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Giovanni Palladini
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Journal Articles

How I treat AL amyloidosis

Giovanni Palladini, Giampaolo Merlini
Journal: Blood
Blood (2022) 139 (19): 2918–2930.
DOI: https://doi.org/10.1182/blood.2020008737
Published: 2022
Journal Articles

Two-hit strategy for treating AL amyloidosis?

Clinical Trials & Observations
Giampaolo Merlini, Giovanni Palladini
Journal: Blood
Blood (2021) 138 (25): 2596–2598.
DOI: https://doi.org/10.1182/blood.2021013817
Published: 2021
Journal Articles

Systemic Light Chain Amyloidosis across Europe: Key Outcomes from a Retrospective Study of 4500 Patients

Giovanni Palladini, Stefan Schönland, Giampaolo Merlini, Paolo Milani, Arnaud Jaccard, Frank Bridoux, Meletios A. Dimopoulos, Sriram Ravichandran, Ute Hegenbart, Wilfried Roeloffzen, M. Teresa Cibeira, Hermine Agis, Monique C. Minnema, Rui Bergantim, Roman Hajek, Cristina João, Alexandros Leonidakis, Giorgos Cheliotis, Pieter Sonneveld, Efstathios Kastritis, Ashutosh D. Wechalekar
Journal: Blood
Blood (2021) 138 (Supplement 1): 153.
DOI: https://doi.org/10.1182/blood-2021-152675
Published: 2021
Journal Articles

Graded Cardiac Response Criteria for AL Amyloidosis: The Impact of Depth of Cardiac Response on Survival

Eli Muchtar, Angela Dispenzieri, Brendan Wisniowski, Giovanni Palladini, Paolo Milani, Giampaolo Merlini, Stefan Schönland, Kaya Veelken, Ute Hegenbart, Shaji Kumar, Efstathios Kastritis, Meletios A. Dimopoulos, Michaela Liedtke, Ronald Witteles, Vaishali Sanchorawala, Raphael Szalat, Heather J Landau, Erica Petrlik, Suzanne Lentzsch, Alexander Coltoff, Joan Bladé, M. Teresa Cibeira, Oliver Cohen, Darren Foard, Ashutosh D. Wechalekar, Morie A. Gertz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2720.
DOI: https://doi.org/10.1182/blood-2021-149222
Published: 2021
Journal Articles

Graded Renal Response Criteria for Light Chain (AL) Amyloidosis

Eli Muchtar, Brendan Wisniowski, Giovanni Palladini, Paolo Milani, Giampaolo Merlini, Stefan Schönland, Kaya Veelken, Ute Hegenbart, Angela Dispenzieri, Shaji Kumar, Nelson Leung, Efstathios Kastritis, Meletios A. Dimopoulos, Michaela Liedtke, Ronald Witteles, Vaishali Sanchorawala, Raphael Szalat, Heather J Landau, Erica Petrlik, Suzanne Lentzsch, Alexander Coltoff, Joan Bladé, M. Teresa Cibeira, Oliver C Cohen, Darren Foard, Julian D Gillmore, Helen J Lachmann, Ashutosh D. Wechalekar, Morie A. Gertz
Journal: Blood
Blood (2021) 138 (Supplement 1): 2721.
DOI: https://doi.org/10.1182/blood-2021-149594
Published: 2021
Journal Articles

Efficacy and Safety of Daratumumab Monotherapy in Newly Diagnosed Patients with Stage 3B Light Chain Amyloidosis: A Phase 2 Study By the European Myeloma Network

Efstathios Kastritis, Monique C. Minnema, Meletios A. Dimopoulos, Giampaolo Merlini, Foteini Theodorakakou, Despina Fotiou, Antoine Huart, Karim Belhadj, Alexandros Leonidakis, Kyriaki Manousou, Pieter Sonneveld, Giovanni Palladini
Journal: Blood
Blood (2021) 138 (Supplement 1): 2730.
DOI: https://doi.org/10.1182/blood-2021-152540
Published: 2021
Journal Articles

Single Molecule Real-Time Sequencing of the M Protein (SMaRT M-Seq): Toward Personalized Medicine Approaches in Monoclonal Gammopathies

