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Journal Articles

Unique and Unexpected Functional Activities of Hematopoietically Active Cytokines Truncated By Dipeptidylpeptidase-4 (DPP4)

Heather A. O'Leary, PhD, Charlie Mantel, Man Ryul Lee, PhD, Xianyin Lai, PhD, Scott Cooper, BS, Giao Hangoc, DVM, PhD, H. Scott Boswell, MD, Hal E. Broxmeyer, PhD

Blood (2014) 124 (21): 2922.

https://doi.org/10.1182/blood.V124.21.2922.2922

Published: 2014

Journal Articles

Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation

Charlie Mantel, Heather A. O'Leary, PhD, Brahmananda Reddy Chitteti, PhD, Xinxin Huang, PhD, Scott Cooper, BS, Giao Hangoc, DVM, PhD, Nickolay Brustovetsky, PhD, Edward F. Srour, PhD, Man Ryul Lee, PhD, Steven Messina-Graham, Nadia Falah, MD, Reuben Kapur, PhD, Louis M. Pelus, PhD, Mircea Ivan, MD, PhD, Kye-Seong Kim, PhD, Hal E. Broxmeyer, PhD

Blood (2014) 124 (21): 2905.

https://doi.org/10.1182/blood.V124.21.2905.2905

Published: 2014

Journal Articles

Mild Hyperthermia Treatment Of CD34+ Human Cord Blood Cells Increases Lipid Raft Aggregation Resulting In An Earlier Engraftment In NSG Mice Following Transplantation

Maegan L. Capitano, Ph.D., Giao Hangoc, DVM, Ph.D., Hal E. Broxmeyer, PhD

Blood (2013) 122 (21): 3241.

https://doi.org/10.1182/blood.V122.21.3241.3241

Published: 2013

Journal Articles

DPP4 (CD26) Truncation Of GM-CSF and IL-3 Alters Their Signaling and Functional Activity In Normal and Leukemic Hematopoietic Stem and Progenitor Cells

Heather A. O'Leary, Ph.D., Charlie Mantel, Xianyin Lai, Ph.D., Scott Cooper, BS, Giao Hangoc, DVM, Ph.D., H. Scott Boswell, M.D., Frank Witzmann, Ph.D., Hal E. Broxmeyer, PhD

Blood (2013) 122 (21): 1206.

https://doi.org/10.1182/blood.V122.21.1206.1206

Published: 2013

Journal Articles

Mouse hematopoietic cell–targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype

Charlie Mantel, Steven Messina-Graham, Akira Moh, Scott Cooper, Giao Hangoc, Xin-Yuan Fu, Hal E. Broxmeyer

Blood (2012) 120 (13): 2589–2599.

https://doi.org/10.1182/blood-2012-01-404004

Published: 2012

Includes: Supplemental data

Journal Articles

CD1d expression on and regulation of murine hematopoietic stem and progenitor cells

Hal E. Broxmeyer, Kent Christopherson, Giao Hangoc, Scott Cooper, Charlie Mantel, Gourapura J. Renukaradhya, Randy R. Brutkiewicz

Blood (2012) 119 (24): 5731–5741.

https://doi.org/10.1182/blood-2012-01-404012

Published: 2012

Includes: Supplemental data

Journal Articles

DEK Regulates Hematopoietic Stem Engraftment and Progenitor Cell Proliferation

Hal E. Broxmeyer, PhD, Ferdinand Kappas, MD, Nirit Mor-Vaknin, PhD, MSc, Maureen Legendre, John Kinzfogl, Scott Cooper, BS, Giao Hangoc, DVM, David M. Markovitz, MD

Blood (2011) 118 (21): 1275.

https://doi.org/10.1182/blood.V118.21.1275.1275

Published: 2011

Journal Articles

Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells

John Kinzfogl, Giao Hangoc, Hal E. Broxmeyer

Blood (2011) 118 (3): 565–575.

