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Elizabeth A. Raetz
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Journal Articles

Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome

Open Access
Changya Chen, Jason Xu, Jonathan H. Sussman, Tiffaney Vincent, Joseph S. Tumulty, Satoshi Yoshimura, Fatemeh Alikarami, Wenbao Yu, Yang-yang Ding, Chia-hui Chen, Elizabeth Y. Li, Austin Yang, Xiaohuan Qin, Shovik Bandyopadhyay, Jacqueline Peng, Petri Pölönen, Haley Newman, Brent L. Wood, Jianzhong Hu, Rawan Shraim, Andrew D. Hughes, Caroline Diorio, Lahari Uppuluri, Gongping Shi, Theresa Ryan, Tori Fuller, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Stanley B. Pounds, Charles G. Mullighan, David Frank, Jun J. Yang, Kathrin M. Bernt, David T. Teachey, Kai Tan
Journal: Blood
Blood (2025) 145 (23): 2685–2700.
https://doi.org/10.1182/blood.2024027270
Published: 2025
Includes: Supplemental data
Journal Articles

Daratumumab in pediatric relapsed/refractory acute lymphoblastic leukemia or lymphoblastic lymphoma: the DELPHINUS study

Available to Purchase
Clinical Trials & Observations
Teena Bhatla, Laura E. Hogan, David T. Teachey, Francisco Bautista, John Moppett, Pablo Velasco Puyó, Concetta Micalizzi, Claudia Rossig, Neerav Shukla, Gil Gilad, Franco Locatelli, André Baruchel, C. Michel Zwaan, Natalie S. Bezler, Alba Rubio-San-Simón, David C. Taussig, Elizabeth A. Raetz, Zhengwei J. Mao, Brent L. Wood, Diana Alvarez Arias, Maria Krevvata, Ivo Nnane, Nibedita Bandyopadhyay, Lorena Lopez Solano, Robyn M. Dennis, Robin Carson, Ajay Vora
Journal: Blood
Blood (2024) 144 (21): 2237–2247.
https://doi.org/10.1182/blood.2024024493
Published: 2024
Includes: Supplemental data
Journal Articles

Prognostic Impact of t(1;19) in Pediatric B-Cell Acute Lymphoblastic Leukemia (B-ALL) Patients Treated on Contemporary Children's Oncology Group (COG) Protocols

Free
Ashley Pinchinat, John A. Kairalla, Meenakshi Devidas, Andrew J. Carroll, Mary Shago, Anne Angiolillo, Michael J. Burke, Wanda L. Salzer, Naomi J. Winick, Mignon L. Loh, David T. Teachey, Elizabeth A. Raetz, Karen R Rabin, Rachel E. Rau, Sumit Gupta
Journal: Blood
Blood (2024) 144 (Supplement 1): 315.
https://doi.org/10.1182/blood-2024-198507
Published: 2024
Journal Articles

TCL1A Is Associated with Blinatumomab Response and Immune Activation in Pediatric B-ALL

Free
Andrew Hughes, Rawan Shraim, Lahari Uppuluri, Haley Newman, Gongping Shi, Julie Asare, Theresa Ryan, Elizabeth A. Raetz, James A. Whitlock, Maureen M. O'Brien, Deepa Bhojwani, Rachel E. Rau, Kara L. Davis, Stacy Cooper, Patrick Brown, Stephen P. Hunger, Mignon L. Loh, Laura E. Hogan, Stephan A. Grupp, Jun J. Yang, David T. Teachey, Caroline Diorio
Journal: Blood
Blood (2024) 144 (Supplement 1): 634.
https://doi.org/10.1182/blood-2024-203756
Published: 2024
Journal Articles

The Role of an Inflammatory Phenotype in Driving Clonal Evolution in B-Acute Lymphoblastic Leukemia

