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Journal Articles

MRD dynamics during maintenance for improved prognostication of 1280 patients with myeloma in the TOURMALINE-MM3 and -MM4 trials

Clinical Trials & Observations
Bruno Paiva, Irene Manrique, Meletios A. Dimopoulos, Francesca Gay, Chang-Ki Min, Sonja Zweegman, Ivan Špička, Raphael Teipel, María-Victoria Mateos, Nicola Giuliani, Michele Cavo, Christine Rojas Hopkins, Weijun Fu, Kaveri Suryanarayan, Alexander Vorog, Cong Li, Bingxia Wang, Jose Estevam, Richard Labotka, Ajeeta B. Dash
Journal: Blood
Blood (2023) 141 (6): 579–591.
https://doi.org/10.1182/blood.2022016782
Published: 2023
Includes: Supplemental data
Journal Articles

Co-Occurrence of High-Risk Lesions Is a Consistent Predictor of Ultra-High Risk Multiple Myeloma in Newly Diagnosed and Relapsed/Refractory Patients - Meta-Analysis of 5,808 Trial Patients

Martin F. Kaiser, Pieter Sonneveld, David Cairns, Marc S Raab, Alessandra Larocca, Sarah R Brown, Marc-A. Baertsch, Cong Li, Pellegrino Musto, Kwee Yong, Elias K Mai, Andrea Capra, Gordon Cook, Hartmut Goldschmidt, Mario Boccadoro, Graham Jackson, Niels Weinhold, Francesca Gay
Journal: Blood
Blood (2022) 140 (Supplement 1): 1556–1558.
https://doi.org/10.1182/blood-2022-160130
Published: 2022
Journal Articles

Efficacy of Daratumumab Combined with Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting with Extramedullary Disease: A European Myeloma Network Study (EMN19)

Meral Beksac, Tulin Tuglular, Francesca Gay, Roberto Mina, Eirini Katodritou, Ali Unal, Michele Cavo, Guner Hayri Ozsan, Vincent H.J. van der Velden, Berna Beverloo, Michael Vermeulen, Mark van Duin, Guldane Cengiz, Omur Gokmen Sevindik, Serena Merante, Kyriaki Manousou, Pieter Sonneveld, Evangelos Terpos
Journal: Blood
Blood (2022) 140 (Supplement 1): 10177–10179.
https://doi.org/10.1182/blood-2022-160004
Published: 2022
Journal Articles

Single-Cell Transcriptomic Analysis Reveals Reduction of Cytotoxic NK Cells in a Subset of Newly Diagnosed Multiple Myeloma Patients Impacting Outcome after Daratumumab Therapy

Sabrin Tahri, Madelon M.E. de Jong, Cathelijne Fokkema, Natalie Papazian, Zoltan Kellermayer, Michael Vermeulen, Mark van Duin, Pieter van de Woestijne, Kazem Nasserinejad, Elona Saraci, Mattia D'Agostino, Francesca Gay, Vincent H.J. van der Velden, Niels WCJ Van De Donk, Annemiek Broijl, Pieter Sonneveld, Sonja Zweegman, Tom Cupedo
Journal: Blood
Blood (2022) 140 (Supplement 1): 9982–9984.
https://doi.org/10.1182/blood-2022-164812
Published: 2022
Journal Articles

Treatment of Primary Plasma Cell Leukemia with Carfilzomib and Lenalidomide-Based Therapy: Results of the Final Analysis of the Prospective Phase 2 EMN12/HOVON-129 Study for Patients Aged 18-65 Years

Niels W.C.J. Van De Donk, Monique C. Minnema, Bronno van der Holt, Fredrik Schjesvold, Ka Lung Wu, Andrea Capra, Annemiek Broijl, Wilfried W.H. Roeloffzen, Alain Gadisseur, Giuseppe Pietrantuono, Ludek Pour, Vincent H.J. van der Velden, Thomas Lund, Massimo Offidani, Mariella Grasso, Luisa Giaccone, Michele Cavo, Trine Silkjaer, Jo Caers, Sonja Zweegman, Roman Hájek, Reuben Benjamin, Annette Juul Vangsted, Mario Boccadoro, Francesca Gay, Pieter Sonneveld, Pellegrino Musto
Journal: Blood
Blood (2022) 140 (Supplement 1): 4420–4422.
https://doi.org/10.1182/blood-2022-165942
Published: 2022
Journal Articles

Combining Plasma Cell Leukemia-like Status with the Second Revision of the International Staging System Improves Risk Classification

