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Ewa Lech-Marańda
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Journal Articles

Safety and Early Efficacy of Obinutuzumab in Combination with Chemotherapy in Treatment Naive Patients with Follicular Lymphoma - Report of Polish Lymphoma Research Group (PLRG)

Ewa Paszkiewicz-Kozik, Iwona Hus, Monika Palka, Malgorzata Debowska, Agnieszka Konska, Martyna Kotarska, Agata Tyczynska, Monika Joks, Maja Twardosz, Agnieszka Giza, Ewa Wasik-Szczepanek, Elzbieta Kalicinska, Anna Wisniewska, Marta Morawska, Joanna Romejko-Jarosinska, Barbara Lewicka, Lukasz Targonski, Michal Osowiecki, Lidia Poplawska, Marcin Szymanski, Kamila Kruczkowska-Taranowicz, Joanna Drozd-Sokolowska, Ryszard Swoboda, Katarzyna Domanska-Czyz, Beata Ostrowska, Monika Swierkowska, Anna Paulina Dabrowska-Iwanicka, Agnieszka Druzd-Sitek, Robert Konecki, Anna Borawska, Monika Dlugosz-Danecka, Ewa Lech-Marańda, Jan Walewski
Journal: Blood
Blood (2021) 138 (Supplement 1): 4525.
DOI: https://doi.org/10.1182/blood-2021-145534
Published: 2021
Journal Articles

Favorable Outcomes for Patients Treated with U2 with Co-Morbidities or Concomitant Medications: A Retrospective Analysis of Unity-CLL Phase 3 Trial

Javier Pinilla Ibarz, Wojciech Jurczak, Suman Kambhampati, Ewa Lech Maranda, Tomasz Wróbel, Jeff P. Sharman, Syed F. Zafar, Marc Hoffmann, Scott F. Huntington, Ryan Jacobs, Osnat Bairey, Chris Rowland, Hari P. Miskin, Peter Sportelli, Michael S. Weiss, Owen A. O'Connor, Ian W. Flinn
Journal: Blood
Blood (2021) 138 (Supplement 1): 3748.
DOI: https://doi.org/10.1182/blood-2021-151292
Published: 2021
Journal Articles

Subgroup Analysis: Efficacy and Safety of Panobinostat in Combination with SC Bortezomib and Oral Dexamethasone in Multiple Myeloma Patients with Lenalidomide-Refractory Disease

Joshua Richter, Jacob P. Laubach, Steve Stricker, Fredrik H. Schjesvold, David Cohan, Anna Sureda, Ewa Lech-Marańda, Meral Beksac, Vania Hungria, Meletios A. Dimopoulos, Ajai Chari, Paul G. Richardson, Philippe Moreau
Journal: Blood
Blood (2021) 138 (Supplement 1): 3759.
DOI: https://doi.org/10.1182/blood-2021-153694
Published: 2021
Journal Articles

CLI120-001 Phase Ib Study of RVU120(SEL120) in Patients with AML and High Risk MDS: Updated Safety/Efficacy Results from Initial Dose Escalation

Camille Abboud, Sr., Gautam Borthakur, Scott R. Solomon, Howard A. Burris, Sr., Terrence Bradley, JAN Maciej Zaucha, Sr., Ewa Lech-Marańda, Krzysztof Brzozka, Tomasz Rzymski, Peter Littlewood, Elie Mouhayar, Setareh Shamsili, Noemi Angelosanto
Journal: Blood
Blood (2021) 138 (Supplement 1): 3418.
DOI: https://doi.org/10.1182/blood-2021-151030
Published: 2021
Journal Articles

Safety and Efficacy of Cusatuzumab in Combination with Venetoclax and Azacitidine (CVA) in Patients with Previously Untreated Acute Myeloid Leukemia (AML) Who Are Not Eligible for Intensive Chemotherapy; An Open-Label, Multicenter, Phase 1b Study

