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Journal Articles

Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions

Blood blood.2021014875.

DOI: https://doi.org/10.1182/blood.2021014875

Published: 2022

Includes: Supplemental data

Journal Articles

Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell–extrinsic contributions to erythropoiesis

Raymond T. Doty, Xing Fan, David J. Young, Jialiu Liang, Komudi Singh, Zahra Pakbaz, Ronan Desmond, Sara K. Young-Baird, Settara C. Chandrasekharappa, Frank X. Donovan, Susan R. Phelps, Thomas Winkler, Cynthia E. Dunbar, Janis L. Abkowitz

Blood (2022) 139 (23): 3439–3449.

DOI: https://doi.org/10.1182/blood.2021013507

Published: 2022

Includes: Supplemental data

Journal Articles

Evaluation of the Relationship between Clonal Hematopoiesis and Severe COVID-19 Disease in Rhesus Macaques

Taehoon Shin, Yifan Zhou, So Gun Hong, John-Paul Todd, Shayne Andrew, Barbara Flynn, Matthew Gagne, Ian Moore, Anthony Cook, Mark Lewis, Kathryn Foulds, Robert Seder, Daniel Douek, Mario Roederer, Cynthia E. Dunbar

Blood (2021) 138 (Supplement 1): 3279.

DOI: https://doi.org/10.1182/blood-2021-152628

Published: 2021

Journal Articles

Genomic-Based Machine Learning Towards Prediction of the Etiology of Bone Marrow Failure Syndromes

Blood (2021) 138 (Supplement 1): 2182.

DOI: https://doi.org/10.1182/blood-2021-151258

Published: 2021

Journal Articles

Rhesus Macaques As a Preclinical Model Organism for RUNX1-FPD

Byung-Chul Lee, Yifan Zhou, Erica Bresciani, Neval Ozkaya, Taehoon Shin, So Gun Hong, Paul P. Liu, Cynthia E. Dunbar

Blood (2021) 138 (Supplement 1): 2185.

DOI: https://doi.org/10.1182/blood-2021-152863

Published: 2021

Journal Articles

Single Cell RNA-Seq Characterization of an Adaptive Population of NK Cells after Primary CMV Infection in Rhesus Macaques

Stefan Cordes, Ryland D Mortlock, Lauren Truitt, Di Yang, Diego A Espinoza, Xing Fan, Daniel Ram, Matilda Mostrom, Dollnovan Tran, Lesli Sprehe, R. Keith Reeves, Robert E. Donahue, Michael Kelly, Jinguo Chen, So Gun Hong, Amitinder Kaur, Chuanfeng Wu, Cynthia E. Dunbar

Blood (2021) 138 (Supplement 1): 193.

DOI: https://doi.org/10.1182/blood-2021-153667

Published: 2021

Journal Articles

Strong Predictors of Chromosomal Aberrations and Myeloid Neoplasia Following Immunosuppression Therapy for Severe Aplastic Anemia: A Retrospective Cohort Study

Emma M. Groarke, Bhavisha A. Patel, Ruba Shalhoub, Fernanda Gutierrez-Rodrigues, Parth Desai, Harshraj Leuva, Casey Paton, Nina Spitofsky, Jennifer Lotter, Olga Rios, Richard W. Childs, David J. Young, Alina Dulau-Florea, Cynthia E. Dunbar, Katherine R. Calvo, Colin O. Wu, Neal S. Young

Blood (2021) 138 (Supplement 1): 601.

DOI: https://doi.org/10.1182/blood-2021-146070

Published: 2021

Journal Articles

Tissue-Resident Clonal Expansions of Rhesus Macaque NK Cells

Chuanfeng Wu, Ryland D Mortlock, Taehoon Shin, Stefan Cordes, Xing Fan, Jason Brenchley, David A Allan, So Gun Hong, Cynthia E. Dunbar

Blood (2021) 138 (Supplement 1): 998.

DOI: https://doi.org/10.1182/blood-2021-146220

Published: 2021

Journal Articles

Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration

So Gun Hong, Noriko Sato, Fanny Legrand, Manasi Gadkari, Michelle Makiya, Kindra Stokes, Katherine N. Howe, Shiqin Judy Yu, Nathaniel Seth Linde, Randall R. Clevenger, Timothy Hunt, Zonghui Hu, Peter L. Choyke, Cynthia E. Dunbar, Amy D. Klion, Luis M. Franco

Blood (2020) 136 (23): 2667–2678.

