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Journal Articles

Donor natural killer cells trigger production of β-2-microglobulin to enhance post–bone marrow transplant immunity

Blood (2022) 140 (22): 2323–2334.

DOI: https://doi.org/10.1182/blood.2021015297

Published: 2022

Includes: Supplemental data

Journal Articles

Novel Tissue-Specific Targeted Radiation Delivery Reduces GI Injury and T Cell Trafficking Attenuating Allogeneic Immune Attack to Reduce GvHD in a Murine BMT Model

Srideshikan Sargur Madabushi, Hemendra Ghimire, Ji Eun Lim, Paresh Vishwasrao, Amr M H Abdelhamid, Guy Storme, Cynthia Aristei, Loredana Ruggeri, Dörthe Schaue, Monzr M. Al Malki, Amandeep Salhotra, Antonio Pierini, Susanta Hui

Blood (2022) 140 (Supplement 1): 4467–4469.

DOI: https://doi.org/10.1182/blood-2022-170509

Published: 2022

Journal Articles

HLA-Matched Treg/Tcon Allogeneic Hematopoietic Cell Transplantation Is Safe and Ensures Remarkable Chronic GvHD/Leukemia Free Survival in High-Risk Leukemia Patients

Blood (2022) 140 (Supplement 1): 2133–2134.

DOI: https://doi.org/10.1182/blood-2022-169351

Published: 2022

Journal Articles

Acute GvHD after HLA-Haploidentical Hematopoietic Cell Transplantation with Regulatory and Conventional T Cell Immunotherapy Does Not Adversely Affect Transplantation Outcomes

Blood (2021) 138 (Supplement 1): 2885.

DOI: https://doi.org/10.1182/blood-2021-152839

Published: 2021

Journal Articles

Activation of Regulatory T Cells with IL-2 and TNF-α to Promote Homing to the Gut and to Improve Acute GvHD Prevention

Antonella Mancusi, PhD, Samanta Bonato, MD, Rachele Del Sordo, MD, Sara Piccinelli, Eni Hoxha, Tiziana Zei, Roberta Iacucci Ostini, Franca Falzetti, MD, Alessandra Carotti, MD, Loredana Ruggeri, MD, Michele Giansanti, MD, Robert S. Negrin, MD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD

Blood (2019) 134 (Supplement_1): 4447.

DOI: https://doi.org/10.1182/blood-2019-123202

Published: 2019

Journal Articles

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Sara Piccinelli, Antonella Mancusi, PhD, Eni Hoxha, Loredana Ruggeri, MD, Franca Falzetti, MD, Alessandra Carotti, MD, Adelmo Terenzi, MD, Samanta Bonato, MD, Matteo Paradiso, MD, Tiziana Zei, Roberta Iacucci Ostini, Barbara Bigerna, Brunangelo Falini, MD PhD, Mauro Di Ianni, MD PhD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD, Antonio Pierini, MD PhD

Blood (2019) 134 (Supplement_1): 1917.

DOI: https://doi.org/10.1182/blood-2019-125715

Published: 2019

Journal Articles

Adoptive Immunotherapy with Regulatory and Conventional T Cells in Haploidentical Transplantation Primes Dendritic Cells to Promote T Cell Alloreactivity in the Bone Marrow and Tolerance in the Periphery

Mauro Di Ianni, MD PhD, Raffaella Giancola, Stefano Baldoni, Francesca Ulbar, Beatrice Del Papa, Stella Santarone, Annalisa Natale, Paola Olioso, Paolo Di Bartolomeo, Tiziana Bonfini, Patrizia Accorsi, Paolo Sportoletti, Alessandra Carotti, MD, Antonio Pierini, MD PhD, Loredana Ruggeri, MD, Franca Falzetti, MD, Massimo Fabrizio Martelli, MD, Andrea Velardi, MD

Blood (2019) 134 (Supplement_1): 3224.

DOI: https://doi.org/10.1182/blood-2019-126061

Published: 2019

Journal Articles

Haploidentical Transplantation with Regulatory and Conventional T Cells Improves Outcome of Patients Affected By Acute Myeloid Leukemia with Complex Karyotype and/or Monosomy 7/Del(7q)

Blood (2018) 132 (Supplement 1): 2183.

DOI: https://doi.org/10.1182/blood-2018-99-116638

Published: 2018

Journal Articles

How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation

Blood (2018) 132 (Supplement 1): 3333.

DOI: https://doi.org/10.1182/blood-2018-99-112512

Published: 2018

Journal Articles

ANTI-CMV Immunoglobulins in Association with ANTI-CMV Drugs in Patients with Hematological Malignancies Submitted to Allogeneic STEM CELL Transplantation: A MULTI-Center Retrospective Experience

Blood (2018) 132 (Supplement 1): 3381.

