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Journal Articles

Role of Allogeneic Transplantation In Chronic Myelomonocytic Leukemia: An International Collaborative Analysis

Marie Robin, Liesbeth C. de Wreede, Eric Padron, Katerina Bakunina, Pierre Fenaux, Linda Koster, Aziz Nazha, Dietrich W. Beelen, Raajit K. Rampal, Katja Sockel, Rami S. Komrokji, Nico Gagelmann, Dirk-Jan Eikema, Aleksandar Radujkovic, Jürgen Finke, Victoria Potter, Sally Killick, Faezeh Legrand-Izadifar, Eric Solary, Angus Broom, Guillermo Garcia-Manero, Vittorio Rizzoli, Patrick Hayden, Mrinal M Patnaik, Francesco Onida, Ibrahim Yakoub-Agha, Raphaël A. Itzykson
Journal: Blood
Blood blood.2021015173.
DOI: https://doi.org/10.1182/blood.2021015173
Published: 2022
Includes: Supplemental data
Journal Articles

Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation

Xiaona You, Fabao Liu, Moritz Binder, Alexis Vedder, Terra Lasho, Zhi Wen, Xin Gao, Evan Flietner, Adhithi Rajagopalan, Yun Zhou, Christy Finke, Abhishek Mangaonkar, Ruiqi Liao, Guangyao Kong, Erik A. Ranheim, Nathalie Droin, Anthony M. Hunter, Sergey Nikolaev, Maria Balasis, Omar Abdel-Wahab, Ross L. Levine, Britta Will, Kalyan Vara Ganesh Nadiminti, David Yang, Klaus Geissler, Eric Solary, Wei Xu, Eric Padron, Mrinal M. Patnaik, Jing Zhang
Journal: Blood
Blood (2022) 139 (7): 1066–1079.
DOI: https://doi.org/10.1182/blood.2021012519
Published: 2022
Includes: Supplemental data
Journal Articles

Inferring the dynamics of mutated hematopoietic stem and progenitor cells induced by IFNα in myeloproliferative neoplasms

Matthieu Mosca, Gurvan Hermange, Amandine Tisserand, Robert Noble, Christophe Marzac, Caroline Marty, Cécile Le Sueur, Hugo Campario, Gaëlle Vertenoeil, Mira El-Khoury, Cyril Catelain, Philippe Rameau, Cyril Gella, Julien Lenglet, Nicole Casadevall, Rémi Favier, Eric Solary, Bruno Cassinat, Jean-Jacques Kiladjian, Stefan N. Constantinescu, Florence Pasquier, Michael E. Hochberg, Hana Raslova, Jean-Luc Villeval, François Girodon, William Vainchenker, Paul-Henry Cournède, Isabelle Plo
Journal: Blood
Blood (2021) 138 (22): 2231–2243.
DOI: https://doi.org/10.1182/blood.2021010986
Published: 2021
Includes: Supplemental data
Journal Articles

SRSF2-P95Hdelays Myelofibrosis Development through Altered JAK/STAT Signaling in JAK2-V617F Megakaryocytes

Christophe Willekens, Lucie Laplane, Tracy Dagher, Camélia Benlabiod, Catherine Lacout, Philippe Rameau, Cyril Catelain, Alexia Alfaro, Valérie Edmond, Nicolas Signolle, Aymeric Silvin, Florent Ginhoux, Valentine Marchand, Nathalie Droin, Remco Hoogenboezem, Rebekka K. Schneider, Alexander V Penson, Omar Abdel-Wahab, Patrick Gonin, Caroline Marty, Isabelle Plo, Jean-Luc Villeval, Francoise Porteu, William Vainchenker, Eric Solary
Journal: Blood
Blood (2021) 138 (Supplement 1): 2544.
DOI: https://doi.org/10.1182/blood-2021-149757
Published: 2021
Journal Articles

Development of a Fast and Reproducible Assay for the Clinical Implementation of Epigenetic Biomarkers to Predict Decitabine Response in Patients with Chronic Myelomonocytic Leukemia

Masataka Taguchi, Maikel Anthonissen, Aristeidis G. Telonis, Qin Yang, Eric Solary, Valeria Santini, Maria E. Figueroa
Journal: Blood
Blood (2021) 138 (Supplement 1): 1515.
DOI: https://doi.org/10.1182/blood-2021-147855
Published: 2021
Journal Articles

