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Journal Articles

Genomic Drivers of Large B-Cell Lymphoma Resistance to CD19 CAR-T Therapy

Michael D. Jain, Bachisio Ziccheddu, Caroline A. Coughlin, Rawan Faramand, Anthony J. Griswold, Kayla M Reid, Ola Landgren, Frederick L. Locke, Francesco Maura, Marco L. Davila, Jonathan H. Schatz
Journal: Blood
Blood (2021) 138 (Supplement 1): 42.
DOI: https://doi.org/10.1182/blood-2021-148605
Published: 2021
Journal Articles

Molecular Evolution of Classical Hodgkin Lymphoma Revealed Though Whole Genome Sequencing of Hodgkin and Reed-Sternberg Cells

Francesco Maura, Marcin Imielinski, Jenny Z Xiang, Bhavneet Binder, Kenneth Eng, Manik Uppal, Feng He, Wei Zhang, Qi Gao, Sunita I. Park, Matthew J. Oberley, Elizabeth Ruckdeschel, Megan S. Lim, Gerald Wertheim, Matthew J. Barth, Terzah M. Horton, Bachisio Ziccheddu, Federico Abascal, Kylee H Maclachlan, Venkata D Yellapantula, Ola Landgren, Craig H. Moskowitz, Ethel Cesarman, Mikhail Roshal, Olivier Elemento, Lisa Giulino Roth
Journal: Blood
Blood (2021) 138 (Supplement 1): 805.
DOI: https://doi.org/10.1182/blood-2021-148663
Published: 2021
Journal Articles

The Genomic Landscape of Waldenström Macroglobulinemia Reveals Sustained Germinal Center Activity and Late-Developing Copy Number Aberrations

Kylee H Maclachlan, Tina Bagratuni, Efstathios Kastritis, Bachisio Ziccheddu, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Benjamin Diamond, Monika Chojnacka, Arjun Raj, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Andriy Derkach, Elli Papaemmanuil, Ahmet Dogan, Alexander Lesokhin, Ola Landgren, M. Lia Palomba, Francesco Maura, Meletios-Athanasios Dimopoulos
Journal: Blood
Blood (2021) 138 (Supplement 1): 2394.
DOI: https://doi.org/10.1182/blood-2021-148095
Published: 2021
Journal Articles

Chemotherapy-Related Mutational Signatures Reveal the Origins of Therapy-Related Myeloid Neoplasms

Benjamin Diamond, Bachisio Ziccheddu, Eileen M Boyle, Kylee H Maclachlan, Juan Arango Ossa, Justin Taylor, Justin Watts, Sydney X. Lu, Venkata D Yellapantula, Christopher Famulare, Monika Chojnacka, Arjun Raj Rajanna, Emilia Mason, David G. Coffey, James E. Hoffman, Dickran Kazandjian, Terrence J Bradley, Menglei Zhu, Niccolo Bolli, Elli Papaemmanuil, Kelly L. Bolton, Michael Scordo, Oscar B Lahoud, Eytan M. Stein, Craig S. Sauter, Hani Hassoun, Sham Mailankody, Neha Korde, Malin Hultcrantz, Urvi A Shah, Gunjan L Shah, Jae H Park, Heather J Landau, Karuna Ganesh, Mikkael A. Sekeres, Stephen Nimer, David J. Chung, Caleb Ho, Mikhail Roshal, Alexander Lesokhin, Gareth J. Morgan, Ola Landgren, Francesco Maura
Journal: Blood
Blood (2021) 138 (Supplement 1): 3271.
DOI: https://doi.org/10.1182/blood-2021-145927
Published: 2021
Journal Articles

Genomic and Immune Signatures Predict Sustained MRD Negativity in Newly Diagnosed Multiple Myeloma Patients Treated with Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone (D-KRd)

Francesco Maura, Eileen M Boyle, Benjamin Diamond, Patrick Blaney, Hussein Ghamlouch, Bachisio Ziccheddu, Yubao Wang, Kylee H Maclachlan, James E. Hoffman, Hani Hassoun, Sham Mailankody, Urvi A Shah, Carlyn Tan, Malin Hultcrantz, Michael Scordo, Dickran Kazandjian, Gunjan L Shah, Heather J Landau, David J. Chung, Sergio Giralt, Benedetto Bruno, Yanming Zhang, Arnaldo A Arbini, Ahmet Dogan, Alexander Lesokhin, Faith E Davies, Neha Korde, Gareth J Morgan, Ola Landgren
Journal: Blood
Blood (2021) 138 (Supplement 1): 325.
DOI: https://doi.org/10.1182/blood-2021-149112
Published: 2021
Journal Articles

