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Journal Articles

Assessing CAR-T Cell Product Quality: The Crucial Role of Metabolic and Persistence Analysis after Antigen Stimulation

Beatriz Guijarro-Albaladejo, Belén Sierro, Virginia Escamilla Gómez, Paola Hernández-Díaz, María de la Rosa-Garrido, Inmaculada Carrasco Brocal, Jose Antonio Bejarano Garcia, Patricia Alcalde Mellado, Alfonso Rodriguez Gil, Maribel Lara-Chica, José Antonio Pérez-Simón, Estefania Garcia-Guerrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 2096.
https://doi.org/10.1182/blood-2024-204757
Published: 2024
Journal Articles

Role of Antiapoptotic Protein Mcl1 in Graft-Versus-Host Disease

Jose Antonio Bejarano Garcia, Melanie Nufer, Maria Jose Palacios Barea, Beatriz Guijarro-Albaladejo, Inmaculada Carrasco Brocal, Belén Sierro, Estefania Garcia-Guerrero, Maribel Lara Chica, Teresa Caballero, Alfonso Rodríguez-Gil, Jose Antonio Pérez-Simón
Journal: Blood
Blood (2024) 144 (Supplement 1): 3395.
https://doi.org/10.1182/blood-2024-200823
Published: 2024
Journal Articles

Innovative Bone Marrow CAR-T Cell Manufacturing for AML: Enhancing Viability and Tumor Migration

Jose Antonio Bejarano Garcia, Daniel Primo, Maria Jose Palacios Barea, Belén Sierro, Beatriz Guijarro-Albaladejo, Xian Weng, Miranda Omenaca, Estefania Garcia-Guerrero, Joan Ballesteros, Jose Antonio Pérez-Simón
Journal: Blood
Blood (2024) 144 (Supplement 1): 3478.
https://doi.org/10.1182/blood-2024-201457
Published: 2024
Journal Articles

Validation of GMP Lentiviral Vector Production for CAR T-Cell Therapy in the Spanish Public Health System: Development of New QC Required By Aemps (Spanish FDA)

Maribel Lara Chica, María De La Rosa-Garrido, Blanca Arribas-Arribas, Miguel-Ángel Montiel-Aguilera, Raquel Muñoz-García, María Bermejo-González, Esteban Márquez-Pérez, Belén Sierro, Paola Hernández-Díaz, Beatriz Guijarro-Albaladejo, Inmaculada Carrasco Brocal, Virginia Escamilla Gómez, José Antonio Pérez-Simón, Gloria Carmona, Estefania Garcia-Guerrero
Journal: Blood
Blood (2024) 144 (Supplement 1): 7257.
https://doi.org/10.1182/blood-2024-207219
Published: 2024
Journal Articles

New Optimized Academic Anti-BCMA CAR (CARTemis-1): How Does the Manufacturing Process Impact CAR-T Cell Features?

Belén Sierro-Martínez, Virginia Escamilla Gomez, Laura Perez-Ortega, Beatriz Guijarro-Albaladejo, Paola Hernández-Díaz, María de la Rosa-Garrido, Maribel Lara-Chica, Juan Luis Reguera, Luzalba Sanoja Flores, Blanca Arribas-Arribas, Miguel-Ángel Montiel-Aguilera, Gloria Carmona, Maria-Jose Robles, Teresa Caballero, Javier Briones, Hermann Einsele, Michael Hudecek, Jose A. Pérez-Simón, Estefania Garcia-Guerrero
Journal: Blood
Blood (2023) 142 (Supplement 1): 6866.
https://doi.org/10.1182/blood-2023-186095
Published: 2023
Journal Articles

Detection, Monitoring and Cell Kinetics of Circulating CAR-T Cells in B-Cell Malignancies

Belén Sierro, Clara Beatriz Garcia-Calderon, Luzalba Sanoja-Flores, Victoria Ruiz-Maldonado, Javier Delgado Serrano, Agueda Molinos-Quintana, Juan Luis Reguera, Beatriz Guijarro-Albaladejo, Marta Reinoso-Segura, Estefania Garcia-Guerrero, Jose A. Perez-Simon, Teresa Caballero
Journal: Blood
Blood (2022) 140 (Supplement 1): 7550–7551.
https://doi.org/10.1182/blood-2022-163106
Published: 2022
Journal Articles

Post-Transplant Cyclophosphamide after HLA Identical Compared to Haploidentical Donor Transplant in Acute Myeloid Leukemia: A Study on Behalf of Geth-TC

Rebeca Bailen, Maria Jesus Pascual-Cascon, Manuel Guerreiro, Lucía López Corral, Anabelle Chinea, Arancha Bermúdez, Antonia Sampol, Inmaculada Heras, Estefanía García-Torres, Melissa Torres, Jose J. Rifon Roca, Beatriz Herruzo, Jaime Sanz, Marta Fonseca, Pilar Herrera, Mercedes Colorado, Leyre Bento, Oriana López-Godino, Carmen Martin Calvo, Gillen Oarbeascoa, Jose L. Diez-Martin, Mi Kwon
Journal: Blood
Blood (2021) 138 (Supplement 1): 3913.
https://doi.org/10.1182/blood-2021-150835
Published: 2021
Journal Articles

