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Journal Articles

How I treat bleeding in hereditary hemorrhagic telangiectasia

Hanny Al-Samkari

Blood (2024) 144 (9): 940–954.

https://doi.org/10.1182/blood.2023021765

Published: 2024

Journal Articles

PATH-HHT, a Double-Blind, Randomized, Placebo-Controlled Trial in Hereditary Hemorrhagic Telangiectasia Demonstrates That Pomalidomide Reduces Epistaxis and Improves Quality of Life

Blood (2023) 142 (Supplement 2): LBA-3.

https://doi.org/10.1182/blood-2023-191983

Published: 2023

Journal Articles

Mitapivat Treatment Reduces Levels of Interference in Work/School Activity for Adult Patients with Pyruvate Kinase Deficiency

Jennifer A Rothman, Parija Patel, Jing Zhao, Susan Morris, Junlong Li, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 2365.

https://doi.org/10.1182/blood-2023-180697

Published: 2023

Journal Articles

Improvements in Markers of Hemolysis and Liver Iron Concentration in Mitapivat-Treated Adult Patients with a Delayed Hemoglobin Response

Eduard J. Van Beers, Bryan McGee, Rengyi Xu, Melissa Dibacco, Kevin H.M. Kuo, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 5226.

https://doi.org/10.1182/blood-2023-186533

Published: 2023

Journal Articles

Hereditary Hemorrhagic Telangiectasia May be the Most Clinically Significant and Morbid Inherited Bleeding Disorder of Women

Ellen Zhang, Zain Virk, Josanna Rodriguez-Lopez, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 28.

https://doi.org/10.1182/blood-2023-187772

Published: 2023

Journal Articles

Interactive Case-Based Education on Pyruvate Kinase Deficiency Improves Hematologists' Competence in Implementing the Latest Diagnostic and Management Approaches

S Christy Rohani-Montez, Sanneke Koekkoek, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 7227.

https://doi.org/10.1182/blood-2023-175039

Published: 2023

Journal Articles

Longitudinal Systemic Bevacizumab Therapy Produces Cost Savings and Improves Quality-Adjusted Life Expectancy in the Care of Patients with Hereditary Hemorrhagic Telangiectasia with Moderate-to-Severe Bleeding

Daniel Wang, Satoko Ito, Christina Waldron, Ayesha Butt, Ellen Zhang, Harlan M. Krumholz, Hanny Al-Samkari, George Goshua

Blood (2023) 142 (Supplement 1): 2312.

https://doi.org/10.1182/blood-2023-185340

Published: 2023

Journal Articles

Ianalumab, a Novel Anti-B-Cell Activating Factor (BAFF) Receptor (BAFF-R) Monoclonal Antibody (mAb) in Development for Immune Thrombocytopenia (ITP) and Warm Autoimmune Hemolytic Anemia (wAIHA), Has Demonstrated a Favorable Safety Profile in Sjögren's Syndrome (SjS), Systemic Lupus Erythematosus (SLE) and Chronic Lymphocytic Leukemia (CLL)

Adam Cuker, Hanny Al-Samkari, Wilma Barcellini, Nichola Cooper, Waleed Ghanima, Marc Michel, Raymond SM Wong, Francesco Zaja, Fengkui Zhang, Patrick Urban, Roberto Abi Rached, David J Kuter

Blood (2023) 142 (Supplement 1): 5427.

https://doi.org/10.1182/blood-2023-180055

Published: 2023

Journal Articles

Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling Parameters

Kevin H.M. Kuo, Sylvia Titi Singer, Gershwin Theophilus Blyden, Lanetta Bronté-Hall, Aidan Faller, Abdullah Kutlar, Frans A. Kuypers, Aliya U. Zaidi, Patrick C. Hines, Niren Patel, Sandra Larkin, Hanny Al-Samkari, Sujit Sheth, Seyed Mehdi Nouraie, Susan Perrine

Blood (2023) 142 (Supplement 1): 1148.

https://doi.org/10.1182/blood-2023-184627

Published: 2023

Journal Articles

Impact of Degree and Duration of Iron Overload on Incidence of Diabetes Mellitus, Cardiac Disease, and Death in Congenital Hemolytic Anemias

Aaron Cheng, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 1094.

