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David Taussig
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Journal Articles

Gilteritinib for Relapsed Acute Myeloid Leukaemia with FLT3 Mutation during the COVID-19 Pandemic: Real World Experience from the UK National Health Service

Jad Othman, Usman Afzal, Ruebina Amofa, Michael J Austin, Alex Bashford, Edward Belsham, Jennifer Byrne, Thomas Coats, Raymond Dang, Mike Dennis, Saniya Dhawan, Johnathon Elliot, Sebastian Francis, Paolo Gallipoli, Katherine Hodgson, Charlotte Kallmeyer, Manish Jain, Vana Katsomitrou, Anjum Khan, Asim Khwaja, Seye Kolade, Pramila Krishnamurthy, Annie Latif, John Laurie, Michael Lim, (Justin) Ching Ting Loke, Cara Manson, Scott R. Marshall, Behnaz Mobashwera, Sreetharan Munisamy, Duncan Murray, Vidhya Murthy, Renuka Palanicawandar, Jamie Saunders, Matthew Smith, Katherine Smith, Alex Sternberg, David Taussig, Tom Taylor, Sylvie D Freeman, Charles Craddock, Richard Dillon
Journal: Blood
Blood (2021) 138 (Supplement 1): 1254.
DOI: https://doi.org/10.1182/blood-2021-150169
Published: 2021
Journal Articles

Venetoclax with Azacitidine or Low Dose Cytarabine As an Alternative to Intensive Chemotherapy in Fit Adults during the COVID19 Pandemic: Real World Data from the UK National Health Service

Jad Othman, Mariam Amer, Ruebina Amofa, Laura Anderson, Michael J Austin, Alex Bashford, Edward Belsham, Jesca Boot, Victoria Louise Campbell, Thomas Coats, Angela Collins, Charles Crawley, Francesca Crolla, Joe W Cross, Chris Dalley, Raymond Dang, Mike Dennis, Saniya Dhawan, Johnathon Elliott, Sofia Galli, Paolo Gallipoli, Katherine Hodgson, Manish Jain, Pallavi Kalkur, Vana Katsomitrou, Anjum Khan, Asim Khwaja, Pramila Krishnamurthy, Annie Latif, John Laurie, Michael Lim, Eleana Loizou, Justin Loke, Deepak Mannari, Cara Manson, Scott R. Marshall, Behnaz Mobashwera, Vidhya Murthy, Odong Ochaya, Shahzad Orthi, Renuka Palanicawandar, Srinivas Pillai, Dominika Radzova, Adam Rye, Jamie Saunders, Matthew Smith, David Taussig, Tom Taylor, Richard Whitmill, Rui Zhao, Sylvie D Freeman, Charles Craddock, Richard Dillon
Journal: Blood
Blood (2021) 138 (Supplement 1): 2321.
DOI: https://doi.org/10.1182/blood-2021-149685
Published: 2021
Journal Articles

Molecular Characteristics of Response to Olutasidenib (FT-2102) in Patients with Relapsed/Refractory mIDH1 Acute Myeloid Leukemia

Stephane De Botton, Karen Yee, Christian Recher, Andrew H. Wei, Pau Montesinos, David Taussig, Arnaud Pigneux, Thorsten Braun, Antonio Curti, Jordi Esteve, Carolyn Grove, Brian A. Jonas, Asim Khwaja, Olivier Legrand, Pierre Peterlin, Montserrat Arnan Sangerman, William G. Blum, Daniela Cilloni, Devendra Hiwase, Joseph G. Jurcic, Jürgen Krauter, Xavier Thomas, Justin Watts, Jay Yang, Zihao Xin, Alex Sedkov, Sylvie Guichard, Jennifer Sweeney, Christophe Marzac, Jorge E. Cortes, Pierre Fenaux
Journal: Blood
Blood (2021) 138 (Supplement 1): 2351.
DOI: https://doi.org/10.1182/blood-2021-144912
Published: 2021
Journal Articles

Priming Death Receptor Mediated Apoptosis with Arginine Starvation Sensitises Arginine Auxotrophic B-ALL to CAR-T

Michael J Austin, Leena Halim, Farideh Miraki-Moud, David Taussig, John Bomalaski, John Maher, John Gribben, Peter Szlosarek, Bela Wrench
Journal: Blood
Blood (2021) 138 (Supplement 1): 2787.
DOI: https://doi.org/10.1182/blood-2021-151734
Published: 2021
Journal Articles

Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia

Ana Rio-Machin, Pedro Casado-Izquierdo, Juho Miettinen, PhD, Findlay Bewicke-Copley, PhD MSc, BSc, Naeem Khan, PhD, Jonas Demeulemeester, Szilvia Krizsán, MD, Jiexin Zheng, Christopher Middleton, Wencheng Yin, William Grey, Farideh Miraki-Moud, PhD, Janet Matthews, Marianne Grantham, Kevin Rouault-Pierre, PhD, Krister Wennerberg, Alun Parsons, Hannah Armes, Karina EM Close, Doriana Di Bella, James Cavenagh, Sylvie D Freeman, Peter Van Loo, Csaba Bödör, PhD, Kimmo Porkka, Caroline A Heckman, PhD, Jun Wang, PhD, David Taussig, Dominique Bonnet, PhD, Jean-Baptiste Cazier, PhD, Pedro Cutillas, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
DOI: https://doi.org/10.1182/blood-2020-141345
Published: 2020
Journal Articles

Molecular MRD status and outcome after transplantation in NPM1 -mutated AML

Clinical Trials & Observations
Richard Dillon, Robert Hills, Sylvie Freeman, Nicola Potter, Jelena Jovanovic, Adam Ivey, Anju Shankar Kanda, Manohursingh Runglall, Nicola Foot, Mikel Valganon, Asim Khwaja, Jamie Cavenagh, Matthew Smith, Hans Beier Ommen, Ulrik Malthe Overgaard, Mike Dennis, Steven Knapper, Harpreet Kaur, David Taussig, Priyanka Mehta, Kavita Raj, Igor Novitzky-Basso, Emmanouil Nikolousis, Robert Danby, Pramila Krishnamurthy, Kate Hill, Damian Finnegan, Samah Alimam, Erin Hurst, Peter Johnson, Anjum Khan, Rahuman Salim, Charles Craddock, Ruth Spearing, Amanda Gilkes, Rosemary Gale, Alan Burnett, Nigel H. Russell, David Grimwade
Journal: Blood
Blood (2020) 135 (9): 680–688.
DOI: https://doi.org/10.1182/blood.2019002959
Published: 2020
Includes: Supplemental data
Journal Articles

Efficacy and Safety of Azacitidine (AZA) in Combination with the Anti-PD-L1 Durvalumab (durva) for the Front-Line Treatment of Older Patients (pts) with Acute Myeloid Leukemia (AML) Who Are Unfit for Intensive Chemotherapy (IC) and Pts with Higher-Risk Myelodysplastic Syndromes (HR-MDS): Results from a Large, International, Randomized Phase 2 Study

Amer M. Zeidan, MBBS, MHS, James Cavenagh, Maria Teresa Voso, David Taussig, Mar Tormo, Isaac Boss, Wilbert B. Copeland, Vanessa E. Gray, Alessandro Previtali, Tim O'Connor, Shelonitda Rose, CL Beach, Lewis R. Silverman
Journal: Blood
Blood (2019) 134 (Supplement_1): 829.
DOI: https://doi.org/10.1182/blood-2019-122896
Published: 2019
Journal Articles

Rapid Elimination of NPM1 Mutant Measurable Residual Disease (MRD) Using Low Intensity Venetoclax-Based Combinations in Acute Myeloid Leukemia (AML)

Ing S Tiong, MBChB,FRACP,FRCPA, Richard Dillon, MA, PhD MRCP, FRCPath, Adam Ivey, BSc, MSc, PhD, Tse-Chieh Teh, MBBS,PhDFRACP, FRCPA, Catherine Vassili, RN,MN, Vanessa Roma Donati, RN, David Taussig, PhD MRCP, FRCPath, Nicola Potter, PhD, Jelena Jovanovic, PhD, Anju Kanda, MSc, Manohursingh Runglall, MSc, Nicola Foot, MSc, Mikel Valganon, PhD, Nigel H. Russell, MD, Kavita Raj, MD PhD, Anthony P Schwarer, MD MBBS (Hons), FRACP, FRCPA, Chun Yew Fong, MBBS,PhDFRACP,FRCPA, Andrew Grigg, Steven Knapper, DM, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 2648.
DOI: https://doi.org/10.1182/blood-2019-123899
Published: 2019
Journal Articles

Comparison of Three Assays for Identification of IDH Mutations in AML

Sara Ribeiro, BSc, Dorte Wren, PhDFRCPath, Lisa Thompson, PhD MSc, FIBMS, Michael Hubank, PhD, David Taussig, PhD MRCP, FRCPath
Journal: Blood
Blood (2019) 134 (Supplement_1): 5195.
DOI: https://doi.org/10.1182/blood-2019-126494
Published: 2019
Journal Articles

Excellent Response to Blinatumomab in Children and Young Adults with Refractory B Lineage Acute Lymphoblastic Leukaemia for Persistent MRD or after Debulking Chemotherapy for Higher Disease Burden

