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Journal Articles

Denosumab for the Treatment of Smoldering Multiple Myeloma: Rates of Osteoporosis and Change in Lowest T-Score after 12 Months of Treatment

Jodi Jacklyn Lipof, Andrea M Baran, Frank Charles Passero, Kaitlyn Burrows, Brea Lipe
Journal: Blood
Blood (2022) 140 (Supplement 1): 12645–12646.
DOI: https://doi.org/10.1182/blood-2022-168297
Published: 2022
Journal Articles

A Phase I Study of Safety, Tolerability and Immunological Effects of SVN53-67/M57-KLH in Patients with Multiple Myeloma Receiving Lenalidomide Maintenance Therapy

Othman Salim Akhtar, Jens Hillengass, Brea Lipe, Sheila A. Figel, Robert A. Fenstermaker, Michael J. Ciesielski, Kelvin P. Lee
Journal: Blood
Blood (2022) 140 (Supplement 1): 10170–10171.
DOI: https://doi.org/10.1182/blood-2022-163597
Published: 2022
Journal Articles

Sea-BCMA Mono- and Combination Therapy in Patients with Relapsed/Refractory Multiple Myeloma: Updated Results of a Phase 1 Study (SGNBCMA-001)

James E. Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Christopher Strouse, Christopher A. Yasenchak, Damian J. Green, Jeremy Sauer, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2022) 140 (Supplement 1): 10160–10162.
DOI: https://doi.org/10.1182/blood-2022-157347
Published: 2022
Journal Articles

Once Weekly Selinexor, Carfilzomib and Dexamethasone (XKd) in Triple Class Refractory Multiple Myeloma

Gary J. Schiller, Sascha A. Tuchman, Natalie Callander, Muhamed Baljevic, Adrianna C Rossi, Rami Kotb, Darrell J White, Nizar J. Bahlis, Heather J. Sutherland, Sumit Madan, Richard Leblanc, Christopher P. Venner, William I. Bensinger, Dane R. Van Domelen, Chris Zhang, Ohad S. Bentur, Brea Lipe
Journal: Blood
Blood (2022) 140 (Supplement 1): 10050–10053.
DOI: https://doi.org/10.1182/blood-2022-158011
Published: 2022
Journal Articles

Updated Interim Results from a Phase 1 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC®) Targeting B Cell Maturation Antigen (BCMA) for Relapsed/Refractory Multiple Myeloma (RRMM)

Al-Ola Abdallah, Andrew J Cowan, Xavier Leleu, Cyrille Touzeau, Brea Lipe, Eva Medvedova, Caitlin Costello, Jens Hillengass, P. Leif Bergsagel, Raya Mawad, Henning Schade, Daniel Morillo Giles, Albert Oriol, Yifah Yaron, Patrick P Ng, Sumit Madan
Journal: Blood
Blood (2022) 140 (Supplement 1): 7284–7285.
DOI: https://doi.org/10.1182/blood-2022-159665
Published: 2022
Journal Articles

Iberdomide (IBER) in Combination with Dexamethasone (DEX) in Relapsed/Refractory Multiple Myeloma (RRMM): Results from the Anti-B-Cell Maturation Antigen (BCMA)-Exposed Cohort of the CC-220-MM-001 Trial

Sagar Lonial, Al-Ola Abdallah, Faiz Anwer, Ashraf Z. Badros, Manisha Bhutani, Abdullah Khan, Brea Lipe, Albert Oriol, Darrell White, Michael Amatangelo, Kexin Jin, Mark Masin, Vi Nguyen, Alpesh Amin, Paulo Maciag, Niels WCJ Van De Donk
Journal: Blood
Blood (2022) 140 (Supplement 1): 4398–4400.
DOI: https://doi.org/10.1182/blood-2022-158180
Published: 2022
Journal Articles

Efficacy and Safety of Selinexor-Containing Regimens in Patients with Multiple Myeloma Previously Treated with Anti-CD38 Monoclonal Antibodies (αCD38 mAb)