Specific targeting of the KRAS mutational landscape in myeloma as a tool to unveil the elicited antitumor activity

Antonio Sacco, Cinzia Federico, Katia Todoerti, Bachisio Ziccheddu, Valentina Palermo, Arianna Giacomini, Cosetta Ravelli, Federica Maccarinelli, Giada Bianchi, Angelo Belotti, Rossella Ribolla, Vanessa Favasuli, Alexey S. Revenko, A. Robert Macleod, Brandon Willis, Hongbo Cai, Joana Hauser, Claire Rooney, Sophie E. Willis, Philip Lloyd Martin, Anna Staniszewska, Helen Ambrose, Lyndsey Hanson, Chiara Cattaneo, Alessandra Tucci, Giuseppe Rossi, Roberto Ronca, Antonino Neri, Stefania Mitola, Niccolò Bolli, Marco Presta, Michele Moschetta, Sarah Ross, Aldo M. Roccaro
Journal: Blood
Blood (2021) 138 (18): 1705–1720.
DOI: https://doi.org/10.1182/blood.2020010572
Published: 2021
Includes: Supplemental data
Journal Articles

Revealing Transcriptome Deregulation upon Genomic Complexity in Multiple Myeloma

Matteo Claudio Da Via', MD, Bachisio Ziccheddu, Matteo Dugo, Marta Lionetti, PhD, Katia Todoerti, PhD, Mattia D'Agostino, MD, Antonino Neri, MD, Luca Baldini, MD PhD, Paolo Corradini, Francesco Maura, MD, Niccolo Bolli, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
DOI: https://doi.org/10.1182/blood-2020-136211
Published: 2020
Journal Articles

Timing the Initiation of Multiple Myeloma

Francesco Maura, MD, Even H Rustad, MD, Niccolò Bolli, MD PhD, Venkata Yellapantula, PhD, Daniel A. Leongamornlert, PhD, Ferran Nadeu, BSc, MSc, Nicos Angelopoulos, PhD, Kevin J Dawson, Thomas J Mitchell, Rob Osborne, Bachisio Ziccheddu, PhD, Cristiana Carniti, PhD, Vittorio Montefusco, Paolo Corradini, Kenneth C. Anderson, MD, Philippe Moreau, MD, Elli Papaemmanuil, PhD, Ludmil Alexandrov, Xose S Puente, Elias Campo, Reiner Siebert, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD, Peter J Campbell, Ola Landgren, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 573.
DOI: https://doi.org/10.1182/blood-2019-124357
Published: 2019
Journal Articles

Specific Targeting of KRAS Using a Novel High-Affinity KRAS Antisense Oligonucleotide in Multiple Myeloma

Antonio Sacco, RN, Cinzia Federico, PhD, Katia Todoerti, PhD, Bachisio Ziccheddu, PhD, Arianna Giacomini, PhD, Cosetta Ravelli, PhD, Federica Maccarinelli, PhD, Giada Bianchi, MD, Angelo Belotti, Rossella Ribolla, MD, Vanessa Favasuli, Alexey Revenko, PhD, A. Robert MacLeod, PhD, Brandon Willis, PhD, Hongoo Cai, PhD, Joana Hauser, RN, Claire Rooney, PhD, Helen Ambrose, PhD, Anna Staniszewska, PhD, Lyndsey Hanson, PhD, Giuseppe Rossi, Roberto Ronca, PhD, Antonino Neri, MD, Stefania Mitola, PhD, Niccolò Bolli, MD PhD, Marco Presta, PhD, Michele Moschetta, MD PhD, Sarah Ross, PhD, Aldo M. Roccaro, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3104.
DOI: https://doi.org/10.1182/blood-2019-124391
Published: 2019
Journal Articles

The Genomic and Transcriptomic Landscape of Double-Refractory Multiple Myeloma

Bachisio Ziccheddu, PhD, Giulia Biancon, Chiara De Philippis, MD, Filippo Bagnoli, MD, Francesco Maura, MD, Matteo Dugo, Andrea Devecchi, Loris De Cecco, Marialuisa Sensi, Carolina Terragna, Marina Martello, Tina Bagratuni, PhD, Eftathios Kastritis, Meletios A. Dimopoulos, MD, Michele Cavo, Cristiana Carniti, PhD, Vittorio Montefusco, Paolo Corradini, Niccolo Bolli, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3056.
DOI: https://doi.org/10.1182/blood-2019-122197
Published: 2019