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Ash A. Alizadeh
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Journal Articles

Integrative genomic analysis of DLBCL identifies immune environments associated with bispecific antibody response

Open Access
Sravya Tumuluru, James K. Godfrey, Alan Cooper, Jovian Yu, Xiufen Chen, Brendan W. MacNabb, Girish Venkataraman, Yuanyuan Zha, Benedikt Pelzer, Joo Song, Gerben Duns, Brian J. Sworder, Sandeep Raj, Christopher Bolen, Elicia Penuel, Ekaterina Postovalova, Nikita Kotlov, Aleksander Bagaev, Nathan Fowler, Roni Shouval, Sonali M. Smith, Ash A. Alizadeh, Christian Steidl, Justin Kline
Journal: Blood
Blood (2025) 145 (21): 2460–2472.
https://doi.org/10.1182/blood.2024025355
Published: 2025
Includes: Supplemental data
Journal Articles

Dynamics of Circulating Tumor DNA As a Predictor of Outcomes with Lisocabtagene Maraleucel in Relapsed or Refractory Large B-Cell Lymphoma from the Transcend NHL-001 Study

Free
Dasom Lee, Brian J. Sworder, Lara Stepan, Abood Okal, Chang-Pin Huang, Xiaoman Kang, James Hamilton, Charles Macaulay, Mari Olsen, Chih Long Liu, Maximilian Diehn, Leanne Peiser, David Kurtz, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 3410.
https://doi.org/10.1182/blood-2024-200924
Published: 2024
Journal Articles

Guiding Treatment and Clinical Management of Patients with CNS Lymphomas By Minimal-Invasive Detection of Circulating Tumor DNA in Cerebrospinal Fluid

Free
Samuel Weinschenk, Ulrike Philipp, Julia C. Kuehn, Katharina J. Müller, Josia Fauser, David Böckle, Inga Gebhard, Marta Hinz, Nicolas N. Neidert, Sabine Bleul, Eliza M. Lauer, Jurik A. Mutter, Stefan K. Alig, David Kurtz, Jürgen Finke, Reinhard Marks, Maximilian Diehn, Ash A. Alizadeh, Peter C. Reinacher, Julius Wehrle, Dominik Wolf, Florian Kocher, Björn Chapuy, Jürgen Beck, Marco Prinz, Louisa von Baumgarten, Elisabeth Schorb, Justus Duyster, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 1583.
https://doi.org/10.1182/blood-2024-202943
Published: 2024
Journal Articles

Single Institution Analysis of Lymphoma Treatment Related Post-CAR Myeloid Neoplasms

Free
Mark Hamilton, Nick Phillips, Dasom Lee, Zachary Ehlinger, Anne Marijn Kramer, Hrishikesh Srinagesh, Zinaida Good, Xiaoman Kang, Mari Olsen, Chih Long Liu, Feng Tian, Brian J. Sworder, Hitomi Hosoya, Joseph G. Schroers-Martin, Sushma Bharadwaj, Sally Arai, Laura Johnston, Robert Lowsky, Everett H. Meyer, Robert S. Negrin, Andrew R. Rezvani, Judith Shizuru, Lekha Mikkilineni, Parveen Shiraz, Surbhi Sidana, Wen-Kai Weng, Vanessa E. Kennedy, Melody Smith, Lori Muffly, David Kurtz, Saurabh Dahiya, Matthew J. Frank, Crystal L. Mackall, Bita Sahaf, David B. Miklos, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 96.
https://doi.org/10.1182/blood-2024-205378
Published: 2024
Journal Articles

Circulating Tumor DNA (ctDNA) As an Early Outcome Predictor in Patients (pts) with Second-Line (2L) Large B-Cell Lymphoma (LBCL) after Lisocabtagene Maraleucel (liso-cel) Versus Standard of Care (SOC) Treatment (tx) from the Phase 3, Randomized Transform Study

Free
Lara Stepan, Sahar Ansari, Abood Okal, Justine Dell'Aringa, Ethan G. Thompson, Alessandro Crotta, Victor A. Chow, Jeremy S. Abramson, Manali Kamdar, Scott R. Solomon, Patrick B. Johnston, Bertram Glass, Pim Mutsaers, Jon E. Arnason, Stephan Mielke, Mazyar Shadman, Francisco Hernandez-Ilizaliturri, Koji Izutsu, Veronika Bachanova, Sami Ibrahimi, Jacob Chabon, David Kurtz, Ash A. Alizadeh, Leanne Peiser
Journal: Blood
Blood (2024) 144 (Supplement 1): 72.
https://doi.org/10.1182/blood-2024-199813
Published: 2024
Journal Articles

Baseline Prognostic Factors Do Not Predict End of Treatment Ctdna MRD Status and Have Limited Impact on MRD Prognostic Performance in DLBCL

