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Claudia Lengerke
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Journal Articles

A New Severe Congenital Neutropenia Syndrome Associated with Autosomal Recessive COPZ1 Mutations

Natalia Borbaran Bravo, Ekaterina Deordieva, Larissa Doll, Mohammad ElGamacy, Benjamin Dannenmann, Joana Azevedo, Alberto Iannuzzo, Selket Delafontaine, Moritz Lehners, Marius Sebastian Theo Kolodziej, Birte Hernandez Alvarez, Anna-Sophia Hellmuth, Malte Ritter, Betül Findik, Viktoria Zakharova, Sandro Bräuning, Sergey Kandabarau, Claudia Lengerke, Robert Feil, Isabelle Meyts, Jérôme Delon, Markus F. Templin, Marc Sturm, Olaf Rieß, Cornelia Zeidler, Karl Welte, Anna Shcherbina, Maksim Klimiankou, Julia Skokowa
Journal: Blood
Blood blood.2023022576.
https://doi.org/10.1182/blood.2023022576
Published: 2024
Includes: Supplemental data
Journal Articles

Primary Vitreoretinal Lymphoma: A Comprehensive Retrospective Analysis of 65 Cases at Two European Centers

Sina Alexandra Beer, Carola Huber, Michael Sommer, Stefan Wirths, Daniela Süsskind, Claudia Lengerke, David Adrian Merle
Journal: Blood
Blood (2024) 144 (Supplement 1): 4464.
https://doi.org/10.1182/blood-2024-203779
Published: 2024
Journal Articles

Flavopiridol Restores Granulopoiesis in an Experimental Model of Severe Congenital Neutropenia

Benjamin Dannenmann, Masoud Nasri, Larissa Doll, Betül Findik, Franka Bernhard, Sergey Kandabarau, Maksim Klimiankou, Claudia Lengerke, Cornelia Zeidler, Karl Welte, Julia Skokowa
Journal: Blood
Blood (2024) 144 (Supplement 1): 419.
https://doi.org/10.1182/blood-2024-209864
Published: 2024
Journal Articles

Autosomal Recessive COPZ1 Mutations Cause Isolated Severe Neutropenia or Complex Syndrome with Severe Neutropenia

Natalia Alejandra Borbaran Bravo, Ekaterina Deordieva, Larissa Doll, Mohammad Elgamacy, Benjamin Dannenmann, Joana Azevedo, Alberto Iannuzzo, Selket Delafontaine, Moritz Lehners, Marius Kolodziej, Birte Hernandez Alvarez, Anna-Sophia Hellmuth, Malte Ulrich Ritter, Betül Findik, Viktoria Zakharova, Sandro Bräuning, Sergey Kandabarau, Claudia Lengerke, Robert Feil, Isabelle Meyts, Jerome Delon, Markus Templin, Marc Sturm, Olaf Rieß, Cornelia Zeidler, Karl Welte, Anna Shcherbina, Maksim Klimiankou, Julia Skokowa
Journal: Blood
Blood (2024) 144 (Supplement 1): 417.
https://doi.org/10.1182/blood-2024-199069
Published: 2024
Journal Articles

MRC2+ AML Stem Cells Reveal the Role of Proline Metabolism in Venetoclax Resistance

Taylor Scott Mills, Marlon Arnone, Simone Poeschel, Stefan Winter, Jessica Kuebler, Jan Frederic Weller, Anna Maria Stanger, Matthias Schwab, Claudia Lengerke
Journal: Blood
Blood (2024) 144 (Supplement 1): 49.
https://doi.org/10.1182/blood-2024-198643
Published: 2024
Journal Articles

Impact of Allogeneic Hematopoietic Cell Transplantation Post-Sars-Cov-2 Infection: A Retrospective Analysis By the German Cooperative Transplant Study Group

Osama Ahmad, Jan Frederic Weller, Nicolaus Kröger, Eva Wagner Drouet, David Nachbaur, Normann Steiner, Daniel Teschner, Sabrina Kraus, Gesine Bug, Salem Ajib, Johannes Schetelig, Wolfgang Andreas Bethge, Thomas Schroeder, Judith Schaffrath, Lutz Peter Hermann Mueller, Mareike Verbeek, Edgar Jost, Hatice Soysal, Georg-Nikolaus Franke, Stefan Klein, Udo Holtick, Knut Wendelin, Claudia Lengerke, Martin Bornhäuser, Maximilian Christopeit
Journal: Blood
Blood (2024) 144 (Supplement 1): 3554.
https://doi.org/10.1182/blood-2024-204560
Published: 2024
Journal Articles