DOI: https://doi.org/10.1182/blood-2018-99-110252

Published: 2018

Journal Articles

Low-Toxicity/High-Efficacy HLA Haploidentical Transplantation for Elderly/Unfit Patients with Acute Leukemia

Andrea Velardi, MD, Alessandra Carotti, MD, Franca Falzetti, MD, Adelmo Terenzi, MD, Loredana Ruggeri, MD PhD, Antonio Pierini, MD PhD, Sara Piccinelli, MD, Sara Tricarico, MD, Amico Lucia, MD, Genni Casarola, MD, Valentina Lancillotta, MD, Simonetta Saldi, MD, Mauro Di Ianni, MD PhD, Cynthia Aristei, MD PhD, Massimo Fabrizio Martelli, MD PhD

Blood (2017) 130 (Supplement 1): 4601.

DOI: https://doi.org/10.1182/blood.V130.Suppl_1.4601.4601

Published: 2017

Journal Articles

DR3 signaling modulates the function of Foxp3 + regulatory T cells and the severity of acute graft-versus-host disease

Hidekazu Nishikii, Byung-Su Kim, Yasuhisa Yokoyama, Yan Chen, Jeanette Baker, Antonio Pierini, Maite Alvarez, Melissa Mavers, Kristina Maas-Bauer, Yuqiong Pan, Shigeru Chiba, Robert S. Negrin

Blood (2016) 128 (24): 2846–2858.

DOI: https://doi.org/10.1182/blood-2016-06-723783

Published: 2016

Includes: Supplemental data

Journal Articles

Chemotherapy-Based HLA Haploidentical Transplantation with Treg/Tcon Immunotherapy in Unfit/Elderly Leukemia Patients: Powerful Gvl Effect and Insights from Animal Models

Loredana Ruggeri, Alessandra Carotti, Franca Falzetti, MD, Mauro Diianni, Antonio Pierini, MD, Maria Speranza Massei, Lucia Amico, Sara Piccinelli, Elena Urbani, Massimo Fabrizio Martelli, Andrea Velardi

Blood (2016) 128 (22): 3483.

DOI: https://doi.org/10.1182/blood.V128.22.3483.3483

Published: 2016

Journal Articles

The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models

Antonio Pierini, MD, Bettina Iliopoulou, PhD, Heshan Peiris, PhD, Magdiel Perez Cruz, PhD, Jeanette Baker, PhD, Katie Hsu, PhD, William Strober, Ping-Ping Zheng, PhD, Tom Erkers, PhD, Aaron Ring, MD PhD, Andrea Velardi, Robert S. Negrin, MD, Seung Kim, MD PhD, Everett Meyer, MD PhD

Blood (2016) 128 (22): 3355.

DOI: https://doi.org/10.1182/blood.V128.22.3355.3355

Published: 2016

Journal Articles

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

Hidekazu Nishikii, MD PhD, Kim Byung-Su, Yan Chen, MD, Jeanette Baker, PhD, Antonio Pierini, MD, Maite Alvarez, PhD, Melissa Mavers, MD, Kristina Maas-Bauer, MD, Robert S. Negrin, MD

Blood (2016) 128 (22): 2148.

DOI: https://doi.org/10.1182/blood.V128.22.2148.2148

Published: 2016

Journal Articles

Foxp3 + regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells

Hidekazu Nishikii, MD PhD, Antonio Pierini, MD, Yasuhisa Yokoyama, MD,PhD, Takaharu Kimura, MD PhD, Hye-Sook Kwon, PhD, Maite Alvarez, PhD, Jeanette Baker, PhD, Judith Shizuru, MD PhD, Joy Wu, MD PhD, Shigeru Chiba, MD, PhD, Robert S. Negrin, MD

Blood (2016) 128 (22): 431.

DOI: https://doi.org/10.1182/blood.V128.22.431.431

Published: 2016

Journal Articles

TNF-α priming enhances CD4 + FoxP3 + regulatory T-cell suppressive function in murine GVHD prevention and treatment

Antonio Pierini, William Strober, Caitlin Moffett, Jeanette Baker, Hidekazu Nishikii, Maite Alvarez, Yuqiong Pan, Dominik Schneidawind, Everett Meyer, Robert S. Negrin

Blood (2016) 128 (6): 866–871.

DOI: https://doi.org/10.1182/blood-2016-04-711275

Published: 2016

Includes: Supplemental data

Journal Articles

Expanded CD4+Foxp3+ Regulatory T Cells through DR3 Signaling Have a Distinct Immunophenotype and Abrogate the Lethal Acute-Graft and Host Disease after Allogeneic Transplantation

Hidekazu Nishikii, MD, PhD, Byung-Su Kim, MD, Yasuhisa Yokoyama, MD,PhD, Jeanette Baker, PhD, Antonio Pierini, MD, Maite Alvarez, PhD, Yuqiong Pan, MD, PhD, Yan Chen, MD, Dominik Schneidawind, MD, Shigeru Chiba, MD, PhD, Robert Negrin, MD

Blood (2015) 126 (23): 1876.