Suzanne Lentzsch, Brea Lipe, Sascha A. Tuchman, Nizar J. Bahlis, William I. Bensinger, Michael Sebag, Heather J. Sutherland, Jorge Monge, Cristina J. Gasparetto, Muhamed Baljevic, Natalie S. Callander, Christopher P. Venner, Darrell J. White, Rami Kotb, Christine I. Chen, Gary J. Schiller, Sumit Madan, Richard Leblanc, Andrew DeCastro, Ohad S. Bentur, Jatin J. Shah, Dane R. Van Domelen, Michael G. Kauffman, Sharon Shacham, Noa Biran
Journal: Blood
Blood (2021) 138 (Supplement 1): 1651.
DOI: https://doi.org/10.1182/blood-2021-150232
Published: 2021
Journal Articles

CLR 131 (Iopofosine I-131) Treatment in Triple Class Refractory and Beyond Multiple Myeloma Patients: Preliminary Efficacy and Safety Results from the Phase 2 Clover-1 Trial

Sikander Ailawadhi, Patrick Stiff, Emad Ibrahim, Damian J. Green, Brea Lipe, Elizabeth H. Cull, Natalie S. Callander, John Friend, Jarrod Longcor, Kate Oliver
Journal: Blood
Blood (2021) 138 (Supplement 1): 1652.
DOI: https://doi.org/10.1182/blood-2021-152682
Published: 2021
Journal Articles

An Interim Report on a Phase 1/2 Study of HPN217, a Half-Life Extended Tri-Specific T Cell Activating Construct (TriTAC ® ) Targeting B Cell Maturation Antigen for the Treatment of Relapsed/Refractory Multiple Myeloma

Sumit Madan, Al-Ola Abdallah, Andrew J. Cowan, William I. Bensinger, Jens Hillengass, Xavier Leleu, Eva Medvedova, Caitlin Costello, Brea Lipe, Henning Schade, Rajneesh Nath, Liping Laura Sun
Journal: Blood
Blood (2021) 138 (Supplement 1): 1654.
DOI: https://doi.org/10.1182/blood-2021-148176
Published: 2021
Journal Articles

SEA-BCMA, an Investigational Nonfucosylated Monoclonal Antibody: Ongoing Results of a Phase 1 Study in Patients with Relapsed/Refractory Multiple Myeloma (SGNBCMA-001)

James E Hoffman, Brea Lipe, Jason Melear, Michaela Liedtke, Mark A. Schroeder, Ruben Niesvizky, Michael H. Tomasson, Christopher A. Yasenchak, Damian J. Green, Hong Li, Yinghui Wang, Phoenix Ho, Al-Ola Abdallah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2740.
DOI: https://doi.org/10.1182/blood-2021-146047
Published: 2021
Journal Articles

Selinexor-Based Regimens in Patients with Multiple Myeloma after Prior Anti-B-Cell Maturation Antigen Treatment

Muhamed Baljevic, Cristina Gasparetto, Gary J. Schiller, Sascha A. Tuchman, Natalie S. Callander, Suzanne Lentzsch, Jorge Monge, Rami Kotb, Nizar J. Bahlis, Darrell White, Christine I. Chen, Heather J. Sutherland, Sumit Madan, Richard Leblanc, Michael Sebag, Christopher P. Venner, William I. Bensinger, Noa Biran, Andrew DeCastro, Dane R. Van Domelen, Ohad S. Bentur, Chris Zhang, Jatin J. Shah, Sharon Shacham, Michael G. Kauffman, Brea Lipe
Journal: Blood
Blood (2021) 138 (Supplement 1): 2751.
DOI: https://doi.org/10.1182/blood-2021-150998
Published: 2021
Journal Articles

Once Weekly Oral Selinexor, Pomalidomide, and Dexamethasone in Relapsed Refractory Multiple Myeloma