Pasquale Cascino, Alice Nevone, Claudia Scopelliti, Maria Girelli, Giulia Mazzini, Serena Caminito, Giancarlo Russo, Paolo Milani, Marco Basset, Andrea Foli, Francesca Fazio, Simona Casarini, Margherita Massa, Margherita Bozzola, Jessica Ripepi, Melania Antonietta Sesta, Gloria Acquafredda, Marica De Cicco, Antonia Moretta, Paola Rognoni, Enrico Milan, Stefano Ricagno, Francesca Lavatelli, Maria Teresa Petrucci, Catherine Klersy, Giampaolo Merlini, Giovanni Palladini, Mario Nuvolone
Journal: Blood
Blood (2021) 138 (Supplement 1): 2673.
DOI: https://doi.org/10.1182/blood-2021-147227
Published: 2021
Journal Articles

Definition and Clinical Significance of the MGUS-like Phenotype: A Study in 5,114 Patients (Pts) with Monoclonal Gammopathies

Leire Burgos, Luis Esteban Tamariz-Amador, Noemí Puig, María Teresa Cedena, Tomas Jelinek, Sarah K Johnson, Paolo Milani, Lourdes Cordon, José J Pérez, Marta Lasa, Rosalinda Termini, Albert Oriol, Miguel-Teodoro Hernández, Luis Palomera, Rafael Martinez Martinez, Javier de la Rubia, Felipe De Arriba, Rafael Rios, Maria Esther González, Mercedes Gironella, Valentin Cabañas, Maria Casanova, Isabel Krsnik, Albert Pérez, Veronica Gonzalez De La Calle, Paula Rodríguez-Otero, Vladimir Maisnar, Roman Hajek, Frits van Rhee, Victor H Jimenez-Zepeda, Giovanni Palladini, Paolo Milani, Alberto Orfao, Laura Rosinol, Joan Bladé Creixenti, Joaquín Martínez-López, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San-Miguel, Bruno Paiva
Journal: Blood
Blood (2021) 138 (Supplement 1): 541.
DOI: https://doi.org/10.1182/blood-2021-150092
Published: 2021
Journal Articles

Subcutaneous Daratumumab with Bortezomib, Cyclophosphamide, and Dexamethasone in Patients with Newly Diagnosed Light Chain (AL) Amyloidosis: 18-Month Analysis of the Phase 3 ANDROMEDA Study

Raymond Comenzo, Giovanni Palladini, Efstathios Kastritis, Monique C. Minnema, Ashutosh D. Wechalekar, Arnaud Jaccard, Angela Dispenzieri, Hans C. Lee, Vaishali Sanchorawala, Simon D. Gibbs, Peter Mollee, Chris P. Venner, Jin Lu, Stefan Schönland, Moshe Gatt, Kenshi Suzuki, Kihyun Kim, M. Teresa Cibeira, Meral Beksac, Edward Libby, Jason Valent, Vania Hungria, Sandy W. Wong, Michael Rosenzweig, Naresh Bumma, NamPhuong Tran, Xiang Qin, Samer Khaled, Jessica Vermeulen, Giampaolo Merlini
Journal: Blood
Blood (2021) 138 (Supplement 1): 159.
DOI: https://doi.org/10.1182/blood-2021-146820
Published: 2021
Journal Articles

Management of AL amyloidosis in 2020

Giovanni Palladini, Paolo Milani, Giampaolo Merlini
Journal: Blood
Blood (2020) 136 (23): 2620–2627.
DOI: https://doi.org/10.1182/blood.2020006913
Published: 2020
Journal Articles

The Italian Medicines Agency Prospective Registry of Bortezomib-Based Treatment in AL Amyloidosis

Giovanni Palladini, MD PhD, Paolo Milani, MDPhD, Simone Celant, Valentina Summa, MD, Giovanni Affronti, Pier Paolo Olimpieri, PhD, Sandra Petraglia, MD, Andrea Foli, MD, Mario Nuvolone, MD PhD, Giampaolo Merlini, MD, Pierluigi Russo, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 22.
DOI: https://doi.org/10.1182/blood-2020-141563
Published: 2020
Journal Articles