Free
Danielle Wolfe Cohen, Clemence Aldebert, Emily Duan, Sylwia Jasinski, Xiaotu Ma, Heather L. Mulder, John Easton, Jiyuan Hu, Laura E. Hogan, David T. Teachey, Elizabeth A. Raetz, Nikki Evensen, William L. Carroll
Journal: Blood
Blood (2024) 144 (Supplement 1): 633.
https://doi.org/10.1182/blood-2024-205379
Published: 2024
Journal Articles

Blinatumomab Added to Chemotherapy Improves Disease-Free Survival in Newly Diagnosed NCI Standard Risk Pediatric B-Acute Lymphoblastic Leukemia: Results from the Randomized Children's Oncology Group Study AALL1731

Free
Rachel E. Rau, Sumit Gupta, John A. Kairalla, Karen R Rabin, Anne Angiolillo, Cindy Wang, Andrew J. Carroll, Susan Conway, Meenakshi Devidas, Lia Gore, Ilan R. Kirsch, Holly R. Kubaney, Amanda M Li, Jennifer L. McNeer, Olga Militano, Yvonne Moyer, Maureen M. O'Brien, Maki Okada, Shalini C. Reshmi, Mary Shago, Elizabeth R. Wagner, Naomi J. Winick, Brent L. Wood, Faraz Zaman, Gerhard Zugmaier, Sue Zupanec, Stephen P. Hunger, David T. Teachey, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1.
https://doi.org/10.1182/blood-2024-207450
Published: 2024
Journal Articles

Interferon-Activated Gene Signatures Associate with Chemotherapy Resistance and Sensitivity to JAK-Inhibition in Refractory ETP-ALL

Free
Jason Xu, Jonathan Sussman, Austin Yang, Satoshi Yoshimura, Changya Chen, Omar Elghawy, Tiffaney Vincent, Caroline Diorio, Shovik Bandyopadyay, Jianzhong Hu, Alexander Lai Li, Gregory M. Chen, Chia-Hui Chen, Rawan Shraim, Haley Newman, Yang Ding, Elizabeth Li, Wenbao Yu, Anusha Thadi, Kyung Jin Ahn, Petri Pölönen, Abdelrahman Elsayed, David Frank, Elizabeth A. Raetz, Mignon L. Loh, Brent L. Wood, Stuart S. Winter, Kimberly P. Dunsmore, Meenakshi Devidas, Chunxu Qu, Stanley Pounds, Stephen P. Hunger, Charles G. Mullighan, Jun J. Yang, Kai Tan, David T. Teachey
Journal: Blood
Blood (2024) 144 (Supplement 1): 1464.
https://doi.org/10.1182/blood-2024-211090
Published: 2024
Journal Articles

Utility of a Second Interim Maintenance Phase to Improve Outcomes for Pediatric Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Free
Etan Orgel, Michael J. Burke, John A. Kairalla, Emily Hibbitts, Meenakshi Devidas, Michael J. Borowitz, Brent L. Wood, Nyla A. Heerema, Andrew J. Carroll, Kelly Maloney, Leonard A. Mattano, Anne Angiolillo, Eric C. Larsen, Wanda L. Salzer, David T. Teachey, Naomi J. Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Mignon L. Loh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2813.
https://doi.org/10.1182/blood-2024-194872
Published: 2024
Journal Articles

Examining Disparities By Race, Ethnicity, and Socioeconomic Factors in Children and Young Adults with Relapsed Acute Lymphoblastic Leukemia: A Report from the Children's Oncology Group

Free
John A Ligon, Deepa Bhojwani, Alice Dang, Lingyun Ji, Susan R Rheingold, Xinxin Xu, Meenakshi Devidas, John A. Kairalla, Mary Shago, Nyla A. Heerema, Andrew J. Carroll, Michael J. Borowitz, Brent L. Wood, Naomi J. Winick, William L. Carroll, Stephen P. Hunger, Elizabeth A. Raetz, Mignon L. Loh, Sumit Gupta, Lena E Winestone
Journal: Blood
Blood (2024) 144 (Supplement 1): 2797.
https://doi.org/10.1182/blood-2024-193893
Published: 2024
Journal Articles