Modulating G-CSFR Signaling Using De Novo Designed Cytokines

Timo Ullrich, Birte Hernandez Alvarez, Christoph Pollmann, Malte Ulrich Ritter, Jérémy Haaf, Narges Aghaallaei, Jacob Piehler, Ivan Tesakov, Maya El-Riz, Kateryna Maksymenko, Valeriia Hatskovska, Sergey Kandabarau, Maksim Klimiankou, Claudia Lengerke, Karl Welte, Andrei Lupas, Julia Skokowa, Mohammad ElGamacy
Journal: Blood
Blood (2024) 144 (Supplement 1): 4967.
https://doi.org/10.1182/blood-2024-209668
Published: 2024
Journal Articles

Long-Term Immunological Consequences of CD19 CAR T Cell Therapy: Analysis of Infectious Complications and Immune Reconstitution

Andreas Riedel, Jan Frederic Weller, Laurent Phely, Stefan Hug, Christoph Faul, Claudia Lengerke, Wolfgang Andreas Bethge
Journal: Blood
Blood (2024) 144 (Supplement 1): 7248.
https://doi.org/10.1182/blood-2024-210536
Published: 2024
Journal Articles

Dual CD19/CD22-Targeting CAR-T Cells for Richter Transformation: A Case Series

Stefan Hug, Laurent Phely, Andreas Riedel, Simon Killinger, Luca Hensen, Christoph Faul, Wolfgang Andreas Bethge, Claudia Lengerke
Journal: Blood
Blood (2024) 144 (Supplement 1): 6544.
https://doi.org/10.1182/blood-2024-200768
Published: 2024
Journal Articles

Outcomes of Tagraxofusp in Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN): A Multicenter Real-World Analysis

Philipp Berning, David Baden, Philipp Faustmann, Snjezana Janjetovic, Hanna Katharina Zieger, Jan Christian Schroeder, Giuliano Filippini Velazquez, Anna Ossami Saidy, Hristo Boyadzhiev, Tim Sauer, Jan-Henrik Mikesch, Niklas Gebauer, Susanne Ghandili, Paul J. Bröckelmann, Friederike Hildebrand, Veit L. Buecklein, Rebecca Wurm-Kuczera, Ulrich Keller, Georg Lenz, Thomas Pabst, Thomas Melchardt, Claudia Lengerke, Maher Hanoun, Evgenii Shumilov, Ulrike Bacher
Journal: Blood
Blood (2024) 144 (Supplement 1): 3818.
https://doi.org/10.1182/blood-2024-211227
Published: 2024
Journal Articles

Characterization of a Human Bone Marrow-Derived CRISPR/Cas9 Cell Model for Chronic Myeloid Leukemia

Pia Christin Radszuweit, Barbara Mankel, Fulya Korkmaz, Hildegard Keppeler, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2024) 144 (Supplement 1): 1353.
https://doi.org/10.1182/blood-2024-209947
Published: 2024
Journal Articles

Patients with High-Risk Myelodysplastic Neoplasms Do Not Benefit from Remission Induction with Azacitidine Prior to Hematopoietic Cell Transplantation: A Retrospective, Single-Center Analysis with Extended Follow-up

Jan Christian Schröder, Jan Frederic Weller, Philipp Faustmann, Lucas Mix, Christoph Faul, Claudia Lengerke, Wolfgang Andreas Bethge
Journal: Blood
Blood (2023) 142 (Supplement 1): 2231.
https://doi.org/10.1182/blood-2023-174430
Published: 2023
Journal Articles

A Universal CRISPR/Cas9n-Mediated Genome Editing Approach for ELANE -Related Severe Congenital Neutropenia

Masoud Nasri, Malte Ulrich Ritter, Perihan Mir, Benjamin Dannenmann, Masako Monika Kaufmann, Yun Xu, Natalia Borbaran-Bravo, Maksim Klimiankou, Claudia Lengerke, Cornelia Zeidler, Toni Cathomen, Karl Welte, Julia Skokowa
Journal: Blood
Blood (2023) 142 (Supplement 1): 932.
https://doi.org/10.1182/blood-2023-181678
Published: 2023
Journal Articles

