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Gary J. Schiller
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Journal Articles

Follow-up of patients with R/R FLT3- mutation-positive AML treated with gilteritinib in the phase 3 ADMIRAL trial

Clinical Trials & Observations
Alexander E. Perl, Richard A. Larson, Nikolai A. Podoltsev, Stephen A Strickland, Eunice S. Wang, Ehab Atallah, Gary J. Schiller, Giovanni Martinelli, Andreas Neubauer, Jorge Sierra, Pau Montesinos, Christian Récher, Sung-Soo Yoon, Naoko Hosono, Masahiro Onozawa, Shigeru Chiba, Hee-Je Kim, Nahla Hasabou, Qiaoyang Lu, Ramon Tiu, Mark J Levis
Journal: Blood
Blood blood.2021011583.
DOI: https://doi.org/10.1182/blood.2021011583
Published: 2022
Includes: Supplemental data
Journal Articles

Ivosidenib (IVO) in Combination with Azacitidine (AZA) in Newly Diagnosed (ND) Older Patients with IDH1 R132-Mutated Acute Myeloid Leukemia (AML) Induces High Response Rates: A Phase 2 Sub-Study of the Beat AML Master Trial

Prapti Patel, Amy S. Ruppert, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley Owen Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Alice S. Mims
Journal: Blood
Blood (2021) 138 (Supplement 1): 875.
DOI: https://doi.org/10.1182/blood-2021-149115
Published: 2021
Journal Articles

Entospletinib (ENTO) and Decitabine (DEC) Combination Therapy in Older Newly Diagnosed (ND) Acute Myeloid Leukemia (AML) Patients with Mutant TP53 or Complex Karyotype Is Associated with Poor Response and Survival: A Phase 2 Sub-Study of the Beat AML Master Trial

Vu H. Duong, Amy S. Ruppert, Alice S. Mims, Uma Borate, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William G. Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti A. Patel, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Ronan T. Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Michael M. Boyiadzis
Journal: Blood
Blood (2021) 138 (Supplement 1): 1279.
DOI: https://doi.org/10.1182/blood-2021-151234
Published: 2021
Journal Articles

Pelabresib (CPI-0610) Monotherapy in Patients with Myelofibrosis - Update of Clinical and Translational Data from the Ongoing Manifest Trial

Marina Kremyanskaya, John Mascarenhas, Francesca Palandri, Alessandro Vannucchi, Srdan Verstovsek, Claire N. Harrison, Prithviraj Bose, Gary J. Schiller, Raajit Rampal, Mark W. Drummond, Vikas Gupta, Andrea Patriarca, Nikki Granacher, Joseph Scandura, Witold Prejzner, Lino L. Teichmann, Natalia Curto-Garcia, Ronald Hoffman, Gozde Colak, Zheng Ren, Suresh Bobba, Jike Cui, Sergey Efuni, Moshe Talpaz
Journal: Blood
Blood (2021) 138 (Supplement 1): 141.
DOI: https://doi.org/10.1182/blood-2021-150172
Published: 2021
Journal Articles

Preliminary Results from the Flu/Cy/Alemtuzumab Arm of the Phase I BALLI-01 Trial of UCART22, an Anti-CD22 Allogeneic CAR-T Cell Product, in Adult Patients with Relapsed or Refractory (R/R) CD22+ B-Cell Acute Lymphoblastic Leukemia (B-ALL)

Nitin Jain, Gail J. Roboz, Marina Konopleva, Hongtao Liu, Gary J. Schiller, Elias J. Jabbour, Deborah Whitfield, Asifa Haider, Oleg Zernovak, Mark G. Frattini, Carrie Brownstein, Richard A. Larson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1746.
DOI: https://doi.org/10.1182/blood-2021-150779
Published: 2021
Journal Articles

Once Weekly Oral Selinexor, Pomalidomide, and Dexamethasone in Relapsed Refractory Multiple Myeloma