DOI: https://doi.org/10.1182/blood.2020005161

Published: 2020

Includes: Multimedia, Supplemental data

Journal Articles

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

David J Young, MDPhD, Xing Fan, MD, Emma Groarke, MD, Bhavisha A Patel, MD, Ronan Desmond, MD, Thomas Winkler, MD, Andre Larochelle, MD PhD, Katherine R. Calvo, MD PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2020) 136 (Supplement 1): 39–40.

DOI: https://doi.org/10.1182/blood-2020-141375

Published: 2020

Journal Articles

Macaque CRISPR/Cas9 Age-Related Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Mutated Clones and Applicability for Testing Mitigation Approaches

Taehoon Shin, Shirley Chen, BS, Stefan Cordes, MD PhD, Yifan Zhou, MS, Byung-Chul Lee, PhD, Aisha Aljanahi, BS, So Gun Hong, PhD, Robert E. Donahue, VMD, Kyung-Rok Yu, PhD, Cynthia E. Dunbar, MD

Blood (2020) 136 (Supplement 1): 27–28.

DOI: https://doi.org/10.1182/blood-2020-140770

Published: 2020

Journal Articles

A Diamond-Blackfan Anemia Patient's Response to Eltrombopag and Genomic Analysis in Different Lineages

Xing Fan, MD, David Young, MD, Thomas Winkler, MD, Zahra Pakbaz, MD, Stephanie Sellers, Ma Evette Barranta, Cynthia E. Dunbar, MD

Blood (2020) 136 (Supplement 1): 16–17.

DOI: https://doi.org/10.1182/blood-2020-138577

Published: 2020

Journal Articles

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Kristopher D Marjon, PhD, James Y Chen, MD PhD, Jiaqi Duan, MS, Timothy S Choi, BS, Kavitha Sompalli, MS, Dongdong Feng, PhD, Ofelia Mata, Sharline Chen, B.S., Leslie Kean, MD PhD, Mwe Mwe Chao, MD, Mark Chao, MD PhD, Chris H Takimoto, MD PhD, Balaji Agoram, PhD, Cynthia E. Dunbar, MD, Ravi Majeti, MD PhD, Irving L Weissman, MD, Jie Liu, PhD MD, Jens-Peter Volkmer, MD

Blood (2019) 134 (Supplement_1): 4428.

DOI: https://doi.org/10.1182/blood-2019-131490

Published: 2019

Journal Articles

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag

Thomas Winkler, Xing Fan, James Cooper, Ronan Desmond, David J. Young, Danielle M. Townsley, Phillip Scheinberg, Sophia Grasmeder, Andre Larochelle, Marie Desierto, Janet Valdez, Jennifer Lotter, Colin Wu, Ruba N. Shalhoub, Katherine R. Calvo, Neal S. Young, Cynthia E. Dunbar

Blood (2019) 133 (24): 2575–2585.

DOI: https://doi.org/10.1182/blood.2019000478

Published: 2019

Journal Articles

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

Tae-Hoon Shin, Eun Jung Baek, Marcus A. F. Corat, Shirley Chen, Jean-Yves Metais, Aisha A. AlJanahi, Yifan Zhou, Robert E. Donahue, Kyung-Rok Yu, Cynthia E. Dunbar

Blood (2019) 133 (23): 2542–2545.

DOI: https://doi.org/10.1182/blood.2019000800

Published: 2019

Includes: Supplemental data

Journal Articles

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

Luigi J. Alvarado, Heather D. Huntsman, Hai Cheng, Danielle M. Townsley, Thomas Winkler, Xingmin Feng, Cynthia E. Dunbar, Neal S. Young, Andre Larochelle

Blood (2019) 133 (19): 2043–2055.

DOI: https://doi.org/10.1182/blood-2018-11-884486

Published: 2019

Includes: Supplemental data

Journal Articles

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Fernanda Gutierrez-Rodrigues, PhD, Carrie Diamond, MD, Ruba Shalhoub, André Pinto, Flávia S Donaires, PhD, Diego V Clé, MD PhD, Luiz Guilherme Darrigo, PhD, Luiz Fernando Catto, MD, Xing Fan, MD, Maria del Pilar Fernandez Ibanez, Sachiko Kajigaya, PhD, Cynthia E. Dunbar, MD, Carmem M. S. Bonfim, MD, Danielle M. Townsley, MD MSc, Rodrigo T. Calado, MD PhD, Neal S. Young, MD

Blood (2018) 132 (Supplement 1): 2587.