ATRA Augments BCMA Expression on Myeloma Cells and Enhances Recognition By BCMA-CAR T-Cells

Estefania Garcia-Guerrero, PhD, Luis Gerardo Rodríguez-Lobato, Sophia Danhof, MD, Belén Sierro-Martínez, Ralph Goetz, Markus Sauer, Jose A. Perez-Simon, MD PhD, Hermann Einsele, MD, Michael Hudecek, MD, Sabrina Prommersbe
Journal: Blood
Blood (2020) 136 (Supplement 1): 13–14.
https://doi.org/10.1182/blood-2020-142572
Published: 2020
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation for T Cell Lymphomas: Improved Results Overtime

Silvana Novelli, PhDMD, Leyre Bento, Irene García-Cadenas, Laura Prieto, MD, Lucía López Corral, MD, Gonzalo Gutierrez Garcia, MD, Rafael Hernani, Ariadna Pérez Martínez, Jorge Sierra, MD, Carlos Solano, MD PhD, Mariana Bastos-Oreiro, MD PhD, Nieves Dorado, MD, Nancy Rodríguez-Torres, MD, Guillermo Rodríguez, MD, Jose Luis Piñana Sanchez, Juan Montoro Gómez, Pilar Herrera Puente, Alejandro Luna, MD, Isabel Sanchez Ortega, MD PhD, Carmen Martin Calvo, Oriana López-Godino, MD PhD, Inmaculada Heras, MD PhD, Joud Zanabili, MD, María Del Pilar Palomo Moraleda, MD, Rocio Parody, Jose Maria Moraleda, Lucrecia Yáñez, MD PhD, Antonio Gutiérrez, Teresa Zudaire, MD, Raul Cordoba, MD PhD, Rosario Varela, Christelle M Ferra, Joaquin Martinez-Lopez, MD PhD, Estefania García-Torres, MD, Dolores Caballero, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3325.
https://doi.org/10.1182/blood-2019-126507
Published: 2019
Journal Articles

Pre-Clinical Trial to Evaluate the Efficacy of Delayed Administration of Ixazomib in the Prophylaxis of Chronic Graft-Versus-Host Disease

Teresa Ramos, PhD, Alfonso Rodríguez-Gil, PhD, Melanie Nufer, María Victoria Barbado, PhD, Estefania Garcia Guerrero, PhD, Rocio Caracuel-García, Tehcnician, Teresa Caballero-Velázquez, MD PhD, José A. Pérez-Simón, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4521.
https://doi.org/10.1182/blood-2018-99-118098
Published: 2018
Journal Articles

Thrombopoietin Receptor Agonists for Severe Thrombocytopenia after Allogeneic Stem Cell Transplantation: Experience of a Multicenter Study from the Grupo Español De Trasplante Hematopoyético (GETH)

Leyre Bento, MD, Jose Maria Bastida, MDPhD, Irene García-Cadenas, Estefania García-Torres, MD, Daniel Rivera, MD, Anna Bosch, MD, Carlos de Miguel, MD, María Esther Martínez-Muñoz, MD, Francesc Fernández-Avilés, MD, Elisa Roldan, MD, Anabelle Chinea, MD, Lucrecia Yáñez, MD PhD, Teresa Zudaire, MD, Carlos Pinho-Vaz, MD, Ildefonso Espigado, MD PhD, Javier Lopez Jimenez, MD PhD, David Valcárcel, MD, Rafael F Duarte, MDPhDFRCP, Rafael Cabrera, MD PhD, Antonio Gutiérrez, MD PhD, Carlos Solano, MD PhD, Antonia Sampol, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 200.
https://doi.org/10.1182/blood-2018-200
Published: 2018
Journal Articles

Identification and Isolation of Tumor-Specific Cytotoxic T Lymphocytes in Acute Myeloid Leukemia Patients through the Identification of T-Cells Capable to Establish Stable Interactions with Leukemic Cells

Estefania Garcia-Guerrero, Luis I. Sanchez-Abarca, PhD, Esther Domingo, PhD, Teresa Ramos, PhD, Jose Antonio Bejarano-García, Jose A Gonzalez-Campos, MD, Teresa Caballero-Velázquez, MD PhD, José A. Pérez-Simón, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3336.
https://doi.org/10.1182/blood-2018-99-118118
Published: 2018
Journal Articles

Efficacy of Autologous Stem Cell Transplantation in First Complete Remission in Patients with Peripheral T-Cell Lymphoma: A Multicenter Geltamo/FIL Study

