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Elisabeth Paietta
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Journal Articles

DNA polymerase theta protects leukemia cells from metabolic-induced DNA damage

Umeshkumar Vekariya, Monika Maria Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Anna-Mariya Kukuyan, Katherine Sullivan-Reed, Paulina Podszywalow-Bartnicka, Kumaraswamy Naidu Chitrala, Jessica Atkins, Malgorzata Drzewiecka, Wanjuan Feng, Joe Chan, Srinivas Chatla, Konstantin Golovine, Jaroslav Jelinek, Tomasz Sliwinski, Jayashri Ghosh, Ksenia Matlawska-Wasowska, Gurushankar Chandramouly, Reza Nejati, Mariusz A Wasik, Stephen Sykes, Katarzyna Piwocka, Emir Hadzijusufovic, Peter Valent, Richard T Pomerantz, George Morton, Wayne Childers, Huaqing Zhao, Elisabeth Paietta, Ross L. Levine, Martin S. Tallman, Hugo Fernandez, Mark R Litzow, Gaorav Gupta, Jean-Yves Masson, Tomasz Skorski
Journal: Blood
Blood blood.2022018428.
DOI: https://doi.org/10.1182/blood.2022018428
Published: 2022
Includes: Supplemental data
Journal Articles

Consolidation Therapy with Blinatumomab Improves Overall Survival in Newly Diagnosed Adult Patients with B-Lineage Acute Lymphoblastic Leukemia in Measurable Residual Disease Negative Remission: Results from the ECOG-ACRIN E1910 Randomized Phase III National Cooperative Clinical Trials Network Trial

Mark R. Litzow, Zhuoxin Sun, Elisabeth Paietta, Ryan J. Mattison, Hillard M Lazarus, Jacob M. Rowe, Daniel A. Arber, Charles G. Mullighan, Cheryl L Willman, Yanming Zhang, Matthew Wieduwilt, Michaela Liedtke, Julie Bergeron, Keith W. Pratz, Shira Dinner, Noelle V. Frey, Steven D. Gore, Bhavana Bhatnagar, Ehab L. Atallah, Geoffrey L. Uy, Deepa Jeyakumar, Tara L. Lin, Richard F. Little, Selina M. Luger, Martin S. Tallman
Journal: Blood
Blood (2022) 140 (Supplement 2): LBA-1.
DOI: https://doi.org/10.1182/blood-2022-171751
Published: 2022
Journal Articles

Chromatin Accessibility Landscapes of B-Cell Acute Lymphoblastic Leukemia Identify Extensive Epigenomic Reprogramming and Heterogeneity Among Subtypes

Kelly R. Barnett, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic
Journal: Blood
Blood (2022) 140 (Supplement 1): 5907–5908.
DOI: https://doi.org/10.1182/blood-2022-166528
Published: 2022
Journal Articles

A Phosphatase Membrane-Shuttle Enables Feedback Control of B-Cell Signaling

Jaewoong Lee, Kohei Kume, Mark E. Robinson, Ruifeng Sun, Ning Ma, Zhengshan Chen, Gang Xiao, Kadriye Nehir Cosgun, Lai N. Chan, Etienne Leveille, Lars Klemm, Vivasvan Vykunta, Brian Shy, Huimin Geng, Selina M. Luger, Mark R. Litzow, Alexander Marson, Elisabeth Paietta, Nagarajan Vaidehi, Eric Meffre, Markus Müschen
Journal: Blood
Blood (2022) 140 (Supplement 1): 1698–1699.
DOI: https://doi.org/10.1182/blood-2022-170324
Published: 2022
Journal Articles

Characteristics and Prognostic Effects of DNMT3A Co-Mutations

Alireza Torabi, Todd A. Alonzo, Megan Othus, Robert B. Gerbing, Yi-Cheng Wang, Rhonda E. Ries, Jerald P. Radich, Frederick R. Appelbaum, Kristin O'Dwyer, Harry P. Erba, Martin S. Tallman, Mark R. Litzow, Ehab L. Atallah, Selina M. Luger, Anders E. Kolb, Omar Abdel-Wahab, Derek Stirewalt, Ross L. Levine, Elisabeth Paietta, Soheil Meshinchi
Journal: Blood
Blood (2022) 140 (Supplement 1): 745–747.
DOI: https://doi.org/10.1182/blood-2022-162526
Published: 2022
Journal Articles

