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Journal Articles

JAK2 wild-type erythrocytosis associated with sodium-glucose cotransporter 2 inhibitor therapy

Clinical Trials & Observations
Naseema Gangat, Natasha Szuber, Hassan Alkhateeb, Aref Al-Kali, Animesh Pardanani, Ayalew Tefferi
Journal: Blood
Blood (2021) 138 (26): 2886–2889.
DOI: https://doi.org/10.1182/blood.2021013996
Published: 2021
Journal Articles

Anthracycline Choices for Induction Chemotherapy Among 797 Consecutive Adult Patients with Acute Myeloid Leukemia: Daunorubicin-60 Vs Idarubicin-12 Vs Daunorubicin-90

Kebede H. Begna, Naseema Gangat, Mithun V. Shah, Hassan B. Alkhateeb, Mrinal M. Patnaik, Aref Al-Kali, Michelle A. Elliot, William J Hogan, Mark R. Litzow, C. Christopher Hook, Abhishek A. Mangaonkar, David S Viswanatha, Dong Chen, Animesh D. Pardanani, Rhett P. Ketterling, Ayalew Tefferi
Journal: Blood
Blood (2021) 138 (Supplement 1): 1267.
DOI: https://doi.org/10.1182/blood-2021-147485
Published: 2021
Journal Articles

Efficacy of Oral Decitabine/Cedazuridine (ASTX727) in the CMML Subgroup from the Ascertain Phase 3 Study

Michael R. Savona, James K McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer M. Zeidan, Aref Al-Kali, H. Joachim Deeg, Prapti Patel, Mitchell Sabloff, Mary-Margaret Keating, Kim-Hien Dao, Nancy Zhu, Nashat Gabrail, Salman Fazal, Joseph Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Richard A. Wells, Harshad Amin, Jasleen K. Randhawa, Brian Leber, Yong Hao, Harold N. Keer, Mohammad Azab, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 3682.
DOI: https://doi.org/10.1182/blood-2021-154179
Published: 2021
Journal Articles

Differential Prognostic Impact of IDH1 and IDH2 Mutations in Chronic Myelomonocytic Leukemia

Connor M. Walsh, Anthony Hunter, Terra Lasho, Christy Finke, Rami S. Komrokji, Mithun V. Shah, Ayalew Tefferi, Abhishek A. Mangaonkar, Matthew T Howard, Naseema Gangat, Aref Al-Kali, Najla Al Ali, Eric Padron, Mrinal M. Patnaik
Journal: Blood
Blood (2021) 138 (Supplement 1): 3684.
DOI: https://doi.org/10.1182/blood-2021-150786
Published: 2021
Journal Articles

Improved Clinical Outcome of Patients with Myelodysplastic Syndrome (MDS) Progressing after Hypomethylating Agent: In the Era of Novel Therapies

Ahmad Ghorab, Aref Al-Kali, Michelle A. Elliot, Mithun V. Shah, Jeanne M. Palmer, Hemant S. Murthy, Mohamed A. Kharfan-Dabaja, Mark R. Litzow, James M. Foran, Talha Badar
Journal: Blood
Blood (2021) 138 (Supplement 1): 3688.
DOI: https://doi.org/10.1182/blood-2021-150626
Published: 2021
Journal Articles

Clinical Characteristics and Prognosis of Thirty-Three Patients with Myeloid Neoplasms and DDX41 Mutation: Mayo Clinic Experience

Ahmad Nanaa, Aref Al-Kali, David S. Viswanatha, James M. Foran, Talha Badar, Lisa Z. Sproat, Rong He, Phuong L Nguyen, Dragan Jevremovic, Mohamed E Salama, Patricia Greipp, Naseema Gangat, Ayalew Tefferi, Mark R. Litzow, Abhishek A. Mangaonkar, Mithun V. Shah, Mrinal M. Patnaik, Hassan B. Alkhateeb
Journal: Blood
Blood (2021) 138 (Supplement 1): 3691.
DOI: https://doi.org/10.1182/blood-2021-144400
Published: 2021
Journal Articles