Reduction in Absolute Involved Free Light Chain and Difference between Involved and Uninvolved Free Light Chain Is Associated with Prolonged Major Organ Deterioration Progression-Free Survival in Patients with Newly Diagnosed AL Amyloidosis Receiving Bortezomib, Cyclophosphamide, and Dexamethasone with or without Daratumumab: Results from Andromeda

Raymond L. Comenzo, MD, Efstathios Kastritis, MD, Giovanni Palladini, MD PhD, Monique C. Minnema, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM, Arnaud Jaccard, MD PhD, Vaishali Sanchorawala, MD, Hans C. Lee, MD, Simon D. Gibbs, FRACP, FRCPA, MBBS, Peter Mollee, FRACP,MBBS,MSc,FRCPA, Christopher P. Venner, MD, Jin Lu, Stefan Schönland, MD, Moshe Gatt, MD, Kenshi Suzuki, MD PhD, Kihyun Kim, MD PhD, M. Teresa Cibeira, MD PhD, Meral Beksac, MD, Edward Libby, MD, Jason Valent, MD, Vania T. M. Hungria, MD PhD, Sandy W. Wong, MD, Michael Rosenzweig, MD, Naresh Bumma, MD, Dominique Chauveau, MD PhD, Meletios A Dimopoulos, NamPhuong Tran, MD, Xiang Qin, MD PhD, Sandra Y. Vasey, MSc, Brenda Tromp, MSc, Brendan M. Weiss, MD, Jessica Vermeulen, MD PhD, Giampaolo Merlini, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 48–50.
DOI: https://doi.org/10.1182/blood-2020-137582
Published: 2020
Journal Articles

First Glimpse on Real-World Efficacy Outcomes for 2000 Patients with Systemic Light Chain Amyloidosis in Europe: A Retrospective Observational Multicenter Study By the European Myeloma Network

Giovanni Palladini, MD PhD, Stefan Schönland, MD, Giampaolo Merlini, MD, Paolo Milani, MDPhD, Arnaud Jaccard, MD PhD, Frank Bridoux, MD PhD, Wilfried Roeloffzen, MD PhD, M. Teresa Cibeira, MD PhD, Hermine Agis, MD, Monique C. Minnema, MD PhD, Rui Bergantim, MD, Roman Hajek, MD PhD, Cristina João, MD PhD MSc, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM, Pieter Sonneveld, MD PhD, Efstathios Kastritis, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 50–51.
DOI: https://doi.org/10.1182/blood-2020-140708
Published: 2020
Journal Articles

Light Chain Deposition Disease: First Analysis of an International Study in 359 Patients

Paolo Milani, MDPhD, Nelson Leung, MD, Efstathios Kastritis, MD, Stefan Schönland, MD, Ute Hegenbart, MD, Frank Bridoux, MD, Florent Joly, MD, Sascha A Tuchman, MD, Victor Jimenez-Zepeda, MD, Sriram Ravichandran, MBBS, MRCP, FRCPath, Holly Lee, MD, Tamara Berno, MD, Giampaolo Merlini, MD, Giovanni Palladini, MD PhD, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
DOI: https://doi.org/10.1182/blood-2020-141662
Published: 2020
Journal Articles

Health-Related Quality of Life in Patients with AL Amyloidosis Treated with Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone: Results from the Phase 3 Andromeda Study

Vaishali Sanchorawala, MD, Giovanni Palladini, MD PhD, Monique C. Minnema, Arnaud Jaccard, MD PhD, Hans C. Lee, MD, Simon D. Gibbs, FRACP, FRCPA, MBBS, Peter Mollee, FRACP,MBBS,MSc,FRCPA, Christopher P. Venner, MD, Jin Lu, Stefan Schönland, MD, Moshe Gatt, MD, Kenshi Suzuki, MD PhD, Kihyun Kim, MD, M. Teresa Cibeira, MD PhD, Meral Beksac, MD, Edward Libby, MD, Jason Valent, MD, Vania T. M. Hungria, MD PhD, Sandy W. Wong, MD, Michael Rosenzweig, MD, Naresh Bumma, MD, Dominique Chauveau, MD PhD, Katharine S. Gries, PhD PharmD, John Fastenau, RPh, MPH, PhD, NamPhuong Tran, MD, Xiang Qin, MD PhD, Sandra Y. Vasey, MSc, Brenda Tromp, MSc, Brendan M. Weiss, MD, Jessica Vermeulen, MD PhD, Giampaolo Merlini, MD, Raymond L. Comenzo, MD, Efstathios Kastritis, MD, Ashutosh D. Wechalekar, MBBS,FRCP,FRCPath,DM
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–40.
DOI: https://doi.org/10.1182/blood-2020-139438
Published: 2020
Journal Articles