Darrell J White, Christine I. Chen, Muhamed Baljevic, Sascha A. Tuchman, Nizar J. Bahlis, Gary J. Schiller, Brea Lipe, Rami Kotb, Heather J. Sutherland, William I. Bensinger, Sumit Madan, Michael Sebag, Suzanne Lentzsch, Natalie S. Callander, Noa Biran, Christopher P. Venner, Richard Leblanc, Jorge Monge, Evgeni Chubar, Tamar Tadmor, Noa Lavi, Merav Leiba, Andrew DeCastro, Dane R. Van Domelen, Chris Zhang, Moran Mishal, Ohad S. Bentur, Jatin J. Shah, Sharon Shacham, Michael G. Kauffman, Cristina J. Gasparetto
Journal: Blood
Blood (2021) 138 (Supplement 1): 2748.
DOI: https://doi.org/10.1182/blood-2021-148759
Published: 2021
Journal Articles

Selinexor, Lenalidomide and Dexamethasone (SRd) for Patients with Relapsed/Refractory and Newly Diagnosed Multiple Myeloma

Darrell J White, MD, Richard LeBlanc, MD FRCPC, Muhamed Baljevic, MD, Nizar J. Bahlis, MD, Suzanne Lentzsch, MD PhD, Christopher P. Venner, MD, Cristina Gasparetto, MD, Christine I Chen, MD, Brea Lipe, MD, Sascha A Tuchman, MD, Heather J Sutherland, MD PhD, Rami Kotb, MD, Michael Sebag, MD PhD FRCPC, Natalie S. Callander, MD, William I Bensinger, MD, Adriana C Rossi, MD MSc, Heidi Sheehan, Dane Van Domelen, PhD, Tianjun Zhou, MD PhD, Kai Kazuharu, MD PhD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G Kauffman, MD PhD, Gary J. Schiller, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
DOI: https://doi.org/10.1182/blood-2020-140141
Published: 2020
Journal Articles

Selinexor in Combination with Carfilzomib and Dexamethasone, All Once Weekly (SKd), for Patients with Relapsed/Refractory Multiple Myeloma

Cristina Gasparetto, MD, Brea Lipe, MD, Sascha A Tuchman, MD, Natalie S. Callander, MD, Suzanne Lentzsch, MD PhD, Muhamed Baljevic, MD, Adriana C Rossi, MD MSc, Nizar J. Bahlis, MD, Darrell J White, MD, Christine I Chen, MD, Heather J Sutherland, MD PhD, Rami Kotb, MD, Richard LeBlanc, MD FRCPC, Michael Sebag, MD PhD FRCPC, Christopher P. Venner, MD, William I Bensinger, MD, Heidi Sheehan, Dane Van Domelen, PhD, Kai Kazuharu, MD PhD, Gary J. Schiller, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14–15.
DOI: https://doi.org/10.1182/blood-2020-137183
Published: 2020
Journal Articles

Selinexor in Combination with Pomalidomide and Dexamethasone (SPd) for Treatment of Patients with Relapsed Refractory Multiple Myeloma (RRMM)

Christine I Chen, MD, Nizar J. Bahlis, MD, Cristina Gasparetto, MD, Sascha A Tuchman, MD, Brea Lipe, MD, Muhamed Baljevic, MD, Rami Kotb, MD, Heather J Sutherland, MD PhD, William I Bensinger, MD, Michael Sebag, MD PhD FRCPC, Richard LeBlanc, MD FRCPC, Christopher P. Venner, MD, Gary J. Schiller, MD, Suzanne Lentzsch, MD PhD, Natalie S. Callander, MD, Adriana C Rossi, MD MSc, Heidi Sheehan, Dane Van Domelen, PhD, Kai Kazuharu, MD PhD, Hongwei Wang, MD PhD, Jatin Shah, MD, Sharon Shacham, PhD MBA, Michael G Kauffman, MD PhD, Darrell J White, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 18–19.
DOI: https://doi.org/10.1182/blood-2020-139858
Published: 2020
Journal Articles

