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Deborah M. Stephens
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Journal Articles

Subclonal evolution of CLL driver mutations is associated with relapse in ibrutinib and acalabrutinib treated patients

Gage S. Black, Xiaomeng Huang, Yi Qiao, Szabolcs Tarapcsak, Kerry A. Rogers, Shrilekha Misra, John C. Byrd, Gabor T. Marth, Deborah M. Stephens, Jennifer A. Woyach
Journal: Blood
Blood blood.2021015132.
DOI: https://doi.org/10.1182/blood.2021015132
Published: 2022
Includes: Supplemental data
Journal Articles

Phase 1 TRANSCEND CLL 004 study of lisocabtagene maraleucel in patients with relapsed/refractory CLL or SLL

Clinical Trials & Observations
Tanya Siddiqi, Jacob D. Soumerai, Kathleen A. Dorritie, Deborah M. Stephens, Peter A. Riedell, Jon Arnason, Thomas J. Kipps, Heidi H. Gillenwater, Lucy Gong, Lin Yang, Ken Ogasawara, Jerill Thorpe, William G. Wierda
Journal: Blood
Blood (2022) 139 (12): 1794–1806.
DOI: https://doi.org/10.1182/blood.2021011895
Published: 2022
Includes: Supplemental data
Journal Articles

Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions

Clinical Trials & Observations
Victor Manuel Orellana-Noia, Daniel R. Reed, Ashley Alesia McCook, Jeremy Michael Sen, Christian M. Barlow, Mary-Kate Malecek, Marcus Watkins, Brad S. Kahl, Michael A. Spinner, Ranjana Advani, Timothy J. Voorhees, Anson Snow, Natalie Sophia Grover, Amy Ayers, Jason Romancik, Yuxin Liu, Scott F. Huntington, Julio C. Chavez, Hayder Saeed, Aleksandr Lazaryan, Vikram Raghunathan, Stephen E. Spurgeon, Thomas A. Ollila, Christopher Del Prete, Adam Olszewski, Emily C. Ayers, Daniel J. Landsburg, Benjamin Echalier, Jun Lee, Manali Kamdar, Paolo F. Caimi, Timothy Fu, Jieqi Liu, Kevin A. David, Hanan Alharthy, Jennie Law, Reem Karmali, Harsh Shah, Deborah M. Stephens, Ajay Major, Alexandra E. Rojek, Sonali M. Smith, Amulya Yellala, Avyakta Kallam, Shazi Nakhoda, Nadia Khan, Mohammad Ahsan Sohail, Brian T. Hill, Odeth Barrett-Campbell, Frederick Lansigan, Jeffrey Switchenko, Jonathon Cohen, Craig A. Portell
Journal: Blood
Blood (2022) 139 (3): 413–423.
DOI: https://doi.org/10.1182/blood.2021012888
Published: 2022
Includes: Supplemental data
Journal Articles

Outcomes and Treatment Patterns in Patients with Aggressive B-Cell Lymphoma after Failure of Anti-CD19 CAR T-Cell Therapy

Joanna C. Zurko, Narendranath Epperla, Imran Nizamuddin, Pallawi Torka, Kevin A. David, Thomas A. Ollila, Brian T. Hess, Jonathon B. Cohen, Robert Ferdman, Jieqi Liu, Sayan Mullick Chowdhury, Kaitlyn O'Shea, Jason Romancik, Rahul Bhansali, Elyse Harris, Mckenzie Sorrell, Rebecca Masel, Lindsey Fitzgerald, Carlos Galvez, Shuo Ma, Jane N. Winter, Barbara Pro, Leo I. Gordon, Alexey V. Danilov, Deborah M. Stephens, Nirav N. Shah, Geoffrey Shouse, Vaishalee P. Kenkre, Stefan K. Barta, Reem Karmali
Journal: Blood
Blood (2021) 138 (Supplement 1): 884.
DOI: https://doi.org/10.1182/blood-2021-147433
Published: 2021
Journal Articles

Treatment Outcomes of Consolidative Radiation in Extranodal Early-Stage Diffuse Large B-Cell Lymphoma