Davine Hofste op Bruinink, Rowan Kuiper, Mark van Duin, Tom Cupedo, Vincent H.J. van der Velden, Remco Hoogenboezem, Bronno van der Holt, Berna Beverloo, Erik T. Valent, Michael Vermeulen, Mattia D'Agostino, Francesca Gay, Annemiek Broijl, Herve Avet-Loiseau, Nikhil C Munshi, Pellegrino Musto, Philippe Moreau, Sonja Zweegman, Niels W.C.J. van de Donk, Pieter Sonneveld
Journal: Blood
Blood (2022) 140 (Supplement 1): 1566–1567.
https://doi.org/10.1182/blood-2022-170249
Published: 2022
Journal Articles

DVRd Followed By Ciltacabtagene Autoleucel Versus DVRd Followed By ASCT in Patients with Newly Diagnosed Multiple Myeloma Who Are Transplant Eligible: A Randomized Phase 3 Study ( EM agine/CARTITUDE-6)

Mario Boccadoro, Jesús San-Miguel, Kenshi Suzuki, Niels W.C.J. Van De Donk, Gordon Cook, Andrzej Jakubowiak, Deepu Madduri, Salma Afifi, An-Sofie Stevens, Jordan M. Schecter, William Deraedt, Steven Kuppens, Pankaj Mistry, Lida Pacaud, Erika Florendo, Annemiek Broijl, Francesca Gay, Roberto Mina, Leo Rasche, Philippe Moreau, María-Victoria Mateos, Hermann Einsele, Pieter Sonneveld
Journal: Blood
Blood (2022) 140 (Supplement 1): 4630–4632.
https://doi.org/10.1182/blood-2022-157021
Published: 2022
Journal Articles

LocoMMotion: A Prospective, Non-Interventional, Multinational Study of Real-Life Current Standards of Care in Patients With Relapsed/Refractory Multiple Myeloma Who Received ≥3 Prior Lines of Therapy

Philippe Moreau, Katja Weisel, Valerio De Stefano, Hartmut Goldschmidt, Michel Delforge, Mohamad Mohty, Michele Cavo, Ravi Vij, Joanne Lindsey-Hill, Dominik Dytfeld, Emanuele Angelucci, Aurore Perrot, Reuben Benjamin, Niels W.C.J. Van de Donk, Enrique Ocio, Christof Scheid, Francesca Gay, Wilfried Roeloffzen, Paula Rodriguez-Otero, Annemiek Broyl, Anna Potamianou, Caline Sakabedoyan, Maria Semerjian, Sofia Keim, Vadim Strulev, Jordan M. Schecter, Martin Vogel, Robert Wapenaar, Tonia Nesheiwat, Jesus San-Miguel, Pieter Sonneveld, Hermann Einsele, Maria-Victoria Mateos
Journal: Blood
Blood (2021) 138 (Supplement 1): 3057.
https://doi.org/10.1182/blood-2021-146188
Published: 2021
Journal Articles

Modified Delphi Method Identifies Consensus Areas for Routine Minimal Residual Disease Testing in Multiple Myeloma

Karthik Ramasamy, Hervé Avet-Loiseau, Cecilie Hveding Blimark, Michel Delforge, Francesca Gay, Salomon Manier, Joaquin Martinez-Lopez, Maria-Victoria Mateos, Mohamad Mohty, Niels W.C.J. van de Donk, Katja Weisel
Journal: Blood
Blood (2021) 138 (Supplement 1): 1631.
https://doi.org/10.1182/blood-2021-144578
Published: 2021
Journal Articles

Safety of Daratumumab Combined with Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Patients with Multiple Myeloma Presenting with Extramedullary Disease during the COVID-19 Pandemic

Meral Beksac, Tulin Tuglular, Ali Unal, Michele Cavo, Francesca Gay, Eirini Katodritou, Guner Hayri Ozsan, Guldane Cengiz, Omur Gokmen Sevindik, Serena Merante, Kyriaki Manousou, Pieter Sonneveld, Evangelos Terpos
Journal: Blood
Blood (2021) 138 (Supplement 1): 1657.
https://doi.org/10.1182/blood-2021-152444
Published: 2021
Journal Articles

Meta-Analysis of Ciltacabtagene Autoleucel Versus Physician's Choice in the Treatment of Patients with Relapsed or Refractory Multiple Myeloma

Parameswaran Hari, Jesus G. Berdeja, Valerio De Stefano, Francesca Gay, Becky Hooper, Anja Haltner, Shaji Kumar, Thomas Martin, Maria-Victoria Mateos, Philippe Moreau, Emily Rosta, Imtiaz A. Samjoo, Saad Z. Usmani, Katja Weisel, Carolyn C. Jackson, Yunsi Olyslager, Jordan M. Schecter, Martin Vogel, Ashraf Garrett, Sam Lee, Tonia Nesheiwat, Lida Pacaud, Changwei Zhou, Satish Valluri, Luciano J. Costa, Yi Lin
Journal: Blood
Blood (2021) 138 (Supplement 1): 1676.
https://doi.org/10.1182/blood-2021-146177
Published: 2021
Journal Articles

Can Patient-Reported Ocular Symptoms Guide Dose Modifications in Patients with Relapsed/Refractory Multiple Myeloma Receiving Belantamab Mafodotin?

