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Journal Articles

Eradication of Chronic Myelogenous Leukemia By Inactivation of the Polycomb Group Protein EZH2

Huafeng Xie, PhD, Cong Peng, PhD, Jun Qi, PhD, Giullia Cheloni, Partha Das, PhD, Jialiang Huang, PhD, Minh Nguyen, Shaoguang Li, MD PhD, James E. Bradner, MD, Stuart H. Orkin, MD

Blood (2014) 124 (21): 778.

https://doi.org/10.1182/blood.V124.21.778.778

Published: 2014

Journal Articles

Identification Of BCL11A Structure-Function Domains For Fetal Hemoglobin Silencing

Jian Xu, PHD, Daniel E. Bauer, MD, PhD, Cong Peng, PhD, Elenoe C. Smith, PhD, Stuart H. Orkin, MD

Blood (2013) 122 (21): 435.

https://doi.org/10.1182/blood.V122.21.435.435

Published: 2013

Journal Articles

Nfkb1 Plays a Tumor-Suppressing Role in BCR-ABL-Induced Leukemias

Con Sullivan, Yaoyu Chen, Zhiru Guo, Yi Shan, Cong Peng, Haojian Zhang, Jason Bubier, Thomas Sproule, Derry Roopenian, Shaoguang Li, MD, PhD

Blood (2012) 120 (21): 1666.

https://doi.org/10.1182/blood.V120.21.1666.1666

Published: 2012

Journal Articles

PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia

Zhong-Fa Yang, PhD, Haojian Zhang, Leyuan Ma, Cong Peng, PhD, Yaoyu Chen, Michael Green, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD

Blood (2012) 120 (21): 1672.

https://doi.org/10.1182/blood.V120.21.1672.1672

Published: 2012

Journal Articles

Correction of Murine Sickle Cell Disease Through Interference with Fetal Hemoglobin Silencing

Jian Xu, PhD, Cong Peng, PhD, Vijay G. Sankaran, MD, PhD, Stuart H. Orkin, MD

Blood (2011) 118 (21): 351.

https://doi.org/10.1182/blood.V118.21.351.351

Published: 2011

Journal Articles

Without GABP Transcription Factor, BCR-ABL Cannot Transform HSCs to Leukemic Stem Cells Nor Induce Chronic Myelogenous Leukemia in Mice

Zhongfa Yang, PhD, Cong Peng, Yaoyu Chen, Junling Wang, Xuejun Zhu, Karen Drumea, MD, Shaoguang Li, MD, PhD, Alan G. Rosmarin, MD

Blood (2011) 118 (21): 965.

https://doi.org/10.1182/blood.V118.21.965.965

Published: 2011

Journal Articles

A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia

Yaoyu Chen, Con Sullivan, Cong Peng, Yi Shan, Yiguo Hu, Dongguang Li, Shaoguang Li

Blood (2011) 118 (2): 390–400.

https://doi.org/10.1182/blood-2010-11-316760

Published: 2011

Includes: Supplemental data

Journal Articles

Loss of P-Selectin Promotes the Function of Aged Hematopoietic and Leukemic Stem Cells.

Yaoyu Chen, Sullivan Con, Yiguo Hu, Linghong Kong, Cong Peng, Shaoguang Li, MD, PhD

Blood (2010) 116 (21): 1577.

https://doi.org/10.1182/blood.V116.21.1577.1577

Published: 2010

Journal Articles

PTEN is a tumor suppressor in CML stem cells and BCR-ABL–induced leukemias in mice

Cong Peng, Yaoyu Chen, Zhongfa Yang, Haojian Zhang, Lori Osterby, Alan G. Rosmarin, Shaoguang Li

Blood (2010) 115 (3): 626–635.

https://doi.org/10.1182/blood-2009-06-228130

Published: 2010

Includes: Supplemental data

Journal Articles

DCC-2036: A Novel Switch Pocket Inhibitor of ABL Tyrosine Kinase with Therapeutic Efficacy Against BCR-ABL T315I In Vitro and in a CML Mouse Model.

Richard A. Van Etten, MD, PhD, Wayne W. Chan, BS, Virginia M. Zaleskas, MD, PhD, Peter Evangelista, BS, Katherine Lazarides, BS, Cong Peng, PhD, Shaoguang Li, MD, PhD, Scott C. Wise, PhD, Peter Petillo, PhD, Daniel L. Flynn, PhD

Blood (2007) 110 (11): 463.

https://doi.org/10.1182/blood.V110.11.463.463

Published: 2007

Journal Articles

Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I–induced leukemia and suppresses leukemic stem cells

Cong Peng, Julia Brain, Yiguo Hu, Ami Goodrich, Linghong Kong, David Grayzel, Roger Pak, Margaret Read, Shaoguang Li

Blood (2007) 110 (2): 678–685.

https://doi.org/10.1182/blood-2006-10-054098

Published: 2007

Journal Articles

Curcumin Inhibits Proliferation of Leukemic Cells Expressing P210BCR-ABL or BCR-ABL-T315I and Prolongs Survival of Mice with B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Basem M. William, MD, Ami Goodrich, Cong Peng, MS, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 1887.

https://doi.org/10.1182/blood.V108.11.1887.1887

Published: 2006

Journal Articles

Immunodominant Minor Histocompatibility Antigen-Specific T Lymphocytes Eradicate BCR-ABL-Induced B-ALL and CML without Causing Graft-Versus-Host Disease in Mice.