https://doi.org/10.1182/blood-2010-12-325381

Published: 2011

Journal Articles

STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis

Mark H. Kaplan, Nicole L. Glosson, Gretta L. Stritesky, Norman Yeh, John Kinzfogl, Sara L. Rohrabaugh, Ritobrata Goswami, Duy Pham, David E. Levy, Randy R. Brutkiewicz, Janice S. Blum, Scott Cooper, Giao Hangoc, Hal E. Broxmeyer

Blood (2011) 117 (23): 6198–6201.

https://doi.org/10.1182/blood-2011-02-334367

Published: 2011

Journal Articles

TIP110/p110 nrb /SART3/p110 regulation of hematopoiesis through CMYC

Ying Liu, Khalid Timani, Charlie Mantel, Yan Fan, Giao Hangoc, Scott Cooper, Johnny J. He, Hal E. Broxmeyer

Blood (2011) 117 (21): 5643–5651.

https://doi.org/10.1182/blood-2010-12-325332

Published: 2011

Includes: Supplemental data

Journal Articles

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood

Hal E. Broxmeyer, Man-Ryul Lee, Giao Hangoc, Scott Cooper, Nutan Prasain, Young-June Kim, Coleen Mallett, Zhaohui Ye, Scott Witting, Kenneth Cornetta, Linzhao Cheng, Mervin C. Yoder

Blood (2011) 117 (18): 4773–4777.

https://doi.org/10.1182/blood-2011-01-330514

Published: 2011

Includes: Supplemental data

Journal Articles

The Neurexin I Alpha/Neurexophilin Axis as An Anti-Proliferative Factor In Human Cord Blood and Murine Bone Marrow Hematopoiesis.

John Kinzfogl, Giao Hangoc, DVM, PhD, Hal E. Broxmeyer, PhD

Blood (2010) 116 (21): 2627.

https://doi.org/10.1182/blood.V116.21.2627.2627

Published: 2010

Journal Articles

Mad2 Haploinsufficiency Unexpectedly Protects Hematopoietic Progenitor Cells From Ara-C Mediated Cytotoxicity.

Sara Rohrabaugh, BS, Giao Hangoc, DVM, PhD, Hal E. Broxmeyer, PhD

Blood (2009) 114 (22): 2543.

https://doi.org/10.1182/blood.V114.22.2543.2543

Published: 2009

Journal Articles

The Neurexin Iα/Neurexophilin1 Axis as a Myelosuppressive Factor in Human Cord Blood and Murine Bone Marrow Hematopoiesis.

John Michael Kinzfogl, MS, Giao Hangoc, DVM, PhD, Hal E. Broxmeyer, PhD

Blood (2009) 114 (22): 2545.

https://doi.org/10.1182/blood.V114.22.2545.2545

Published: 2009

Journal Articles

CD26/Dipeptidylpeptidase IV Regulates Potency of Selected Hematopoietic Growth Factors through Truncation, and Recovery In Vivo After Cytotoxic Stress.

Hal E. Broxmeyer, PhD, Jonathan Hoggatt, MS, Scott Cooper, Giao Hangoc, DVM, PhD, Louis M. Pelus, PhD, Timothy B. Campbell

Blood (2009) 114 (22): 3602.

https://doi.org/10.1182/blood.V114.22.3602.3602

Published: 2009

Journal Articles

Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation

Timothy B. Campbell, Sunanda Basu, Giao Hangoc, Wen Tao, Hal E. Broxmeyer

Blood (2009) 114 (16): 3392–3401.

https://doi.org/10.1182/blood-2008-12-195214

Published: 2009

Includes: Supplemental data

Journal Articles

Targeted disruption of Zfp36l2 , encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

Deborah J. Stumpo, Hal E. Broxmeyer, Toni Ward, Scott Cooper, Giao Hangoc, Yang Jo Chung, William C. Shelley, Eric K. Richfield, Manas K. Ray, Mervin C. Yoder, Peter D. Aplan, Perry J. Blackshear

Blood (2009) 114 (12): 2401–2410.

https://doi.org/10.1182/blood-2009-04-214619

Published: 2009

Includes: Supplemental data

Journal Articles

Targeted Disruption of Zfp36l2 , Encoding a CCCH Tandem Zinc Finger RNA-Binding Protein, Results in Defective Hematopoiesis.

