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Journal Articles

Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey

Bharat B. Aggarwal, Subash C. Gupta, Ji Hye Kim

Blood (2012) 119 (3): 651–665.

https://doi.org/10.1182/blood-2011-04-325225

Published: 2012

Journal Articles

Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB–regulated gene products and potentiation of apoptosis in leukemia cells

Kuzhuvelil B. Harikumar, Ajaikumar B. Kunnumakkara, Kwang S. Ahn, Preetha Anand, Sunil Krishnan, Sushovan Guha, Bharat B. Aggarwal

Blood (2009) 113 (9): 2003–2013.

https://doi.org/10.1182/blood-2008-04-151944

Published: 2009

Includes: Supplemental data

Journal Articles

Anacardic acid (6-nonadecyl salicylic acid), an inhibitor of histone acetyltransferase, suppresses expression of nuclear factor-κB–regulated gene products involved in cell survival, proliferation, invasion, and inflammation through inhibition of the inhibitory subunit of nuclear factor-κBα kinase, leading to potentiation of apoptosis

Bokyung Sung, Manoj K. Pandey, Kwang Seok Ahn, Tingfang Yi, Madan M. Chaturvedi, Mingyao Liu, Bharat B. Aggarwal

Blood (2008) 111 (10): 4880–4891.

https://doi.org/10.1182/blood-2007-10-117994

Published: 2008

Journal Articles

Curcumin Downregulates NF-kB and Related Genes in Patients with Multiple Myeloma: Results of a Phase I/II Study.

Saroj Vadhan-Raj, MD, Donna M. Weber, MD, BS, Michael Wang, MD, MS, Sergio A. Giralt, MD, Sheeba K. Thomas, MD, Raymond Alexanian, MD, Xiao Zhou, MD, Priya Patel, BS, Carlos E. Bueso-Ramos, MD, PHD, Robert A. Newman, PHD, MS, Bharat B. Aggarwal, PHD, MS

Blood (2007) 110 (11): 1177.

https://doi.org/10.1182/blood.V110.11.1177.1177

Published: 2007

Journal Articles

Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway

Manoj K. Pandey, Bokyung Sung, Kwang Seok Ahn, Ajaikumar B. Kunnumakkara, Madan M. Chaturvedi, Bharat B. Aggarwal

Blood (2007) 110 (10): 3517–3525.

https://doi.org/10.1182/blood-2007-03-079616

Published: 2007

Journal Articles

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-κB–regulated gene products

Kwang Seok Ahn, Gautam Sethi, Ta-Hsiang Chao, Saskia T. C. Neuteboom, Madan M. Chaturvedi, Michael A. Palladino, Anas Younes, Bharat B. Aggarwal

Blood (2007) 110 (7): 2286–2295.

https://doi.org/10.1182/blood-2007-04-084996

Published: 2007

Journal Articles

Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-κB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis

Ajaikumar B. Kunnumakkara, Asha S. Nair, Kwang Seok Ahn, Manoj K. Pandey, Zhengfang Yi, Mingyao Liu, Bharat B. Aggarwal

Blood (2007) 109 (12): 5112–5121.

https://doi.org/10.1182/blood-2007-01-067256

Published: 2007

Journal Articles

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

Anjana Bhardwaj, Gautam Sethi, Saroj Vadhan-Raj,, Carlos Bueso-Ramos, Yasunari Takada, Upasna Gaur, Asha S. Nair, Shishir Shishodia, Bharat B. Aggarwal

Blood (2006) 109 (6): 2293–2302.

https://doi.org/10.1182/blood-2006-02-003988

Published: 2006

Journal Articles

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB–regulated gene products and TAK1-mediated NF-κB activation

Gautam Sethi, Kwang Seok Ahn, Manoj K. Pandey, Bharat B. Aggarwal

Blood (2006) 109 (7): 2727–2735.

https://doi.org/10.1182/blood-2006-10-050807

Published: 2006

Journal Articles

Indole-3-carbinol suppresses NF-κB and IκBα kinase activation, causing inhibition of expression of NF-κB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells

Yasunari Takada, Michael Andreeff, Bharat B. Aggarwal

Blood (2005) 106 (2): 641–649.

https://doi.org/10.1182/blood-2004-12-4589

Published: 2005

Journal Articles

Evidence that genetic deletion of the TNF receptor p60 or p80 in macrophages modulates RANKL-induced signaling