Gail J. Roboz, Thomas Pabst, Ahmed Aribi, Joseph M. Brandwein, Hartmut Döhner, Walter Fiedler, Domenica Gandini, Michelle Geddes, Jing-Zhou Hou, Angela J. Howes, Anna Hultberg, Eric Huselton, Julie Jacobs, Colleen Kane, Ewa Lech-Marańda, Marieke Louwers, Kerri Nottage, Uwe Platzbecker, Raajit Rampal, Mariya Salman, Priya Shah, Don Stevens, Monic Stuart, Marion Subklewe, Anne Sumbul, Eunice S. Wang, Agnieszka Wierzbowska, Bin Yao, Karen Yee, Hagop Kantarjian, Gautam Borthakur
Journal: Blood
Blood (2021) 138 (Supplement 1): 369.
DOI: https://doi.org/10.1182/blood-2021-150371
Published: 2021
Journal Articles

Pirtobrutinib, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated Mantle Cell Lymphoma: Updated Results from the Phase 1/2 BRUIN Study

Michael Wang, Nirav N. Shah, Alvaro J. Alencar, James N. Gerson, Manish R. Patel, Bita Fakhri, Wojciech Jurczak, Xuan Ni Tan, Katharine Lewis, Timothy S. Fenske, Catherine C. Coombs, Ian W. Flinn, David John Lewis, Steven Le Gouill, M. Lia Palomba, Jennifer A. Woyach, John M. Pagel, Nicole Lamanna, Jonathon B. Cohen, Minal A. Barve, Paolo Ghia, Toby A. Eyre, Pier Luigi Luigi Zinzani, Chaitra S. Ujjani, Youngil Koh, Koji Izutsu, Ewa Lech-Marańda, Constantine S. Tam, Suchitra Sundaram, Ming Yin, Binoj Nair, Minna Balbas, Donald Tsai, Anthony R. Mato, Chan Yoon Cheah
Journal: Blood
Blood (2021) 138 (Supplement 1): 381.
DOI: https://doi.org/10.1182/blood-2021-149138
Published: 2021
Journal Articles

Pirtobrutinib, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated CLL/SLL: Updated Results from the Phase 1/2 BRUIN Study

Anthony R. Mato, John M. Pagel, Catherine C. Coombs, Nirav N. Shah, Nicole Lamanna, Tahla Munir, Ewa Lech-Marańda, Toby A. Eyre, Jennifer A. Woyach, William G. Wierda, Chan Yoon Cheah, Jonathon B. Cohen, Lindsey E. Roeker, Manish R. Patel, Bita Fakhri, Minal A. Barve, Constantine S. Tam, David John Lewis, James N. Gerson, Alvaro J. Alencar, Chaitra S. Ujjani, Ian W. Flinn, Suchitra Sundaram, Shuo Ma, Deepa Jagadeesh, Joanna M Rhodes, Justin Taylor, Omar Abdel-Wahab, Paolo Ghia, Stephen J. Schuster, Denise Wang, Binoj Nair, Edward Zhu, Donald Tsai, Matthew S. Davids, Jennifer R. Brown, Wojciech Jurczak
Journal: Blood
Blood (2021) 138 (Supplement 1): 391.
DOI: https://doi.org/10.1182/blood-2021-147599
Published: 2021
Journal Articles

Robust Overall Survival and Sustained Efficacy Outcomes during Long Term Exposure to Momelotinib in JAK Inhibitor Naïve and Previously JAK Inhibitor Treated Intermediate/High Risk Myelofibrosis Patients

Srdan Verstovsek, MD PhD, Miklos Egyed, MD PhD, Ewa Lech-Marańda, MD PhD, Tomasz Sacha, MDPhD, Viviane Dubruille, MD, Stephen T. Oh, MD, Doroteya Todorieva-Todorova, MD, Francesco Passamonti, MD, Blanca Xicoy, MD, Björn Andréasson, MD PhD, Daniel El Fassi, MD, Claire Harrison, DM, FRCP, FRCPath, Donal P. McLornan, MRCP, PhD FRCPath, Mary Frances Frances McMullin, MDFRCPath,FRCP, Christof Scheid, MD, MArianne Tang Severinsen, MD PhD, Mark M Kowalski, MD PhD, Gregg Smith, PhD, Ruben Mesa, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 51–52.
DOI: https://doi.org/10.1182/blood-2020-135872
Published: 2020
Journal Articles

