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Gregor Hoermann
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Journal Articles

NT-Probnp As Personalized Medicine Tool and New Biomarker Predicting Response to Chemotherapy and Survival in AML

Irene Graf, Georg Greiner, Rodrig Marculescu, Karoline V. Gleixner, Susanne Herndlhofer, Gabriele Stefanzl, Paul Knoebl, Ulrich Jaeger, Alexander Hauswirth, Ilse Schwarzinger, Renate Thalhammer, Michael Kundi, Gregor Hoermann, Gerlinde Mitterbauer-Hohendanner, Peter Valent, Wolfgang R. Sperr
Journal: Blood
Blood (2021) 138 (Supplement 1): 3435.
DOI: https://doi.org/10.1182/blood-2021-149526
Published: 2021
Journal Articles

Deciphering the Mechanisms of Osteoblast-Induced Resistance of Leukemic Stem Cell (LSC) in Ph+ CML: Role of PI3-Kinase, BRD4 and MYC and Development of Strategies to Overcome Osteoblast-Induced Resistance

Yueksel Filik, Karin Bauer, Barbara Peter, Emir Hadzijusufovic, Georg Greiner, Nadine Witzeneder, Gregor Hoermann, Karoline V. Gleixner, Wolfgang R. Sperr, Peter Valent
Journal: Blood
Blood (2021) 138 (Supplement 1): 1481.
DOI: https://doi.org/10.1182/blood-2021-152415
Published: 2021
Journal Articles

Incidential Findings of Mutations in the PIGA Gene Are Highly Specific for the Presence of PNH Clones

Gregor Hoermann, Niroshan Nadarajah, Constance Baer, Frank Dicker, Kristina Loy, Sabit Delic, Frauke Bellos, Claudia Haferlach, Manja Meggendorfer, Torsten Haferlach, Wolfgang Kern
Journal: Blood
Blood (2021) 138 (Supplement 1): 1117.
DOI: https://doi.org/10.1182/blood-2021-153119
Published: 2021
Journal Articles

Whole Genome Sequencing Identifies Non- KIT Mutations and Cytogenetic Aberrations in Systemic Mastocytosis but Has Limited Sensitivity for Detection of KIT D816V

Gregor Hoermann, Manja Meggendorfer, Constance Baer, Heiko Müller, Wencke Walter, Stephan Hutter, Christian Pohlkamp, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Journal: Blood
Blood (2021) 138 (Supplement 1): 1495.
DOI: https://doi.org/10.1182/blood-2021-152956
Published: 2021
Journal Articles

Hereditary α tryptasemia is a valid genetic biomarker for severe mediator-related symptoms in mastocytosis

Clinical Trials & Observations
Georg Greiner, Bettina Sprinzl, Aleksandra Górska, Franz Ratzinger, Michael Gurbisz, Nadine Witzeneder, Klaus G. Schmetterer, Bettina Gisslinger, Goekhan Uyanik, Emir Hadzijusufovic, Harald Esterbauer, Karoline V. Gleixner, Maria T. Krauth, Michael Pfeilstöcker, Felix Keil, Heinz Gisslinger, Boguslaw Nedoszytko, Marek Niedoszytko, Wolfgang R. Sperr, Peter Valent, Gregor Hoermann
Journal: Blood
Blood (2021) 137 (2): 238–247.
DOI: https://doi.org/10.1182/blood.2020006157
Published: 2021
Includes: Supplemental data
Journal Articles

Phenotyping of Disease-Initiating CD34 + /CD38 ─ Stem Cells in BCR-ABL1 ─ MPN Reveals Expression of Multiple Cytokine Receptors and Resistance-Related Antigens

Daniel Ivanov, MSc, Jelena D. Milosevic Feenstra, PhD, Gregor Eisenwort, MD PhD, Robert Spörk, MSc, Alexandra Keller, PhD, Barbara Peter, Michael Willmann, Georg Greiner, Gabriele Stefanzl, Katharina Slavnitsch, Gregor Hoermann, Sybille Hofer, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Elisabeth Koller, Michael Fillitz, MD, Michael Pfeilstocker, MD, Thomas Rülicke, Thamer Sliwa, MD, Felix Keil, MD, Robert Kralovics, PhD, Peter Valent, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53.
DOI: https://doi.org/10.1182/blood-2020-140477
Published: 2020
Journal Articles

CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia

Johannes Schmoellerl, Inês Amorim Monteiro Barbosa, Thomas Eder, Tania Brandstoetter, Luisa Schmidt, Barbara Maurer, Selina Troester, Ha Thi Thanh Pham, Mohanty Sagarajit, Jessica Ebner, Gabriele Manhart, Ezgi Aslan, Stefan Terlecki-Zaniewicz, Christa Van der Veen, Gregor Hoermann, Nicolas Duployez, Arnaud Petit, Helene Lapillonne, Alexandre Puissant, Raphael Itzykson, Richard Moriggl, Michael Heuser, Roland Meisel, Peter Valent, Veronika Sexl, Johannes Zuber, Florian Grebien
Journal: Blood
Blood (2020) 136 (4): 387–400.
DOI: https://doi.org/10.1182/blood.2019003267
Published: 2020
Includes: Supplemental data
Journal Articles

Phenotypic Characterization of Leukemia-Initiating Stem Cells in Chronic Myelomonocytic Leukemia (CMML)

Gregor Eisenwort, MD PhD, Alexandra Keller, Michael Willmann, Irina Sadovnik, Greiner Georg, MD PhD, Karoline V. Gleixner, MD, Daniel Ivanov, MSc, Daniela Berger, Gabriele Stefanzl, Christiana Winding, DVM, Gregor Hoermann, Wolfgang R. Sperr, MD, Heinz Sill, MD, Peter Bettelheim, MD, Klaus Geissler, MD, Michael W. Deininger, Thomas Rülicke, Peter Valent, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4223.
DOI: https://doi.org/10.1182/blood-2019-122530
Published: 2019
Journal Articles

Consensus criteria for diagnosis, staging, and treatment response assessment of T-cell prolymphocytic leukemia

Philipp B. Staber, Marco Herling, Mar Bellido, Eric D. Jacobsen, Matthew S. Davids, Tapan Mahendra Kadia, Andrei Shustov, Olivier Tournilhac, Emmanuel Bachy, Francesco Zaja, Kimmo Porkka, Gregor Hoermann, Ingrid Simonitsch-Klupp, Claudia Haferlach, Stefan Kubicek, Marius E. Mayerhoefer, Georg Hopfinger, Ulrich Jaeger, Claire Dearden
Journal: Blood
Blood (2019) 134 (14): 1132–1143.
DOI: https://doi.org/10.1182/blood.2019000402
Published: 2019
Journal Articles

BRD4 Degradation Is a Potent Approach to Block MYC Expression and to Overcome Multiple Forms of Stem Cell Resistance in Ph + CML

Barbara Peter, Gregor Eisenwort, Alexandra Keller, Karin Bauer, Daniela Berger, Irina Sadovnik, Gabriele Stefanzl, Gregor Hoermann, Dominik Wolf, Zdenek Racil, Jiří Mayer, Johannes Zuber, Wolfgang R. Sperr, Georg E. Winter, Michael Willmann, Thomas Rülicke, Peter Valent
Journal: Blood
Blood (2018) 132 (Supplement 1): 1722.
DOI: https://doi.org/10.1182/blood-2018-99-111126
Published: 2018
Journal Articles

The CDK4/6 Inhibitor Palbociclib Exerts Growth-Inhibitory Effects on Neoplastic Mast Cells and Synergizes with Midostaurin in Producing Growth Arrest

Mathias A. Schneeweiss, Gabriele Stefanzl, Daniela Berger, Gregor Eisenwort, Mohamad Jawhar, Greiner Georg, MD PhD, Gregor Hoermann, Wolfgang R. Sperr, Michel Arock, Andreas Reiter, MD, Peter Valent, Karoline V. Gleixner, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1363.
DOI: https://doi.org/10.1182/blood-2018-99-116525
Published: 2018
Journal Articles

Molecular Quantification of Tissue Mast Cell Burden in Systemic Mastocytosis: A New Approach for Diagnostics and Prognostication