Free
Jordan S Goldstein, Mark Roschewski, Won-Seog Kim, Sang Eun Yoon, Seok Jin Kim, Jason R. Westin, Ryan C Lynch, Stefan K. Alig, Sandra Close, Jacob Chabon, Davide Rossi, Wyndham H. Wilson, David Kurtz, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 651.
https://doi.org/10.1182/blood-2024-211068
Published: 2024
Journal Articles

Non-Invasive Characterization and Early Detection of Post-Transplant Lymphoproliferative Disorders

Free
Joseph G. Schroers-Martin, Andrea Garofalo, Shuyu Shi, Joanne Soo, Helen Luikart, Brian J. Sworder, Jan Boegeholz, Xiaoman Kang, Mari Olsen, Chih Long Liu, Feng Tian, Annette Skoda, Gerardo Gamino, Dave Jimil Morales, Kathrin Freystaetter, Sean Agbor-Enoh, Martin Andreas, Dan Chambers, Maria Crespo-Leiro, Gundeep Dhillon, Maryjane Farr, Seth Hollander, Abdallah Kfoury, Evan Kransdorf, Marcel Nijland, Jayant Raikhelkar, David Rosenthal, Heather Ross, Stijn Verleden, Lorenzo Zaffiri, Andreas Zuckermann, David Kurtz, Yasodha Natkunam, Maximilian Diehn, Kiran Khush, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 648.
https://doi.org/10.1182/blood-2024-206532
Published: 2024
Journal Articles

Modulation of the Tumor Microenvironment By CCL19 in Primary CNS Lymphomas

Free
Julia C. Kuehn, Roman Sankowski, Nicolas N. Neidert, Elena Grabis, Jurik A. Mutter, Stefan K. Alig, Junyi Zhang, Christian Klingler, Lavanya Ranganathan, Fabian Hummel, Sabine Bleul, Eliza M. Lauer, Dieter Henrik Heiland, Marco Prinz, Katharina J. Müller, Louisa von Baumgarten, Justus Duyster, Elisabeth Schorb, Maximilian Diehn, Ash A. Alizadeh, Peter C. Reinacher, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 856.
https://doi.org/10.1182/blood-2024-199257
Published: 2024
Journal Articles

Resolving the Microarchitecture of Classic and Transformed Follicular Lymphoma By Single Cell Alignment to Spatial Transcriptomes

Free
Troy Noordenbos, Joseph G. Schroers-Martin, Mark P. Hamilton, Soyeong Jun, Takeshi Sugio, Brian J. Sworder, Chloé Beate Steen, Mari Olsen, Chih Long Liu, Aaron Newman, Brooke Howitt, Yasodha Natkunam, David B. Miklos, Maximilian Diehn, Matthew J. Frank, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2993.
https://doi.org/10.1182/blood-2024-199300
Published: 2024
Journal Articles

The Clinical Impact and Cost-Effectiveness of PET-Based and Ctdna-Based Evaluation at End-of-Therapy after Frontline Treatment of DLBCL

Free
Swetha Kambhampati, Jordan S Goldstein, Seth Buller, Mark Roschewski, Ash A. Alizadeh, Nikhil Thiruvengadam
Journal: Blood
Blood (2024) 144 (Supplement 1): 2276.
https://doi.org/10.1182/blood-2024-203873
Published: 2024
Journal Articles

Integrating Genomic & Transcriptomic Features for Noninvasive Detection, Characterization, and Monitoring of T-Cell Lymphomas

Free
Takeshi Sugio, Monica Nesselbush, Navika Shukla, Andrea Garofalo, Jurik A. Mutter, Mohammad Shahrokh Esfahani, Stefan K. Alig, Shuyu Shi, Troy Noordenbos, Mark P. Hamilton, Cedric Rossi, Feng Tian, Chih Long Liu, Mari Olsen, Xiaoman Kang, David A Russler-Germain, Steven Horwitz, Koji Kato, Ayumu Ito, Makoto Yamagishi, Takahiro Fukuda, Koichi Akashi, Kaoru Uchimaru, Michael S. Khodadoust, Maximilian Diehn, Neha Mehta-Shah, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 454.
https://doi.org/10.1182/blood-2024-206518
Published: 2024
Journal Articles

Distinct Molecular Aberrations of Classic Hodgkin Lymphoma in Older Adults Identified By Comprehensive Genomic Profiling

Free
Cedric Rossi, Jan Boegeholz, Jordan S Goldstein, Shuyu Shi, Shengqin Su, Benoit Tessoulin, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph G. Schroers-Martin, Chih Long Liu, Mari Olsen, Xiaoman Kang, Feng Tian, David Kurtz, Takeshi Sugio, Troy Noordenbos, Marc Andre, Luc-Matthieu Fornecker, Edith Julia, Alexandra Traverse-Glehen, Olivier Casasnovas, Michael S. Binkley, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 853.
https://doi.org/10.1182/blood-2024-201644
Published: 2024
Journal Articles