LOXO-305, A Next Generation, Highly Selective, Non-Covalent BTK Inhibitor in Previously Treated CLL/SLL: Results from the Phase 1/2 BRUIN Study

Anthony R. Mato, MD, John M. Pagel, MDPhD, Catherine C. Coombs, MD, Nirav N. Shah, MD, Nicole Lamanna, MD, Ewa Lech-Marańda, MD PhD, Toby A. Eyre, Jennifer A. Woyach, MD, William G. Wierda, MD PhD, Chan Yoon Cheah, MBBS, Lindsey E Roeker, MD, Manish R. Patel, MD, Bita Fakhri, MDMPH, Minal Barve, MD, Constantine S. Tam, MBBS, David John Lewis, MD, James N. Gerson, MD, Alvaro J. Alencar, MD, Justin Taylor, MD, Omar Abdel-Wahab, MD, Paolo Ghia, MD PhD, Stephen J. Schuster, MD, Jessica Chen, MS, Binoj Nair, PhD, Donald Tsai, MD PhD, Nora C. Ku, MD, Matthew S. Davids, MD, Jennifer R Brown, MD PhD, Wojciech Jurczak, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–37.
DOI: https://doi.org/10.1182/blood-2020-134970
Published: 2020
Journal Articles

Umbralisib, the Once Daily Dual Inhibitor of PI3Kδ and Casein Kinase-1ε Demonstrates Clinical Activity in Patients with Relapsed or Refractory Indolent Non-Hodgkin Lymphoma: Results from the Phase 2 Global Unity-NHL Trial

Pier Luigi Zinzani, MD, Felipe Samaniego, MD, Wojciech Jurczak, MD PhD, Nilanjan Ghosh, MD PhD, Enrico Derenzini, MD PhD, James A Reeves, MD, Wanda Knopinska-Posluszny, MD PhD, Chan Yoon Cheah, MBBS, Tycel J. Phillips, MD, Ewa Lech-Marańda, MD PhD, Bruce D. Cheson, MD, Paolo F Caimi, MD, Sebastian Grosicki, MD PhD, Lori A. Leslie, MD, Julio C. Chavez, MD, Gustavo A. Fonseca, MD, Sunil Babu, Daniel J. Hodson, MDPhD, Spencer H. Shao, MD, John M. Burke, MD, Jeff P Sharman, MD, Jennie Y. Law, MD, John M. Pagel, MDPhD, Owen A. O'Connor, MD PhD, Hari P. Miskin, MSc, Peter Sportelli, BS, Michael S. Weiss, Nathan H Fowler, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
DOI: https://doi.org/10.1182/blood-2020-134851
Published: 2020
Journal Articles

Final Analysis of the International Double-Blind Randomized Phase III Study of Lenalidomide Maintenance in Elderly Patients with DLBCL in Response after R-CHOP, the Remarc Study from Lysa

Catherine Thieblemont, MD PhD, Maria Gomes da Silva, MD, Olivier Casasnovas, MD, Hervé Ghesquieres, MD PhD, Gandhi Laurent Damaj, MD PhD, Judith Trotman, FRACP, Pierre Feugier, MD PhD, Corinne Haioun, MDPhD, Richard Greil, MD, Dolores Caballero, MD PhD, Armando Lopez-Guillermo, Sebastian Grosicki, MD PhD, Koen Van Eygen, MD, Sylvia Snauwaert, MD, Ewa Lech-Marańda, MD PhD, Sonja Heibl, MD, John Catalano, MBBS, FRACP, FRCPA, Amos Cohen, MD, Anne Cairoli, MD, Philippe Gaulard, MD PhD, Franck Morschhauser, MD PhD, Herve Tilly, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
DOI: https://doi.org/10.1182/blood-2020-136511
Published: 2020
Journal Articles

Efficacy and Safety of the Panobinostat-Bortezomib-Dexamethasone Combination in Relapsed or Relapsed/Refractory Multiple Myeloma: Results from the Randomized Panorama 3 Study