Greiner Georg, MD PhD, Michael Gurbisz, MSc, Franz Ratzinger, MD, Nadine Witzeneder, MSc, Svenja-Verena Class, Ingrid Simonitsch-Klupp, MD, Harald Esterbauer, MD PhD, Matthias Mayerhofer, MD, Wolfgang R. Sperr, Leonhard Muellauer, MD PhD, Peter Valent, Gregor Hoermann
Journal: Blood
Blood (2018) 132 (Supplement 1): 3043.
DOI: https://doi.org/10.1182/blood-2018-99-116492
Published: 2018
Journal Articles

CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis

Niklas Mueller, Daniel Wicklein, Gregor Eisenwort, Mohamad Jawhar, Daniela Berger, Gabriele Stefanzl, Georg Greiner, Alexandra Boehm, Christoph Kornauth, Leonhard Muellauer, Susanne Sehner, Gregor Hoermann, Wolfgang R. Sperr, Philipp B. Staber, Ulrich Jaeger, Johannes Zuber, Michel Arock, Udo Schumacher, Andreas Reiter, Peter Valent
Journal: Blood
Blood (2018) 132 (18): 1936–1950.
DOI: https://doi.org/10.1182/blood-2018-02-833582
Published: 2018
Includes: Supplemental data
Journal Articles

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

Clinical Trials & Observations
Edit Porpaczy, Sabrina Tripolt, Andrea Hoelbl-Kovacic, Bettina Gisslinger, Zsuzsanna Bago-Horvath, Emilio Casanova-Hevia, Emmanuelle Clappier, Thomas Decker, Sabine Fajmann, Daniela A. Fux, Georg Greiner, Sinan Gueltekin, Gerwin Heller, Harald Herkner, Gregor Hoermann, Jean-Jacques Kiladjian, Thomas Kolbe, Christoph Kornauth, Maria-Theresa Krauth, Robert Kralovics, Leonhard Muellauer, Mathias Mueller, Michaela Prchal-Murphy, Eva Maria Putz, Emmanuel Raffoux, Ana-Iris Schiefer, Klaus Schmetterer, Christine Schneckenleithner, Ingrid Simonitsch-Klupp, Cathrin Skrabs, Wolfgang R. Sperr, Philipp Bernhard Staber, Birgit Strobl, Peter Valent, Ulrich Jaeger, Heinz Gisslinger, Veronika Sexl
Journal: Blood
Blood (2018) 132 (7): 694–706.
DOI: https://doi.org/10.1182/blood-2017-10-810739
Published: 2018
Includes: Supplemental data
Journal Articles

JAK2-Inhibitor Therapy Associated Lymphomas in Myelofibrosis: Distinct Clinico-Pathological Features Recapitulated in a Mouse Model

Sabrina Tripolt, PhD, Edit Anna Porpaczy, MD, Andrea Hoelbl-Kovacic, PhD, Bettina Gisslinger, Zsuzanna Bago-Horvath, PhD, Emilio Casanova, PhD, Thomas Decker, PhD, Daniela Fux, PhD, Gerwin Heller, MD, Harald Herkner, MD, Thomas Kolbe, PhD, Christoph Kornauth, MD, Mathias Mueller, PhD, Michaela Prchal-Murphy, PhD, Ana Iris Schiefer, MD, Christine Schneckenleithner, PhD, Cathrin Skrabs, MD, Wolfgang R. Sperr, MD, Philipp Bernhard Staber, MD PhD, Birgit Strobl, PhD, Peter Valent, MD, Ingrid Simonitsch-Klupp, MD, Gregor Hoermann, MD, Jean-Jacques Kiladjian, MD PhD, Robert Kralovics, PhD, Maria-Theresa Krauth, MD, Ulrich Jaeger, MD, Veronika Sexl, MD PhD, Heinz Gisslinger
Journal: Blood
Blood (2017) 130 (Supplement 1): 1643.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1643.1643
Published: 2017
Journal Articles

Cardiovascular Scoring and Age-Related Mutations Predict the Occurrence of Adverse Vascular Events in CML Patients during Nilotinib Therapy