Daniel A. Ermann, Victoria A. Vardell, Harsh Shah, Randa Tao, David K. Gaffney, Deborah M. Stephens, Boyu Hu
Journal: Blood
Blood (2021) 138 (Supplement 1): 49.
DOI: https://doi.org/10.1182/blood-2021-153197
Published: 2021
Journal Articles

Impact of Molecular Features of Diffuse Large B-Cell Lymphoma on Treatment Outcomes with Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy

Brian T. Hill, Caroline J Roth, Rachel Kositsky, Tushar Dave, Cassandra Love, Matthew McKinney, Ahmed Galal, Jadee L Neff, Agrima Mian, Ellen Kendall, Sarah L. Ondrejka, Matthew Chiaramonte, Govind Bhagat, Kenneth Ofori, Ran Reshef, Alexandra E. Kovach, Tarsheen Sethi, Emily F Mason, Shakthi Bhaskar, Olalekan O. Oluwole, Christopher Pallas, Nilanjan Ghosh, Robert Ferdman, George L. Chen, Francisco J. Hernandez-Ilizaliturri, Joanna C. Zurko, Ashley Cunningham, Nirav N. Shah, Boyu Hu, Deborah M. Stephens, Monalisa Ghosh, Neil Bailey, Krish Patel, John M. Pagel, Kavya Kannamma Kannan, Eric D. Hsi, Rakhee Vaidya, Andrew Ip, Andre H. Goy, Swetha Kambhampati, Robert S. Ohgami, Charalambos Andreadis, Elizabeth Thacker, Chrissie Rozzi, Clay Parker, Lanie Happ, Sandeep S. Dave
Journal: Blood
Blood (2021) 138 (Supplement 1): 165.
DOI: https://doi.org/10.1182/blood-2021-145764
Published: 2021
Journal Articles

Racial Disparities in Telemedicine Uptake during the COVID-19 Pandemic Among Patients with Hematologic Malignancies in the United States

Natalia Neparidze, Krystal W. Lau, Xiaoliang Wang, Amy J. Davidoff, Scott F. Huntington, Omer Hassan Jamy, Gregory Calip, Harsh Shah, Deborah M. Stephens, Rebecca A. Miksad, Ravi Parikh, Samuel Takvorian, Gaurav Goyal, Erlene K Seymour
Journal: Blood
Blood (2021) 138 (Supplement 1): 1973.
DOI: https://doi.org/10.1182/blood-2021-153787
Published: 2021
Journal Articles

Safety and Efficacy of Ibrutinib Maintenance (I-M) Following Frontline Induction in Mantle Cell Lymphoma (MCL) with Sequential Assessment of Changes in NGS-MRD

Reem Karmali, Jeremy S. Abramson, Deborah M. Stephens, Jeffrey A Barnes, Jason Kaplan, Jane N. Winter, Shuo Ma, Juehua Gao, Adam M Petrich, Ephraim Hochberg, Tak Takvorian, Frank Kuhr, Lik Wee Lee, Valerie Nelson, Leo I. Gordon, Barbara Pro
Journal: Blood
Blood (2021) 138 (Supplement 1): 3530.
DOI: https://doi.org/10.1182/blood-2021-144707
Published: 2021
Journal Articles

Randomized, Phase III Study of Early Intervention with Venetoclax and Obinutuzumab Versus Delayed Therapy with Venetoclax and Obinutuzumab in Newly Diagnosed Asymptomatic High-Risk Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): Evolve CLL/SLL Study (SWOG S1925; NCT#04269902)

Deborah M. Stephens, Anna Moseley, Brian T. Hill, John M. Pagel, Mazyar Shadman, Michael Fisch, Alexey V. Danilov, David Ng, Anthony R. Mato, Danielle M. Brander, Megan Othus, Steven Coutre, Susan M. O'Brien, Harry P. Erba
Journal: Blood
Blood (2021) 138 (Supplement 1): 2630.
DOI: https://doi.org/10.1182/blood-2021-144780
Published: 2021
Journal Articles

Investigating the Addition of Ianalumab (VAY736) to Ibrutinib in Patients with Chronic Lymphocytic Leukemia (CLL) on Ibrutinib Therapy: Results from a Phase Ib Study

