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David J. Young
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Journal Articles

Arginine metabolism regulates human erythroid differentiation through hypusination of eIF5A

Pedro Gonzalez-Menendez, Ira Phadke, Meagan E Olive, Axel Joly, Julien Papoin, Hongxia Yan, Jérémy Galtier, Jessica Platon, Sun Woo Sophie Kang, Kathy L. McGraw, Marie Daumur, Marie Pouzolles, Taisuke Kondo, Stéphanie Boireau, Franciane Paul, David J Young, Sylvain Lamure, Raghavendra G Mirmira, Anu Narla, Guillaume Cartron, Cynthia E. Dunbar, Myriam Boyer-Clavel, Natalie Porat-Shliom, Valerie Dardalhon, Valerie S Zimmermann, Marc Sitbon, Thomas Dever, Narla Mohandas, Lydie M Da Costa, Namrata D. Udeshi, Lionel Blanc, Sandrina Kinet, Naomi Taylor
Journal: Blood
Blood blood.2022017584.
DOI: https://doi.org/10.1182/blood.2022017584
Published: 2023
Includes: Supplemental data
Journal Articles

Treatment of Refractory Diamond-Blackfan Anemia with Eltrombopag

Brynn B Duncan, Jennifer Lotter, Jeanine Superata, Ma Evette Barranta, Ivana Darden, Sanjay Venugopal, Colin O. Wu, Cynthia E. Dunbar, David J. Young
Journal: Blood
Blood (2022) 140 (Supplement 1): 5824–5825.
DOI: https://doi.org/10.1182/blood-2022-160297
Published: 2022
Journal Articles

Granulocyte Transfusions As an Adjunctive Therapy in Severe Aplastic Anemia

Roma V. Rajput, Vaani Shah, Ruba Shalhoub, Kamille West-Mitchell, Cathy Conry-Cantilena, David J. Young, Cynthia E. Dunbar, Bhavisha A. Patel, Richard W. Childs, Neal S. Young, Colin O. Wu, Emma M. Groarke, Shelley S. Kalsi
Journal: Blood
Blood (2022) 140 (Supplement 1): 8556–8557.
DOI: https://doi.org/10.1182/blood-2022-162595
Published: 2022
Journal Articles

Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell–extrinsic contributions to erythropoiesis

Raymond T. Doty, Xing Fan, David J. Young, Jialiu Liang, Komudi Singh, Zahra Pakbaz, Ronan Desmond, Sara K. Young-Baird, Settara C. Chandrasekharappa, Frank X. Donovan, Susan R. Phelps, Thomas Winkler, Cynthia E. Dunbar, Janis L. Abkowitz
Journal: Blood
Blood (2022) 139 (23): 3439–3449.
DOI: https://doi.org/10.1182/blood.2021013507
Published: 2022
Includes: Supplemental data
Journal Articles

Strong Predictors of Chromosomal Aberrations and Myeloid Neoplasia Following Immunosuppression Therapy for Severe Aplastic Anemia: A Retrospective Cohort Study

Emma M. Groarke, Bhavisha A. Patel, Ruba Shalhoub, Fernanda Gutierrez-Rodrigues, Parth Desai, Harshraj Leuva, Casey Paton, Nina Spitofsky, Jennifer Lotter, Olga Rios, Richard W. Childs, David J. Young, Alina Dulau-Florea, Cynthia E. Dunbar, Katherine R. Calvo, Colin O. Wu, Neal S. Young
Journal: Blood
Blood (2021) 138 (Supplement 1): 601.
DOI: https://doi.org/10.1182/blood-2021-146070
Published: 2021
Journal Articles

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

David J Young, MDPhD, Xing Fan, MD, Emma Groarke, MD, Bhavisha A Patel, MD, Ronan Desmond, MD, Thomas Winkler, MD, Andre Larochelle, MD PhD, Katherine R. Calvo, MD PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
DOI: https://doi.org/10.1182/blood-2020-141375
Published: 2020
Journal Articles

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag

Clinical Trials & Observations
Thomas Winkler, Xing Fan, James Cooper, Ronan Desmond, David J. Young, Danielle M. Townsley, Phillip Scheinberg, Sophia Grasmeder, Andre Larochelle, Marie Desierto, Janet Valdez, Jennifer Lotter, Colin Wu, Ruba N. Shalhoub, Katherine R. Calvo, Neal S. Young, Cynthia E. Dunbar
Journal: Blood
Blood (2019) 133 (24): 2575–2585.
DOI: https://doi.org/10.1182/blood.2019000478
Published: 2019
Journal Articles

Combinatorial Approaches to Overcome Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

David J Young, MD PhD, Jun O Liu, PhD, Donald Small, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1362.
DOI: https://doi.org/10.1182/blood-2018-99-118820
Published: 2018
Journal Articles

A Novel Method for Overcoming Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors

David J Young, MD PhD, Donald Small, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1241.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1241.1241
Published: 2017