Yiguo Hu, MD, Thomas Sproule, BS, Cong Peng, MS, Linghong Kong, MD, PhD, Ami Goodrich, Derry Roopenian, PhD, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 3686.

https://doi.org/10.1182/blood.V108.11.3686.3686

Published: 2006

Journal Articles

Increase in Leukemic Stem Cells Is Associated with Acceleration of BCR-ABL-Induced CML in P-Selectin-Deficient Mice.

Linghong Kong, MD, PhD, Yiguo Hu, MD, Cong Peng, MS, Zhu Wang, Ted Duffy, PhD, Ami Goodrich, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 2129.

https://doi.org/10.1182/blood.V108.11.2129.2129

Published: 2006

Journal Articles

IPI-504, a Novel, Orally Active HSP90 Inhibitor, Prolongs Survival of Mice with BCR-ABL T315I CML and B-ALL.

Cong Peng, MS, Julia Brain, PhD, Yiguo Hu, MD, Linghong Kong, MD, PhD, David Grayzel, MD, Roger Pak, PhD, Margaret Read, PhD, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 2183.

https://doi.org/10.1182/blood.V108.11.2183.2183

Published: 2006

Journal Articles

Hsp-90 Inhibition Decreases Survival of BCR-ABL T315I Leukemic Stem Cells in Mice.

Cong Peng, MS, Julia Brain, PhD, Yiguo Hu, MD, Linghong Kong, MD, PhD, Ami Goodrich, David Grayzel, MD, Roger Pak, PhD, Margaret Read, PhD, Shaoguang Li, MD, PhD

Blood (2006) 108 (11): 2184.

https://doi.org/10.1182/blood.V108.11.2184.2184

Published: 2006

Journal Articles

Targeting Chronic Myeloid Leukemia (CML) Stem Cells by BMS-214662 in Mice.

Cong Peng, MS, Yiguo Hu, MD, Francis Y. Lee, PhD, Shaoguang Li, MD, PhD

Blood (2005) 106 (11): 2861.

https://doi.org/10.1182/blood.V106.11.2861.2861

Published: 2005

NARROW

Eradication of Chronic Myelogenous Leukemia By Inactivation of the Polycomb Group Protein EZH2

Identification Of BCL11A Structure-Function Domains For Fetal Hemoglobin Silencing

Nfkb1 Plays a Tumor-Suppressing Role in BCR-ABL-Induced Leukemias

PRKD2 Serine-Threonine Kinase, an Essential Effector of Gabp Transcription Factor, Is Required for Development of Chronic Myelogenous Leukemia

Correction of Murine Sickle Cell Disease Through Interference with Fetal Hemoglobin Silencing

Without GABP Transcription Factor, BCR-ABL Cannot Transform HSCs to Leukemic Stem Cells Nor Induce Chronic Myelogenous Leukemia in Mice

A tumor suppressor function of the Msr1 gene in leukemia stem cells of chronic myeloid leukemia

Loss of P-Selectin Promotes the Function of Aged Hematopoietic and Leukemic Stem Cells.

PTEN is a tumor suppressor in CML stem cells and BCR-ABL–induced leukemias in mice

DCC-2036: A Novel Switch Pocket Inhibitor of ABL Tyrosine Kinase with Therapeutic Efficacy Against BCR-ABL T315I In Vitro and in a CML Mouse Model.

Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I–induced leukemia and suppresses leukemic stem cells

Curcumin Inhibits Proliferation of Leukemic Cells Expressing P210BCR-ABL or BCR-ABL-T315I and Prolongs Survival of Mice with B-Cell Acute Lymphoblastic Leukemia (B-ALL).

Immunodominant Minor Histocompatibility Antigen-Specific T Lymphocytes Eradicate BCR-ABL-Induced B-ALL and CML without Causing Graft-Versus-Host Disease in Mice.

Increase in Leukemic Stem Cells Is Associated with Acceleration of BCR-ABL-Induced CML in P-Selectin-Deficient Mice.

IPI-504, a Novel, Orally Active HSP90 Inhibitor, Prolongs Survival of Mice with BCR-ABL T315I CML and B-ALL.

Hsp-90 Inhibition Decreases Survival of BCR-ABL T315I Leukemic Stem Cells in Mice.

Targeting Chronic Myeloid Leukemia (CML) Stem Cells by BMS-214662 in Mice.

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American Society of Hematology

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American Society of Hematology

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