DNA Polymerase Theta Protects Leukemia Cells from Metabolic-Induced DNA Damage

Umeshkumar M Vekariya, Katherine Sullivan-Reed, Monika Toma, Margaret Nieborowska-Skorska, Bac Viet Le, Marie-Christine Caron, Anna-Mariya Kukuyan, Paulina Podszywalow-Bartnicka, Kumaraswamy Chitrala, Jessica Atkins, Malgorzata Drzewiecka, Wanjuan Feng, Joe Chan, Konstantin Golovine, Jaroslav Jelinek, Tomasz Sliwinski, Jayashri Ghosh, Ksenia Maslawska-Wasowska, Reza Nejati, Mariusz A Wasik, Stephen M. Sykes, Katarzyna Piwocka, Emir Hadzijusufovic, Peter Valent, Richard Pomerantz, George Morton, Wayne Childers, Huaqing Zhao, Elisabeth Paietta, Ross L. Levine, Martin S. Tallman, Hugo F Fernandez, Mark R. Litzow, Gaorav P Gupta, Jean-Yves Masson, Tomasz Skorski
Journal: Blood
Blood (2022) 140 (Supplement 1): 2972–2974.
DOI: https://doi.org/10.1182/blood-2022-156458
Published: 2022
Journal Articles

PAX5 Epigenetically Orchestrates CD58 Transcription and Modulates Blinatumomab Response in Acute Lymphoblastic Leukemia

Yizhen Li, Takaya Moriyama, Satoshi Yoshimura, Xuijie Zhao, Zhenhua LI, Xu Yang, Jacob A Steele, Shondra Miller, Elisabeth Paietta, Marina Konopleva, Jiyang Yu, Hiroto Inaba, Raul C Ribeiro, Ching-Hon Pui, Jun J. Yang
Journal: Blood
Blood (2022) 140 (Supplement 1): 1041–1042.
DOI: https://doi.org/10.1182/blood-2022-156746
Published: 2022
Journal Articles

Epigenetic Fine Mapping and Functional Dissection of Inherited Non-Coding Variation Impacting the Pharmacogenomics of Acute Lymphoblastic Leukemia Treatment

Kashi Raj Bhattarai, Kelly R. Barnett, Robert J. Mobley, Daniel C. Ferguson, Jonathan D. Diedrich, Brennan P. Bergeron, Wenjian Yang, Kristine R. Crews, Wendy Stock, Elisabeth Paietta, Steven M. Kornblau, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Cheng Cheng, Mary V. Relling, William E. Evans, Jun J.J. Yang, Daniel Savic
Journal: Blood
Blood (2022) 140 (Supplement 1): 3027–3028.
DOI: https://doi.org/10.1182/blood-2022-167419
Published: 2022
Journal Articles

Maximal Tolerated Dose Determined for Venetoclax in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory Ph-Negative T-Cell or B-Cell Acute Lymphoblastic Leukemia: Results of Phase 1 Portion of ECOG-ACRIN EA9152

Neil Palmisiano, Ju-Whei Lee, David F. Claxton, Elisabeth Paietta, Hassan B. Alkhateeb, Jae H Park, Nikolai Podoltsev, Ehab L. Atallah, Dale G Schaar, Shira Dinner, Jonathan Webster, Selina M. Luger, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 3407.
DOI: https://doi.org/10.1182/blood-2021-153621
Published: 2021
Journal Articles

Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study

Yishai Ofran, Zhuoxin Sun, Jacob M. Rowe, David F. Claxton, Martin S. Tallman, Daniel A. Arber, Ari Melnick, Ross L. Levine, Elisabeth Paietta, John E. Godwin, Hillard M Lazarus, Selina M. Luger, James M. Foran, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (Supplement 1): 413.
DOI: https://doi.org/10.1182/blood-2021-149356
Published: 2021
Journal Articles

Molecular classification improves risk assessment in adult BCR-ABL1– negative B-ALL