Jacob P. Laubach, MD, Fredrik Schjesvold, MDPhD, Mário Mariz, Meletios A Dimopoulos, Ewa Lech-Marańda, MD PhD, Ivan Spicka, MD PhD, Vania T. M. Hungria, MD PhD, Tatiana Shelekhova, Andre Abdo, MD, Lutz Jacobasch, Chantana Polprasert, MD, Roman Hajek, MD PhD, Arpad Illes, MD, Tomasz Wróbel, MD PhD, Anna Sureda Balari, MD PhD, Meral Beksac, MD, Iara Goncalves, Joan Bladé Creixenti, S. Vincent Rajkumar, MD, Ajai Chari, MD, Sagar Lonial, MD FACP, Andrew Spencer, Pierre Maison-Blanche, Philippe Moreau, MD, Paul G. Richardson, MD, Jesus F. San-Miguel, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 4–6.
DOI: https://doi.org/10.1182/blood-2020-140697
Published: 2020
Journal Articles

PIM Kinase Inhibition Decreases the Proangiogenic Properties of Multiple Myeloma Cells and Affects the Metabolic State of the Vascular Endothelium

Filip Garbicz, MD, Anna Szumera-Ciećkiewicz, MD PhD, Joanna Barankiewicz, MD, Dorota Komar, PhD, Michał Pawlak, PhD, Sonia Dębek, MSc, Aleksandra Matrejek, MSc, Thorsten Stuehmer, PhD, Aleksander Salomon-Perzynski, MD, Agata Malenda, MD PhD, Krzysztof Brzózka, PhD, Tomasz Rzymski, PhD, Andrea Massimiliano Tomirotti, PhD, Ewa Lech-Marańda, MD PhD, Monika Prochorec-Sobieszek, MD PhD, Maciej Szydlowski, PhD, Przemyslaw Juszczynski, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 16–17.
DOI: https://doi.org/10.1182/blood-2020-134979
Published: 2020
Journal Articles

Brentuximab Vedotin with Chemotherapy for Patients with Previously Untreated, Stage III/IV Classical Hodgkin Lymphoma: 5-Year Update of the ECHELON-1 Study

David J. Straus, MD, Monika Dlugosz-Danecka, MD PhD, Joseph M. Connors, MD, Árpád Illés, MD PhD, Marco Picardi, MD, Ewa Lech-Marańda, MD PhD, Tatyana Feldman, Piotr Smolewski, MD PhD, Kerry J. Savage, MDMSc, Nancy L. Bartlett, MD, Jan Walewski, MD, Radhakrishnan Ramchandren, MD, Pier Luigi Zinzani, MD, Martin Hutchings, MD PhD, Javier Munoz, MD, Won Seog Kim, MD PhD, Ranjana Advani, MD, Stephen M. Ansell, MD PhD, Anas Younes, Andrea Gallamini, Rachael Liu, PhD, Meredith Little, MPH, Keenan Fenton, Michelle A. Fanale, MD, John A. Radford, MD FMedSci
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–28.
DOI: https://doi.org/10.1182/blood-2020-137089
Published: 2020
Journal Articles

Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study

Clinical Trials & Observations
David J. Straus, Monika Długosz-Danecka, Sergey Alekseev, Árpád Illés, Marco Picardi, Ewa Lech-Maranda, Tatyana Feldman, Piotr Smolewski, Kerry J. Savage, Nancy L. Bartlett, Jan Walewski, Radhakrishnan Ramchandren, Pier Luigi Zinzani, Martin Hutchings, Joseph M. Connors, John Radford, Javier Munoz, Won Seog Kim, Ranjana Advani, Stephen M. Ansell, Anas Younes, Harry Miao, Rachael Liu, Keenan Fenton, Andres Forero-Torres, Andrea Gallamini
Journal: Blood
Blood (2020) 135 (10): 735–742.
DOI: https://doi.org/10.1182/blood.2019003127
Published: 2020
Includes: Supplemental data
Journal Articles

High Activity of Cladribine (2-CdA) Combined with Low-Dose Cytarabine in Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome after Azacitidine Failure

