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Françoise Huguet
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Journal Articles

Determinants of Isolated CNS Relapse in Adults with Philadelphia-Negative Acute Lymphoblastic Leukemia. from Graall-2005 to -2014 Trials

Nicolas Boissel, Emilie Lemasle, Sylvain Chantepie, Thibaut Leguay, Corentin Orvain, Françoise Huguet, Yosr Hicheri, Nathalie Dhédin, Patrice Chevallier, Marie Balsat, Sébastien Maury, Hunault-Berger Mathilde, Karin Bilger, Eolia Brissot, Sebastian Wittnebel, Julie Guerder, Sarah Bonnet, Pascal Turlure, Anne Huynh, Claire Bories, Michael Gregor, Natacha Mauz, Ahmad Aljijakli, Carlos Graux, Yves Chalandon, Norbert Ifrah, Vahid Asnafi, Emmanuelle Clappier, Véronique Lheritier, Hervé Dombret
Journal: Blood
Blood (2024) 144 (Supplement 1): 731.
https://doi.org/10.1182/blood-2024-198614
Published: 2024
Journal Articles

Switch of Asparaginase Formulation Based on Antibody Monitoring in Adults with Philadelphia-Negative Adult Lymphoblastic Leukemia. Results of the Graall-2014 Trial

Marie Balsat, Corentin Orvain, Jean-François Benoist, Nicolas De Roux, Thibaut Leguay, Françoise Huguet, Patrice Chevallier, Cendrine Josson, Christine Bain-Wendlinger, Yosr Hicheri, Anne Thiebaut, Martine Escoffre-Barbe, Thomas Cluzeau, Florence Pasquier, Ana Berceanu, Florence Van Obbergh, Jamilé Frayfer, Gaëlle Guillerm, Victoria Cacheux, Isabelle Plantier, Laurence Sanhes, Chantal Himberlin, Jacques Vargaftig, Sabine Tricot, Yves Chalandon, Carlos Graux, Véronique Lheritier, Hervé Dombret, Hunault-Berger Mathilde, Nicolas Boissel
Journal: Blood
Blood (2024) 144 (Supplement 1): 1434.
https://doi.org/10.1182/blood-2024-199110
Published: 2024
Journal Articles

18-Months Follow-up of the Trial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Ame, Marion Simonet, Hyacinthe A Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Charlotte Doublet, Stéphane Morisset, Romaine Mayet, Gwenaëlle Garin, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2024) 144 (Supplement 1): 478.
https://doi.org/10.1182/blood-2024-198903
Published: 2024
Journal Articles

Single-Agent Subcutaneous Blinatumomab for Advanced B-Cell Acute Lymphoblastic Leukemia: Long-Term Follow-up from a Phase 1b Dose Expansion Cohort

Elias Jabbour, Gerhard Zugmaier, Pilar Martinez Sanchez, Jose J. Rifon, Vaibhav Agrawal, Ryan D Cassaday, Thomas Cluzeau, Françoise Huguet, Vladan Vucinic, Boris Böll, Anita W. Rijneveld, Mar Tormo, Maher Abdul-Hay, Paul R Gordon, Alessandro Rambaldi, Hagop M. Kantarjian
Journal: Blood
Blood (2024) 144 (Supplement 1): 1440.
https://doi.org/10.1182/blood-2024-205662
Published: 2024
Journal Articles

NGS-based stratification refines the risk stratification in T-ALL and identifies a very-high-risk subgroup of patients

Clinical Trials & Observations
Mathieu Simonin, Loïc Vasseur, Etienne Lengliné, Ludovic Lhermitte, Aurélie Cabannes-Hamy, Marie Balsat, Aline Schmidt, Marie-Emilie Dourthe, Aurore Touzart, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Françoise Huguet, Stéphane Ducassou, Véronique Lhéritier, Yves Chalandon, Norbert Ifrah, Hervé Dombret, Elizabeth Macintyre, Arnaud Petit, Philippe Rousselot, Jérôme Lambert, André Baruchel, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (15): 1570–1580.
https://doi.org/10.1182/blood.2023023754
Published: 2024
Includes: Supplemental data
Journal Articles

Genomic imbalance analysis provides new insight into prognostic factors in adult and pediatric T-ALL

Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe, Patrick Villarese, Stéphane Ducassou, Isabelle Arnoux, Jean-Michel Cayuela, Marie Balsat, Lucien Courtois, Guillaume Andrieu, Aurore Touzart, Françoise Huguet, Arnaud Petit, Norbert Ifrah, Hervé Dombret, André Baruchel, Elizabeth Macintyre, Claude Preudhomme, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2024) 144 (9): 988–1000.
https://doi.org/10.1182/blood.2023022154
Published: 2024
Includes: Supplemental data
Journal Articles

