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Binje Vick
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Journal Articles

Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR

Dana Stenger, Tanja A. Stief, Theresa Kaeuferle, Semjon Willier, Felicitas Rataj, Kilian Schober, Binje Vick, Ramin Lotfi, Beate Wagner, Thomas G. P. Grünewald, Sebastian Kobold, Dirk H. Busch, Irmela Jeremias, Franziska Blaeschke, Tobias Feuchtinger
Journal: Blood
Blood (2020) 136 (12): 1407–1418.
DOI: https://doi.org/10.1182/blood.2020005185
Published: 2020
Includes: Supplemental data
Journal Articles

Single Cell Clones Derived from a Patient's AML Xenograft Display Genetic and Functional Heterogeneity

Christina Maria Zeller, MSc, Daniel Richter, MSc, Binje Vick, PhD, Tobias Herold, MD, Johannes Bagnoli, Maja Rothenberg-Thurley, PhD, Klaus H. Metzeler, MD, Karsten Spiekermann, MD, Wolfgang Enard, PhD, Irmela Jeremias, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1450.
DOI: https://doi.org/10.1182/blood-2019-127867
Published: 2019
Journal Articles

Evaluation of a Bifunctional Sirpα-CD123 Fusion Antibody for the Elimination of Acute Myeloid Leukemia Stem Cells

Siret Tahk, Saskia Schmitt, Christian Peter Augsberger, Binje Vick, PhD, Laia Pascual Ponce, PhD, Irmela Jeremias, MD PhD, Georg Wittmann, MD, Nadja Fenn, PhD, Marion Subklewe, MD, Karl-Peter Hopfner, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2544.
DOI: https://doi.org/10.1182/blood-2019-128145
Published: 2019
Journal Articles

Hepatic leukemia factor is a novel leukemic stem cell regulator in DNMT3A, NPM1, and FLT3-ITD triple-mutated AML

Swati Garg, Armando Reyes-Palomares, Lixiazi He, Anne Bergeron, Vincent-Philippe Lavallée, Sébastien Lemieux, Patrick Gendron, Christian Rohde, Jianglong Xia, Prarabdha Jagdhane, Carsten Müller-Tidow, Daniel B. Lipka, Suzan Imren, R. Keith Humphries, Claudia Waskow, Binje Vick, Irmela Jeremias, Guillaume Richard-Carpentier, Josée Hébert, Guy Sauvageau, Judith B. Zaugg, Frédéric Barabé, Caroline Pabst
Journal: Blood
Blood (2019) 134 (3): 263–276.
DOI: https://doi.org/10.1182/blood.2018862383
Published: 2019
Includes: Supplemental data
Journal Articles

Long-Term Dormant Cells in Acute Myeloid Leukemia Patient-Derived Xenografts Display Reversible Treatment Resistance, but Are Not Enriched for Leukemia-Initiating Cells

Sarah Ebinger, MSc, Binje Vick, PhD, Karsten Spiekermann, MD, Irmela Jeremias, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1518.
DOI: https://doi.org/10.1182/blood-2018-99-109731
Published: 2018
Journal Articles

Loss of KDM6A Confers Drug Resistance in Acute Myeloid Leukemia

Sophie M. Stief, M.Sc., Anna-Li Hanneforth, Raphael Mattes, Sabrina Weser, M.Sc., Binje Vick, PhD, Michael D. Bartoschek, M.Sc., Helena Domínguez Moreno, M.Sc., Wen-Hsin Liu, PhD, Bianka Ksienzyk, Maja Rothenberg-Thurley, PhD, Hilmar Quentmeier, PhD, Wolfgang Hiddemann, Klaus H. Metzeler, MD, Gunnar Schotta, PhD, Sebastian Bultmann, PhD, Irmela Jeremias, MD PhD, Heinrich Leonhardt, PhD, Karsten Spiekermann, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3935.
DOI: https://doi.org/10.1182/blood-2018-99-114959
Published: 2018
Journal Articles

Therapy‐Induced Senescence Is a Predictor of Treatment Outcome in Acute Myeloid Leukemia

Martin Schönlein, J. Henry M. Däbritz, Dorothy Ngo-Yin Fan, Jana Ihlow, Rolf Schwarzer, Binje Vick, Karsten Spiekermann, Thomas Burmeister, Jörg Westermann, Irmela Jeremias, Clemens A. Schmitt
Journal: Blood
Blood (2017) 130 (Supplement 1): 1393.
DOI: https://doi.org/10.1182/blood.V130.Suppl_1.1393.1393
Published: 2017
Journal Articles

Peptide-Receptor Radiotherapy with CXCR4-Targeting Pentixather Reduces Leukemia Burden in Acute Leukemia PDX and Patients