Deborah J. Stumpo, PhD, Hal E. Broxmeyer, PhD, Scott Cooper, Giao Hangoc, DVM, PhD, Peter D. Aplan, MD, Yang Jo Chung, PhD, Mervin C. Yoder, MD, William C. Shelley, Perry J. Blackshear

Blood (2008) 112 (11): 1401.

https://doi.org/10.1182/blood.V112.11.1401.1401

Published: 2008

Journal Articles

Inhibition of CD26/Dipeptidylpeptidase IV Enhances Proliferation of Hematopoietic Progenitor Cells Induced by Selected Colony Stimulating Factors

Hal E. Broxmeyer, PhD, Scott Cooper, Giao Hangoc, DVM, Timothy B. Campbell

Blood (2008) 112 (11): 2456.

https://doi.org/10.1182/blood.V112.11.2456.2456

Published: 2008

Journal Articles

Selected Members of the Angiopoietin-Like Family of Human Proteins Enhance Survival and Replating Capacity of Immature Human Hematopoietic Progenitor Cells.

Hal E. Broxmeyer, PhD, Edward F. Srour, PhD, Scott Cooper, BS, Carrie T. Wallace, Giao Hangoc, DVM, Byung Youn, PhD

Blood (2007) 110 (11): 3367.

https://doi.org/10.1182/blood.V110.11.3367.3367

Published: 2007

NARROW

Unique and Unexpected Functional Activities of Hematopoietically Active Cytokines Truncated By Dipeptidylpeptidase-4 (DPP4)

Mitigation of a Newly Discovered Phenomenon, Extra Physiologic Oxygen Shock/Stress (EPHOSS), Mediated By the Mitochondria Permeability Transition Pore, Greatly Improves Stem Cell Collection and Transplantation

Mild Hyperthermia Treatment Of CD34+ Human Cord Blood Cells Increases Lipid Raft Aggregation Resulting In An Earlier Engraftment In NSG Mice Following Transplantation

DPP4 (CD26) Truncation Of GM-CSF and IL-3 Alters Their Signaling and Functional Activity In Normal and Leukemic Hematopoietic Stem and Progenitor Cells

Mouse hematopoietic cell–targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging–like phenotype

CD1d expression on and regulation of murine hematopoietic stem and progenitor cells

DEK Regulates Hematopoietic Stem Engraftment and Progenitor Cell Proliferation

Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells

STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis

TIP110/p110 nrb /SART3/p110 regulation of hematopoiesis through CMYC

Hematopoietic stem/progenitor cells, generation of induced pluripotent stem cells, and isolation of endothelial progenitors from 21- to 23.5-year cryopreserved cord blood

The Neurexin I Alpha/Neurexophilin Axis as An Anti-Proliferative Factor In Human Cord Blood and Murine Bone Marrow Hematopoiesis.

Mad2 Haploinsufficiency Unexpectedly Protects Hematopoietic Progenitor Cells From Ara-C Mediated Cytotoxicity.

The Neurexin Iα/Neurexophilin1 Axis as a Myelosuppressive Factor in Human Cord Blood and Murine Bone Marrow Hematopoiesis.

CD26/Dipeptidylpeptidase IV Regulates Potency of Selected Hematopoietic Growth Factors through Truncation, and Recovery In Vivo After Cytotoxic Stress.

Overexpression of Rheb2 enhances mouse hematopoietic progenitor cell growth while impairing stem cell repopulation

Targeted disruption of Zfp36l2 , encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis

Targeted Disruption of Zfp36l2 , Encoding a CCCH Tandem Zinc Finger RNA-Binding Protein, Results in Defective Hematopoiesis.

Inhibition of CD26/Dipeptidylpeptidase IV Enhances Proliferation of Hematopoietic Progenitor Cells Induced by Selected Colony Stimulating Factors

Selected Members of the Angiopoietin-Like Family of Human Proteins Enhance Survival and Replating Capacity of Immature Human Hematopoietic Progenitor Cells.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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