Nilotinib with or without cytarabine for Philadelphia-positive acute lymphoblastic leukemia

Clinical Trials & Observations
Yves Chalandon, Philippe Rousselot, Sylvie Chevret, Jean-Michel Cayuela, Rathana Kim, Françoise Huguet, Patrice Chevallier, Carlos Graux, Anne Thiebaut-Bertrand, Sylvain Chantepie, Xavier Thomas, Laure Vincent, Céline Berthon, Yosr Hicheri, Emmanuel Raffoux, Martine Escoffre-Barbe, Isabelle Plantier, Magalie Joris, Pascal Turlure, Florence Pasquier, Amine Belhabri, Gabrielle Roth Guepin, Sabine Blum, Michael Gregor, Marina Lafage-Pochitaloff, Julie Quessada, Véronique Lhéritier, Emmanuelle Clappier, Nicolas Boissel, Hervé Dombret
Journal: Blood
Blood (2024) 143 (23): 2363–2372.
https://doi.org/10.1182/blood.2023023502
Published: 2024
Includes: Supplemental data
Journal Articles

Genetic alterations and MRD refine risk assessment for KMT2A -rearranged B-cell precursor ALL in adults: a GRAALL study

Rathana Kim, Hugo Bergugnat, Cédric Pastoret, Florence Pasquier, Emmanuel Raffoux, Lise Larcher, Marie Passet, Nathalie Grardel, Eric Delabesse, Susanne Kubetzko, Aurélie Caye-Eude, Claus Meyer, Rolf Marschalek, Marine Lafage-Pochitaloff, Anne Thiebaut-Bertrand, Marie Balsat, Martine Escoffre-Barbe, Sabine Blum, Michael Baumann, Anne Banos, Nicole Straetmans, Maria-Pilar Gallego-Hernanz, Yves Chalandon, Carlos Graux, Jean Soulier, Thibaut Leguay, Mathilde Hunault, Françoise Huguet, Véronique Lhéritier, Hervé Dombret, Nicolas Boissel, Emmanuelle Clappier
Journal: Blood
Blood (2023) 142 (21): 1806–1817.
https://doi.org/10.1182/blood.2023021501
Published: 2023
Includes: Supplemental data
Journal Articles

Combination Chemotherapy in Patients with Newly Diagnosed Blastic Plasmacytoid Dendritic Cell Neoplasms (BPDCN): First Results of a Prospective French Trial (LpDessai)

Eric Deconinck, Berengere Gruson, Sabeha Biichle, Anne Roggy, Florian Renosi, Thomas Fournet, Maxime Desmarets, Gregory Tio, Tony Marchand, Mikael Roussel, Thibaut Leguay, Jean-Philippe Vial, Francoise Huguet, Francois Vergez, Emilie Chalayer, Khaoula Mahfoudi, Fressia Honeyman, Sebastien Maury, Nicolas Freynet, Caroline Bonmati, Veronique Latger-Cannard, Eve Gehlkopf, Caroline Bret, Damien Roos Weil, Magali Le Garff-Tavernier, Sophie Rigaudeau, Gandhi Laurent Damaj, Edouard Cornet, Remy Gressin, Marie-Christine Jacob, Delphine Martineau, Aguirre Mimoun, Alice Garnier, Marion Eveillard, Alban Villate, Emmanuelle Rault, Fanny Delettre, Francine Garnache Ottou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1516.
https://doi.org/10.1182/blood-2023-173379
Published: 2023
Journal Articles

Characteristics, Outcomes, Tfr Rates in Young Adults with Chronic Myeloid Leukemia in the Tyrosine Kinase Inhibitor Era: A French Observational Study

Laurence Legros, Francoise Huguet, Pascale Cony-Makhoul, Irit Touitou, Franck E. Nicolini, Delphine Rea, Marc G. Berger, Madalina Uzunov, Lydia Roy, Martine Escoffre Barbe, Agnes Guerci Bresler, Gabriel Etienne, Elisabeth Daguenet, Amelie Penot, Martine Gardembas Pain, Shanti Ame, Eric Jourdan, Hyacinthe A. Johnson-Ansah, Valerie Coiteux, Antoine Machet, Eric Lippert, Anne Vekoff, Jean Michel Karsenti, Stéphane Morisset, Francois Mahon
Journal: Blood
Blood (2023) 142 (Supplement 1): 1800.
https://doi.org/10.1182/blood-2023-173132
Published: 2023
Journal Articles

Treatment-Free Remission after Ponatinib Cessation in Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Patients. the Ponastop Observational Study

