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Journal Articles

PI3Kinase Inactivation through Combined Loss of Catalytic Subunits p110α, p110β and p110δ Derails Hematopoietic Homeostasis

Lakshmi Reddy Palam, PhD, Raghuveer Mali, PhD, Baskar Ramdas, PhD, Bart Vanhaesebroeck, PhD, Reuben Kapur, PhD

Blood (2017) 130 (Supplement 1): 3754.

https://doi.org/10.1182/blood.V130.Suppl_1.3754.3754

Published: 2017

Journal Articles

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth

Colin Valet, Marie Levade, Gaëtan Chicanne, Benoit Bilanges, Cendrine Cabou, Julien Viaud, Marie-Pierre Gratacap, Frédérique Gaits-Iacovoni, Bart Vanhaesebroeck, Bernard Payrastre, Sonia Severin

Blood (2017) 130 (18): 2032–2042.

https://doi.org/10.1182/blood-2017-04-781641

Published: 2017

Includes: Multimedia, Supplemental data

Journal Articles

Essential role of class II PI3K-C2α in platelet membrane morphology

Colin Valet, Gaëtan Chicanne, Childerick Severac, Claire Chaussade, Maria A. Whitehead, Cendrine Cabou, Marie-Pierre Gratacap, Frederique Gaits-Iacovoni, Bart Vanhaesebroeck, Bernard Payrastre, Sonia Severin

Blood (2015) 126 (9): 1128–1137.

https://doi.org/10.1182/blood-2015-03-636670

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate

Pierre-Alexandre Laurent, Sonia Séverin, Béatrice Hechler, Bart Vanhaesebroeck, Bernard Payrastre, Marie-Pierre Gratacap

Blood (2015) 125 (5): 881–888.

https://doi.org/10.1182/blood-2014-07-588335

Published: 2015

Includes: Multimedia, Supplemental data

Journal Articles

Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy

George Haddad, Pavel Zhabyeyev, Maikel Farhan, Lin Fu Zhu, Zamaneh Kassiri, David C. Rayner, Bart Vanhaesebroeck, Gavin Y. Oudit, Allan G. Murray

Blood (2014) 124 (13): 2142–2149.

https://doi.org/10.1182/blood-2014-02-557975

Published: 2014

Includes: Supplemental data

Journal Articles

PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML

Charles B Goodwin, Xing Jun Li, Raghuveer S. Mali, Gordon Chan, Michelle Kang, Ziyue Liu, Bart Vanhaesebroeck, Benjamin G. Neel, Mignon L. Loh, Brian J. Lannutti, Reuben Kapur, Rebecca J. Chan

Blood (2014) 123 (18): 2838–2842.

https://doi.org/10.1182/blood-2013-10-535104

Published: 2014

Journal Articles

Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

Valérie Martin, Julie Guillermet-Guibert, Gaétan Chicanne, Cendrine Cabou, Martine Jandrot-Perrus, Monique Plantavid, Bart Vanhaesebroeck, Bernard Payrastre, Marie-Pierre Gratacap

Blood (2010) 115 (10): 2008–2013.

https://doi.org/10.1182/blood-2009-04-217224

Published: 2010

Includes: Supplemental data

Journal Articles

CCL21 mediates CD4 + T-cell costimulation via a DOCK2/Rac-dependent pathway

Kathrin Gollmer, François Asperti-Boursin, Yoshihiko Tanaka, Klaus Okkenhaug, Bart Vanhaesebroeck, Jeffrey R. Peterson, Yoshinori Fukui, Emmanuel Donnadieu, Jens V. Stein

Blood (2009) 114 (3): 580–588.

https://doi.org/10.1182/blood-2009-01-200923

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation

Hong Ji, Felix Rintelen, Caroline Waltzinger, Dominique Bertschy Meier, Antonio Bilancio, Wayne Pearce, Emilio Hirsch, Matthias P. Wymann, Thomas Rückle, Montserrat Camps, Bart Vanhaesebroeck, Klaus Okkenhaug, Christian Rommel

Blood (2007) 110 (8): 2940–2947.

https://doi.org/10.1182/blood-2007-04-086751

Published: 2007

Includes: Supplemental data

Journal Articles

The Pten/PI3K pathway governs the homeostasis of Vα14 i NKT cells

Hiroyuki Kishimoto, Toshiaki Ohteki, Nobuyuki Yajima, Koichi Kawahara, Miyuki Natsui, Satoru Kawarasaki, Koichi Hamada, Yasuo Horie, Yoshiaki Kubo, Seiji Arase, Masaru Taniguchi, Bart Vanhaesebroeck, Tak Wah Mak, Toru Nakano, Shigeo Koyasu, Takehiko Sasaki, Akira Suzuki

Blood (2006) 109 (8): 3316–3324.

https://doi.org/10.1182/blood-2006-07-038059

Published: 2006

Includes: Supplemental data

Journal Articles

Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110δ function in B cells

Antonio Bilancio, Klaus Okkenhaug, Montserrat Camps, Juliet L. Emery, Thomas Ruckle, Christian Rommel, Bart Vanhaesebroeck

Blood (2006) 107 (2): 642–650.

https://doi.org/10.1182/blood-2005-07-3041

Published: 2006

Journal Articles

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

Alison M. Condliffe, Keith Davidson, Karen E. Anderson, Chris D. Ellson, Tom Crabbe, Klaus Okkenhaug, Bart Vanhaesebroeck, Martin Turner, Louise Webb, Matthias P. Wymann, Emilio Hirsch, Thomas Ruckle, Montserrat Camps, Christian Rommel, Shaun P. Jackson, Edwin R. Chilvers, Len R. Stephens, Phillip T. Hawkins

Blood (2005) 106 (4): 1432–1440.

https://doi.org/10.1182/blood-2005-03-0944

Published: 2005

Includes: Supplemental data

Journal Articles

Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

Blood (2005) 106 (3): 1063–1066.

https://doi.org/10.1182/blood-2004-08-3225

Published: 2005

NARROW

PI3Kinase Inactivation through Combined Loss of Catalytic Subunits p110α, p110β and p110δ Derails Hematopoietic Homeostasis

A dual role for the class III PI3K, Vps34, in platelet production and thrombus growth

Essential role of class II PI3K-C2α in platelet membrane morphology

Platelet PI3Kβ and GSK3 regulate thrombus stability at a high shear rate

Phosphoinositide 3-kinase β mediates microvascular endothelial repair of thrombotic microangiopathy

PI3K p110δ uniquely promotes gain-of-function Shp2-induced GM-CSF hypersensitivity in a model of JMML

Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo

CCL21 mediates CD4 + T-cell costimulation via a DOCK2/Rac-dependent pathway

Inactivation of PI3Kγ and PI3Kδ distorts T-cell development and causes multiple organ inflammation

The Pten/PI3K pathway governs the homeostasis of Vα14 i NKT cells

Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110δ function in B cells

Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils

Essential role for the p110δ isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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