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Journal Articles

High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95

Anja Troeger, Ludmila Glouchkova, Birgit Ackermann, Gabriele Escherich, Roland Meisel, Helmut Hanenberg, Monique L. den Boer, Rob Pieters, Gritta E. Janka-Schaub, Ulrich Goebel, Hans-Juergen Laws, Dagmar Dilloo

Blood (2008) 112 (4): 1028–1034.

https://doi.org/10.1182/blood-2007-11-123315

Published: 2008

Journal Articles

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia

James B. Nachman, Nyla A. Heerema, Harland Sather, Bruce Camitta, Erik Forestier, Christine J. Harrison, Nicole Dastugue, Martin Schrappe, Ching-Hon Pui, Giuseppe Basso, Lewis B. Silverman, Gritta E. Janka-Schaub

Blood (2007) 110 (4): 1112–1115.

https://doi.org/10.1182/blood-2006-07-038299

Published: 2007

Journal Articles

Up-regulation of c-FLIP S+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL

Anja Troeger, Ingo Schmitz, Meinolf Siepermann, Ludmila Glouchkova, Ulrike Gerdemann, Gritta E. Janka-Schaub, Klaus Schulze-Osthoff, Dagmar Dilloo

Blood (2007) 110 (1): 384–387.

https://doi.org/10.1182/blood-2006-08-038398

Published: 2007

Journal Articles

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols

Amy Holleman, Monique L. den Boer, Meyling H. Cheok, Karin M. Kazemier, Deqing Pei, James R. Downing, Gritta E. Janka-Schaub, Ulrich Göbel, Ulrike B. Graubner, Ching-Hon Pui, William E. Evans, Rob Pieters

Blood (2006) 108 (6): 1984–1990.

https://doi.org/10.1182/blood-2006-04-015990

Published: 2006

Journal Articles

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

Amy Holleman, Monique L. den Boer, Renée X. de Menezes, Meyling H. Cheok, Cheng Cheng, Karin M. Kazemier, Gritta E. Janka-Schaub, Ulrich Göbel, Ulrike B. Graubner, William E. Evans, Rob Pieters

Blood (2006) 107 (2): 769–776.

https://doi.org/10.1182/blood-2005-07-2930

Published: 2006

Includes: Supplemental data

Journal Articles

Assessment of the Aryl Hydrocarbon Receptor Gene as a Therapeutic Target in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Marrit Meier, MSc, Monique L. den Boer, PhD, Mathilde J.C. Broekhuis, BSc, Ronald W. Stam, MSc, Elisabeth R. van Wering, PhD, Gritta E. Janka-Schaub, PhD, Rob Pieters, MD, PhD

Blood (2005) 106 (11): 536.

https://doi.org/10.1182/blood.V106.11.536.536

Published: 2005

Journal Articles

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia

Amy Holleman, Monique L. den Boer, Karin M. Kazemier, H. Berna Beverloo, Anne R. M. von Bergh, Gritta E. Janka-Schaub, Rob Pieters

Blood (2005) 106 (5): 1817–1823.

https://doi.org/10.1182/blood-2004-11-4296

Published: 2005

Journal Articles

Asparagine synthetase expression is linked with l-asparaginase resistance in TEL-AML1–negative but not TEL-AML1–positive pediatric acute lymphoblastic leukemia

Wendy A. G. Stams, Monique L. den Boer, Amy Holleman, Inge M. Appel, H. Berna Beverloo, Elisabeth R. van Wering, Gritta E. Janka-Schaub, William E. Evans, Rob Pieters

Blood (2005) 105 (11): 4223–4225.

https://doi.org/10.1182/blood-2004-10-3892

Published: 2005

Journal Articles

Sensitivity and Cross-Resistance to Deoxynucleoside Analogs in Childhood Acute Leukemia.

Gertjan J. Kaspers, Isabelle Hubeek, Christian M. Zwaan, Monique L. Den Boer, Gritta E. Janka-Schaub, Elisabeth R. Van Wering, Brenda E. Gibson, Ursula Creutzig, Godefridus J. Peters

Blood (2004) 104 (11): 2086.

https://doi.org/10.1182/blood.V104.11.2086.2086

Published: 2004

Journal Articles

Germ-Line Genetic Variations in TP53 and Risk for Pediatric Acute Lymphoblastic Leukemia.

Toralf Bernig, MD, Laurie Burdette, PhD, Thomas Lehrnbecher, MD, Ulrike B. Graubner, MD, Monique L. den Boer, MD, Rob Pieters, MD, Gritta E. Janka-Schaub, MD, Stephen J. Chanock, MD

Blood (2004) 104 (11): 1890.

https://doi.org/10.1182/blood.V104.11.1890.1890

Published: 2004

Journal Articles

Genetic Variants of Ataxia Telangiectasia Mutated ( ATM ) and Susceptibility for Childhood T-Lineage Acute Lymphoblastic Leukemia.