Darrell J White, Christine I. Chen, Muhamed Baljevic, Sascha A. Tuchman, Nizar J. Bahlis, Gary J. Schiller, Brea Lipe, Rami Kotb, Heather J. Sutherland, William I. Bensinger, Sumit Madan, Michael Sebag, Suzanne Lentzsch, Natalie S. Callander, Noa Biran, Christopher P. Venner, Richard Leblanc, Jorge Monge, Evgeni Chubar, Tamar Tadmor, Noa Lavi, Merav Leiba, Andrew DeCastro, Dane R. Van Domelen, Chris Zhang, Moran Mishal, Ohad S. Bentur, Jatin J. Shah, Sharon Shacham, Michael G. Kauffman, Cristina J. Gasparetto
Journal: Blood
Blood (2021) 138 (Supplement 1): 2748.
DOI: https://doi.org/10.1182/blood-2021-148759
Published: 2021
Journal Articles

Selinexor-Based Regimens in Patients with Multiple Myeloma after Prior Anti-B-Cell Maturation Antigen Treatment

Muhamed Baljevic, Cristina Gasparetto, Gary J. Schiller, Sascha A. Tuchman, Natalie S. Callander, Suzanne Lentzsch, Jorge Monge, Rami Kotb, Nizar J. Bahlis, Darrell White, Christine I. Chen, Heather J. Sutherland, Sumit Madan, Richard Leblanc, Michael Sebag, Christopher P. Venner, William I. Bensinger, Noa Biran, Andrew DeCastro, Dane R. Van Domelen, Ohad S. Bentur, Chris Zhang, Jatin J. Shah, Sharon Shacham, Michael G. Kauffman, Brea Lipe
Journal: Blood
Blood (2021) 138 (Supplement 1): 2751.
DOI: https://doi.org/10.1182/blood-2021-150998
Published: 2021
Journal Articles

Updated Results of a Phase 1/2 Clinical Study of Zinc Finger Nuclease-Mediated Editing of BCL11A in Autologous Hematopoietic Stem Cells for Transfusion-Dependent Beta Thalassemia

Mark C. Walters, Angela R. Smith, Gary J. Schiller, Erica B. Esrick, David A. Williams, Tatiana Gogoleva, Didier Rouy, Bettina M. Cockroft, Gregory M. Vercellotti
Journal: Blood
Blood (2021) 138 (Supplement 1): 3974.
DOI: https://doi.org/10.1182/blood-2021-147907
Published: 2021
Journal Articles

Gilteritinib (GILT) Monotherapy with Addition of Decitabine (DEC) in Non-Responders in Older Newly Diagnosed (ND) FLT3 Mutated Acute Myeloid Leukemia (AML) Patients Having High and Low Variant Allele Frequency (VAF): A Phase 2/1b Sub-Study of the Beat AML Master Trial

Elie Traer, Ying Huang, Alice S. Mims, Eytan M. Stein, Maria R. Baer, Wendy Stock, Tibor Kovacsovics, William Blum, Martha L. Arellano, Gary J. Schiller, Rebecca L. Olin, James M. Foran, Mark R. Litzow, Tara L. Lin, Prapti Patel, Matthew C. Foster, Robert L. Redner, Zeina Al-Mansour, Christopher R. Cogle, Michael M. Boyiadzis, Ronan Swords, Robert H. Collins, Jo-Anne Vergilio, Nyla A. Heerema, Leonard Rosenberg, Ashley O. Yocum, Sonja Marcus, Timothy Chen, Franchesca Druggan, Mona Stefanos, Theophilus J Gana, Abigail B. Shoben, Brian J. Druker, Amy Burd, John C. Byrd, Ross L. Levine, Uma Borate
Journal: Blood
Blood (2021) 138 (Supplement 1): 1277.
DOI: https://doi.org/10.1182/blood-2021-148207
Published: 2021
Journal Articles

Efficacy and Safety of Selinexor-Containing Regimens in Patients with Multiple Myeloma Previously Treated with Anti-CD38 Monoclonal Antibodies (αCD38 mAb)