Additional Induction Intrathecal Cytarabine for Patients with CNS2 Disease at Diagnosis Is Not Beneficial for Patients with B-ALL Treated on Children's Oncology Group Protocols AALL0932 and AALL1131

Free
Cathy A. Lee-Miller, John A. Kairalla, Emily Hibbitts, Naomi J. Winick, Anne Angiolillo, Reuven J. Schore, Wanda L. Salzer, Michael J. Burke, Mignon L. Loh, Elizabeth A. Raetz, Stephen P. Hunger, Meenakshi Devidas, David T. Teachey, Sumit Gupta, Jennifer L. McNeer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4195.
https://doi.org/10.1182/blood-2024-203456
Published: 2024
Journal Articles

Germ line genetic NBN variation and predisposition to B-cell acute lymphoblastic leukemia in children

Free
Carolin S. Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A. Raetz, Meenakshi Devidas, Gang Wu, Kim E. Nichols, Hiroto Inaba, Ching-Hon Pui, Sima Jeha, Bruce M. Camitta, Eric Larsen, Stephen P. Hunger, Mignon L. Loh, Jun J. Yang
Journal: Blood
Blood (2024) 143 (22): 2270–2283.
https://doi.org/10.1182/blood.2023023336
Published: 2024
Includes: Supplemental data
Journal Articles

MRD at the end of induction and EFS in T-cell lymphoblastic lymphoma: Children’s Oncology Group trial AALL1231

Free
CME Clinical Trials & Observations Brief Report
Robert J. Hayashi, Michelle L. Hermiston, Brent L. Wood, David T. Teachey, Meenakshi Devidas, Zhiguo Chen, Robert D. Annett, Barbara L. Asselin, Keith August, Steve Cho, Kimberly P. Dunsmore, Jason Lawrence Freedman, Paul J. Galardy, Paul Harker-Murray, Terzah M. Horton, Alok Jaju, Allison Lam, Yoav H. Messinger, Rodney R. Miles, Maki Okada, Samir Patel, Eric S. Schafer, Tal Schechter, Kristin A. Shimano, Neelam Singh, Amii Steele, Maria L. Sulis, Sarah L. Vargas, Stuart S. Winter, Charlotte Wood, Patrick A. Zweidler-McKay, Mignon L. Loh, Stephen P. Hunger, Elizabeth A. Raetz, Catherine M. Bollard, Carl E. Allen
Journal: Blood
Blood (2024) 143 (20): 2053–2058.
https://doi.org/10.1182/blood.2023021184
Published: 2024
Includes: Supplemental data
Journal Articles

Prognostic significance of ETP phenotype and minimal residual disease in T-ALL: a Children’s Oncology Group study

Free
Clinical Trials & Observations
Brent L. Wood, Meenakshi Devidas, Ryan J. Summers, Zhiguo Chen, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Naomi J. Winick, Michael J. Borowitz, William L. Carroll, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Kimberly P. Dunsmore, David T. Teachey, Stuart S. Winter
Journal: Blood
Blood (2023) 142 (24): 2069–2078.
https://doi.org/10.1182/blood.2023020678
Published: 2023
Includes: Supplemental data
Journal Articles

The Role of over-Expressed β Globin in Driving Relapsed B - Cell Acute Lymphoblastic Leukemia (B-ALL)

Free
Jessica Krugman, Sylwia Jasinski, Elizabeth A. Raetz, Nikki Evensen, William L. Carroll
Journal: Blood
Blood (2023) 142 (Supplement 1): 6072.
https://doi.org/10.1182/blood-2023-180976
Published: 2023
Journal Articles

Heritable Variation in Lymphocyte-Related Traits and Risk of Down Syndrome Acute Lymphoblastic Leukemia: A Mendelian Randomization Study