https://doi.org/10.1182/blood-2023-179640

Published: 2023

Journal Articles

A Phase III Clinical Trial Program Investigating the Efficacy and Safety of Ianalumab in Patients with Primary Immune Thrombocytopenia (VAYHIT1 and VAYHIT2) and Warm Autoimmune Hemolytic Anemia (VAYHIA)

Hanny Al-Samkari, Wilma Barcellini, Nichola Cooper, Waleed Ghanima, Marc Michel, Raymond SM Wong, Francesco Zaja, Fengkui Zhang, Patrick Urban, Alex Allepuz, Justyna Fronczek-Sokol, Jens Haenig, Pascal Edrich, Adam Cuker

Blood (2023) 142 (Supplement 1): 5456.

https://doi.org/10.1182/blood-2023-180647

Published: 2023

Journal Articles

Time to Achieve Platelet Count Response after Intravenous Efgartigimod in Adults with Primary Immune Thrombocytopenia: A Phase 3, Multicenter, Double-Blinded, Placebo-Controlled, Randomized Clinical Trial (ADVANCE IV)

Catherine M. Broome, Vickie McDonald, Yoshitaka Miyakawa, Monica Carpenedo, David J Kuter, Hanny Al-Samkari, James B. Bussel, Anna Hultberg, Filip Matthijssens, Jaume Ayguasanosa, Kristof De Beuf, Francesco Rodeghiero, Marc Michel, Adrian Newland

Blood (2023) 142 (Supplement 1): 689.

https://doi.org/10.1182/blood-2023-189125

Published: 2023

Journal Articles

A Novel Online Decision Support Tool to Determine Practice Patterns and Concordance with Experts in the Treatment of Patients with Immune Thrombocytopenia

Jacqueline L. Olin, Catherine M. Broome, Sandhya R Panch, Kristen Rosenthal, Timothy A. Quill, Kristin A. Shimano, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 5046.

https://doi.org/10.1182/blood-2023-182029

Published: 2023

Journal Articles

Avatrombopag for Adults with Early Versus Chronic Immune Thrombocytopenia

Zain Virk, Rebecca Karp Leaf, David J Kuter, Katayoon Goodarzi, Nathan T. Connell, Jean M. Connors, Hanny Al-Samkari

Blood (2023) 142 (Supplement 1): 392.

https://doi.org/10.1182/blood-2023-179601

Published: 2023

Journal Articles

Long-term risk of developing immune thrombocytopenia and hematologic neoplasia in adults with mild thrombocytopenia

Nardeen Ayad, Rachael F. Grace, David J. Kuter, Hanny Al-Samkari

Blood (2022) 140 (26): 2849–2852.

https://doi.org/10.1182/blood.2022016757

Published: 2022

Includes: Supplemental data

Journal Articles

Mitapivat Improves Iron Overload in Patients with Pyruvate Kinase Deficiency

Eduard J. van Beers, Hanny Al-Samkari, Rachael F. Grace, Wilma Barcellini, Andreas Glenthøj, Melissa Dibacco, Penelope A. Kosinski, Emily Xu, Vanessa Beynon, Parija Patel, John B. Porter, Kevin H.M. Kuo

Blood (2022) 140 (Supplement 1): 2460–2462.

https://doi.org/10.1182/blood-2022-169098

Published: 2022

Journal Articles

Long-Term Improvements in Patient-Reported Outcomes in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat

Kevin H.M. Kuo, Rachael F. Grace, Eduard J. van Beers, Wilma Barcellini, Andreas Glenthøj, Susanne Holzhauer, Parija Patel, Vanessa Beynon, Junlong Li, Erin Zagadailov, Hanny Al-Samkari

Blood (2022) 140 (Supplement 1): 1223–1225.

https://doi.org/10.1182/blood-2022-168954

Published: 2022

Journal Articles

A Phase 2a/2b Multicenter Study of AG-946 in Patients with Anemia Due to Lower-Risk Myelodysplastic Syndromes

Hanny Al-Samkari, Pierre Fenaux, Mikkael A. Sekeres, Eytan Stein, David A. Sallman, Andrew M. Brunner, Xiaoshu D. Gurov, Ophelia Yin, Meghan Frisbie, James Xiao, Joy Bhatia, Vanessa Beynon, Megan Wind-Rotolo, Melissa Dibacco, Uwe Platzbecker

Blood (2022) 140 (Supplement 1): 4076–4078.