Franck E. Nicolini, Elisabetta Abruzzese, Gabrielle Roth-Guepin, Rami Abi-Tayeh, Vincent Alcazer, Sandrine Hayette, Stéphane Morisset, Françoise Huguet, Miriam Iezza, Fausto Castagnetti, Delphine Rea
Journal: Blood
Blood (2023) 142 (Supplement 1): 1799.
https://doi.org/10.1182/blood-2023-178326
Published: 2023
Journal Articles

Deep and Durable Cytogenetic and Molecular Responses with Pemigatinib in Myeloid/Lymphoid Neoplasms with Fibroblast Growth Factor Receptor 1 Rearrangement: The Fight-203 Study

Andreas Reiter, Jean-Jacques Kiladjian, Jay L. Patel, William Shomali, Alessandro Rambaldi, Srdan Verstovsek, Stephen Oh, Kensuke Usuki, Claire N Harrison, Ellen K. Ritchie, Luke P. Akard, Juan Carlos Hernandez Boluda, Françoise Huguet, Natalia Oliveira, Huiling Zhen, Tracy I. George, Philomena Colucci, Aidan Gilmartin, Jason Gotlib, Alessandro M. Vannucchi
Journal: Blood
Blood (2023) 142 (Supplement 1): 4551.
https://doi.org/10.1182/blood-2023-180945
Published: 2023
Journal Articles

Frontline Consolidation with Nelarabine for Adults with High-Risk T-Cell Acute Lymphoblastic Leukemia. Results of the Graall-2014/T Atriall Phase 2 Study

Nicolas Boissel, Carlos Graux, Francoise Huguet, Florence Pasquier, Aurore Touzart, Thomas Cluzeau, Ludovic Lhermitte, Eric Delabesse, Patrice Chevallier, Mathilde Hunault, Cedric Pastoret, Sebastien Maury, Nathalie Grardel, Martine Escoffre Barbe, Pascal Turlure, Beat Schafer, Marie Balsat, Philippe Rousselot, Thibaut Leguay, Eric Jourdan, Delphine Pranger, Michael Gregor, Emilie Lemasle, Anne Marie Ronchetti, Ana Berceanu, Ingrid Lafon, Madalina Uzunov, Etienne Lengline, Norbert Ifrah, Yves Chalandon, Véronique Lhéritier, Vahid Asnafi, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 962.
https://doi.org/10.1182/blood-2023-177696
Published: 2023
Journal Articles

NGS-Based Stratification Refines the Risk Stratification in T-ALL and Identifies a Very High-Risk Subgroup of Patients

Mathieu Simonin, Loïc Vasseur, Etienne Lengline, Ludovic Lhermitte, Aurelie Cabannes-Hamy, Marie Balsat, Aline Schmidt, Marie Emilie Dourthe, Aurore Touzart, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Isabelle Arnoux, Virginie Gandemer, Françoise Huguet, Stephane Ducassou, Véronique Lhéritier, Yves Chalandon, Norbert Ifrah, Herve Dombret, Elizabeth A. Macintyre, Arnaud Petit, Philippe Rousselot, Jerome Lambert, André Baruchel, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 142 (Supplement 1): 844.
https://doi.org/10.1182/blood-2023-179298
Published: 2023
Journal Articles

Chromothripsis and Genomic Complexity As Pejorative Prognostic Markers in Pediatric and Adult T-ALL

Estelle Balducci, Mathieu Simonin, Nicolas Duployez, Thomas Steimlé, Marie-Emilie Dourthe, Patrick Villarese, Stéphane Ducassou, Isabelle Arnoux, Jean-Michel Cayuela, Marie Balsat, Lucien Courtois, Guillaume P Andrieu, Aurore Touzart, Françoise Huguet, Arnaud Petit, Norbert Ifrah, Hervé Dombret, André Baruchel, Claude Preudhomme, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 142 (Supplement 1): 2980.
https://doi.org/10.1182/blood-2023-185831
Published: 2023
Journal Articles

Tyrosine Kinase Inhibitors with Intensive Chemotherapy in AML with t(9;22)(q34.1;q11.2)/ BCR::ABL1 : Time to Reconsider Prognostic Risk? a Study from the Dataml Registry

Camille Gondran, Pierre-Yves Dumas, Audrey Bidet, Emilie Bérard, Suzanne Tavitian, Thibaut Leguay, Françoise Huguet, Isabelle Luquet, Émilie Klein, Audrey Sarry, Anne-Charlotte De Grande, Eric Delabesse, Édouard Forcade, Cécile Borel, Arnaud Pigneux, Christian Recher, Laetitia Largeaud, Sarah Bertoli
Journal: Blood
Blood (2023) 142 (Supplement 1): 1473.
https://doi.org/10.1182/blood-2023-180817
Published: 2023
Journal Articles