Emir Hadzijusufovic, DVM, Gregor Hoermann, MD, Susanne Herndlhofer, Wolfgang R. Sperr, MD, Bernd Jilma, MD, Gerit H. Schernthaner, MD, Peter Valent, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1619.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1619.1619
Published: 2017
Journal Articles

Digital Droplet PCR: Next Generation KIT D816V Testing As Advanced Tool for Diagnosis and Prognostication in Mastocytosis

Greiner Georg, MD PhD, Michael Gurbisz, MSc, Franz Ratzinger, MD, Nadine Witzeneder, MSc, Ingrid Simonitsch-Klupp, MD, Gerlinde Mitterbauer-Hohendanner, MD, Matthias Mayerhofer, MD, Leonhard Muellauer, MD PhD, Wolfgang R. Sperr, MD, Peter Valent, MD, Gregor Hoermann, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2927.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2927.2927
Published: 2017
Journal Articles

Integrated ATAC-Seq and Chemosensitivity Profiling Identifies Rational Drug Combinations in Ibrutinib-Treated CLL Patients

Gregory Ian Vladimer, PhD, Christian Schmidl, PhD, Andre Renderio, MS, Susanne Schnabl, MS, Tea Pemovska, PhD, Berend Snijder, PhD, Thomas Krausgruber, PhD, Nikolaus Krall, PhD, Mohammad Araghi, Rainer Hubmann, Anna Ringler, Dita Demirtas, Oscar Lopez de la Fuente, BSc, Martin Hilgrath, Cathrin Skrabs, MD, Edit Anna Porpaczy, MD, Michaela Gruber, MD PhD, Gregor Hoermann, MD, Stefan Kubicek, PhD, Philipp Bernhard Staber, MD PhD, Medhat M. Shehata, MD, Giulio Superti-Furga, PhD, Christoph Bock, PhD, Ulrich Jaeger, MD
Journal: Blood
Blood (2017) 130 (Suppl_1): 800.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.800.800
Published: 2017
Journal Articles

Next-Generation Functional Drug Screening for Patients with Aggressive Hematologic Malignancies

Philipp Bernhard Staber, MD PhD, Berend Snijder, PhD, Gregory Ian Vladimer, PhD, Nikolaus Krall, PhD, Katsuhiro Miura, MD, Ann-Sofie Schmolke, Christoph Kornauth, MD, Oscar Lopez de la Fuente, BSc, Hye-Soo Choi, Emiel van der Kouwe, Lukas Kazianka, MD, Johannes Bigenzahn1, MD PhD, Gregor Hoermann, MD, Nicole Prutsch, Olaf Merkel, PhD, Anna Ringler, Georg Jeryczynski, MD, Marius Mayerhoefer, MD, Ingrid Simonitsch-Klupp, MD, Franz X Felberbauer, MD, Leonhard Muellauer, MD PhD, Gerald W Prager, MD, Belgin Korkmaz, MD, Lukas Kenner, MD, Wolfgang R. Sperr, MD, Robert Kralovics, PhD, Heinz Gisslinger, Peter Valent, MD, Stefan Kubicek, PhD, Ulrich Jaeger, MD, Giulio Superti-Furga, PhD
Journal: Blood
Blood (2017) 130 (Suppl_1): 855.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.855.855
Published: 2017
Journal Articles

First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia

Clinical Trials & Observations Brief Report
Bernd Boidol, Christoph Kornauth, Emiel van der Kouwe, Nicole Prutsch, Lukas Kazianka, Sinan Gültekin, Gregor Hoermann, Marius E. Mayerhoefer, Georg Hopfinger, Alexander Hauswirth, Michael Panny, Marie-Bernadette Aretin, Bernadette Hilgarth, Wolfgang R. Sperr, Peter Valent, Ingrid Simonitsch-Klupp, Richard Moriggl, Olaf Merkel, Lukas Kenner, Ulrich Jäger, Stefan Kubicek, Philipp B. Staber
Journal: Blood
Blood (2017) 130 (23): 2499–2503.
DOI: https://doi.org/10.1182/blood-2017-05-785683
Published: 2017
Includes: Supplemental data