https://doi.org/10.1182/blood-2022-168907

Published: 2022

Journal Articles

A Multicenter Study of Safety, Tolerability, and Effectiveness of Antithrombotic Therapy in Hereditary Hemorrhagic Telangiectasia

Zain M Virk, Ellen Zhang, Josanna Rodriguez-Lopez, Alison Witkin, Alexandra Wong, Jay Luther, Angela Lin, Mingming Ning, Eric F. Grabowski, Eric Holbrook, Hanny Al-Samkari

Blood (2022) 140 (Supplement 1): 1418–1419.

https://doi.org/10.1182/blood-2022-164655

Published: 2022

Journal Articles

A Machine-Learning Derived Red Blood Cell Morphology Tool Enables Differential Diagnosis and Novel Single-Cell Analyses

Brody Foy, Jonathan Stefely, Pavan K. Bendapudi, Robert P. Hasserjian, Hanny Al-Samkari, Abner Louissaint, Jr., Megan J Fitzpatrick, Bailey Hutchison, Christopher Mow, Julia Collins, Hasmukh P. Patel, Chhaya Patel, Nikita Patel, Samantha Ho, Richard M Kaufman, Walter Dzik, John M. Higgins, Robert S Makar

Blood (2022) 140 (Supplement 1): 10704–10705.

https://doi.org/10.1182/blood-2022-170422

Published: 2022

NARROW

How I treat bleeding in hereditary hemorrhagic telangiectasia

PATH-HHT, a Double-Blind, Randomized, Placebo-Controlled Trial in Hereditary Hemorrhagic Telangiectasia Demonstrates That Pomalidomide Reduces Epistaxis and Improves Quality of Life

Mitapivat Treatment Reduces Levels of Interference in Work/School Activity for Adult Patients with Pyruvate Kinase Deficiency

Improvements in Markers of Hemolysis and Liver Iron Concentration in Mitapivat-Treated Adult Patients with a Delayed Hemoglobin Response

Hereditary Hemorrhagic Telangiectasia May be the Most Clinically Significant and Morbid Inherited Bleeding Disorder of Women

Interactive Case-Based Education on Pyruvate Kinase Deficiency Improves Hematologists' Competence in Implementing the Latest Diagnostic and Management Approaches

Longitudinal Systemic Bevacizumab Therapy Produces Cost Savings and Improves Quality-Adjusted Life Expectancy in the Care of Patients with Hereditary Hemorrhagic Telangiectasia with Moderate-to-Severe Bleeding

Initial Results in a Phase 1b Trial of PB-04 in Sickle Cell Disease Demonstrate Fetal Hemoglobin Induction, Additive Activity with Hydroxyurea, and Improved Red Blood Cell Sickling Parameters

Impact of Degree and Duration of Iron Overload on Incidence of Diabetes Mellitus, Cardiac Disease, and Death in Congenital Hemolytic Anemias

A Phase III Clinical Trial Program Investigating the Efficacy and Safety of Ianalumab in Patients with Primary Immune Thrombocytopenia (VAYHIT1 and VAYHIT2) and Warm Autoimmune Hemolytic Anemia (VAYHIA)

Time to Achieve Platelet Count Response after Intravenous Efgartigimod in Adults with Primary Immune Thrombocytopenia: A Phase 3, Multicenter, Double-Blinded, Placebo-Controlled, Randomized Clinical Trial (ADVANCE IV)

A Novel Online Decision Support Tool to Determine Practice Patterns and Concordance with Experts in the Treatment of Patients with Immune Thrombocytopenia

Avatrombopag for Adults with Early Versus Chronic Immune Thrombocytopenia

Long-term risk of developing immune thrombocytopenia and hematologic neoplasia in adults with mild thrombocytopenia

Mitapivat Improves Iron Overload in Patients with Pyruvate Kinase Deficiency

Long-Term Improvements in Patient-Reported Outcomes in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat

A Phase 2a/2b Multicenter Study of AG-946 in Patients with Anemia Due to Lower-Risk Myelodysplastic Syndromes

A Multicenter Study of Safety, Tolerability, and Effectiveness of Antithrombotic Therapy in Hereditary Hemorrhagic Telangiectasia

A Machine-Learning Derived Red Blood Cell Morphology Tool Enables Differential Diagnosis and Novel Single-Cell Analyses

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American Society of Hematology

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ASH Publications

American Society of Hematology

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