Rapid and Deep Hematologic Responses Are Associated with Improved Major Organ Deterioration Progression-Free Survival in Newly Diagnosed AL Amyloidosis: Results from Andromeda

Ashutosh D. Wechalekar, MD, Giovanni Palladini, MD PhD, Giampaolo Merlini, MD, Raymond L. Comenzo, MD, Arnaud Jaccard, MD PhD, NamPhuong Tran, MD, Huiling Pei, PhD, Sandra Y. Vasey, MSc, Brenda Tromp, MSc, Brendan M. Weiss, MD, Jessica Vermeulen, MD PhD, Efstathios Kastritis, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 6–7.
DOI: https://doi.org/10.1182/blood-2020-140514
Published: 2020
Journal Articles

Sars-Cov-2 Infection and Systemic Light Chain Amyloidosis: The International Society of Amyloidosis' Survey

Paolo Milani, MDPhD, Vaishali Sanchorawala, MD, Ramon Lecumberri, MD PhD, Sunil Saith, MD, Mathew S. Maurer, MD, M. Teresa Cibeira, MD PhD, Giampaolo Merlini, MD, Stefan Schönland, MD, Giovanni Palladini, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11.
DOI: https://doi.org/10.1182/blood-2020-141569
Published: 2020
Journal Articles

Daratumumab plus CyBorD for patients with newly diagnosed AL amyloidosis: safety run-in results of ANDROMEDA

Clinical Trials & Observations
Giovanni Palladini, Efstathios Kastritis, Mathew S. Maurer, Jeffrey Zonder, Monique C. Minnema, Ashutosh D. Wechalekar, Arnaud Jaccard, Hans C. Lee, Naresh Bumma, Jonathan L. Kaufman, Eva Medvedova, Tibor Kovacsovics, Michael Rosenzweig, Vaishali Sanchorawala, Xiang Qin, Sandra Y. Vasey, Brendan M. Weiss, Jessica Vermeulen, Giampaolo Merlini, Raymond L. Comenzo
Journal: Blood
Blood (2020) 136 (1): 71–80.
DOI: https://doi.org/10.1182/blood.2019004460
Published: 2020
Includes: Supplemental data
Journal Articles

A prospective phase 2 trial of daratumumab in patients with previously treated systemic light-chain amyloidosis

Clinical Trials & Observations
Murielle Roussel, Giampaolo Merlini, Sylvie Chevret, Bertrand Arnulf, Anne Marie Stoppa, Aurore Perrot, Giovanni Palladini, Lionel Karlin, Bruno Royer, Antoine Huart, Margaret Macro, Pierre Morel, Laurent Frenzel, Cyrille Touzeau, Eileen Boyle, Véronique Dorvaux, Fabien Le Bras, David Lavergne, Frank Bridoux, Arnaud Jaccard
Journal: Blood
Blood (2020) 135 (18): 1531–1540.
DOI: https://doi.org/10.1182/blood.2019004369
Published: 2020
Includes: Supplemental data
Journal Articles

Nonlymphoplasmacytic lymphomas associated with light-chain amyloidosis

Clinical Trials & Observations
Marco Basset, Irene Defrancesco, Paolo Milani, Mario Nuvolone, Sara Rattotti, Andrea Foli, Silvia Mangiacavalli, Marzia Varettoni, Pietro Benvenuti, Claudio Salvatore Cartia, Marco Paulli, Giampaolo Merlini, Luca Arcaini, Giovanni Palladini
Journal: Blood
Blood (2020) 135 (4): 293–296.
DOI: https://doi.org/10.1182/blood.2019002762
Published: 2020