Vasudha Rao, MD, Katherine Clesham, Jack Luke Bartram, MD, Phil Ancliff, Sara Ghorashian, FRCPath, PhD, David O'Connor, Vesna Pavasovic, Anupama Rao, MD, Sujith Samarasinghe, Carole Cairns, David Marks, David Taussig, PhD MRCP, FRCPath, Ajay Vora, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 5201.
DOI: https://doi.org/10.1182/blood-2018-99-117051
Published: 2018
Journal Articles

Mechanically Disaggregated Unfixed Trephine Biopsies Can be Used for Diagnostic Immunophenotyping in Acute Leukaemia

David Taussig, PhD MRCP, FRCPath, Ricardo Morilla, Alison Morilla, Kate Moss, Veselka Nikolova, Kelly Marquardt, Sophie Duke, Kasia Adamowska, Lynnsay Fuller, Ala Taifoor, Naomi Johnson, Athanasia Zeisig, Ayad Atra, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5125.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.5125.5125
Published: 2017
Journal Articles

Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia

Floriana Manodoro, Jacek Marzec, Tracy Chaplin, Farideh Miraki-Moud, Eva Moravcsik, Jelena V. Jovanovic, Jun Wang, Sameena Iqbal, David Taussig, David Grimwade, John G. Gribben, Bryan D. Young, Silvana Debernardi
Journal: Blood
Blood (2014) 123 (13): 2066–2074.
DOI: https://doi.org/10.1182/blood-2012-12-469833
Published: 2014
Includes: Supplemental data
Journal Articles

Differential and tumor-specific expression of CD160 in B-cell malignancies

Timothy W. Farren, Jerome Giustiniani, Feng-Ting Liu, Dimitris A. Tsitsikas, Marion G. Macey, James D. Cavenagh, Heather E. Oakervee, David Taussig, Adrian C. Newland, Maria Calaminici, Armand Bensussan, Michael Jenner, John G. Gribben, Samir G. Agrawal
Journal: Blood
Blood (2011) 118 (8): 2174–2183.
DOI: https://doi.org/10.1182/blood-2011-02-334326
Published: 2011
Includes: Supplemental data
Journal Articles

Differential Gene Expression Profile Identifies the Nature of T Cell Defects in AML Patients at Diagnosis.

Rifca Le Dieu, MBBS, Alan G Ramsay, PhD, David Taussig, PhD, Richard Mitter, John G. Gribben, MD, DSc
Journal: Blood
Blood (2008) 112 (11): 1186.
DOI: https://doi.org/10.1182/blood.V112.11.1186.1186
Published: 2008
Journal Articles

CD3+/CD56+ Cells, but Not Natural Killer T Cells, Are Increased in Peripheral Blood of Untreated Patients with Leukemia.

Rifca Le Dieu, MB, BS, David Taussig, PhD, Finlay MacDougal, Andrew Lister, MD, John G. Gribben, DSc
Journal: Blood
Blood (2007) 110 (11): 1815.
DOI: https://doi.org/10.1182/blood.V110.11.1815.1815
Published: 2007
Journal Articles

AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML

Clinical Trials & Observations
Daniel J. Pearce, David Taussig, Kazem Zibara, Lan-Lan Smith, Christopher M. Ridler, Claude Preudhomme, Bryan D. Young, Ama Z. Rohatiner, T. Andrew Lister, Dominique Bonnet
Journal: Blood
Blood (2006) 107 (3): 1166–1173.
DOI: https://doi.org/10.1182/blood-2005-06-2325
Published: 2006
Journal Articles

Gene Expression Profiling Reveals Fundamental Differences between Leukemic Stem Cells (Lin-CD34+CD38−) and Mature Blasts (Lin−CD34+CD38+) of Acute Myeloid Leukaemia (AML) Patients.

Kazem Zibara, PhD, Daniel Pearce, Ph.D, David Taussig, MD, Spyros Skoulakis, Ph.D, Simon Tomlinson, Ph.D, Emilie Bureau, Bryan D. Young, Ph.D, Dominique Bonnet, Ph.D
Journal: Blood
Blood (2005) 106 (11): 1377.
DOI: https://doi.org/10.1182/blood.V106.11.1377.1377
Published: 2005
Journal Articles

A High ALDH Activity Identifies Both Normal and Leukemic Stem Cells.

Daniel J. Pearce, David Taussig, Catherine Simpson, Dominique Bonnet
Journal: Blood
Blood (2004) 104 (11): 4467.
DOI: https://doi.org/10.1182/blood.V104.11.4467.4467
Published: 2004