Kerry A. Rogers, Ian W. Flinn, Deborah M. Stephens, Thomas J. Kipps, Sarah Larson, Carolyn McGarry, Nadia B. Hassounah, Liangke Connie Gou, Janghee Woo, John C. Byrd
Journal: Blood
Blood (2021) 138 (Supplement 1): 2631.
DOI: https://doi.org/10.1182/blood-2021-147775
Published: 2021
Journal Articles

Chronic Lymphocytic Leukemia Comorbidity Index (CLL-CI), a Novel Comorbidity Measure, Predicts Outcomes in the Context of Targeted Agents and in a Large National Registry

Max J. Gordon, Andy Kaempf, Emelie Rotbain, Andrea Sitlinger, Geoffrey Shouse, Matthew Mei, Danielle M. Brander, Tareq Salous, Brian T. Hill, Michael Choi, Jonathon B. Cohen, Deborah M. Stephens, Dan O. Persky, Krish Patel, Mazyar Shadman, Byung Park, Carsten Utoft Niemann, Alexey V. Danilov
Journal: Blood
Blood (2021) 138 (Supplement 1): 2637.
DOI: https://doi.org/10.1182/blood-2021-148253
Published: 2021
Journal Articles

Practice Patterns Pre-CART for Aggressive B-Cell Lymphomas: Patient Selection and Real World Salvage and Bridging Practices

Imran Nizamuddin, Kevin A. David, Jonathon B. Cohen, Vaishalee P. Kenkre, Geoffrey Shouse, Brian T. Hess, Thomas A. Ollila, Deborah M. Stephens, Sayan Mullick Chowdhury, Robert Ferdman, Kaitlyn O'Shea, Jieqi Liu, Jason T. Romancik, Joanna C. Zurko, Rahul S. Bhansali, Elyse I. Harris, McKenzie Sorrell, Rebecca Masel, Lindsey Fitzgerald, Carlos Galvez, Shuo Ma, Jane N. Winter, Barbara Pro, Leo I. Gordon, Alexey V. Danilov, Nirav N. Shah, Stefan K. Barta, Narendranath Epperla, Pallawi Torka, Reem Karmali
Journal: Blood
Blood (2021) 138 (Supplement 1): 532.
DOI: https://doi.org/10.1182/blood-2021-147033
Published: 2021
Journal Articles

Impact of Comorbidities on Outcomes and Toxicity in Patients Treated with CAR T-Cell Therapy for Diffuse Large B Cell Lymphoma (DLBCL): A Multicenter Rwe Study

Geoffrey Shouse, Andy Kaempf, David Yashar, Audrey M. Sigmund, Gordon Smilnak, Steven M. Bair, Agrima Mian, Lindsey Fitzgerald, Amneet Bajwa, Samantha Jaglowski, Neil Bailey, Mazyar Shadman, Krish Patel, Deborah M. Stephens, Manali Kamdar, Brian T. Hill, Jordan Gauthier, Reem Karmali, Adam S Kittai, Alexey V. Danilov
Journal: Blood
Blood (2021) 138 (Supplement 1): 529.
DOI: https://doi.org/10.1182/blood-2021-149735
Published: 2021
Journal Articles

Extranodal Presentation in Limited Stage DLBCL As a Prognostic Marker in Three Sequential SWOG Trials S0014, S0313 and S1001 (NCT00005089, NCT00070018, NCT01359592)

Deborah M. Stephens, Hongli Li, Louis S. Constine, John P. Leonard, Brad S. Kahl, Joo Y Song, Michael L. Leblanc, Thomas J. Fitzgerald, Sonali M. Smith, Jonathan W. Friedberg, Dan O. Persky
Journal: Blood
Blood (2021) 138 (Supplement 1): 1423.
DOI: https://doi.org/10.1182/blood-2021-147938
Published: 2021
Journal Articles

Impact of the COVID-19 Pandemic on in-Person Visit Rates Among Patients with Hematologic Malignancies in the United States

Gaurav Goyal, Krystal W. Lau, Xiaoliang Wang, Amy J. Davidoff, Scott F. Huntington, Omer Hassan Jamy, Gregory Calip, Harsh Shah, Deborah M. Stephens, Rebecca A. Miksad, Ravi Parikh, Samuel Takvorian, Natalia Neparidze, Erlene K Seymour
Journal: Blood
Blood (2021) 138 (Supplement 1): 1930.
DOI: https://doi.org/10.1182/blood-2021-153625
Published: 2021
Journal Articles