Kamil Wisniewski, Krzysztof Madry, Sebastian Grosicki, MD PhD, Piotr Małecki, Bartosz Pula, Marzena Watek, Ewa Lech-Maranda, MD PhD, Joanna Gora Tybor, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1360.
DOI: https://doi.org/10.1182/blood-2019-123843
Published: 2019
Journal Articles

Characteristics and Outcomes of Patients with Lymphoma Who Developed Therapy-Related Acute Myeloid Leukemia or Myelodysplastic Syndrome - a Retrospective Analysis of the Polish Adult Leukemia Group

Aleksandra Golos, MD PhD, Krzysztof Mądry, MD PhD, Karol Lis, Marta Sobas, MD, Agnieszka Ożańska, Magdalena Czemerska, Dorota Hawrylecka, Agnieszka Stelmach-Gołdyś, Karolina Chromik, Bartosz Pula, Ewa Lech-Maranda, MD PhD, Joanna Gora Tybor, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 5422.
DOI: https://doi.org/10.1182/blood-2019-125711
Published: 2019
Journal Articles

Brentuximab Vedotin with Chemotherapy for Stage 3/4 Classical Hodgkin Lymphoma (cHL): 4-Year Update of the Echelon-1 Study

Nancy L. Bartlett, MD, David J. Straus, MD, Monika Dlugosz-Danecka, MD PhD, Sergey Alekseev, PhD, Arpad Illes, MD, Ewa Lech-Maranda, MD PhD, Tatyana A. Feldman, MD, Piotr Smolewski, MD PhD, Kerry J Savage, BSc, MD MSc, Jan Walewski, MD PhD, Radhakrishnan Ramchandren, MD, Pier Luigi Zinzani, MD PhD, Martin Hutchings, MD PhD, Joseph M. Connors, MD, John Radford, Javier Munoz, MD MS, FACP, Won-Seog Kim, MD PhD, Ranjana H Advani, MD, Stephen M Ansell, MD PhD, Anas Younes, MD, Andrea Gallamini, MD, Harry Miao, MD, Rachael Liu, PhD, Keenan Fenton, Andres Forero-Torres, MD, Marco Picardi, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4026.
DOI: https://doi.org/10.1182/blood-2019-124116
Published: 2019
Journal Articles

Long-Term Evaluation of Efficacy and Safety of Ofatumumab Added to Fludarabine & Cyclophosphamide in Subjects with Relapsed Chronic Lymphocytic Leukemia: Final Analysis of Complement 2 Trial

Sebastian Grosicki, MD PhD, Ewa Lech-Maranda, MD PhD, K Govind Babu, MD DM, Justyna Rybka, MD PhD, Elena Litvinskaya, PhD, Javier Loscertales, MD, Irina Kryachok, Prof., PhD, Janusz Kłoczko, Prof., PhD, Grygoriy Rekhtman, MD, Wojciech Homenda, MD PhD, Jerzy Blonski, MD PhD, Tommaso Stefanelli, Ghislaine Vincent, Hiya Banerjee, Tadeusz Robak, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3151.
DOI: https://doi.org/10.1182/blood-2018-99-112139
Published: 2018
Journal Articles

Brentuximab Vedotin Alone and in Combination with Bendamustine As Salvage Therapy for Primary Refractory or Relapsed Hodgkin Lymphoma: Multicentre Experience of the Polish Lymphoma Research Group (PLRG)

Anna Czyz, MD PhD, Anna Lojko-Dankowska, Monika Joks, MD, Mieczyslaw Komarnicki, MD PhD, Monika Dlugosz-Danecka, MD PhD, Wojciech Jurczak, Justyna Rybka, MD PhD, Tomasz Wrobel, MD PhD, Ewa Paszkiewicz, Jan Walewski, MD, Dorota Hawrylecka, Joanna Drozd-Sokolowska, MD PhD, Edyta Subocz, Szymanska Agata, Magdalena Witkowska, Piotr Smolewski, MD PhD, Agnieszka Kolkowska, Ewa Lech Maranda, Wanda Knopinska-Posluszny, Sebastian Giebel, Jan Zaucha, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5375.
DOI: https://doi.org/10.1182/blood-2018-99-116610
Published: 2018