Yasunari Takada, Bharat B. Aggarwal

Blood (2004) 104 (13): 4113–4121.

https://doi.org/10.1182/blood-2004-04-1607

Published: 2004

Journal Articles

Nuclear factor–κB and STAT3 are constitutively active in CD138 + cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis

Alok C. Bharti, Shishir Shishodia, James M. Reuben, Donna Weber, Raymond Alexanian, Saroj Raj-Vadhan, Zeev Estrov, Moshe Talpaz, Bharat B. Aggarwal

Blood (2004) 103 (8): 3175–3184.

https://doi.org/10.1182/blood-2003-06-2151

Published: 2004

Journal Articles

Resveratrol blocks interleukin-1β–induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

Zeev Estrov, Shishir Shishodia, Stefan Faderl, David Harris, Quin Van, Hagop M. Kantarjian, Moshe Talpaz, Bharat B. Aggarwal

Blood (2003) 102 (3): 987–995.

https://doi.org/10.1182/blood-2002-11-3550

Published: 2003

Journal Articles

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

Alok C. Bharti, Nicholas Donato, Sujay Singh, Bharat B. Aggarwal

Blood (2003) 101 (3): 1053–1062.

https://doi.org/10.1182/blood-2002-05-1320

Published: 2003

Journal Articles

Functional expression of receptor activator of nuclear factor κB in Hodgkin disease cell lines

Paolo Fiumara, Virginia Snell, Yang Li, Asok Mukhopadhyay, Mamoun Younes, Ann Marie Gillenwater, Fernando Cabanillas, Bharat B. Aggarwal, Anas Younes

Blood (2001) 98 (9): 2784–2790.

https://doi.org/10.1182/blood.V98.9.2784

Published: 2001

Journal Articles

Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells

Zeev Estrov, Sunil K. Manna, David Harris, Quin Van, Elihu H. Estey, Hagop M. Kantarjian, Moshe Talpaz, Bharat B. Aggarwal

Blood (1999) 94 (8): 2844–2853.

https://doi.org/10.1182/blood.V94.8.2844.420k43_2844_2853

Published: 1999

Journal Articles

Human Immunodeficiency Virus-1–Tat Protein Induces the Cell Surface Expression of Endothelial Leukocyte Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and Intercellular Adhesion Molecule-1 in Human Endothelial Cells

Subhash Dhawan, Raj K. Puri, Ashok Kumar, Helen Duplan, Jean-Michel Masson, Bharat B. Aggarwal

Blood (1997) 90 (4): 1535–1544.

https://doi.org/10.1182/blood.V90.4.1535

Published: 1997

NARROW

Historical perspectives on tumor necrosis factor and its superfamily: 25 years later, a golden journey

Modification of the cysteine residues in IκBα kinase and NF-κB (p65) by xanthohumol leads to suppression of NF-κB–regulated gene products and potentiation of apoptosis in leukemia cells

Curcumin Downregulates NF-kB and Related Genes in Patients with Multiple Myeloma: Results of a Phase I/II Study.

Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway

Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-κB–regulated gene products

Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-κB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-κB–regulated antiapoptotic and cell survival gene products in human multiple myeloma cells

Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB–regulated gene products and TAK1-mediated NF-κB activation

Indole-3-carbinol suppresses NF-κB and IκBα kinase activation, causing inhibition of expression of NF-κB-regulated antiapoptotic and metastatic gene products and enhancement of apoptosis in myeloid and leukemia cells

Evidence that genetic deletion of the TNF receptor p60 or p80 in macrophages modulates RANKL-induced signaling

Nuclear factor–κB and STAT3 are constitutively active in CD138 + cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis

Resveratrol blocks interleukin-1β–induced activation of the nuclear transcription factor NF-κB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis

Functional expression of receptor activator of nuclear factor κB in Hodgkin disease cell lines

Phenylarsine Oxide Blocks Interleukin-1β–Induced Activation of the Nuclear Transcription Factor NF-κB, Inhibits Proliferation, and Induces Apoptosis of Acute Myelogenous Leukemia Cells

Human Immunodeficiency Virus-1–Tat Protein Induces the Cell Surface Expression of Endothelial Leukocyte Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and Intercellular Adhesion Molecule-1 in Human Endothelial Cells

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American Society of Hematology

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ASH Publications

American Society of Hematology

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