Preliminary Efficacy and Safety of MK-1026, a Non-Covalent Inhibitor of Wild-Type and C481S Mutated Bruton Tyrosine Kinase, in B-Cell Malignancies: A Phase 2 Dose Expansion Study

Jennifer A. Woyach, Ian W. Flinn, Farrukh T. Awan, Herbert Eradat, Danielle M. Brander, Michael Tees, Sameer A. Parikh, Tycel Phillips, Wayne Wang, Nishitha M. Reddy, Mohammed Z.H. Farooqui, John C. Byrd, Deborah M. Stephens
Journal: Blood
Blood (2021) 138 (Supplement 1): 392.
DOI: https://doi.org/10.1182/blood-2021-148672
Published: 2021
Journal Articles

Resistance to Bruton tyrosine kinase inhibitors: the Achilles heel of their success story in lymphoid malignancies

Clinical Trials & Observations
Deborah M. Stephens, John C. Byrd
Journal: Blood
Blood (2021) 138 (13): 1099–1109.
DOI: https://doi.org/10.1182/blood.2020006783
Published: 2021
Journal Articles

Acalabrutinib in treatment-naive chronic lymphocytic leukemia

Clinical Trials & Observations
John C. Byrd, Jennifer A. Woyach, Richard R. Furman, Peter Martin, Susan O’Brien, Jennifer R. Brown, Deborah M. Stephens, Jacqueline C. Barrientos, Stephen Devereux, Peter Hillmen, John M. Pagel, Ahmed Hamdy, Raquel Izumi, Priti Patel, Min Hui Wang, Nitin Jain, William G. Wierda
Journal: Blood
Blood (2021) 137 (24): 3327–3338.
DOI: https://doi.org/10.1182/blood.2020009617
Published: 2021
Includes: Supplemental data
Journal Articles

CNS Prophylaxis during Front-Line Therapy in Aggressive Non-Hodgkin Lymphomas: Real-World Outcomes and Practice Patterns from 19 US Academic Institutions

Victor M. Orellana-Noia, MD, Daniel R Reed, MD, Jeremy M Sen, PharmD, BCOP, Christian Barlow, MD, Mary-Kate Malecek, MD, Brad S. Kahl, MD, Michael A Spinner, MD, Ranjana Advani, MD, Timothy J Voorhees, MD, Anson Snow, MD, Natalie S Grover, MD, Amy Ayers, MPH, Jason T. Romancik, MD, Yuxin Liu, MD, Scott F. Huntington, MD MPH, Julio C. Chavez, MD, Hayder Saeed, MD, Aleksandr Lazaryan, MDPhDMPH, Vikram Raghunathan, MD, Stephen E. Spurgeon, MD, Thomas A Ollila, MD, Christopher Del Prete, MD, Adam J Olszewski, MD, Emily C. Ayers, MD, Daniel J. Landsburg, MD, Benjamin Echalier, Jun Lee, Manali Kamdar, MD, Paolo F Caimi, MD, Timothy Fu, MD, Jieqi Liu, MD, Kevin A. David, MD, Hanan Alharthy, MD, Jennie Y. Law, MD, Reem Karmali, MDMSc, Harsh Shah, DO, Deborah M. Stephens, DO, Ajay Major, MDMBA, Alexandra E Rojek, MD, Sonali M. Smith, MD, Amulya Yellala, MBBS, Avyakta Kallam, MD, Shazia Nakhoda, MD, Nadia Khan, MD, Jonathon B. Cohen, MDMS, Craig A. Portell, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 27–28.
DOI: https://doi.org/10.1182/blood-2020-134798
Published: 2020
Journal Articles

Transcend CLL 004: Phase 1 Cohort of Lisocabtagene Maraleucel (liso-cel) in Combination with Ibrutinib for Patients with Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

William G. Wierda, MD PhD, Kathleen A. Dorritie, MD, Javier Munoz, MD, Deborah M. Stephens, DO, Scott R. Solomon, MD, Heidi H. Gillenwater, MD, Lucy Gong, PharmD, Lin Yang, PhD, Ken Ogasawara, PhD MPH, Jerill Thorpe, BS, Tanya Siddiqi, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
DOI: https://doi.org/10.1182/blood-2020-140622
Published: 2020