Marrit Meier, MSc, Monique L. Den Boer, PhD, Andrew G. Hall, MD, PhD, Julie Irving, PhD, Monique Passier, BSc, Lynne Minto, BSc, Elisabeth R. Van Wering, Gritta E. Janka-Schaub, Rob Pieters, MD, PhD

Blood (2004) 104 (11): 1892.

https://doi.org/10.1182/blood.V104.11.1892.1892

Published: 2004

Journal Articles

Expression of P73 Splice Variants Correlates to Resistance to DNA Damaging Drugs in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Marrit Meier, MSc, Monique L. Den Boer, PhD, Jules P.P. Meijerink, PhD, Monique Passier, BSc, Elisabeth R. Van Wering, Gritta E. Janka-Schaub, Rob Pieters, MD, PhD

Blood (2004) 104 (11): 995.

https://doi.org/10.1182/blood.V104.11.995.995

Published: 2004

Journal Articles

Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia

Amy Holleman, Monique L. den Boer, Karin M. Kazemier, Gritta E. Janka-Schaub, Rob Pieters

Blood (2003) 102 (13): 4541–4546.

https://doi.org/10.1182/blood-2002-11-3612

Published: 2003

Journal Articles

Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92

Dörthe O. Harms, Ulrich Göbel, Hans J. Spaar, Ulrike B. Graubner, Norbert Jorch, Peter Gutjahr, Gritta E. Janka-Schaub, for the COALL Study Group

Blood (2003) 102 (8): 2736–2740.

https://doi.org/10.1182/blood-2002-08-2372

Published: 2003

Journal Articles

Sensitivity to l-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+pediatric ALL

Wendy A. G. Stams, Monique L. den Boer, H. Berna Beverloo, Jules P. P. Meijerink, Rolinda L. Stigter, Elisabeth R. van Wering, Gritta E. Janka-Schaub, Rosalyn Slater, Rob Pieters

Blood (2003) 101 (7): 2743–2747.

https://doi.org/10.1182/blood-2002-08-2446

Published: 2003

Journal Articles

Differential mRNA expression of Ara-C–metabolizing enzymes explains Ara-C sensitivity in MLL gene–rearranged infant acute lymphoblastic leukemia

Ronald W. Stam, Monique L. den Boer, Jules P. P. Meijerink, Marli E. G. Ebus, Godefridus J. Peters, Paul Noordhuis, Gritta E. Janka-Schaub, Scott A. Armstrong, Stanley J. Korsmeyer, Rob Pieters

Blood (2003) 101 (4): 1270–1276.

https://doi.org/10.1182/blood-2002-05-1600

Published: 2003

Journal Articles

Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell–induced apoptosis

E. Marion Schneider, Ingrid Lorenz, Michaela Müller-Rosenberger, Gerald Steinbach, Martina Kron, Gritta E. Janka-Schaub

Blood (2002) 100 (8): 2891–2898.

https://doi.org/10.1182/blood-2001-12-0260

Published: 2002

Journal Articles

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

Christian M. Zwaan, Gertjan J. L. Kaspers, Rob Pieters, Karel Hählen, Gritta E. Janka-Schaub, Christina H. van Zantwijk, Dieuwke R. Huismans, Esther de Vries, Marianne G. Rots, Godefridus J. Peters, Gerrit Jansen, Ursula Creutzig, Anjo J. P. Veerman

Blood (2002) 99 (1): 245–251.

https://doi.org/10.1182/blood.V99.1.245

Published: 2002

Journal Articles

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia

Christian M. Zwaan, Gert-Jan L. Kaspers, Rob Pieters, Nicole L. Ramakers-Van Woerden, Monique L. den Boer, Renate Wünsche, Maria M. A. Rottier, Karel Hählen, Elizabeth R. van Wering, Gritta E. Janka-Schaub, Ursula Creutzig, Anjo J. P. Veerman

Blood (2000) 96 (8): 2879–2886.

https://doi.org/10.1182/blood.V96.8.2879

Published: 2000

Journal Articles

TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

Nicole L. Ramakers-van Woerden, Rob Pieters, Annemarie H. Loonen, Isabelle Hubeek, Ellen van Drunen, H. Berna Beverloo, Rosalyn M. Slater, Jochen Harbott, Jeanette Seyfarth, Elisabeth R. van Wering, Karel Hählen, Kjeld Schmiegelow, Gritta E. Janka-Schaub, Anjo J. P. Veerman

Blood (2000) 96 (3): 1094–1099.

https://doi.org/10.1182/blood.V96.3.1094

Published: 2000

NARROW

High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95

Outcome of treatment in children with hypodiploid acute lymphoblastic leukemia

Up-regulation of c-FLIP S+R upon CD40 stimulation is associated with inhibition of CD95-induced apoptosis in primary precursor B-ALL

Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols

The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

Assessment of the Aryl Hydrocarbon Receptor Gene as a Therapeutic Target in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia

Asparagine synthetase expression is linked with l-asparaginase resistance in TEL-AML1–negative but not TEL-AML1–positive pediatric acute lymphoblastic leukemia

Sensitivity and Cross-Resistance to Deoxynucleoside Analogs in Childhood Acute Leukemia.

Germ-Line Genetic Variations in TP53 and Risk for Pediatric Acute Lymphoblastic Leukemia.

Genetic Variants of Ataxia Telangiectasia Mutated ( ATM ) and Susceptibility for Childhood T-Lineage Acute Lymphoblastic Leukemia.

Expression of P73 Splice Variants Correlates to Resistance to DNA Damaging Drugs in Childhood T-Lineage Acute Lymphoblastic Leukemia.

Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia

Thioguanine offers no advantage over mercaptopurine in maintenance treatment of childhood ALL: results of the randomized trial COALL-92

Sensitivity to l-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+pediatric ALL

Differential mRNA expression of Ara-C–metabolizing enzymes explains Ara-C sensitivity in MLL gene–rearranged infant acute lymphoblastic leukemia

Hemophagocytic lymphohistiocytosis is associated with deficiencies of cellular cytolysis but normal expression of transcripts relevant to killer-cell–induced apoptosis

Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome

Cellular drug resistance profiles in childhood acute myeloid leukemia: differences between FAB types and comparison with acute lymphoblastic leukemia

TEL/AML1 gene fusion is related to in vitro drug sensitivity forl-asparaginase in childhood acute lymphoblastic leukemia

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American Society of Hematology

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American Society of Hematology

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