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Margaux Sevin, Franck Debeurme, Lucie Laplane, Séverine Badel, Margot Morabito, Hanna L. Newman, Miguel Torres-Martin, Qin Yang, Bouchra Badaoui, Orianne Wagner-Ballon, Véronique Saada, Dorothée Sélimoglu-Buet, Laurence Kraus-Berthier, Sébastien Banquet, Alix Derreal, Pierre Fenaux, Raphael Itzykson, Thorsten Braun, Gabriel Etienne, Celine Berthon, Sylvain Thépot, Oliver Kepp, Guido Kroemer, Eric Padron, Maria E. Figueroa, Nathalie Droin, Eric Solary
Journal: Blood
Blood (2021) 137 (24): 3390–3402.
DOI: https://doi.org/10.1182/blood.2020008729
Published: 2021
Includes: Supplemental data
Journal Articles

Decitabine Versus Hydroxyurea for Advanced Proliferative CMML: Results of the Emsco Randomized Phase 3 Dacota Trial

Raphael Itzykson, MD PhD, Valeria Santini, Cendrine Chaffaut, Ades Lionel, Sylvain Thepot, MD, Aristoteles Giagounidis, Margot Morabito, Nathalie Droin, Michael Luebbert, Rosa Sapena, Stanislas Nimubona, MD, Jean E. Goasguen, MD PhD, Eric Wattel, MD PhD, Gina Zini, MDPhD, Jose Miguel Torregrosa Diaz, Ulrich Germing, Anna Maria Pelizzari, Sophie Park, MD PhD, Nadja Jaekel, Georgia Metzgeroth, Francesco Onida, MD, Robert Navarro, Andrea Patriarca, MD, Aspasia Stamatoulas Bastard, MD, Martin Puttrich, Sandra Mossuto, Eric Solary, MD PhD, Silke Gloaguen, Msc, Sylvie Chevret, MD PhD, Fatiha Chermat, Uwe Platzbecker, Pierre Fenaux, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 53–54.
DOI: https://doi.org/10.1182/blood-2020-138680
Published: 2020
Journal Articles

Eltrombopag in Chronic Myelomonocytic Leukemia (CMML) with Severe Thrombocytopenia: Final Results of a Multicenter Phase II Study

Florence Rabian, MD, Jérôme Lambert, Daniela Barbieri, Berengere Gruson, MD, Sylvain Thepot, MD, Thorsten Braun, MD PhD, Norbert Vey, MD, Jacques Delaunay, MD, Laurence Legros, PhD MD, Julie Lejeune, Anouk Walter-petrich, Rosa Sapena, Nathalie Droin, PhD, Fatiha Chermat, Francoise Porteu, Daniel Lusina, Lionel Ades, MDPhD, Eric Solary, MD PhD, Pierre Fenaux, MDPhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 15–16.
DOI: https://doi.org/10.1182/blood-2020-137469
Published: 2020
Journal Articles

Depletion of the Long Non-Coding RNA MALAT1 primes Chronic Myelomonocytic Leukemia (CMML) for Differentiation Therapy with All- Trans retinoic Acid (ATRA) through the Transcription Factor CREB

Maria E Balasis, Alexis Vedder, BS, Lei Sun, Ariel Quintana, PhD, Abhishek Dhawan, Hannah Newman, BS, Jane Merlevede, Kathy McGraw, PhD, Traci Kruer, PhD, Nana Ben-Crentsil, Jeffrey S Painter, BS, Nathalie Droin, PhD, Thomas Cluzeau, MD PhD, Christopher Letson, BS, Sheng Wei, MD, Rami S. Komrokji, MD, Hailing Zhang, MD, A. Robert MacLeod, PhD, Alan F. List, MD, Eric Solary, MD PhD, Pearlie K. Epling-Burnette, Eric Padron, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1692.
DOI: https://doi.org/10.1182/blood-2019-128573
Published: 2019
Journal Articles

Timing for Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) in Chronic Myelomonocytic Leukemia (CMML): A Joint Study from the International MDS/MPN Working Group and the Chronic Malignancies Working Party of the EBMT