DDX41 Variant of Unknown Significance (VUS) Have Distinct Clinical and Diagnostic Features but Are Associated with Similar Prognosis and Co-Mutation Patterns As Pathogenic DDX41 : Analysis of the Mayo Clinic (MC) Myeloid Next-Generation Sequencing (NGS) Cohort

Talha Badar, Ahmad Nanaa, Rong He, Aref Al-Kali, David S. Viswanatha, Emily Godsey, Lisa Z. Sproat, Mohamed A. Kharfan-Dabaja, Mrinal M. Patnaik, Hassan B. Alkhateeb, Mark R. Litzow, James M. Foran
Journal: Blood
Blood (2021) 138 (Supplement 1): 3693.
DOI: https://doi.org/10.1182/blood-2021-145115
Published: 2021
Journal Articles

Cladribine Therapy for Advanced and Indolent Systemic Mastocytosis: Mayo Clinic Experience in 42 Consecutive Cases

Ayalew Tefferi, Jaya Kittur, Faiqa Farrukh, Kebede H. Begna, Mrinal M. Patnaik, Aref Al-Kali, Michelle A Elliott, Kaaren K. Reichard, Naseema Gangat, Animesh D. Pardanani
Journal: Blood
Blood (2021) 138 (Supplement 1): 3657.
DOI: https://doi.org/10.1182/blood-2021-151009
Published: 2021
Journal Articles

Clonal Compositions Involving Epigenetic Regulator Gene Mutations in Clonal Hematopoiesis, Clonal Cytopenias of Undetermined Significance and Chronic Myelomonocytic Leukemia

Zhuoer Xie, Gina Campestri, Terra Lasho, Christy Finke, Marissa Li, Moritz Binder, Keith Robertson, Jenna Fernandez, Meredith C. Hyun, Rami S. Komrokji, Amer M. Zeidan, Jan Philipp Bewersdorf, Joshua F. Zeidner, Catherine C. Coombs, Yazan F. Madanat, Elizabeth A. Griffiths, Catherine Lai, Michael R. Savona, Mithun V. Shah, Mark R. Litzow, Ayalew Tefferi, Abhishek A. Mangaonkar, Naseema Gangat, Aref Al-Kali, Mrinal M. Patnaik
Journal: Blood
Blood (2021) 138 (Supplement 1): 2592.
DOI: https://doi.org/10.1182/blood-2021-146849
Published: 2021
Journal Articles

Acute Myeloid Leukemia in the Context of Previous History of Cancer with or without Exposure to Chemotherapy or Radiotherapy

Kebede H. Begna, Mithun V. Shah, Naseema Gangat, Hassan B. Alkhateeb, Mrinal M. Patnaik, Aref Al-Kali, Michelle A. Elliot, William J Hogan, Mark R. Litzow, C. Christopher Hook, Abhishek A. Mangaonkar, Rong He, Dong Chen, Animesh Pardanani, Rhett P. Ketterling, Ayalew Tefferi
Journal: Blood
Blood (2021) 138 (Supplement 1): 3368.
DOI: https://doi.org/10.1182/blood-2021-145745
Published: 2021
Journal Articles

Characteristics and Clinical Outcome of Patients with Clonal Cytopenias of Undetermined Significance: A Large Retrospective Multi-Center International Study

Zhuoer Xie, Meredith C. Hyun, Rami S. Komrokji, Amer M. Zeidan, Yazan F. Madanat, Joshua F. Zeidner, Catherine C. Coombs, Elizabeth A. Griffiths, Catherine Lai, Ashwin Kishtagari, James M. Foran, Talha Badar, Cecilia Arana Yi, Pinkal Desai, Lionel Ades, Afaf Osman, Justin Taylor, H. Joachim Deeg, Andrew M. Brunner, Hetty E. Carraway, Najla Al Ali, Jan Philipp Bewersdorf, Thomas Prebet, Abhay Singh, Charlton Tsai, Namrata Chandhok, Deborah Soong, Mrinal M. Patnaik, Michael R. Savona, Aref Al-Kali
Journal: Blood
Blood (2021) 138 (Supplement 1): 2158.
DOI: https://doi.org/10.1182/blood-2021-146254
Published: 2021
Journal Articles