Rakesh Popat, Ashraf Z. Badros, Shaji Kumar, Paula Rodríguez-Otero, Adam D. Cohen, Salomon Manier, Peter M. Voorhees, Francesca Gay, Robert M. Rifkin, Thomas Martin, Ajai Chari, Katja Weisel, Asim V. Farooq, Bennie H. Jeng, Wee Joo Chng, Hans C. Lee, Jesus Berdeja, Vinay Jadhav, Alessandra Tosolini, Laurie Eliason, Antonio Palumbo, Meletios A. Dimopoulos, Sagar Lonial, Suzanne Trudel, Paul G. Richardson, Evangelos Terpos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2746.
https://doi.org/10.1182/blood-2021-152681
Published: 2021
Journal Articles

Clinical features associated with COVID-19 outcome in multiple myeloma: first results from the International Myeloma Society data set

Clinical Trials & Observations
Ajai Chari, Mehmet Kemal Samur, Joaquin Martinez-Lopez, Gordon Cook, Noa Biran, Kwee Yong, Vania Hungria, Monika Engelhardt, Francesca Gay, Ana García Feria, Stefania Oliva, Rimke Oostvogels, Alessandro Gozzetti, Cara Rosenbaum, Shaji Kumar, Edward A. Stadtmauer, Hermann Einsele, Meral Beksac, Katja Weisel, Kenneth C. Anderson, María-Victoria Mateos, Philippe Moreau, Jesus San-Miguel, Nikhil C. Munshi, Hervé Avet-Loiseau
Journal: Blood
Blood (2020) 136 (26): 3033–3040.
https://doi.org/10.1182/blood.2020008150
Published: 2020
Includes: Supplemental data
Journal Articles

Impact of Gain and Amplification of 1q in Newly Diagnosed Multiple Myeloma Patients Receiving Carfilzomib-Based Treatment in the Forte Trial

Mattia D'Agostino, MD, Marina Ruggeri, Sara Aquino, Nicola Giuliani, Maddalena Arigoni, Massimo Gentile, Martina Olivero, Iolanda Donatella Vincelli, Andrea Capra, Chiara Mussatto, Antonio Ledda, Paola Tacchetti, Caterina Musolino, Claudia Cellini, Francesca Patriarca, Stelvio Ballanti, Raffaele Calogero, Pellegrino Musto, Mario Boccadoro, Francesca Gay, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 38–40.
https://doi.org/10.1182/blood-2020-137060
Published: 2020
Journal Articles

Survival Analysis of Newly Diagnosed Transplant-Eligible Multiple Myeloma Patients in the Randomized Forte Trial

Francesca Gay, MD, Pellegrino Musto, Delia Rota Scalabrini, Monica Galli, Angelo Belotti, Elena Zamagni, Luca Bertamini, MD, Renato Zambello, Micol Quaresima, Giovanni De Sabbata, Giuseppe Pietrantuono, Mattia D'Agostino, MD, Daniela Oddolo, Andrea Capra, Anna Marina Liberati, Salvatore Palmieri, Franco Narni, Massimo Offidani, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–37.
https://doi.org/10.1182/blood-2020-136907
Published: 2020
Journal Articles

Upfront Autologous Hematopoietic Stem-Cell Transplantation Improves Overall Survival in Comparison with Bortezomib-Based Intensification Therapy in Newly Diagnosed Multiple Myeloma: Long-Term Follow-up Analysis of the Randomized Phase 3 EMN02/HO95 Study

Michele Cavo, Francesca Gay, MD, Meral Beksac, MD, Meletios A Dimopoulos, Lucia Pantani, MD PhD, Maria Teresa Petrucci, Luca Dozza, MSc, Bronno Van Der Holt, PhD, Sonja Zweegman, MDPhD, Elena Zamagni, Giuseppe A. Palumbo, MD PhD, Francesca Patriarca, Monica Galli, Vladimir Maisnar, MD PhD MBA, Markus Hansson, MD, Angelo Belotti, Ludek Pour, MD, Paula F Ypma, MD PhD, Mariella Grasso, Sandra Croockewit, MD, Massimo Offidani, Renato Zambello, Anna Marina Liberati, MD, Niels Frost Andersen, MD PhD, Annemiek Broyl, MD PhD, Rossella Troia, PharmD, Pellegrino Musto, Heinz Ludwig, MD, Anna Maria Morelli, MD, Roman Hajek, MD, Christoph Driessen, MD, Anders Waage, MD PhD, Peter Gimsing, DO, PhD, Ulf-Henrik Mellqvist, MD PhD, Thilo Zander, MD, Mario Boccadoro, Pieter Sonneveld, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-137575
Published: 2020
Journal Articles