Marie Robin, MD, Liesbeth C. de Wreede, PhD, Eric Padron, MD, Junfeng Wang, PhD, Sheree Hazelaar, Dietrich W. Beelen, Pierre Fenaux, MD PhD, Martin Bornhäuser, MD, Nicolaus Kroeger, MD, Aziz Nazha, MD, Aleksandar Radujkovic, MD, Raajit K. Rampal, MD PhD, Jürgen Finke, MD, Rami S. Komrokji, MD, Victoria Potter, MD PhD, Sally Killick, MD, Didier Blaise, MD PhD, Eric Solary, MD PhD, Angus Broom, Guillermo Garcia-Manero, MD, Vittorio Rizzoli, MD, Mrinal M Patnaik, MDMBBS, Francesco Onida, MD, Ibrahim Yakoub-Agha, MD PhD, Raphael Itzykson, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4581.
DOI: https://doi.org/10.1182/blood-2019-125077
Published: 2019
Journal Articles

Peripheral Blood Cell Sorting Strategies for Transcriptomic Analysis in Chronic Myelomonocytic Leukemia

Moritz Binder, MDMPH, Ryan Carr, MD PhD, Nathalie Droin, PhD, Abhishek A Mangaonkar, MBBS, Giacomo Coltro, MD, Luciana L Almada, PhD, David Marks, PhD, Kurt Berger, Terra Lasho, PhD, Naseema Gangat, MBBS, Christopher Pin, PhD, Martin Fernandez-Zapico, MD, Eric Solary, MD PhD, Mrinal M Patnaik, MDMBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 4232.
DOI: https://doi.org/10.1182/blood-2019-122187
Published: 2019
Journal Articles

Clonal Hematopoiesis in the Molecular Landscape of Therapy-Related Myeloid Neoplasms in Patients Previously Treated for Gynecologic and Breast Cancers

Sabine Khalife-Hachem, Khalil Saleh, MD, Florence Pasquier, MD PhD, Anthony Tarabay, Cyril Quivoron, Sophie Cotteret, Christophe Willekens, MD, Veronique Saada, Ines-Maria Vaz-Luis, Suzette Delaloge, Alexandra Leary, Hana Raslova, PhD, Filippo Rosselli, Olivier Caron, Iléana Antony-Debre, PhD, Eric Solary, MD PhD, Stephane de Botton, MD PhD, Christophe Marzac, MD, Jean-Baptiste Micol, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3722.
DOI: https://doi.org/10.1182/blood-2019-126872
Published: 2019
Journal Articles

Predicting the Long-Term Efficacy of Ifnα in JAK2 V617F and Calr -Mutated MPN Patients

Amandine Tisserand, Robert Noble, PhD, Matthieu Mosca, PhD, Christophe Marzac, MD, Gaelle Vertenoeil, MD, Hugo Campario, PharmD, Mira El-Khoury, PhD, Caroline Marty, PhD, Philippe Rameau, Nicole Casadevall, MD, Eric Solary, MD PhD, Florence Pasquier, MD PhD, Hana Raslova, PhD, Bruno Cassinat, PharmD, PhD, Stefan N Constantinescu, MD PhD, Jean-Jacques Kiladjian, MD PhD, Francois Girodon, MD PhD, Michael Hochberg, PhD, Villeval Jean-Luc, PhD, William Vainchenker, MD PhD, Isabelle Plo
Journal: Blood
Blood (2019) 134 (Supplement_1): 4196.
DOI: https://doi.org/10.1182/blood-2019-127903
Published: 2019
Journal Articles

The Absolute Count of Circulating, Classical, CD14 ++ /CD16 - Monocytes Is a Poor Prognosis Marker in Chronic Myelomonocytic Leukemia (CMML)

Matthieu Jestin, Sihem Tarfi, PharmD, Bouchra Badaoui, PharmD, Nicolas Freynet, PharmD, Ivan Sloma, PharmD,PhD, Margot Morabito, Sébastien Maury, MD PhD, Pierre Fenaux, MD PhD, Eric Solary, MD PhD, Dorothée Selimoglu-Buet, PhD, Orianne Wagner Ballon, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4242.
DOI: https://doi.org/10.1182/blood-2019-121794
Published: 2019
Journal Articles

Abnl Marro : An International Cooperative Trial for Patients with MDS/MPN Overlap Syndromes

Michael R. Savona, MD, Pierre Fenaux, MD PhD, Eric Padron, MD, Mrinal M Patnaik, MDMBBS, Uwe Platzbecker, MD, Adam Seegmiller, MD PhD, Raphael Itzykson, MD PhD, Guillermo F. Sanz, MD PhD, Valeria Santini, MD, Eric Solary, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4273.
DOI: https://doi.org/10.1182/blood-2019-130722
Published: 2019
Journal Articles