Suzanne Lentzsch, Brea Lipe, Sascha A. Tuchman, Nizar J. Bahlis, William I. Bensinger, Michael Sebag, Heather J. Sutherland, Jorge Monge, Cristina J. Gasparetto, Muhamed Baljevic, Natalie S. Callander, Christopher P. Venner, Darrell J. White, Rami Kotb, Christine I. Chen, Gary J. Schiller, Sumit Madan, Richard Leblanc, Andrew DeCastro, Ohad S. Bentur, Jatin J. Shah, Dane R. Van Domelen, Michael G. Kauffman, Sharon Shacham, Noa Biran
Journal: Blood
Blood (2021) 138 (Supplement 1): 1651.
DOI: https://doi.org/10.1182/blood-2021-150232
Published: 2021
Journal Articles

Subgroup Analysis from a Phase 2 Study of the Efficacy and Safety of Parsaclisib, a Selective PI3Kδ Inhibitor, in Combination with Ruxolitinib in Patients with Myelofibrosis (MF)

Abdulraheem Yacoub, Uma Borate, Raajit Rampal, Haris Ali, Eunice S. Wang, Aaron T. Gerds, Gabriela Hobbs, Marina Kremyanskaya, Elliott Winton, Casey O'Connell, Swati Goel, Stephen Oh, Gary J. Schiller, Albert Assad, Sue Erickson-Viitanen, Feng Zhou, Naval Daver
Journal: Blood
Blood (2021) 138 (Supplement 1): 3647.
DOI: https://doi.org/10.1182/blood-2021-148668
Published: 2021
Journal Articles

Tagraxofusp (SL-401) in Patients with Chronic Myelomonocytic Leukemia (CMML): Updated Results of an Ongoing Phase 1/2 Trial

Mrinal M. Patnaik, Haris Ali, Eunice S. Wang, Abdulraheem Yacoub, Vikas Gupta, Sangmin Lee, Gary J. Schiller, James M. Foran, Ayalew Tefferi, Christopher L Brooks, Guillermo Garcia-Manero, Tariq I. Mughal, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 538.
DOI: https://doi.org/10.1182/blood-2021-147827
Published: 2021
Journal Articles

Early Clinical Evaluation of Potential Synergy of Targeted Radiotherapy with Lintuzumab-Ac225 and Venetoclax in Relapsed/Refractory AML

Gary J. Schiller, Laura Finn, Gail J. Roboz, Johnnie J. Orozco, Tiffany Lin, Mary M Chen, Mohamed M. Hegazi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3412.
DOI: https://doi.org/10.1182/blood-2021-146018
Published: 2021
Journal Articles

Venetoclax in Combination with Gilteritinib Demonstrates Molecular Clearance of FLT3 mutation in Relapsed/Refractory FLT3 -Mutated Acute Myeloid Leukemia

Naval Daver, Alexander E. Perl, Joseph Maly, Mark Levis, Ellen Ritchie, Mark R. Litzow, James McCloskey, Catherine C. Smith, Gary J. Schiller, Terrence Bradley, Ramon V. Tiu, Kiran Naqvi, Monique Dail, Satya Siddani, Jing Wang, Brenda Chyla, Paul Lee, Jessica K. Altman
Journal: Blood
Blood (2021) 138 (Supplement 1): 691.
DOI: https://doi.org/10.1182/blood-2021-150743
Published: 2021
Journal Articles

Integrated Safety Analysis of Tagraxofusp, a CD123-Directed Targeted Therapy, in Patients with Hematologic Malignancies

Naveen Pemmaraju, Hagop Kantarjian, Kendra Sweet, Eunice S. Wang, Andrew A. Lane, Haris Ali, Anthony S. Stein, Abdulraheem Yacoub, David A. Rizzieri, Sumithira Vasu, Vikas Gupta, Sangmin Lee, Gary J. Schiller, James M. Foran, Minakshi S. Taparia, Todd L. Rosenblat, Roland B. Walter, Debra Sieminski, Madhu Anant, Mrinal M. Patnaik, Tariq I. Mughal, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 2318.
DOI: https://doi.org/10.1182/blood-2021-145344
Published: 2021
Journal Articles

