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Journal Articles

An open-label, single-arm phase 2 trial of valemetostat for relapsed or refractory adult T-cell leukemia/lymphoma

Blood (2023) 141 (10): 1159–1168.

https://doi.org/10.1182/blood.2022016862

Published: 2023

Includes: Supplemental data

Journal Articles

Clinical Features, Treatment Patterns, and Outcomes Among 837 Patients with Adult T-Cell Leukemia-Lymphoma in the Real-World Setting: A Comparison of Endemic Regions

Bryan Valcarcel, Haruhiko Sano, Hiroo Katsuya, Atae Utsunomiya, Maki Otsuka, Masaharu Miyahara, Yasushi Takamatsu, Kenji Ishitsuka, Shinya Kimura, Junji Suzumiya, Kazuo Tamura, Daniel J Enriquez, Denisse Castro, Brady E Beltran, Henry Idrobo, Camila Peña, Lorena Fiad, Juan Carlos Ramos, Luis Enrique Malpica Castillo

Blood (2022) 140 (Supplement 1): 1072–1073.

https://doi.org/10.1182/blood-2022-168334

Published: 2022

Journal Articles

Progression of Disease within 5 Months of Adult T-Cell Leukemia-Lymphoma (ATL5) As a Clinical Endpoint for High-Risk Mortality Outcomes in the Real-World Setting: A Multinational Cohort Analysis

Blood (2022) 140 (Supplement 1): 6664–6665.

https://doi.org/10.1182/blood-2022-168101

Published: 2022

Journal Articles

Whole-genome landscape of adult T-cell leukemia/lymphoma

Blood (2022) 139 (7): 967–982.

https://doi.org/10.1182/blood.2021013568

Published: 2022

Includes: Supplemental data

Journal Articles

Pivotal Phase 2 Study of the EZH1 and EZH2 Inhibitor Valemetostat Tosylate (DS-3201b) in Patients with Relapsed or Refractory Adult T-Cell Leukemia/Lymphoma

Blood (2021) 138 (Supplement 1): 303.

https://doi.org/10.1182/blood-2021-146657

Published: 2021

Journal Articles

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

Blood (2020) 136 (Supplement 1): 29–30.

https://doi.org/10.1182/blood-2020-134360

Published: 2020

Journal Articles

First-in-Human Study of the EZH1/2 Dual Inhibitor Valemetostat in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) - Updated Results Focusing on Adult T-Cell Leukemia-Lymphoma (ATL)

Satoko Morishima, MD PhD, Kenji Ishitsuka, MD PhD, Koji Izutsu, MD PhD, Shigeru Kusumoto, MD PhD, Junya Makiyama, MD PhD, Atae Utsunomiya, MD, Kisato Nosaka, MD PhD, Takashi Ishida, MD PhD, Yoshitaka Imaizumi, MD PhD, Nobuhiko Yamauchi, MD, Kazushi Araki, DVM, PhD, Nobuaki Adachi, PhD, Tomonari Yamashita, Ryo Atsumi, PhD, Kunihiro Tsukasaki, MD PhD, Kensei Tobinai, MD PhD

Blood (2019) 134 (Supplement_1): 4025.

https://doi.org/10.1182/blood-2019-125507

Published: 2019

Journal Articles

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Hiroo Katsuya, MD, Paola Miyazato, PhD, Saiful Islam, Benjy Jek Yang Tan, MD, Yuki Inada, Misaki Matsuo, Takaharu Ueno, Masahito Tokunaga, MD PhD, Hiroyuki Hata, MD PhD, Makoto Yamagishi, PhD, Jun-Ichi Fujisawa, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD, Atae Utsunomiya, MD, Shinya Kimura, MD PhD, Yorifumi Satou, MD PhD

Blood (2019) 134 (Supplement_1): 2779.

https://doi.org/10.1182/blood-2019-124361

Published: 2019

Journal Articles

Cord Blood Transplantation with Non-TBI-RIC Regimen Using Fludarabine and Melphalan for Adult T-Cell Leukemia / Lymphoma

Nobuaki Nakano, MD, Atae Utsunomiya, MD, Ayumu Kubota, MD, Masahito Tokunaga, MD PhD, Takayoshi Miyazono, MD PhD, Tomohisa Tabuchi, MD, Jun Odawara, MD PhD, Yoshikiyo Ito, MD PhD, Shogo Takeuchi, MD, Yoshifusa Takatsuka, MD

Blood (2019) 134 (Supplement_1): 1975.

https://doi.org/10.1182/blood-2019-126463

Published: 2019

Journal Articles

TET2 Mutation Associated with Organ Infiltrations in ATLL

Takuro Kameda, MD, Kotaro Shide, MD PhD, Ayako Kamiunten, MD, Yuki Tahira, MD, Keiichi Akizuki, MD, Masaaki Sekine, MD, Tomonori Hidaka, MD, Yoko Kubuki, MD PhD, Michihiro Hidaka, MD PhD, Atae Utsunomiya, MD PhD, Takayuki Ohshima, Keisuke Kataoka, MD PhD, Seishi Ogawa, MD PhD, Kazuya Shimoda, MD PhD