Familial predisposition to TP53/complex karyotype MDS and leukemia in DNA repair-deficient xeroderma pigmentosum

Alain Sarasin, Samuel Quentin, Nathalie Droin, Mourad Sahbatou, Véronique Saada, Nathalie Auger, Yannick Boursin, Philippe Dessen, Anna Raimbault, Vahid Asnafi, Jean-Luc Schmutz, Alain Taïeb, Carlos F. M. Menck, Filippo Rosselli, Laurianne Drieu La Rochelle, Caroline Robert, Flore Sicre de Fontbrune, Marie Sébert, Thierry Leblanc, Patricia Kannouche, Stéphane De Botton, Eric Solary, Jean Soulier
Journal: Blood
Blood (2019) 133 (25): 2718–2724.
DOI: https://doi.org/10.1182/blood-2019-01-895698
Published: 2019
Includes: Supplemental data
Journal Articles

Using Healthcare Claims Data to Analyze the Prevalence of Chronic Myeloid Leukemia in France: A Nationwide Population-Based Study

Stephanie Foulon, MD, Pascale Cony-Makhoul, MD PhD, Agnes Guerci-Bresler, MD PhD, Marc Delord, PhD, Eric Solary, MD PhD, Alain Monnereau, MD PhD, Julia Bonastre, PhD, Pascale Tubert Bitter, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3015.
DOI: https://doi.org/10.1182/blood-2018-99-111489
Published: 2018
Journal Articles

Disappearance of Slan-Positive Non-Classical Monocytes As a New Parameter for the Diagnosis of Chronic Myelomonocytic Leukemia with Associated Inflammatory State

Sihem Tarfi, PharmD, Bouchra Badaoui, PharmD, Nicolas Freynet, PharmD, Margot Morabito, Jeffie Lafosse, Andrea Toma, MD PhD, Pierre Fenaux, MD PhD, Eric Solary, MD PhD, Dorothée Selimoglu-Buet, PhD, Orianne Wagner Ballon, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4376.
DOI: https://doi.org/10.1182/blood-2018-99-116451
Published: 2018
Journal Articles

Differential Impact of Interferon Alpha on JAK2 V617F and Calr Mutated Hematopoietic Stem and Progenitor Cells in Classical MPN

Matthieu Mosca, PhDstudent, Lamia Lamrani, PhD, Christophe Marzac, MD, Amandine Tisserand, Valérie Edmond, PhD, Tracy Dagher, PhDstudent, Mira El-Khoury, PhD, Caroline Marty, PhD, Hugo Campario, PharmD, Nicole Casadevall, MD, Eric Solary, MD PhD, Hana Raslova, PhD, Bruno Cassinat, PharmD, PhD, Stefan N Constantinescu, MD, Jean-Jacques Kiladjian, MD PhD, Francois Girodon, MD PhD, Jean-Luc Villeval, PhD, William Vainchenker, MD PhD, Isabelle Plo, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4333.
DOI: https://doi.org/10.1182/blood-2018-99-114744
Published: 2018
Journal Articles

Indoleamine 2,3-Dioxygenase-1 Expressing Dendritic Cell Populations Are Associated with Tumor-Induced Immune Tolerance & Aggressive Disease Biology in Chronic Myelomonocytic Leukemia

Abhishek A. Mangaonkar, MD, Kaaren K. Reichard, MD, April Chiu, MD, Matthew T Howard, MD, Rebecca L King, MD, Ryan M. Carr, MD, PhD, Bonnie M Alver, Keith D. Robertson, Margot Cousin, PhD, Jose C Villasboas, Martin E. Fernandez-Zapico, MD, Terra L. Lasho, PhD, Naseema Gangat, MBBS, Aref Al-Kali, MD, Michelle A. Elliott, MD, William J. Hogan, MBBCh, Mark R. Litzow, MD, Animesh Pardanani, MBBS, PhD, Eric Solary, MD PhD, Ayalew Tefferi, MD, Mrinal M. Patnaik, MD MBBS
Journal: Blood
Blood (2018) 132 (Supplement 1): 4344.
DOI: https://doi.org/10.1182/blood-2018-99-113881
Published: 2018