Miriam López-Parra, MD, Monica Bellei, MSc, PhD, Alessandro Rambaldi, MD Prof, Silvana Novelli, Carlos Panizo, MD PhD, Maurizio Martelli, Ivan Dlouhy, Mariana Bastos, MD, Antonio Gutierrez, MD PhD, Juan Manuel Sancho, MD PhD, María José Ramírez Sánchez, José M Moraleda, MD, Estrella Carrillo-Cruz, MD, Ana Isabel Jiménez Ubieto, Isidro Jarque, Umberto Vitolo, MD, Natalia de las Heras, Reyes Arranz, Javier Lopez Jimenez, Carlos Montalban, MD PhD, Maria Pascual, Paolo Corradini, MD, Sabela Bobillo, MD, Estefania García-Torres, Michele Spina, Giuseppe Rossi, MD, Martina Manni, PhD, Dolores Caballero, MD PhD, Massimo Federico, MD, Alejandro Martín, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2008.
https://doi.org/10.1182/blood.V130.Suppl_1.2008.2008
Published: 2017
Journal Articles

CCR6, IL7R, FAS and Madcam-1 Single Nucleotide Polymorphisms Are Associated with Higher Incidence of Infections in Allogeneic Stem-Cell Transplant from a Related Donor after a Reduced Intensity Conditioning Regimen: A Multicenter Experience

Nerea Arratibel, MD, María Garcia-Alvarez, Oriana López-Godino, Estefania Garcia Guerrero, Oscar Ferré, Eduardo Rodríguez-Arbolí, MD, Albert Esquirol, Cristina Castilla, Rodrigo Martino, MD PhD, Luis Antonio Corchete Sanchez, MSc, Inmaculada Heras, José A. Pérez-Simón, Estefania Pérez-López, MD, Monica Cabrero, MD, Sara Alonso, MD, Ana A. Martín, MD, Ana Balanzategui, Lourdes Vázquez, MD, Ramón García-Sanz, MD, Luis Marin, Marcos González, MD, Lucia Lopez Corral, Dolores Caballero, MD PhD, Miguel Alcoceba
Journal: Blood
Blood (2017) 130 (Supplement 1): 3208.
https://doi.org/10.1182/blood.V130.Suppl_1.3208.3208
Published: 2017
Journal Articles

Upregulation of CD38 Expression on Multiple Myeloma Cells By the HDAC Inhibitor Ricolinostat Augments the Efficacy of Daratumumab

Estefania Garcia-Guerrero, Sophia Danhof, Martin Schreder, MD, José A. Pérez-Simón, Hermann Einsele, Michael Hudecek
Journal: Blood
Blood (2017) 130 (Supplement 1): 1803.
https://doi.org/10.1182/blood.V130.Suppl_1.1803.1803
Published: 2017
Journal Articles

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab

Clinical Trials & Observations
Estefanía García-Guerrero, Tea Gogishvili, Sophia Danhof, Martin Schreder, Celine Pallaud, Jose Antonio Pérez-Simón, Hermann Einsele, Michael Hudecek
Journal: Blood
Blood (2017) 129 (25): 3386–3388.
https://doi.org/10.1182/blood-2017-03-770776
Published: 2017
Includes: Supplemental data
Journal Articles

Panobinostat Induces Upregulation of CD38 and Augments the Anti-Myeloma Efficacy of Daratumumab in Pre-Clinical Models

Estefania Garcia-Guerrero, Tea Gogishvili, PhD, Sophia Danhof, MD, Martin Schreder, MD, Celine Pallaud, PhD, Thomas Lehmann, PhD, Hermann Einsele, MD, Michael Hudecek, MD
Journal: Blood
Blood (2016) 128 (22): 4481.
https://doi.org/10.1182/blood.V128.22.4481.4481
Published: 2016
Journal Articles

Molecular Dynamics As a Computational Tool to Study the Immune Reactivity: Identification of Conformational Changes in the Major Histocompatibility Complex

Estefania Garcia Guerrero, Jose Antonio Pérez Simon, Luis Ignacio Sánchez Abarca, Irene Diaz Moreno, Miguel Angel De la rosa, Antonio Diaz Quintana
Journal: Blood
Blood (2014) 124 (21): 2735.
https://doi.org/10.1182/blood.V124.21.2735.2735
Published: 2014
Journal Articles

Molecular Dynamics As a Computational Tool To Analyze Lymphocyte Alloreactivity In Hematopoietic Transplant Recipients

Estefania Garcia Guerrero, Irene Diaz Moreno, Miguel Angel De la rosa, Jose Antonio Pérez Simón, MD, PhD, Antonio Diaz Quintana
Journal: Blood
Blood (2013) 122 (21): 1049.
https://doi.org/10.1182/blood.V122.21.1049.1049
Published: 2013
Journal Articles

Myelomatous Plasma Cells Display An Intermediate Gene Expression Pattern Between a Normal Plasma Cell and a Memory B Cell

Alicia Baez, Jose Ignacio Piruat, Ph.D, Teresa Caballero-Velazquez, María Victoria Barbado, Ph.D, Isabel Alvarez-Laderas, Africa Millan-Ucles, Mayte Medrano, Estefania Garcia-Guerrero, Luis Ignacio Sanchez-Abarca, Ph.D., Ildefonso Espigado, Jose Antonio Perez-Simón, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1892.
https://doi.org/10.1182/blood.V122.21.1892.1892
Published: 2013