A Preliminary Assessment of Heterozygous CFHR3-CFHR1 Deletion As a Permissive Mutation in Carfilzomib-Induced Atypical Hemolytic Uremic Syndrome

Andrew Jay Portuguese, MD, Mark A Fiala, MSW, Tanya M. Wildes, MD MSCI, Ravi Vij, MBBS, Brea Lipe, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 8–9.
DOI: https://doi.org/10.1182/blood-2020-134154
Published: 2020
Journal Articles

Deep and Durable Responses with Selinexor, Daratumumab, and Dexamethasome (SDd) in Patients with Multiple Myeloma (MM) Previously Exposed to Proteasome Inhibitors and Immunomodulatory Drugs: Results of Phase 1b Study of SDd

Cristina J Gasparetto, MD, Suzanne Lentzsch, MD, Gary J. Schiller, MD, William Bensinger, MD, Nizar Bahlis, MD, Heather J. Sutherland, MD PhD, Darrell J. White, MD, Michael Sebag, MD PhD, Rami Kotb, MD, Christopher P. Venner, MD FRCPC, Richard Leblanc, MDFRCPC, Christine I Chen, MD, Aldo Del Col, Jatin J. Shah, MD, Jacqueline Jeha, Jean-Richard Saint-Martin, Michael G. Kauffman, MD PhD, Sharon Shacham, PhD MBA, Joel G. Turner, PhD, Daniel M Sullivan, MD, Brea Lipe, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 599.
DOI: https://doi.org/10.1182/blood-2018-99-117201
Published: 2018
Journal Articles

Selinexor Plus Pomalidomide and Low Dose Dexamethasone (SPd) in Patients with Relapsed or Refractory Multiple Myeloma

Christine I Chen, MD, Heather J. Sutherland, MD PhD, Rami Kotb, MD, Michael Sebag, MD PhD, Darrell J. White, MD, William Bensinger, MD, Cristina J Gasparetto, MD, Richard Leblanc, MDFRCPC, Christopher P. Venner, MD FRCPC, Suzanne Lentzsch, MD, Gary J. Schiller, MD, Brea Lipe, MD, Aldo Del Col, Jatin J. Shah, MD, Jacqueline Jeha, Jean-Richard Saint-Martin, Michael G. Kauffman, MD PhD, Sharon Shacham, PhD MBA, Nizar Bahlis, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1993.
DOI: https://doi.org/10.1182/blood-2018-99-117349
Published: 2018
Journal Articles

Dwjm-Adherence Induces Chemotherapy Resistance in Primary Acute Myeloid Leukemia By Altering Leukemia Cell Metabolism

Brea Lipe, MD, Thomas Conley, Hani Awad, PhD, Jason H. Mendler, MD PhD, Jason R Myers, MS, John M Ashton, PhD, Michael W. Becker, MD, Omar S. Aljitawi, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3953.
DOI: https://doi.org/10.1182/blood-2018-99-117476
Published: 2018
Journal Articles

Selinexor in Combination with Weekly Low Dose Bortezomib and Dexamethasone (SVd) Induces a High Response Rate with Durable Responses in Patients with Refractory Multiple Myeloma (MM)

Nizar J. Bahlis, MD, Heather Sutherland, MD, Darrell J White, MD, Michael Sebag, MD PhD, Suzanne Lentzsch, MD PhD, Rami Kotb, MD, Christopher P. Venner, MD, Cristina J. Gasparetto, MD, Gary J Schiller, MD, Richard LeBlanc, MDFRCPC, William Bensinger, MD, Brea Lipe, MD, Aldo Del Col, BSPharm, MBA, Michael G. Kauffman, MD PhD, Sharon Shacham, PhD MBA, Jacqueline Jeha, Jean-Richard Saint-Martin, BS, Jatin Shah, MD, Christine I Chen, MD FRCP(C)
Journal: Blood
Blood (2017) 130 (Supplement 1): 3135.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.3135.3135
Published: 2017