Allogeneic Hematopoietic Cell Transplant Recipients Carrying DNMT3A and ASXL1 Mutations More Frequently Develop Severe Graft Versus Host Disease and Arterial Hypertension

Alisha Weiss-Haug, Reka A Haraszti, Britta Merz, Kristina Reuss, Christoph Faul, Wolfgang Andreas Bethge, Frederike Schwartz, Wichard Vogel, Claudia Lengerke
Journal: Blood
Blood (2023) 142 (Supplement 1): 3564.
https://doi.org/10.1182/blood-2023-188752
Published: 2023
Journal Articles

Allogeneic Hematopoietic Stem Cell Transplantation for Adult Metachromatic Leukodystrophy (MLD): A Case Series

Andreas Riedel, Christoph Faul, Kristina Reuss, Peter Lang, Claudia Lengerke, Nadine Weissert, Holger Hengel, Ludger Schoels, Wolfgang Andreas Bethge
Journal: Blood
Blood (2023) 142 (Supplement 1): 7115.
https://doi.org/10.1182/blood-2023-187317
Published: 2023
Journal Articles

Prospective Evaluation of Patient-Reported Outcome up to 10 Years after Allogeneic Stem Cell Transplantation Using FACT-G/BMT and EORTC-QLQ30 Questionnaires

Sina Alexandra Beer, Johanna Blaettel, Kristina Reuss, Jan Christian Schröder, Wichard Vogel, Christoph Faul, Wolfgang Andreas Bethge, Claudia Lengerke
Journal: Blood
Blood (2023) 142 (Supplement 1): 2208.
https://doi.org/10.1182/blood-2023-188833
Published: 2023
Journal Articles

Rational Combinatorial Targeting By Adapter CAR T Cells (AdCAR-T) Prevents Antigen Escape in Acute Myeloid Leukemia (AML)

Daniel Atar, Lara Ruoff, Anna-Sophia Mast, Simon Krost, Moustafa Moustafa-Oglou, Sophia Scheuermann, Beate Kristmann, Maximilian Feige, Aysegül Canak, Katrin Wolsing, Karin Schilbach, Latifa Zekri, Martin Ebinger, Daniel Nixdorf, Marion Subklewe, Johannes Schulte, Claudia Lengerke, Niels Werchau, Joerg Mittelstaet, Peter Lang, Rupert Handgretinger, Patrick Schlegel, Christian Martin Seitz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6834.
https://doi.org/10.1182/blood-2023-185093
Published: 2023
Journal Articles

BRD4 inhibition sensitizes diffuse large B-cell lymphoma cells to ferroptosis

Anja Schmitt, Melanie Grimm, Nina Kreienkamp, Hannah Junge, Jan Labisch, Laurentz Schuhknecht, Caroline Schönfeld, Elsa Görsch, Alessia Tibello, Kerstin Menck, Annalen Bleckmann, Claudia Lengerke, Frank Rosenbauer, Michael Grau, Mattia Zampieri, Klaus Schulze-Osthoff, Pavel Klener, Alexandra Dolnikova, Georg Lenz, Stephan Hailfinger
Journal: Blood
Blood (2023) 142 (13): 1143–1155.
https://doi.org/10.1182/blood.2022019274
Published: 2023
Includes: Supplemental data
Journal Articles

The Role of Mannose Receptor C-Type 2 (MRC2) in Leukemic Stem Cell Maintenance in AML

Marlon Arnone, Elsa Görsch, Simone Pöschel, Anna Stanger, Saskia Rudat, Claudia Lengerke
Journal: Blood
Blood (2022) 140 (Supplement 1): 8706.
https://doi.org/10.1182/blood-2022-156799
Published: 2022
Journal Articles

The Rorɣ/SREBP2 Pathway Is a Master Regulator of Cholesterol Metabolism and Serves As Potential Therapeutic Target in T(4;11) Leukemia

Estelle Erkner, Thomas Hentrich, Rahel Fitzel, Hildegard Keppeler, Fulya Korkmaz, Johan Jeong, Julia Schulze-Hentrich, Claudia Lengerke, Dominik Schneidawind, Corina Schneidawind
Journal: Blood
Blood (2022) 140 (Supplement 1): 2999–3000.
https://doi.org/10.1182/blood-2022-169267
Published: 2022