Therapy-Related Cytopenia of Undetermined Significance (t-CCUS) As a Precursor to Therapy-Related Myeloid Neoplasms (t-MN)

Mithun V. Shah, Abhishek A. Mangaonkar, Kebede H. Begna, Hassan B. Alkhateeb, Patricia Greipp, Dong Chen, David S. Viswanatha, Rong He, Michelle A Elliott, William J Hogan, Mark R. Litzow, Kristen McCullough, Ayalew Tefferi, Naseema Gangat, Mrinal M. Patnaik, Aref Al-Kali
Journal: Blood
Blood (2021) 138 (Supplement 1): 1096.
DOI: https://doi.org/10.1182/blood-2021-145696
Published: 2021
Journal Articles

Cardiac Events in Patients with Acute Myeloid Leukemia Treated with Venetoclax in Combination with Hypomethylating Agents

Isla M. Johnson, Evandro D. Bezerra, Faiqa Farrukh, Kristen McCullough, Aref Al-Kali, Hassan B. Alkhateeb, Kebede H. Begna, Mark R. Litzow, William J Hogan, Mithun V. Shah, Mrinal M. Patnaik, Ayalew Tefferi, Naseema Gangat
Journal: Blood
Blood (2021) 138 (Supplement 1): 219.
DOI: https://doi.org/10.1182/blood-2021-149704
Published: 2021
Journal Articles

Sabatolimab (MBG453) Combination Treatment Regimens for Patients (Pts) with Higher-Risk Myelodysplastic Syndromes (HR-MDS): The MDS Studies in the Stimulus Immuno-Myeloid Clinical Trial Program

Amer M. Zeidan, Aref Al-Kali, Uma Borate, Thomas Cluzeau, Amy E. DeZern, Jordi Esteve, Aristoteles Giagounidis, Krissy Kobata, Roger Lyons, Uwe Platzbecker, David A. Sallman, Valeria Santini, Guillermo Sanz, Mikkael A. Sekeres, Andrew H. Wei, Zhijian Xiao, Marlies Van Hoef, Claire Nourry-Boulot, Islam Sadek, Bourras-Rezki Bengoudifa, Carolin Sachs, John Sabo, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 4669.
DOI: https://doi.org/10.1182/blood-2021-145626
Published: 2021
Journal Articles

Oral Decitabine/Cedazuridine in Patients with Lower Risk Myelodysplastic Syndrome: A Longer-Term Follow-up of from the Ascertain Study

Guillermo Garcia-Manero, James K McCloskey, Elizabeth A. Griffiths, Karen Yee, Amer M. Zeidan, Aref Al-Kali, H. Joachim Deeg, Prapti Patel, Mitchell Sabloff, Mary-Margaret Keating, Kim-Hien Dao, Nancy Zhu, Nashat Y. Gabrail, Salman Fazal, Joseph Maly, Olatoyosi Odenike, Hagop Kantarjian, Amy E. DeZern, Casey L. O'Connell, Gail J. Roboz, Lambert Busque, Richard A. Wells, Harshad Amin, Jasleen K. Randhawa, Brian Leber, Yong Hao, Harold N. Keer, Mohammad Azab, Michael R. Savona
Journal: Blood
Blood (2021) 138 (Supplement 1): 66.
DOI: https://doi.org/10.1182/blood-2021-144648
Published: 2021
Journal Articles

Outcome of Therapy-Related Myeloid Neoplasms with Venetoclax-Based Therapy

Mithun V. Shah, Rakchha Chhetri, Ruchita Dholakia, Hassan B. Alkhateeb, Aref Al-Kali, Mrinal M. Patnaik, Naseema Gangat, Andrew H. Wei, Ing Soo Tiong, Kebede H. Begna, Devendra Hiwase
Journal: Blood
Blood (2021) 138 (Supplement 1): 36.
DOI: https://doi.org/10.1182/blood-2021-147049
Published: 2021
Journal Articles