DOI: https://doi.org/10.1182/blood.V126.23.1876.1876

Published: 2015

Journal Articles

TNF-Alpha Priming Enhances CD4 + FoxP3 + Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment

Antonio Pierini, MD, Caitlin Moffett, Dominik Schneidawind, MD, Jeanette Baker, PhD, Hidekazu Nishikii, MD PhD, Yuqiong Pan, MD, PhD, Maite Alvarez, PhD, Everett Meyer, MD PhD, Robert Negrin, MD

Blood (2015) 126 (23): 1885.

DOI: https://doi.org/10.1182/blood.V126.23.1885.1885

Published: 2015

Journal Articles

Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers

Pingping Zheng, PhD, Adrianne E Vasey, Jeanette Baker, Bettina Iliopoulou, PhD, Dennis B Leveson-Gower, PhD, Antonio Pierini, Dominik Schneidawind, MD, Xiaoqing You, PhD, Katie Hsu, Robert Negrin, MD, Everett Meyer, MD PhD

Blood (2015) 126 (23): 4284.

DOI: https://doi.org/10.1182/blood.V126.23.4284.4284

Published: 2015

NARROW

Donor natural killer cells trigger production of β-2-microglobulin to enhance post–bone marrow transplant immunity

Novel Tissue-Specific Targeted Radiation Delivery Reduces GI Injury and T Cell Trafficking Attenuating Allogeneic Immune Attack to Reduce GvHD in a Murine BMT Model

HLA-Matched Treg/Tcon Allogeneic Hematopoietic Cell Transplantation Is Safe and Ensures Remarkable Chronic GvHD/Leukemia Free Survival in High-Risk Leukemia Patients

Acute GvHD after HLA-Haploidentical Hematopoietic Cell Transplantation with Regulatory and Conventional T Cell Immunotherapy Does Not Adversely Affect Transplantation Outcomes

Activation of Regulatory T Cells with IL-2 and TNF-α to Promote Homing to the Gut and to Improve Acute GvHD Prevention

Regulatory T Cell Adoptive Immunotherapy Promotes B Cell Immunity after Haploidentical Transplantation

Adoptive Immunotherapy with Regulatory and Conventional T Cells in Haploidentical Transplantation Primes Dendritic Cells to Promote T Cell Alloreactivity in the Bone Marrow and Tolerance in the Periphery

Haploidentical Transplantation with Regulatory and Conventional T Cells Improves Outcome of Patients Affected By Acute Myeloid Leukemia with Complex Karyotype and/or Monosomy 7/Del(7q)

How Adoptive Immunotherapy with Conventional T and Regulatory T Cells Exerts a Gvl Effect without GvHD, after Haploidentical Hematopoietic Transplantation

ANTI-CMV Immunoglobulins in Association with ANTI-CMV Drugs in Patients with Hematological Malignancies Submitted to Allogeneic STEM CELL Transplantation: A MULTI-Center Retrospective Experience

Low-Toxicity/High-Efficacy HLA Haploidentical Transplantation for Elderly/Unfit Patients with Acute Leukemia

DR3 signaling modulates the function of Foxp3 + regulatory T cells and the severity of acute graft-versus-host disease

Chemotherapy-Based HLA Haploidentical Transplantation with Treg/Tcon Immunotherapy in Unfit/Elderly Leukemia Patients: Powerful Gvl Effect and Insights from Animal Models

The Use of Monoclonal Antibody Directed Chimeric Antigen Receptors to Facilitate Conventional T Cell and Treg Control of GvHD and Tissue Tolerance in Murine Models

DR3 Signaling Modulates the Function of Foxp3 + regulatory T Cells and the Severity of Acute Graft and Host Disease

Foxp3 + regulatory T Cells Maintain Bone Marrow Microenvironment for B Cell Differentiation from Hematopoietic Stem Cells

TNF-α priming enhances CD4 + FoxP3 + regulatory T-cell suppressive function in murine GVHD prevention and treatment

Expanded CD4+Foxp3+ Regulatory T Cells through DR3 Signaling Have a Distinct Immunophenotype and Abrogate the Lethal Acute-Graft and Host Disease after Allogeneic Transplantation

TNF-Alpha Priming Enhances CD4 + FoxP3 + Regulatory T Cell Suppressive Function in GvHD Prevention and Treatment

Increased Activity in the T Cell Effector Phase and Enhanced T Cell Repertoire Target-Tissue Stability Distinguish Alloreactivity Across Major Versus Minor Histocompatibility Barriers

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American Society of Hematology

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American Society of Hematology

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