Blood (2018) 132 (Supplement 1): 1345.

https://doi.org/10.1182/blood-2018-99-118065

Published: 2018

Journal Articles

Impact of Pretransplant HTLV-1 Seropositivity on Hematopoietic Stem Cell Transplantation for the Diseases Other Than ATLL- an Analysis on Behalf of JSHCT Complication Working Group-

Nobuaki Nakano, MD, Hideki Nakasone, MD PhD, Shigeo Fuji, MD PhD, Akihito Shinohara, MD PhD, Ritsuro Suzuki, MD PhD, Atae Utsunomiya, MD PhD, Tetsuya Eto, MD PhD, Yasushi Sawayama, MD, PhD, Sawako Nakachi, MD PhD, Naoyuki Uchida, MD PhD, Takahiro Fukuda, MD PhD, Junya Kanda, MD, Yoshiko Atsuta, MD PhD, Masao Ogata, MD PhD

Blood (2018) 132 (Supplement 1): 4641.

https://doi.org/10.1182/blood-2018-99-114111

Published: 2018

Journal Articles

CCR4 mutations associated with superior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment

Yuma Sakamoto, Takashi Ishida, Ayako Masaki, Takayuki Murase, Kentaro Yonekura, Yukie Tashiro, Masahito Tokunaga, Atae Utsunomiya, Asahi Ito, Shigeru Kusumoto, Shinsuke Iida, Ryuzo Ueda, Hiroshi Inagaki

Blood (2018) 132 (7): 758–761.

https://doi.org/10.1182/blood-2018-02-835991

Published: 2018

Includes: Supplemental data

Journal Articles

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

Blood (2018) 131 (2): 215–225.

https://doi.org/10.1182/blood-2017-01-761874

Published: 2018

Includes: Supplemental data

Journal Articles

EZH1/2, SWI/SNF, and MLL2 Dependent Heterochromatin Formation and Abnormal Transcriptome in Hematological Malignancies

Makoto Yamagishi, PhD, Dai Fujikawa, PhD, Makoto Hori, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Seiichiro Kobayashi, MD, PhD, Masako Iwanaga, MD PhD MPH, Atae Utsunomiya, MD, Seiji Okada, MD, PhD, Kunihiro Tsukasaki, MD PhD, Kensei Tobinai, MD PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD

Blood (2017) 130 (Supplement 1): 1200.

https://doi.org/10.1182/blood.V130.Suppl_1.1200.1200

Published: 2017

Journal Articles

First-in-Human Study of the EZH1/2 Dual Inhibitor DS-3201b in Patients with Relapsed or Refractory Non-Hodgkin Lymphomas — Preliminary Results

Dai Maruyama, MD PhD, Kensei Tobinai, MD PhD, Shinichi Makita, MD, PhD, Takashi Ishida, MD PhD, Shigeru Kusumoto, MD, Kenji Ishitsuka, MD PhD, Makoto Yoshimitsu, MD PhD, Yoshitaka Imaizumi, MD PhD, Yasushi Sawayama, MD, PhD, Shogo Takeuchi, MD, Atae Utsunomiya, MD, PhD, Kunihiro Tsukasaki, MD PhD, Sumiaki Fujitani, MSc, Kazushi Araki, D.V.M., PhD

Blood (2017) 130 (Supplement 1): 4070.

https://doi.org/10.1182/blood.V130.Suppl_1.4070.4070

Published: 2017

Journal Articles

Highly Sensitive Viral RNA-Seq Is a Powerful Tool to Analyze the Viral Transcripts in HTLV-1-Infected Individuals

Yuki Inada, Hiroo Katsuya, MD, Paola Miyazato, PhD, Benjy Jek Yang Tan, MD, Saori Iwase, Misaki Kakoki, Misaki Matsuo, Saiful Islam, Masahito Tokunaga, MD, Hiroyuki Hata, MDPhD, Yoshihisa Yamano, MD, Atae Utsunomiya, MD, Yorifumi Satou, MD PhD

Blood (2017) 130 (Supplement 1): 2484.

https://doi.org/10.1182/blood.V130.Suppl_1.2484.2484

Published: 2017

Journal Articles

Prognostic index for chronic- and smoldering-type adult T-cell leukemia-lymphoma

Hiroo Katsuya, Mototsugu Shimokawa, Kenji Ishitsuka, Kazuhiro Kawai, Masahiro Amano, Atae Utsunomiya, Ryosuke Hino, Shuichi Hanada, Tatsuro Jo, Kunihiro Tsukasaki, Yukiyoshi Moriuchi, Eisaburo Sueoka, Shinichiro Yoshida, Hitoshi Suzushima, Masaharu Miyahara, Kiyoshi Yamashita, Tetsuya Eto, Junji Suzumiya, Kazuo Tamura

