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Athina Giannoudis
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Journal Articles

The hOCT1 SNPs M420del and M408V alter imatinib uptake and M420del modifies clinical outcome in imatinib-treated chronic myeloid leukemia

Athina Giannoudis, Lihui Wang, Andrea L. Jorgensen, George Xinarianos, Andrea Davies, Sudeep Pushpakom, Triantafilos Liloglou, Jieying-Eunice Zhang, Gemma Austin, Tessa L. Holyoake, Letizia Foroni, Panagiotis D. Kottaridis, Martin C. Müller, Munir Pirmohamed, Richard E. Clark
Journal: Blood
Blood (2013) 121 (4): 628–637.
https://doi.org/10.1182/blood-2012-01-405035
Published: 2013
Includes: Supplemental data
Journal Articles

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

Clinical Trials & Observations
Claire M. Lucas, Robert J. Harris, Athina Giannoudis, Mhairi Copland, Joseph R. Slupsky, Richard E. Clark
Journal: Blood
Blood (2011) 117 (24): 6660–6668.
https://doi.org/10.1182/blood-2010-08-304477
Published: 2011
Includes: Supplemental data
Journal Articles

Nilotinib concentration in Cell Lines and CML CD34+ Cells Is Not Mediated by Active Uptake or Efflux by Major Drug Transporters

Joanne Mountford, PhD, Andrea Davies, Niove E Jordanides, Athina Giannoudis, Claire M Lucas, Sophia Hatziieremia, Robert J Harris, Heather G Jorgensen, Munir Pirmohamed, Tessa L Holyoake, Richard E Clark
Journal: Blood
Blood (2008) 112 (11): 3205.
https://doi.org/10.1182/blood.V112.11.3205.3205
Published: 2008
Journal Articles

Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia

Athina Giannoudis, Andrea Davies, Claire M. Lucas, Robert J. Harris, Munir Pirmohamed, Richard E. Clark
Journal: Blood
Blood (2008) 112 (8): 3348–3354.
https://doi.org/10.1182/blood-2007-10-116236
Published: 2008
Journal Articles

Characterisation of Nilotinib Transport in Chronic Myeloid Leukaemia Cells.

Andrea Davies, PhD, Athina Giannoudis, PhD, Claire M. Lucas, BSc, Robert J. Harris, PhD, Paul W. Manley, PhD, Munir Pirmohamed, PhD, FRCP, FRCP(E), Richard E. Clark, MA, MD, FRCP, FRCPat
Journal: Blood
Blood (2007) 110 (11): 2364.
https://doi.org/10.1182/blood.V110.11.2364.2364
Published: 2007
Journal Articles

Unlike Imatinib, Dasatinib Uptake into Chronic Myeloid Leukaemia Cells Is Independent of hOCT1 Expression.

Athina Giannoudis, PhD, Andrea Davies, PhD, Claire M. Lucas, BSc, Robert J. Harris, PhD, Munir Pirmohamed, PhD, FRCP, FRCP(E), Richard E. Clark, MA, MD, FRCP, FRCPat
Journal: Blood
Blood (2007) 110 (11): 3458.
https://doi.org/10.1182/blood.V110.11.3458.3458
Published: 2007
Journal Articles

Clinical and Functional Evidence That Drug Transporter Expression Dictates the Response to Imatinib in Chronic Myeloid Leukaemia.

Lihui Wang, MD, Athina Giannoudis, PhD, Steven Lane, PhD, Paula R. Williamson, PhD, Munir Pirmohamed, PhD, Richard E. Clark, MD
Journal: Blood
Blood (2006) 108 (11): 2145.
https://doi.org/10.1182/blood.V108.11.2145.2145
Published: 2006
Journal Articles

Mechanisms regulating the recruitment of macrophages into hypoxic areas of tumors and other ischemic tissues

Craig Murdoch, Athina Giannoudis, Claire E. Lewis
Journal: Blood
Blood (2004) 104 (8): 2224–2234.
https://doi.org/10.1182/blood-2004-03-1109
Published: 2004