Poor Prognosis of Multiple Myeloma Predicted By High Levels of Circulating Plasma Cells Is Independent from Other High-Risk Features but Is Modulated By the Achievement of Minimal Residual Disease Negativity

Luca Bertamini, MD, Mariella Grasso, Mattia D'Agostino, MD, Anna Pascarella, Patrizia Tosi, Federico Monaco, Francesco Pisani, Paola Bertazzoni, Milena Gilestro, Andrea Capra, Piero Galieni, Ombretta Annibali, Vincenzo Pavone, Stefano Molica, MD, Sonia Ronconi, Paola Tacchetti, Pellegrino Musto, Francesca Gay, MD, Mario Boccadoro, Stefania Oliva
Journal: Blood
Blood (2020) 136 (Supplement 1): 12–13.
https://doi.org/10.1182/blood-2020-137075
Published: 2020
Journal Articles

Consolidation Treatment with VRD Followed By Maintenance Therapy Versus Maintenance Alone in Newly Diagnosed, Transplant-Eligible Patients with Multiple Myeloma (MM): A Randomized Phase 3 Trial of the European Myeloma Network (EMN02/HO95)

Pieter Sonneveld, MD PhD, Meral Beksac, MD, Bronno Van Der Holt, PhD, Meletios A Dimopoulos, Angelo Michele Carella, MD, Heinz Ludwig, MD, Sonja Zweegman, MD PhD, Thilo Zander, MD, Ruth Wester, MD, Roman Hajek, MD, Lucia Pantani, MD PhD, Luca Dozza, MSc, Francesca Gay, MD, Anna Maria Cafro, Luca De Rosa, Francesca Fioritoni, MD, Ulf-Henrik Mellqvist, MD PhD, Rossella Troia, PharmD, Niels Frost Andersen, MD PhD, Ka Lung Wu, MD PhD, Christoph Driessen, MD, Susana Carvalho, MD, Alexandra J. Croockewit, MD PhD, Fredrik Schjesvold, MDPhD, Massimo Offidani, Michele Cavo, Mario Boccadoro
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–48.
https://doi.org/10.1182/blood-2020-139337
Published: 2020
Journal Articles

Impact of Imaging FDG-PET/CT Minimal Residual Disease Assessment on Outcomes and Matching with Bone Marrow Techniques in Newly Diagnosed Transplant Eligible Multiple Myeloma (MM) Patients: Results of the Phase II Randomized Forte Trial

Elena Zamagni, Cristina Nanni, MD, Francesca Gay, MD, Luca Dozza, MSc, Delia Rota Scalabrini, Mattia D'Agostino, MD, Rossella Ribolla, MD, Monica Galli, Manuela Racca, MD, Renato Zambello, Elena Rivolti, MD, Domenico Albano, MD, Annibale Versari, MD, Mariella Grasso, Rossella Troia, PharmD, Antonio Spadano, Francesca Patriarca, Marina Ruggeri, Marco Rensi, MD, Anna Pascarella, Pietro Zucchetta, MD, Paola Tacchetti, Stefano Fanti, MD PhD, Mario Boccadoro, Michele Cavo, Pellegrino Musto, Stefania Oliva
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
https://doi.org/10.1182/blood-2020-137412
Published: 2020
Journal Articles

Impact of Minimal Residual Disease (MRD) By Multiparameter Flow Cytometry (MFC) and Next-Generation Sequencing (NGS) on Outcome: Results of Newly Diagnosed Transplant-Eligible Multiple Myeloma (MM) Patients Enrolled in the Forte Trial

Stefania Oliva, Elisa Genuardi, Maria Teresa Petrucci, Mattia D'Agostino, MD, Daniel Auclair, Antonio Spadano, Allison P. Jacob, Michele Cea, Luca De Rosa, Alessandro Gozzetti, Marina Ruggeri, Andrea Capra, Milena Gilestro, Norbert Pescosta, Angelo D. Palmas, Agostina Siniscalchi, Ilan R. Kirsch, Paolo Corradini, Pellegrino Musto, Mario Boccadoro, Elena Zamagni, Francesca Gay, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-137351
Published: 2020