Blood (2017) 130 (1): 39–47.

https://doi.org/10.1182/blood-2017-01-757542

Published: 2017

Includes: Supplemental data

Journal Articles

Impact of Chromosomal Abnormalities in Acute and Lymphoma Types Adult T-Cell Leukemia-Lymphoma

Blood (2016) 128 (22): 4123.

https://doi.org/10.1182/blood.V128.22.4123.4123

Published: 2016

Journal Articles

Treatment and Prognosis in Patients with Adult T-Cell Leukemia-Lymphoma (ATL): A Nationwide Survey in Japan

Yoshitaka Imaizumi, MD, PhD, Masako Iwanaga, MD, PhD, Kisato Nosaka, MD, PhD, Shigeki Ito, MD, PhD, Kenji Ishitsuka, MD, PhD, Atae Utsunomiya, MD, PhD, Yoshiki Tokura, MD, PhD, Takeaki Tomoyose, MD, PhD, Kazuya Shimoda, MD, PhD, Kensei Tobinai, MD, PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD, PhD, Kunihiro Tsukasaki, MD

Blood (2016) 128 (22): 5936.

https://doi.org/10.1182/blood.V128.22.5936.5936

Published: 2016

Journal Articles

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

Makoto Yamagishi, PhD, Makoto Hori, Dai Fujikawa, PhD, Daisuke Honma, PhD, Nobuaki Adachi, PhD, Takeo Ohsugi, D.V.M., PhD, Kazumi Nakano, PhD, Makoto Nakashima, Seiichiro Kobayashi, MD, PhD, Masako Iwanaga, MD, PhD, Atae Utsunomiya, MD, PhD, Seiji Okada, MD, PhD, Kunihiro Tsukasaki, MD, Kensei Tobinai, MD, PhD, Kazushi Araki, D.V.M., PhD, Toshiki Watanabe, MD, PhD, Kaoru Uchimaru, MD PhD

Blood (2016) 128 (22): 462.

https://doi.org/10.1182/blood.V128.22.462.462

Published: 2016

NARROW

An open-label, single-arm phase 2 trial of valemetostat for relapsed or refractory adult T-cell leukemia/lymphoma

Clinical Features, Treatment Patterns, and Outcomes Among 837 Patients with Adult T-Cell Leukemia-Lymphoma in the Real-World Setting: A Comparison of Endemic Regions

Progression of Disease within 5 Months of Adult T-Cell Leukemia-Lymphoma (ATL5) As a Clinical Endpoint for High-Risk Mortality Outcomes in the Real-World Setting: A Multinational Cohort Analysis

Whole-genome landscape of adult T-cell leukemia/lymphoma

Pivotal Phase 2 Study of the EZH1 and EZH2 Inhibitor Valemetostat Tosylate (DS-3201b) in Patients with Relapsed or Refractory Adult T-Cell Leukemia/Lymphoma

Whole-Genome Analysis of Adult T-Cell Leukemia/Lymphoma

First-in-Human Study of the EZH1/2 Dual Inhibitor Valemetostat in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) - Updated Results Focusing on Adult T-Cell Leukemia-Lymphoma (ATL)

The Presence and Possible Role of Virus-Host Chimeric Transcripts in Adult T-Cell Leukemia-Lymphoma

Cord Blood Transplantation with Non-TBI-RIC Regimen Using Fludarabine and Melphalan for Adult T-Cell Leukemia / Lymphoma

TET2 Mutation Associated with Organ Infiltrations in ATLL

Impact of Pretransplant HTLV-1 Seropositivity on Hematopoietic Stem Cell Transplantation for the Diseases Other Than ATLL- an Analysis on Behalf of JSHCT Complication Working Group-

CCR4 mutations associated with superior outcome of adult T-cell leukemia/lymphoma under mogamulizumab treatment

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

EZH1/2, SWI/SNF, and MLL2 Dependent Heterochromatin Formation and Abnormal Transcriptome in Hematological Malignancies

First-in-Human Study of the EZH1/2 Dual Inhibitor DS-3201b in Patients with Relapsed or Refractory Non-Hodgkin Lymphomas — Preliminary Results

Highly Sensitive Viral RNA-Seq Is a Powerful Tool to Analyze the Viral Transcripts in HTLV-1-Infected Individuals

Prognostic index for chronic- and smoldering-type adult T-cell leukemia-lymphoma

Impact of Chromosomal Abnormalities in Acute and Lymphoma Types Adult T-Cell Leukemia-Lymphoma

Treatment and Prognosis in Patients with Adult T-Cell Leukemia-Lymphoma (ATL): A Nationwide Survey in Japan

Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas

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