DOI: https://doi.org/10.1182/blood-2018-99-115026

Published: 2018

Journal Articles

Single Cell Transcriptome Analysis of GATA2 Deficiency in Hematopoiesis Modeled with Induced Pluripotent Stem Cells

Francis Guitart, BA, Moonjung Jung, MD, Stefan Cordes, MD PhD, Shiqin Yu, Jizhong Zou, So Gun Hong, PhD, Vinh Dang, Diego A Espinoza, BA, Amy Hsu, Steven M. Holland, MD, Danielle M. Townsley, MD MSc, Cynthia E. Dunbar, MD, Thomas Winkler, MD

Blood (2018) 132 (Supplement 1): 5087.

DOI: https://doi.org/10.1182/blood-2018-99-118410

Published: 2018

Journal Articles

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Xing Fan, MD, Thomas Winkler, MD, Ronan Desmond, MD, Bogdan Dumitriu, MD, Danielle M. Townsley, MD MSc, Maria del Pilar Fernandez Ibanez, Fernanda Gutierrez-Rodrigues, PhD, Sophia Grasmeder, RN, Ma Evette Barranta, Diane Madey, Jennifer Lotter, Janet Valdez, Katherine R. Calvo, MD PhD, Colin Wu, PhD, Neal S. Young, MD, Cynthia E. Dunbar, MD

Blood (2018) 132 (Supplement 1): 538.

DOI: https://doi.org/10.1182/blood-2018-99-112994

Published: 2018

Journal Articles

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

Sanggu Kim, PhD, Robert E. Donahue, VMD, Aylin Bonifacino, MS, Mark Metzger, Cynthia E. Dunbar, MD, Irvin Chen, PhD

Blood (2018) 132 (Supplement 1): 4524.

DOI: https://doi.org/10.1182/blood-2018-99-117047

Published: 2018

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NARROW

Macaque Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Disrupted Clones and Utility for Testing Interventions

Studies of a mosaic patient with DBA and chimeric mice reveal erythroid cell–extrinsic contributions to erythropoiesis

Evaluation of the Relationship between Clonal Hematopoiesis and Severe COVID-19 Disease in Rhesus Macaques

Genomic-Based Machine Learning Towards Prediction of the Etiology of Bone Marrow Failure Syndromes

Rhesus Macaques As a Preclinical Model Organism for RUNX1-FPD

Single Cell RNA-Seq Characterization of an Adaptive Population of NK Cells after Primary CMV Infection in Rhesus Macaques

Strong Predictors of Chromosomal Aberrations and Myeloid Neoplasia Following Immunosuppression Therapy for Severe Aplastic Anemia: A Retrospective Cohort Study

Tissue-Resident Clonal Expansions of Rhesus Macaque NK Cells

Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration

Long-Term Eltrombopag for Bone Marrow Failure Depletes Total Body Iron

Macaque CRISPR/Cas9 Age-Related Clonal Hematopoiesis Model Demonstrates Expansion of TET2-Mutated Clones and Applicability for Testing Mitigation Approaches

A Diamond-Blackfan Anemia Patient's Response to Eltrombopag and Genomic Analysis in Different Lineages

An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates

Treatment optimization and genomic outcomes in refractory severe aplastic anemia treated with eltrombopag

CRISPR/Cas9 PIG -A gene editing in nonhuman primate model demonstrates no intrinsic clonal expansion of PNH HSPCs

Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

Towards Improved Decision-Making Based on Genomics in Bone Marrow Failure

Single Cell Transcriptome Analysis of GATA2 Deficiency in Hematopoiesis Modeled with Induced Pluripotent Stem Cells

Eltrombopag for Moderate Aplastic Anemia and Unilineage Cytopenias: Dosing, Long-Term Follow-up, Clonal Evolution and Somatic Mutation Profiling

Long-Term, Clonal Tracking Comparing Autologous Transplantation of G-CSF/SCF-Primed Bone Marrow CD34+ Cells with G-CSF/SCF-Mobilized Peripheral Blood CD34+ Cells in Rhesus Macaques

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American Society of Hematology

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American Society of Hematology

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