Free
Yunqi Li, Melissa A. Richard, Linda Kachuri, Yao Yu, Ching-Ju Ruu Hsu, Tracie C. Rosser, Elizabeth J. Leslie, Meenakshi Devidas, Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Neetha Paul Eduthan, Matthew D. Galbraith, Joaquin Espinosa, Jun J. Yang, Stephanie L. Sherman, Chad D. Huff, Karen R. Rabin, Philip J. Lupo, Adam J. de Smith
Journal: Blood
Blood (2023) 142 (Supplement 1): 4198.
https://doi.org/10.1182/blood-2023-188434
Published: 2023
Journal Articles

Efficacy and Safety of Recombinant Erwinia Asparaginase (JZP458) in Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL): Complete Follow-up of the Children's Oncology Group (COG) AALL1931 Study

Free
Luke Maese, Mignon L. Loh, Mi Rim Choi, Tong Lin, Etsuko Aoki, Shirali Agarwal, Vijayalakshmi Chandrasekaran, Yali Liang, Suzette Girgis, Cuiping Chen, Robert Iannone, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 142 (Supplement 1): 1498.
https://doi.org/10.1182/blood-2023-172577
Published: 2023
Journal Articles

Impact of Treatment with Inotuzumab Ozogamicin before or after Chimeric Antigen Receptor T-Cell Therapy in Children with Relapsed/Refractory Acute Lymphoblastic Leukemia

Free
Susan R Rheingold, Lingyun Ji, Lia Gore, Xinxin Xu, Deepa Bhojwani, Nirali N. Shah, Elizabeth A. Raetz, Mignon L. Loh, Maureen M. O'Brien
Journal: Blood
Blood (2023) 142 (Supplement 1): 2876.
https://doi.org/10.1182/blood-2023-183103
Published: 2023
Journal Articles

Immunogenicity of Recombinant Erwinia asparaginase (JZP458) for Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Free
Luke Maese, Mignon L. Loh, Mi Rim Choi, Yali Liang, Etsuko Aoki, Shane Roller, Tong Lin, Shirali Agarwal, Vijayalakshmi Chandrasekaran, Robert Iannone, Lewis B. Silverman, Elizabeth A. Raetz, Rachel E. Rau
Journal: Blood
Blood (2023) 142 (Supplement 1): 5908.
https://doi.org/10.1182/blood-2023-179533
Published: 2023
Journal Articles

Patients with Down Syndrome and High-Risk B-Acute Lymphoblastic Leukemia Demonstrate Improved Outcomes on a Modified Chemotherapy Regimen: A Report from Children's Oncology Group Study AALL1131

Free
Vilmarie Rodriguez, Meenakshi Devidas, Zhiguo (Bruce) Chen, Andrew J Carroll, Nyla A. Heerema, Michael J. Borowitz, Brent L. Wood, William L. Carroll, Naomi J Winick, Elizabeth A. Raetz, Mignon L. Loh, Michael J. Burke, Wanda L. Salzer, Stephen P. Hunger, Karen R. Rabin
Journal: Blood
Blood (2023) 142 (Supplement 1): 824.
https://doi.org/10.1182/blood-2023-185368
Published: 2023
Journal Articles

Risk-Adjusted Therapies Yield Equivalent Outcomes for Adolescents and Young Adults (AYAs) Treated for Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) on Children's Oncology Group (COG) Studies AALL0434 and AALL1231

Free
Susan I. Colace, Meenakshi Devidas, Zhiguo (Bruce) Chen, Robert J. Hayashi, Brent L. Wood, Natia Esiashvili, Samir Patel, Andrew J Carroll, Nyla A. Heerema, Barbara Asselin, Karen R. Rabin, Patrick A. Zweidler-McKay, Elizabeth A. Raetz, Mignon L. Loh, Naomi J. Winick, William L. Carroll, David T. Teachey, Stuart S. Winter, Kimberly P. Dunsmore
Journal: Blood
Blood (2023) 142 (Supplement 1): 517.
https://doi.org/10.1182/blood-2023-190141
Published: 2023