Oncogenetic-Driven Targeted Therapy for Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia : A French ALL-Target Observatory Report

Aurelie Cabannes-Hamy, Lucien Courtois, Marie Balsat, Mathieu Simonin, Françoise Huguet, Martine Escoffre-Barbe, Florence Pasquier, Caroline Bonmati, Pascal Turlure, Thomas Cluzeau, Delphine Lebon, Eve Gehlkopf, Eolia Brissot, Justine Decroocq, Patrice Chevallier, Sylvain Chantepie, Victoria Cacheux, Sebastien Maury, Safia Chebrek, Thibaut Leguay, Melody Fort, Natacha Mauz, Mathlide Lamarque, Hunault-Berger Mathilde, Stefan Wickenhauser, Jamilé Frayfer, Anne Banos, Emmanuelle Tavernier, Denis Caillot, Anne Marie Ronchetti, Celine Berthon, Etienne Lengline, Véronique Lhéritier, Hervé Dombret, Ambroise Marçais, Antoine Pinton, Guillaume P Andrieu, Nicolas Boissel, Ludovic Lhermitte, Vahid Asnafi, Philippe Rousselot
Journal: Blood
Blood (2023) 142 (Supplement 1): 518.
https://doi.org/10.1182/blood-2023-179192
Published: 2023
Journal Articles

Exploring the Heterogeneity of Response to Blinatumomab in High-Risk Philadelphia-Negative B-Cell Precursor Acute Lymphoblastic Leukemia: An Analysis from the QUEST Sub-Study of the Graall-2014/B Trial

Nicolas Boissel, Francoise Huguet, Thibaut Leguay, Mathilde Hunault, Rathana KIM, Yosr Hicheri, Marie Passet, Patrice Chevallier, Marie Balsat, Sebastien Maury, Anne Thiebaut, Florence Van Obbergh, Thomas Cluzeau, Martine Escoffre Barbe, Nicole Straetmans, Johanna Konopacki, Amine Belhabri, Alban Villate, Florence Pasquier, Didier Bouscary, Thorsten Braun, Sabine Blum, Victoria Cacheux, Caroline Bonmati, Sebastian Wittnebel, Véronique Lhéritier, Norbert Ifrah, Carlos Graux, Yves Chalandon, Emmanuelle Clappier, Herve Dombret
Journal: Blood
Blood (2023) 142 (Supplement 1): 4349.
https://doi.org/10.1182/blood-2023-177847
Published: 2023
Journal Articles

T rial of Imatinib after Ponatinib Induction (TIPI) in the Front-Line Treatment of Chronic Phase (CP) Chronic Myeloid Leukemia (CML) Setting. Report of the First Therapeutic Sequence

Franck E. Nicolini, Aude Charbonnier, Martine Escoffre-Barbe, Eric Jourdan, Gabrielle Roth-Guepin, Marc G. Berger, Shanti Amé, Marion Simonet, Hyacinthe A. Johnson-Ansah, Viviane Dubruille, Amandine Charbonnier, Philippe Rousselot, Corentin Orvain, Bertrand Joly, Jean-Christophe Ianotto, Emilie Cayssials, Mathieu Meunier, Anne Parry, Valerie Coiteux, Laurence Legros, Hacene Zerazhi, Gabriel Etienne, Philippe Quittet, Ollivier Legrand, Amelie Penot, Lydia Roy, Ludovic Fouillet, Stéphane Morisset, Isabelle Tigaud, Romaine Mayet, Gwenaëlle Garin, Jérôme Guitton, Stéphanie Dulucq, Françoise Huguet
Journal: Blood
Blood (2023) 142 (Supplement 1): 445.
https://doi.org/10.1182/blood-2023-181571
Published: 2023
Journal Articles

Prognostic value and oncogenic landscape of TP53 alterations in adult and pediatric T-ALL

Clinical Trials & Observations
Mathieu Simonin, Guillaume P. Andrieu, Rudy Birsen, Marie Balsat, Guillaume Hypolite, Lucien Courtois, Carlos Graux, Nathalie Grardel, Jean-Michel Cayuela, Françoise Huguet, Yves Chalandon, Yannick Le Bris, Elizabeth Macintyre, Virginie Gandemer, Arnaud Petit, Philippe Rousselot, André Baruchel, Didier Bouscary, Olivier Hermine, Nicolas Boissel, Vahid Asnafi
Journal: Blood
Blood (2023) 141 (11): 1353–1358.
https://doi.org/10.1182/blood.2022017755
Published: 2023
Includes: Supplemental data