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Ashley A. Basiorka
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Journal Articles

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

Ashley A. Basiorka, Kathy L. McGraw, Erika A. Eksioglu, Xianghong Chen, Joseph Johnson, Ling Zhang, Qing Zhang, Brittany A. Irvine, Thomas Cluzeau, David A. Sallman, Eric Padron, Rami Komrokji, Lubomir Sokol, Rebecca C. Coll, Avril A. B. Robertson, Matthew A. Cooper, John L. Cleveland, Luke A. O’Neill, Sheng Wei, Alan F. List
Journal: Blood
Blood (2016) 128 (25): 2960–2975.
https://doi.org/10.1182/blood-2016-07-730556
Published: 2016
Includes: Supplemental data
Journal Articles

NLRP3 Inflammasome-Derived ASC Specks Are a Diagnostic Biomarker for Myelodysplastic Syndromes (MDS)

Ashley A Basiorka, Zhenjun Ma, PhD, Kathy L Mcgraw, PhD, David Sallman, MD, Brittany A Irvine, Najla H Al Ali, Eric Padron, MD, Javier Pinilla-Ibarz, MD PhD, Rami S. Komrokji, MD, Lubomir Sokol, Sheng Wei, Alan F List, MD
Journal: Blood
Blood (2016) 128 (22): 2005.
https://doi.org/10.1182/blood.V128.22.2005.2005
Published: 2016
Journal Articles

The Proinflammatory Protein S100A9 Suppresses Erythropoietin Elaboration in Patients with Myelodysplastic Syndromes

Thomas Cluzeau, MDPhD, Kathy L McGraw, PhD, Brittany Irvine, Erico Masala, Lionel Ades, MD PhD, Ashley A Basiorka, Ghulam J Mufti, FRCP, FRCPath, Jaroslaw P. Maciejewski, MD PhD, Sheng Wei, MD, Pierre Fenaux, MD PhD, Valeria Santini, MD, Alan F. List, MD
Journal: Blood
Blood (2015) 126 (23): 355.
https://doi.org/10.1182/blood.V126.23.355.355
Published: 2015
Journal Articles

Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors

Kathy L McGraw, PhD, Ashley A Basiorka, Joseph Johnson, Justine Clark, Gisela Caceres, Eric Padron, MD, Ruth Heaton, Yukiyasu Ozawa, MD PhD, Sheng Wei, MD, Lubomir Sokol, MD PhD, Alan F List, MD
Journal: Blood
Blood (2014) 124 (21): 4623.
https://doi.org/10.1182/blood.V124.21.4623.4623
Published: 2014
Journal Articles

Novel Therapeutic Approach to Improve Hematopoiesis By Targeting Myeloid Derived Suppressor Cells with a Humanized Anti-CD33 Antibody

Erika A Eksioglu, PhD, Karl-Heinz Heider, PhD, Bjoern Rueter, MD, Alexis Burnette, Max Wei, Kathy McGraw, Ashley A Basiorka, Parthik Patel, Jeffrey Lancet, Rami Komrokji, MD, Alan F. List, MD, Sheng Wei, MD
Journal: Blood
Blood (2014) 124 (21): 4597.
https://doi.org/10.1182/blood.V124.21.4597.4597
Published: 2014
Journal Articles

Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS

Ganesan Keerthivasan, Yang Mei, Baobing Zhao, Ling Zhang, Chad E. Harris, Juehua Gao, Ashley A. Basiorka, Matthew J. Schipma, James McElherne, Jing Yang, Amit K. Verma, Andrea Pellagatti, Jacqueline Boultwood, Alan F. List, David A. Williams, Peng Ji
Journal: Blood
Blood (2014) 124 (5): 780–790.
https://doi.org/10.1182/blood-2014-01-552463
Published: 2014
Includes: Supplemental data
Journal Articles

Aberrant Overexpression Of CD14 In Granulocytes Sensitizes Innate Immune Response In mDia1 Heterozygous Myelodysplastic Syndromes

Ganesan Keerthivasan, MBBS, MD, Baobing Zhao, PhD, Chad E Harris, Ling Zhang, MD, Juehua Gao, M.D., Ph.D., James McElherne, Jing Yang, Ashley A Basiorka, Matthew Schipma, Jacqueline Boultwood, Amit Verma, Alan List, MD, David A. Williams, MD, Peng Ji, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 1557.
https://doi.org/10.1182/blood.V122.21.1557.1557
Published: 2013
Journal Articles

Association of MDM2 G ene Polymorphisms SNP285 and 309 with Myelodysplastic Syndromes (MDS) Susceptibility and Outcome.

Kathy L. McGraw, Lan Min Zhang, MD, William Fulp, Hui-Yi Lin, Andres Jerez, MD, PhD, Ashley A. Basiorka, Gisela Caceres, Dana E Rollison, PhD, Debbie Billingsley, RN-BSN, Sandra E. Kurtin, RN, MS, ANP, Lubomir Sokol, MD, Ph.D, P.K. Epling-Burnette, PhD, Mar Mallo, Francesc Sole, Maria Jose Calasanz, Jose Cervera, MD, Esperanza Such, Teresa Gonzalez, Jaroslaw P. Maciejewski, MD, PhD, Alan F. List, MD
Journal: Blood
Blood (2012) 120 (21): 2823.
https://doi.org/10.1182/blood.V120.21.2823.2823
Published: 2012
Journal Articles

Lenalidomide Upregulates Erythropoietin Receptor Expression Through Inhibition of the E3-Ubiquitin Ligase Ring Finger Protein 41 (RNF41)

Ashley A. Basiorka, Kathy L. McGraw, Lori N. Griner, Ling Zhang, MD, Leentje De Ceuninck, Gisela Caceres, Lubomir Sokol, MD, Ph.D, Rami S. Komrokji, MD, Sheng Wei, MD, Jan Tavernier, Ph.D., Alan F. List, MD
Journal: Blood
Blood (2012) 120 (21): 3455.
https://doi.org/10.1182/blood.V120.21.3455.3455
Published: 2012
Journal Articles

Targeted Repression of TP53 Promotes Erythropoiesis in Del(5q) MDS and Overcomes Clinical Resistance to Lenalidomide

Gisela Caceres, Joe Johnson, Kathy L. McGraw, Ashley A. Basiorka, Kenian Liu, Ph.D., Larry J Smith, Ph.D., F. Joseph Daugherty, MD, Sheng Wei, MD, Rami S. Komrokji, MD, Ling Zhang, MD, Neil Littleton, MD, Richard A. Wells, MD, DPhil, Lubomir Sokol, MD, Ph.D, Alan F List, MD
Journal: Blood
Blood (2012) 120 (21): 920.
https://doi.org/10.1182/blood.V120.21.920.920
Published: 2012
Journal Articles

Lenalidomide Upregulates Erythropoietin Receptor Expression in Hematopoietic Progenitors by Modulating Receptor Turnover

Ashley A Basiorka, Kathy McGraw, Justine Clark, MS, Gisela Caceres, Ph.D., Joe Johnson, Laura Hall, Lubomir Sokol, MD, PhD, Sheng Wei, MD, Alan F. List, MD
Journal: Blood
Blood (2011) 118 (21): 2382.
https://doi.org/10.1182/blood.V118.21.2382.2382
Published: 2011