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Journal Articles

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Blood (2019) 134 (Supplement_1): 1179.

DOI: https://doi.org/10.1182/blood-2019-124429

Published: 2019

Journal Articles

Temporal autoregulation during human PU.1 locus SubTAD formation

Daniel Schuetzmann, Carolin Walter, Boet van Riel, Sabrina Kruse, Thorsten König, Tabea Erdmann, Alexander Tönges, Eric Bindels, Andre Weilemann, Claudia Gebhard, Klaus Wethmar, Chiara Perrod, Julia Minderjahn, Michael Rehli, Ruud Delwel, Georg Lenz, Stefan Gröschel, Martin Dugas, Frank Rosenbauer

Blood (2018) 132 (25): 2643–2655.

DOI: https://doi.org/10.1182/blood-2018-02-834721

Published: 2018

Includes: Supplemental data

Journal Articles

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma

Blood (2017) 129 (1): 71–81.

DOI: https://doi.org/10.1182/blood-2016-02-700773

Published: 2017

Includes: Supplemental data

Journal Articles

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Isabell Schulze, Christian Rohde, Marina Scheller-Wendorff, Nicole Bäumer, Annika Krause, Friederike Herbst, Pia Riemke, Katja Hebestreit, Petra Tschanter, Qiong Lin, Heinz Linhart, Lucy A. Godley, Hanno Glimm, Martin Dugas, Wolfgang Wagner, Wolfgang E. Berdel, Frank Rosenbauer, Carsten Müller-Tidow

Blood (2016) 127 (12): 1575–1586.

DOI: https://doi.org/10.1182/blood-2015-07-655928

Published: 2016

Includes: Supplemental data

Journal Articles

Identification Of Leukemia Suppressive Genes By Inducible Overexpression Of The DNA Methyltransferase DNMT3B During Leukemogenesis In Mice

Isabell Schulze, Petra Tschanter, Christian Rohde, PhD, Annika Krause, Heinz Linhart, Katja Hebestreit, Martin Dugas, MD, Frank Rosenbauer, Wolfgang E. Berdel, MD, Carsten Müller-Tidow, MD

Blood (2013) 122 (21): 2493.

DOI: https://doi.org/10.1182/blood.V122.21.2493.2493

Published: 2013

Journal Articles

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Blood (2013) 121 (1): 178–187.

DOI: https://doi.org/10.1182/blood-2012-08-448860

Published: 2013

Includes: Supplemental data

Journal Articles

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Saeed Ghani, Pia Riemke, Jörg Schönheit, Dido Lenze, Jürgen Stumm, Maarten Hoogenkamp, Anne Lagendijk, Sven Heinz, Constanze Bonifer, Jeroen Bakkers, Salim Abdelilah-Seyfried, Michael Hummel, Frank Rosenbauer

Blood (2011) 118 (8): 2275–2284.

DOI: https://doi.org/10.1182/blood-2011-02-335141

Published: 2011

Includes: Supplemental data

Journal Articles

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Mathias Leddin, Chiara Perrod, Maarten Hoogenkamp, Saeed Ghani, Salam Assi, Sven Heinz, Nicola K. Wilson, George Follows, Jörg Schönheit, Lena Vockentanz, Ali M. Mosammam, Wei Chen, Daniel G. Tenen, David R. Westhead, Berthold Göttgens, Constanze Bonifer, Frank Rosenbauer

Blood (2011) 117 (10): 2827–2838.

DOI: https://doi.org/10.1182/blood-2010-08-302976

Published: 2011

Includes: Supplemental data

Journal Articles

A Distal Single Nucleotide Polymorphism Disrupts Development-Dependent Long-Range Transcriptional Regulation of the PU.1 Gene through the Chromatin-Remodeling Protein SATB1 in Acute Myeloid Leukemia.

Blood (2007) 110 (11): 3175.