Stefan Habringer, MD, Peter Herhaus, Margret Schottelius, PhD, Constantin Lapa, MD, Rouzanna Istvanffy, PhD, Katharina Götze, Katja Steiger, DVM, Binje Vick, PhD, Christian Peschel, MD, Robert Oostendorp, PhD, Irmela Jeremias, MD, Hans-Jürgen Wester, PhD, Goetz Ulrich Grigoleit, MD, Ulrich Keller, MD
Journal: Blood
Blood (2016) 128 (22): 4055.
DOI: https://doi.org/10.1182/blood.V128.22.4055.4055
Published: 2016
Journal Articles

Targeting the ER-Mitochondrial Interface of Cell Death Sensitizes Leukemia Cells Towards Cytostatics

Fabian Koczian, Jan Vomacka, Binje Vick, PhD, Britta F Hettich, Uli Kazmaier, Stephan A Sieber, Irmela Jeremias, MD, Angelika M Vollmar, Simone Braig
Journal: Blood
Blood (2016) 128 (22): 2319.
DOI: https://doi.org/10.1182/blood.V128.22.2319.2319
Published: 2016
Journal Articles

Tyrosin Kinase Inhibition Restores the Membrane Localization of FLT3-ITD

Katrin S. Reiter, Harald Polzer, PhD, Christina Krupka, Binje Vick, PhD, Andreas Maiser, Marion S. Subklewe, MD, Irmela Jeremias, MD, Heinrich Leonhardt, PhD, Karsten Spiekermann, MD, Philipp A. Greif, MD
Journal: Blood
Blood (2015) 126 (23): 1274.
DOI: https://doi.org/10.1182/blood.V126.23.1274.1274
Published: 2015
Journal Articles

Azacitidine in Combination with the Selective FLT3 Kinase Inhibitor Crenolanib Effectively Disrupts Stromal Protection of CD34+ Leukemia-Initiating Cells (LIC) in FLT3-ITD+ Acute Myeloid Leukemia (AML)

Anne-Kathrin Garz, M.Sc., Stefan Habringer, Saskia Wolf, Binje Vick, PhD, Marie-Theresa Weickert, M.Sc., Irmela Jeremias, MD, Karsten Spiekermann, MD, Christian Peschel, MD, Robert A.J. Oostendorp, PhD, Ulrich Keller, Katharina S. Götze, MD
Journal: Blood
Blood (2015) 126 (23): 676.
DOI: https://doi.org/10.1182/blood.V126.23.676.676
Published: 2015
Journal Articles

Bioluminescence in Vivo Imaging Improves the Model of Individual Patients' AML Cells Growing in Mice for Sensitive and Reliable Preclinical Treatment Trials on Various Genetic Subgroups

Irmela Jeremias, MD, Binje Vick, Dr., Maya Rothenberg, Nadine Sandhöfer, MSc, Michela Carlet, PhD, Christina Krupka, Andreas Trumpp, PhD, Selim Corbacioglu, MD, Martin Ebinger, MD, Maya Caroline Andre, MD, Wolfgang Hiddemann, MD, Stephanie Schneider, PhD, Marion Subklewe, MD, Klaus H Metzeler, MD, Karsten Spiekermann, MD
Journal: Blood
Blood (2014) 124 (21): 2323.
DOI: https://doi.org/10.1182/blood.V124.21.2323.2323
Published: 2014
Journal Articles

Genetic Profiling By Targeted, Deep Resequencing Confirms That a Murine Xenograft Model Of Acute Myeloid Leukemia (AML) Recapitulates The Mutational Landscape Of The Human Disease and Provides Evidence For Clonal Heterogeneity and Clonal Evolution

Maja Rothenberg-Thurley, Dr., Binje Vick, Dr., Stephanie Schneider, PhD, Bianka Ksienzyk, Philipp A Greif, MD, Michael Fiegl, MD, Marion Subklewe, MD, Wolfgang Hiddemann, M.D., Karsten Spiekermann, MD, Irmela Jeremias, MD, Klaus H. Metzeler, MD
Journal: Blood
Blood (2013) 122 (21): 49.
DOI: https://doi.org/10.1182/blood.V122.21.49.49
Published: 2013
Journal Articles

The Role of Mcl-1 Expression and Phosphorlyation in Resistance to Chemotherapy and Kinase Inhibitors in FLT3-ITD-Positive Acute Myeloid Leukemia (AML)

Florian H Heidel, MD, Henning Schulze-Bergkamen, MD, Binje Vick, Daniel B Lipka, MD, Fian K Mirea, Toni Urbanik, Joseph T Opferman, PhD, Thomas Fischer, MD
Journal: Blood
Blood (2008) 112 (11): 220.
DOI: https://doi.org/10.1182/blood.V112.11.220.220
Published: 2008