Elisabeth Paietta, Kathryn G. Roberts, Victoria Wang, Zhaohui Gu, Georgina A. N. Buck, Deqing Pei, Cheng Cheng, Ross L. Levine, Omar Abdel-Wahab, Zhongshan Cheng, Gang Wu, Chunxu Qu, Lei Shi, Stanley Pounds, Cheryl L. Willman, Richard Harvey, Janis Racevskis, Jan Barinka, Yanming Zhang, Gordon W. Dewald, Rhett P. Ketterling, David Alejos, Hillard M. Lazarus, Selina M. Luger, Letizia Foroni, Bela Patel, Adele K. Fielding, Ari Melnick, David I. Marks, Anthony V. Moorman, Peter H. Wiernik, Jacob M. Rowe, Martin S. Tallman, Anthony H. Goldstone, Charles G. Mullighan, Mark R. Litzow
Journal: Blood
Blood (2021) 138 (11): 948–958.
DOI: https://doi.org/10.1182/blood.2020010144
Published: 2021
Includes: Supplemental data
Journal Articles

Early Assessment of Treatment Response in Acute Myeloid Leukemia Using FLT PET/CT Imaging: A Trial of the ECOG-ACRIN Cancer Research Group (EAI141)

Robert Jeraj, PhD, Fenghai Duan, PhD, Ryan J. Mattison, MD, Lale Kostakoglu, MD MPH, Daniel A. Arber, MD, Elisabeth Paietta, PhD, Justin Romanoff, AM, Jennifer Holter-Chakrabarty, MD, Charles Arnold, MD, Stephen A. Strickland, MD, Jennifer Whisenant, PhD, Barry Alan Siegel, MD, Geoffrey L Uy, MD, Kebede H. Begna, MD, Gregory Wiseman, MD, Aric C. Hall, MD, Scott Perlman, MD, Mark Litzow, MD, David Mankoff, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
DOI: https://doi.org/10.1182/blood-2020-136721
Published: 2020
Journal Articles

Maintenance Decitabine (DAC) Improves Disease-Free (DFS) and Overall Survival (OS) after Intensive Therapy for Acute Myeloid Leukemia (AML) in Older Adults, Particularly in FLT3-ITD-Negative Patients: ECOG-ACRIN (E-A) E2906 Randomized Study

James M. Foran, MD, Zhuoxin Sun, David F. Claxton, MD, Hillard M Lazarus, MD, Daniel A. Arber, MD, Jacob M. Rowe, MB, BS, Elisabeth Paietta, PhD, Janis Racevskis, PhD, Jessica K. Altman, Selina M. Luger, MD FRCPC, Aref Al-Kali, MD, Hong Zheng, MD PhD, Keith W. Pratz, MD, Edward R. Broun, MD, Bayard L Powell, MD, Kristen Marie O'Dwyer, MD, John E. Godwin, MD, Yishai Ofran, MD, Mark Litzow, MD, Martin S. Tallman, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 115.
DOI: https://doi.org/10.1182/blood-2019-129876
Published: 2019
Journal Articles

A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403

Clinical Trials & Observations
Wendy Stock, Selina M. Luger, Anjali S. Advani, Jun Yin, Richard C. Harvey, Charles G. Mullighan, Cheryl L. Willman, Noreen Fulton, Kristina M. Laumann, Greg Malnassy, Elisabeth Paietta, Edy Parker, Susan Geyer, Krzysztof Mrózek, Clara D. Bloomfield, Ben Sanford, Guido Marcucci, Michaela Liedtke, David F. Claxton, Matthew C. Foster, Jeffrey A. Bogart, John C. Grecula, Frederick R. Appelbaum, Harry Erba, Mark R. Litzow, Martin S. Tallman, Richard M. Stone, Richard A. Larson
Journal: Blood
Blood (2019) 133 (14): 1548–1559.
DOI: https://doi.org/10.1182/blood-2018-10-881961
Published: 2019
Journal Articles

FLT3-ITD Mutations Are Prevalent and Significantly Impact Outcome after Intensive Therapy in Elderly Adults with Acute Myeloid Leukemia (AML): Analysis of the North American Intergroup E2906 Phase III Trial in Patients Age ≥60 Years

