, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P. Hunger, Carolyn A. Felix, Hao Wu, Patrick A. Brown, Erin M. Guest, David M. Barrett, Kathrin M. Bernt, Kai Tan
Journal: Blood
Blood (2022) 139 (14): 2198–2211.
DOI: https://doi.org/10.1182/blood.2021013442
Published: 2022
Includes: Supplemental data
Journal Articles

Single-Cell Multiomics Reveals Increased Plasticity, Resistant Populations and Stem-Cell-like Blasts in KMT2A-Rearranged Leukemia

Changya Chen, Wenbao Yu, Fatemeh Alikarami, Qi Qiu, Chia-hui Chen, Jennifer Flournoy, Peng Gao, Yasin Uzun, Li Fang, Yuxuan Hu, Qin Zhu, Kai Wang, Clara Libbrecht, Alex Felmeister, Isaiah Rozich, Yang-yang Ding, Stephen P Hunger, Hao Wu, Patrick A. Brown, Erin Guest, David M Barrett, Kathrin M. Bernt, Kai Tan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2203.
DOI: https://doi.org/10.1182/blood-2021-146102
Published: 2021
Journal Articles

BCL10 Gain-of-Function Mutations Aberrantly Induce Canonical and Non-Canonical NF-Kb Activation and Resistance to Ibrutinib in ABC-DLBCL

Min Xia, Liron David, PhD, Matthew Teater, PhD, Ozlem Onder, PhD MSc, Kojo S. J. Elenitoba-Johnson, MD, Lorena Fontan, PhD, Hao Wu, PhD, Ari Melnick, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
DOI: https://doi.org/10.1182/blood-2020-141363
Published: 2020
Journal Articles

CRISPR/dCas9 (D10A) -Mediated Hb CS Gene Editing and Identification of Genetically Modified Fibroblasts

Lian Yu, Wei Hao Wu, WANG Shunqing, Ken H. Young, Funeng Jiang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5754.
DOI: https://doi.org/10.1182/blood-2019-129931
Published: 2019
Journal Articles

Chemically Induced Degradation of MALT1 to Treat B-Cell Lymphomas

Lorena Fontan, PhD, John Hatcher, PhD, David Scott, Qi Qiao, Ilkay Us, Guangyan Du, Matthew Durant, Jimmy Wilson, Hao Wu, PhD, Nathanael Gray, Ari Melnick, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2073.
DOI: https://doi.org/10.1182/blood-2019-130666
Published: 2019
Journal Articles

Low-Dose Interleukin-2 Restores Human Regulatory T Cell Function, in Vitro , As a Potential in the Handle of Graft Versus Host Disease (GvHD)

Tzeon-Jye Chiou, MD, Hsiu-Hsia Lin, PhD, Wei-Hao Wu, BS, Jhih-Yun Jian, MS, Sin-Tak Chu, PhD, Woan-Fang Tzeng, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5450.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.5450.5450
Published: 2017
Journal Articles

Expansion and Reactivation of Human Naïve T-Cells Transition into CD4+CD25+FoxP3+CD127-Regulatory T Cells, In Vitro , for the Potential Use of Graft-Versus-Host Disease Prevention

Tzeon-Jye Chiou, MD, Tien-Hua Chu, PhD, Wei-Hao Wu, MS, Sin-Tak Chu, PhD, Woan-Fang Tzeng, PhD
Journal: Blood
Blood (2016) 128 (22): 5729.
DOI: https://doi.org/10.1182/blood.V128.22.5729.5729
Published: 2016
Journal Articles

Calvariae-Resident Osteomacs That Are Phenotypically and Functionally Distinct from Marrow-Derived Macrophages Interact with Megakaryocytes to Regulate Hematopoietic Stem Cell Function

Safa F Mohamad, Linlin Xu, Himes R Evan, Hao Wu, Marta Alvarez, Paul Childress, Korbin Davis, Melissa Kacena, Edward F. Srour, PhD
Journal: Blood
Blood (2016) 128 (22): 28.
DOI: https://doi.org/10.1182/blood.V128.22.28.28
Published: 2016
Journal Articles

CD166 Identifies Multiple Myeloma Cells That Preferentially Home to the Bone Marrow Microenvironment and Promote Disease Progression and Bone Lytic Disease

Linlin Xu, Christophe Machal, Hao Wu, Colin D Crean, Bradley Poteat, Angelo A. Cardoso, Helmut Hanenberg, Khalid Mohammad, Attaya Suvannasankha, Edward F Srour
Journal: Blood
Blood (2014) 124 (21): 174.
DOI: https://doi.org/10.1182/blood.V124.21.174.174
Published: 2014
Journal Articles

A Novel Mutation In Bruton Tyrosine Kinase Confers Acquired Resistance To Ibrutinib (PCI-32765) In CLL

Richard R. Furman, MD, Shuhua Cheng, PhD, Pin Lu, MD, PhD, Menu Setty, Alexandar Perez, Ailin Guo, MD, PhD, Joelle Racchumi, BS, Jiao Ma, PhD, Morton Coleman, MD, Kabaleeswaran Venkataraman, PhD, Guozhou Xu, PhD, Wei Chen, PhD, Hao Wu, PhD, Betty Y. Chang, PhD, Christina Leslie, PhD, Y. Lynn Wang, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 4914.
DOI: https://doi.org/10.1182/blood.V122.21.4914.4914
Published: 2013
Journal Articles

Role Of CD166 In Multiple Myeloma Cell Homing To The Bone Marrow Microenvironment and Disease Progression

Linlin Xu, Christophe Machal, Hao Wu, Bradley Poteat, Colin D. Crean, Angelo A. Cardoso, MD, PhD, John M Chirgwin, PhD, Helmut Hanenberg, MD, Khalid S. Mohammad, M.D. Ph.D., Attaya Suvannasankha, MD, Edward F Srour, PhD
Journal: Blood
Blood (2013) 122 (21): 3102.
DOI: https://doi.org/10.1182/blood.V122.21.3102.3102
Published: 2013
Journal Articles

Extensive HLA-driven viral diversity following a narrow-source HIV-1 outbreak in rural China

Tao Dong, Yonghong Zhang, Ke Yi Xu, Huiping Yan, Ian James, Yanchun Peng, Marie-Eve Blais, Silvana Gaudieri, Xinyue Chen, Wenhui Lun, Hao Wu, Wen Yan Qu, Tim Rostron, Ning Li, Yu Mao, Simon Mallal, Xiaoning Xu, Andrew McMichael, Mina John, Sarah L. Rowland-Jones
Journal: Blood
Blood (2011) 118 (1): 98–106.
DOI: https://doi.org/10.1182/blood-2010-06-291963
Published: 2011
Includes: Supplemental data
Journal Articles

PD-1 up-regulation is correlated with HIV-specific memory CD8 + T-cell exhaustion in typical progressors but not in long-term nonprogressors

Clinical Trials & Observations
Ji-Yuan Zhang, Zheng Zhang, Xicheng Wang, Jun-Liang Fu, Jinxia Yao, Yanmei Jiao, Liangen Chen, Hui Zhang, Jianan Wei, Lei Jin, Ming Shi, George Fu Gao, Hao Wu, Fu-Sheng Wang
Journal: Blood
Blood (2007) 109 (11): 4671–4678.
DOI: https://doi.org/10.1182/blood-2006-09-044826
Published: 2007