Mutational Landscape of MDS Patients with HMA Failure Revealed By the Correlative Analysis from Inspire Trial

Koichi Takahashi, Anna Jonasova, Selina M. Luger, Aref Al-Kali, David Valcarcel, Erica D. Warlick, Maria Diez-Campelo, Michael K Keng, Feng Wang, Ken Furudate, Patrick S. Zbyszewski, Matthew Parris, Steven M. Fruchtman, Guillermo Garcia-Manero
Journal: Blood
Blood (2021) 138 (Supplement 1): 1517.
DOI: https://doi.org/10.1182/blood-2021-152048
Published: 2021
Journal Articles

A Population-Based Study of Chronic Myelomonocytic Leukemia in the United States from 2004-2015

Gordon Ruan, MD, Caleb J. Smith, MD, Courtney Day, William Harmsen, Abhishek A. Mangaonkar, MBBS, Hassan B. Alkhateeb, MD, Kebede H. Begna, MD, Aref Al-Kali, MD, Mark Litzow, MD, William J Hogan, MB, BCh, Naseema Gangat, MBBS, Animesh Pardanani, MBBS, PhD, Michelle A Elliott, MD, Ayalew Tefferi, MD, Ronald S. Go, MD, Mrinal M. Patnaik, MDMBBS, Mithun Vinod Shah, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 30–31.
DOI: https://doi.org/10.1182/blood-2020-136350
Published: 2020
Journal Articles

Spectrum of Hematological Malignancies in 130 Patients with Germline Predisposition Syndromes - Mayo Clinic Germline Predisposition Study

Emma Catherine Difilippo, BS, Alejandro Ferrer, PhD, Laura Schultz-Rogers, PhD, Naseema Gangat, MBBS, Shakila P Khan, MD, Aref Al-Kali, MD, Abhishek A. Mangaonkar, MBBS, Animesh Pardanani, MBBS, PhD, Michelle Elliot, MD, Mark Litzow, MD, William J Hogan, MB, BCh, Alexandra P. Wolanskyj, MD, Phuong L. Nguyen, MD, Kaaren K. Reichard, MD, Matthew T Howard, MD, Rebecca L. King, MD, Dong Chen, MD, PhD, Rong He, MD, David S. Viswanatha, MD, Terra Lasho, PhD, Rajiv K. Pruthi, M.B.B.S, Pavel Pichurin, Teresa Kruisselbrink, MS, Brendan Lanpher, MD, Mark E Wylam, MD, Jennifer L. Oliveira, MD, Dusica Babovic-Vuksanovic, MD, Horatiu Olteanu, MD PhD, Mrinal M. Patnaik, MDMBBS
Journal: Blood
Blood (2020) 136 (Supplement 1): 34–35.
DOI: https://doi.org/10.1182/blood-2020-139050
Published: 2020
Journal Articles

Gilteritinib Remains Clinically Active in Relapsed/Refractory FLT3 Mutated AML Previously Treated with FLT3 inhibitors

Yazan Numan, MD, Zaid Abdel Rahman, MD, Justin Grenet, MD, Stephanie Boisclair, MD, Jan Philipp Bewersdorf, MD, Dylan Barth, PharmD, BCPS, Amer M. Zeidan, MBBS, MHS, Musa Yilmaz, MD, Shira Dinner, MD, Yehuda E. Deutsch, MD, Olga Frankfurt, MD, Mark Litzow, MD, Aref Al-Kali, MD, James M. Foran, MD, Lisa Z. Sproat, MD, Borko Jovanovic, PhD, Naval Daver, MD, Alexander E. Perl, MD, Jessica K. Altman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 5–7.
DOI: https://doi.org/10.1182/blood-2020-137251
Published: 2020