James M. Foran, MD, Zhuoxin Sun, PhD, Elisabeth Paietta, PhD, Janis Racevskis, PhD, David F. Claxton, MD, Hillard M Lazarus, MD, Daniel A. Arber, MD, Jacob M. Rowe, MD, John Godwin, MD, Yanming Zhang, MD, Martin S. Tallman, MD, Mark R. Litzow, MD, Keith W. Pratz, MD, Selina Luger, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3995.
DOI: https://doi.org/10.1182/blood-2018-99-117838
Published: 2018
Journal Articles

Minimal Residual Disease (MRD) at Time of Complete Remission Is Commonly Detected in Acute Myeloid Leukemia (AML) Patients Age ≥60 Years and Significantly Impacts Outcome Based on Post-Remission Treatment Strategies: Prospective Analysis of ECOG-ACRIN (E-A) E2906 Phase III Trial

James M. Foran, MD, Zhuoxin Sun, PhD, Elisabeth Paietta, PhD, Janis Racevskis, PhD, David F. Claxton, MD, Hillard M Lazarus, MD, Daniel A. Arber, MD, Jacob M. Rowe, MD, Jessica K. Altman, MD, Aref Al-Kali, MD, Hong Zheng, MDPhD, Keith W. Pratz, MD, Edward R. Broun, MD, Bayard L. Powell, MD, Kristen Marie O'Dwyer, MD, John Godwin, MD, Yanming Zhang, MD, Martin S. Tallman, MD, Selina Luger, MD, Mark R. Litzow, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 437.
DOI: https://doi.org/10.1182/blood-2018-99-113950
Published: 2018
Journal Articles

Consensus on MRD in AML?

Elisabeth Paietta
Journal: Blood
Blood (2018) 131 (12): 1265–1266.
DOI: https://doi.org/10.1182/blood-2018-01-828145
Published: 2018
Journal Articles

Prospective Study of Acute Myeloid Leukemia (AML) Clinical Epidemiology and Cytogenetic Risk Group in Older Adults in the ECOG-ACRIN E2906 Clinical Trial: The Acute Leukemia Epidemiology, Survival and Endpoints (ALESE) Study

James M. Foran, MD, Yanming Zhang, MD, Michael Heckman, MS, Selina Luger, MD FRCPC, Cassondra Hulshizer, BA, Emily Vargas, MPH, Mark R. Litzow, MD, Jessica K. Altman, MD, Keith Pratz, MD, Ryan Mattison, MD, David F. Claxton, Geoffrey L. Uy, MD, Harry P. Erba, MD PhD, Mohamad A. Cherry, MDMS, Edward R. Broun, MD, Bayard L. Powell, MD, Hillard M Lazarus, MD, Jacob M. Rowe, MD, Elisabeth Paietta, PhD, Richard F. Little, MDMPH, Jen Poynter, PhD, Martin S. Tallman, MD, James R. Cerhan, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2579.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.2579.2579
Published: 2017
Journal Articles

Genomic Landscapes in Elderly AML

Franck Rapaport, PhD, Timour Baslan, PhD, Ling Wang, MS, Caroline Sheridan, Tak Lee, Todd Hricik, Marc Robert de Massy, Leonid Telis, Yaseswini Neelamraju, Juan Medina, Larry D Cripe, MD, Martin S. Tallman, MD, Scott Lowe, PhD, Zhuoxin Sun, PhD, Yanming Zhang, MD, Donna S. Neuberg, ScD, Elisabeth Paietta, PhD, Ari Melnick, MD, Ross L. Levine, MD, Maria Kleppe, PhD, Francine E. Garrett-Bakelman, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 404.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.404.404
Published: 2017
Journal Articles

CD25 Enables Oncogenic BCR-Signaling and Represents a Therapeutic Target in B Cell Malignancies

Jaewoong Lee, PhD, Huimin Geng, PhD, Zhengshan Chen, MDPhD, Gang Xiao, PhD, Kadriye Nehir Nehir Cosgun, PhD, Francesca Zammarchi, PhD, Patrick Van Berkel, PhD, Ari Melnick, MD, Elisabeth Paietta, PhD, Markus Muschen, MDPhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3834.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3834.3834
Published: 2017