DOI: https://doi.org/10.1182/blood.V110.11.3175.3175

Published: 2007

Journal Articles

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

Alex Ebralidze, PhD, Pu Zhang, MD, Frank Rosenbauer, Ph.D., Gang Huang, Ph.D., Ulrich Steidl, M.D., Tajhal Dayaram, B.S., Florence Guibal, Ph.D., Johanna Klupp, B.S., Dana Neel, Constanze Bonifer, Ph.D., Daniel G. Tenen, M.D.

Blood (2006) 108 (11): 781.

DOI: https://doi.org/10.1182/blood.V108.11.781.781

Published: 2006

Journal Articles

Complete Absence of the Lineage-Determining Transcription Factor C/EBPα Results in Loss of Myeloid Identity in Bcr/abl Induced Malignancy.

Katharina Wagner, MD, Pu Zhang, MD, Frank Rosenbauer, PhD, Bettina Drescher, PhD, Susumu Kobayashi, MD, Hanna S. Radomska, PhD, Jeffery L. Kutok, MD, Jürgen Krauter, MD, Daniel G. Tenen, MD

Blood (2005) 106 (11): 646.

DOI: https://doi.org/10.1182/blood.V106.11.646.646

Published: 2005

Journal Articles

Identification of ID4 as a Cooperating Second Hit for T Cell Lymphoma Development in PU.1 URE Δ/Δ Mice.

Bronwyn M. Owens, PhD, Li Yu, PhD, Ulrich Steidl, MD, Jeffrey L. Kutok, MD, Linda K. Clayton, PhD, Katharina Wagner, MD, Hiromi Iwasaki, MD, Chunhui Liu, Björn Hackanson, MD, Koichi Akashi, MD, Christoph Plass, PhD, Daniel G. Tenen, MD, Frank Rosenbauer, PhD

Blood (2005) 106 (11): 2613.

DOI: https://doi.org/10.1182/blood.V106.11.2613.2613

Published: 2005

Journal Articles

Essential Role of Jun Family Transcription Factors in PU.1-Induced Leukemic Stem Cell Transformation.

Ulrich Steidl, MD, PhD, Frank Rosenbauer, PhD, Roel G.W Verhaak, Xuesong Gu, PhD, Hasan H. Otu, PhD, Shakir Kolia, PhD, Bronwyn M. Owens, PhD, Steffen Klippel, PhD, Katharina Wagner, MD, Manuel Aivado, MD, Emmanuelle Passegue, PhD, Towia A. Libermann, PhD, Ruud Delwel, PhD, Daniel G. Tenen, MD

Blood (2005) 106 (11): 463.

DOI: https://doi.org/10.1182/blood.V106.11.463.463

Published: 2005

Journal Articles

Effect of transcription-factor concentrations on leukemic stem cells

Frank Rosenbauer, Steffen Koschmieder, Ulrich Steidl, Daniel G. Tenen

Blood (2005) 106 (5): 1519–1524.

DOI: https://doi.org/10.1182/blood-2005-02-0717

Published: 2005

Journal Articles

Deletion of a Key PU.1 Gene Regulatory Element Induces T-Cell Lymphoma.

Frank Rosenbauer, Ulrich Steidl, Bronwyn Owens, Linda Clayton, Katharina Wagner, Jeffery L. Kutok, Michelle M. Le Beau, Daniel G. Tenen

Blood (2004) 104 (11): 344.

DOI: https://doi.org/10.1182/blood.V104.11.344.344

Published: 2004

Journal Articles

Knockdown of the Transcription Factor PU.1 Causes Characteristic Transcriptional Changes in Hematopoietic Stem Cells Prior to Leukemic Transformation.

Ulrich Steidl, MD PhD, Frank Rosenbauer, PhD, Xuesong Gu, PhD, Bronwyn Owens, PhD, Steffen Klippel, PhD, Katharina Wagner, MD, Manuel Aivado, MD, Towia A. Libermann, PhD, Daniel G. Tenen, MD

Blood (2004) 104 (11): 1112.