Gilteritinib Can be Safely Combined with Atezolizumab for the Treatment of Relapsed or Refractory FLT3 -Mutated AML: Results of a Phase 1 Study

Jessica K. Altman, Bhavana Bhatnagar, Sameem Abedin, Amanda Przespolewski, Prapti A. Patel, Gary J. Schiller, Stanley Gill, Dhruva Patel, Linyi Fan, Ramon V. Tiu, Stephen A. Strickland
Journal: Blood
Blood (2021) 138 (Supplement 1): 2343.
DOI: https://doi.org/10.1182/blood-2021-150707
Published: 2021
Journal Articles

A Phase 1/2 Study of Single Agent Tagraxofusp, a First-in-Class CD123-Targeted Therapy, in Patients with Myelofibrosis That Is Relapsed/Refractory Following JAK Inhibitor Therapy

Abdulraheem Yacoub, Mrinal M. Patnaik, Haris Ali, Eunice S. Wang, Vikas Gupta, Sangmin Lee, Gary J. Schiller, Minakshi S. Taparia, Animesh Pardanani, Ayalew Tefferi, Srdan Verstovsek, Joseph D. Khoury, Christopher L Brooks, Tariq I. Mughal, Naveen Pemmaraju
Journal: Blood
Blood (2021) 138 (Supplement 1): 140.
DOI: https://doi.org/10.1182/blood-2021-145276
Published: 2021
Journal Articles

Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study

Clinical Trials & Observations
Mitchell E. Horwitz, Patrick J. Stiff, Corey Cutler, Claudio Brunstein, Rabi Hanna, Richard T. Maziarz, Andrew R. Rezvani, Nicole A. Karris, Joseph McGuirk, David Valcarcel, Gary J. Schiller, Caroline A. Lindemans, William Y. K. Hwang, Liang Piu Koh, Amy Keating, Yasser Khaled, Nelson Hamerschlak, Olga Frankfurt, Tony Peled, Irit Segalovich, Beth Blackwell, Stephen Wease, Laurence S. Freedman, Einat Galamidi-Cohen, Guillermo Sanz
Journal: Blood
Blood (2021) 138 (16): 1429–1440.
DOI: https://doi.org/10.1182/blood.2021011719
Published: 2021
Includes: Supplemental data
Journal Articles

KTE-X19 anti-CD19 CAR T-cell therapy in adult relapsed/refractory acute lymphoblastic leukemia: ZUMA-3 phase 1 results

Clinical Trials & Observations
Bijal D. Shah, Michael R. Bishop, Olalekan O. Oluwole, Aaron C. Logan, Maria R. Baer, William B. Donnellan, Kristen M. O’Dwyer, Houston Holmes, Martha L. Arellano, Armin Ghobadi, John M. Pagel, Yi Lin, Ryan D. Cassaday, Jae H. Park, Mehrdad Abedi, Januario E. Castro, Daniel J. DeAngelo, Adriana K. Malone, Raya Mawad, Gary J. Schiller, John M. Rossi, Adrian Bot, Tong Shen, Lovely Goyal, Rajul K. Jain, Remus Vezan, William G. Wierda
Journal: Blood
Blood (2021) 138 (1): 11–22.
DOI: https://doi.org/10.1182/blood.2020009098
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase 1 Study of Gilteritinib in Combination with Induction and Consolidation Chemotherapy in Patients with Newly Diagnosed AML: Final Results

Keith W. Pratz, MD, Mohamad Cherry, MDMS, Jessica K. Altman, MD, Brenda W. Cooper, MD, Jose Carlos Cruz, MD, Joseph G. Jurcic, MD, Mark Levis, MD PhD, Tara Lin, MD, Alexander E. Perl, MD, Nikolai A. Podoltsev, MD PhD, Gary J. Schiller, MD, Jason E. Hill, PhD, Angela James, PhD, Qiaoyang Lu, MS, Ramon V. Tiu, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
DOI: https://doi.org/10.1182/blood-2020-137685
Published: 2020