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Francisco Adrian
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Journal Articles

Activation of Lysosomal Function and Reactive Oxygen Species Play Crucial Roles in SAR650984-Induced Direct Killing of Human Multiple Myeloma Cells with Mutated p53, Which Is Further Augmented By Pomalidomide

Hua Jiang, MDPhD, Chirag Acharya, MD, Gang An Gang An, MDPhD, Xiaoyan Feng, MD, Zhili Song, Guang Yang, PhD, Francisco Adrian, Lugui Qiu, MD, Paul Richardson, MD, Nikhil C. Munshi, MD, Yu-Tzu Tai, PhD, Kenneth C Anderson, MD
Journal: Blood
Blood (2015) 126 (23): 4253.
https://doi.org/10.1182/blood.V126.23.4253.4253
Published: 2015
Journal Articles

SAR650984 (SAR) Directly Promotes Homotypic Adhesion-Related Multiple Myeloma (MM) Cell Death and SAR-Induced Anti-MM Activities Are Enhanced By Pomalidomide, More Potently Than Lenalidomide

Hua Jiang, MDPhD, Gang An, MD PhD, Chirag Acharya, MD, Mike Y Zhong, BS, Ti Cai, PhD, Zhili Song, Guang Yang, Francisco Adrian, PhD, Nikhil C. Munshi, MD, Yu-Tzu Tai, PhD, Kenneth C. Anderson
Journal: Blood
Blood (2014) 124 (21): 2124.
https://doi.org/10.1182/blood.V124.21.2124.2124
Published: 2014
Journal Articles

SAR 650984, a Therapeutic Anti-CD38 Monoclonal Antibody, Blocks CD38-CD31 Interaction in Multiple Myeloma

Gang An, MD PhD, Hua Jiang, MDPhD, Chirag Acharya, MD, Mike Y Zhong, BS, Ti Cai, PhD, Guang Yang, Zhili Song, Joachim Theilhaber, PhD, Francisco Adrian, PhD, Yu-Tzu Tai, PhD, Kenneth C. Anderson, MD
Journal: Blood
Blood (2014) 124 (21): 4729.
https://doi.org/10.1182/blood.V124.21.4729.4729
Published: 2014
Journal Articles

PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene

Zhuyan Guo, Anlai Wang, Weidong Zhang, Mikhail Levit, Qiang Gao, Claude Barberis, Michel Tabart, Jingxin Zhang, Dietmar Hoffmann, Dmitri Wiederschain, Jennifer Rocnik, Fangxian Sun, Josh Murtie, Christoph Lengauer, Stefan Gross, Bailin Zhang, Hong Cheng, Vinod Patel, Laurent Schio, Francisco Adrian, Marion Dorsch, Carlos Garcia-Echeverria, Shih-Min A. Huang
Journal: Blood
Blood (2014) 124 (11): 1777–1789.
https://doi.org/10.1182/blood-2014-01-551234
Published: 2014
Includes: Supplemental data
Journal Articles

ITK-SYK Induces T-Cell Lymphoma with Accompanying Inflammatory Disease in Mice.

Christine Dierks, MD, Hong Ma, Hendrik Veelken, Markus Warmuth, MD, Francisco Adrian, PhD
Journal: Blood
Blood (2007) 110 (11): 693.
https://doi.org/10.1182/blood.V110.11.693.693
Published: 2007