Direct Method for Estimating the Fraction of T and B/Plasma Cell-Derived DNA

Free
Takeshi Sugio, Mohammad Shahrokh Esfahani, Soyeong Jun, Brian J. Sworder, Mark P. Hamilton, Hitomi Hosoya, Mari Olsen, Xiaoman Kang, Chih Long Liu, Feng Tian, David B. Miklos, David Kurtz, Maximilian Diehn, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 2223.
https://doi.org/10.1182/blood-2024-193441
Published: 2024
Journal Articles

Acquired Immunodeficiency Landscapes Via Integrated Noninvasive Viral & Immune Profiling in HIV-Associated Lymphoproliferative Disease

Free
Shuyu Shi, Kathryn Lurain, Joseph G. Schroers-Martin, Andrea Garofalo, Jurik A. Mutter, Takeshi Sugio, Xiaoman Kang, Feng Tian, Chih Long Liu, Mari Olsen, Wyndham H. Wilson, Maximilian Diehn, Mark Roschewski, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 1157.
https://doi.org/10.1182/blood-2024-211308
Published: 2024
Journal Articles

Investigating Treatment Kinetics and Local Response during and after Bridging Radiotherapy Prior to CAR-T Cell Therapy for Lymphomas

Free
Daniella Klebaner, Natalie Park, Mallika Marar, Matthew J. Frank, Susan Hiniker, Richard T. Hoppe, Joseph G. Schroers-Martin, Ranjana H. Advani, Ash A. Alizadeh, Sushma Bharadwaj, David B. Miklos, Saurabh Dahiya, Michael S. Binkley
Journal: Blood
Blood (2024) 144 (Supplement 1): 7130.
https://doi.org/10.1182/blood-2024-200930
Published: 2024
Journal Articles

Ultrasensitive Circulating Tumor DNA MRD Status Predicts Treatment Failure & Complements PET/CT throughout Treatment for Early and Advanced Stage Classic Hodgkin Lymphoma

Free
Jan Boegeholz, Cedric Rossi, Jordan S Goldstein, Stefan K. Alig, Andrea Garofalo, Mohammad Shahrokh Esfahani, Joseph G. Schroers-Martin, Chih Long Liu, Mari Olsen, Xiaoman Kang, Feng Tian, David Kurtz, Marc Andre, Luc-Matthieu Fornecker, Olivier Casasnovas, Maximilian Diehn, Herve Ghesquieres, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 565.
https://doi.org/10.1182/blood-2024-201877
Published: 2024
Journal Articles

Anatomic Genetic Heterogeneity Is Uncovered By Concurrent Cell-Free DNA and Tissue Profiling and Predicts Treatment Resistance in Diffuse Large B-Cell Lymphoma

Free
Jordan S Goldstein, Florian Scherer, Brian J. Sworder, Maximilian Diehn, David Kurtz, Ash A. Alizadeh
Journal: Blood
Blood (2024) 144 (Supplement 1): 4357.
https://doi.org/10.1182/blood-2024-209735
Published: 2024
Journal Articles

High Rates of Undetectable MRD By Phased-Seq on Interim and End of Treatment Timepoints in Untreated Advanced Stage Chl Treated with Pembrolizumab + AVD

Free
Ryan C Lynch, Stefan K. Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Brian G. Till, Vikram Raghunathan, Yolanda D Tseng, Susan Ottemiller, Bonnie Joy, Melissa Mary Fessel, Hongyan Du, Jacquelin Vandermeer, Alyssa Kelly, Heather Rasmussen, Jenna M. Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Journal: Blood
Blood (2024) 144 (Supplement 1): 3051.
https://doi.org/10.1182/blood-2024-206512
Published: 2024
Journal Articles

The Effect of Ibrutinib on the Myeloid Cell Compartment in Central Nervous System Lymphoma Slice Cultures

Free
Julia C. Kuehn, Nicolas N. Neidert, Junyi Zhang, Jurik A Mutter, Stefan K. Alig, Christian Klingler, Fabian Hummel, Sabine Bleul, Lavanya Ranganathan, Jürgen Beck, Marco Prinz, Maximilian Diehn, Ash A. Alizadeh, Justus Duyster, Roman Sankowski, Dieter Henrik Heiland, Florian Scherer
Journal: Blood
Blood (2024) 144 (Supplement 1): 4374.
https://doi.org/10.1182/blood-2024-199125
Published: 2024
Journal Articles

Comprehensive Characterization of the Cell States and Ecosystems in Classic Hodgkin Lymphoma Using Single-Cell RNA-Seq, Digital Deconvolution, and Machine Learning

Free
Shengqin Su, Ajay Subramanian, Timothy Flerlage, Jamie E. Flerlage, Cedric Rossi, Troy Noordenbos, Joseph G. Schroers-Martin, Everett J. Moding, Richard T. Hoppe, Ranjana H. Advani, Yasodha Natkunam, Ash A. Alizadeh, Michael S. Binkley
Journal: Blood
Blood (2024) 144 (Supplement 1): 4369.
https://doi.org/10.1182/blood-2024-212013
Published: 2024