DOI: https://doi.org/10.1182/blood.V104.11.1112.1112

Published: 2004

Journal Articles

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1

Frank Rosenbauer, Katharina Wagner, Pu Zhang, Klaus-Peter Knobeloch, Atsushi Iwama, Daniel G. Tenen

Blood (2004) 103 (11): 4294–4301.

DOI: https://doi.org/10.1182/blood-2003-08-2688

Published: 2004

Journal Articles

Accumulation of c-Cbl and rapid termination of colony-stimulating factor 1 receptor signaling in interferon consensus sequence binding protein–deficient bone marrow–derived macrophages

Axel Kallies, Frank Rosenbauer, Marina Scheller, Klaus-Peter Knobeloch, Ivan Horak

Blood (2002) 99 (9): 3213–3219.

DOI: https://doi.org/10.1182/blood.V99.9.3213

Published: 2002

Journal Articles

Interferon Consensus Sequence Binding Protein and Interferon Regulatory Factor-4/Pip Form a Complex That Represses the Expression of the Interferon-Stimulated Gene-15 in Macrophages

Frank Rosenbauer, Jeffrey F. Waring, John Foerster, Marcus Wietstruk, Dieter Philipp, Ivan Horak

Blood (1999) 94 (12): 4274–4281.

DOI: https://doi.org/10.1182/blood.V94.12.4274

Published: 1999

Journal Articles

Lack of Interferon Consensus Sequence Binding Protein ( ICSBP ) Transcripts in Human Myeloid Leukemias

Manuel Schmidt, Stefan Nagel, Jutta Proba, Christian Thiede, Markus Ritter, Jeffrey F. Waring, Frank Rosenbauer, Dieter Huhn, Burghardt Wittig, Ivan Horak, Andreas Neubauer

Blood (1998) 91 (1): 22–29.

DOI: https://doi.org/10.1182/blood.V91.1.22

Published: 1998

NARROW

Deconvolution of Hematopoietic Commitment Decisions By Genome-Wide Analysis of Progressive DNA Methylation Changes

Temporal autoregulation during human PU.1 locus SubTAD formation

Pharmacological restoration and therapeutic targeting of the B-cell phenotype in classical Hodgkin lymphoma

Increased DNA methylation of Dnmt3b targets impairs leukemogenesis

Identification Of Leukemia Suppressive Genes By Inducible Overexpression Of The DNA Methyltransferase DNMT3B During Leukemogenesis In Mice

DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding

Macrophage development from HSCs requires PU.1-coordinated microRNA expression

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

A Distal Single Nucleotide Polymorphism Disrupts Development-Dependent Long-Range Transcriptional Regulation of the PU.1 Gene through the Chromatin-Remodeling Protein SATB1 in Acute Myeloid Leukemia.

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

Complete Absence of the Lineage-Determining Transcription Factor C/EBPα Results in Loss of Myeloid Identity in Bcr/abl Induced Malignancy.

Identification of ID4 as a Cooperating Second Hit for T Cell Lymphoma Development in PU.1 URE Δ/Δ Mice.

Essential Role of Jun Family Transcription Factors in PU.1-Induced Leukemic Stem Cell Transformation.

Effect of transcription-factor concentrations on leukemic stem cells

Deletion of a Key PU.1 Gene Regulatory Element Induces T-Cell Lymphoma.

Knockdown of the Transcription Factor PU.1 Causes Characteristic Transcriptional Changes in Hematopoietic Stem Cells Prior to Leukemic Transformation.

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1

Accumulation of c-Cbl and rapid termination of colony-stimulating factor 1 receptor signaling in interferon consensus sequence binding protein–deficient bone marrow–derived macrophages

Interferon Consensus Sequence Binding Protein and Interferon Regulatory Factor-4/Pip Form a Complex That Represses the Expression of the Interferon-Stimulated Gene-15 in Macrophages

Lack of Interferon Consensus Sequence Binding Protein ( ICSBP ) Transcripts in Human Myeloid Leukemias

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American Society of Hematology

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ASH Publications

American Society of Hematology

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