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Alexander Hoffmann
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Journal Articles

Population dynamics modeling reveals that myeloid bias involves both HSC differentiation and progenitor proliferation biases

Apeksha Singh, Jennifer J Chia, Dinesh S. Rao, Alexander Hoffmann
Journal: Blood
Blood blood.2024025598.
https://doi.org/10.1182/blood.2024025598
Published: 2024
Includes: Supplemental data
Journal Articles

Modeling Cell Population Dynamics in Early Hematopoiesis Reveals Mechanisms of Myeloid Bias Mediated By NFκB-Dysregulation

Apeksha Singh, Jennifer J Chia, Yu-Sheng Eason Lin, Dinesh S. Rao, Alexander Hoffmann
Journal: Blood
Blood (2023) 142 (Supplement 1): 2669.
https://doi.org/10.1182/blood-2023-187342
Published: 2023
Journal Articles

NFκB Dysregulation in the Bone Marrow Niche Drives Epigenomic Reprogramming of Hematopoietic Stem Cells and Myeloid Bias

Jennifer J Chia, Apeksha Singh, Yu-Sheng Eason Lin, Tiffany Tran, Jennifer King, Dinesh S. Rao, Alexander Hoffmann
Journal: Blood
Blood (2023) 142 (Supplement 1): 4079.
https://doi.org/10.1182/blood-2023-189801
Published: 2023
Journal Articles

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease

Verena Petzer, Piotr Tymoszuk, Malte Asshoff, Joana Carvalho, Jonathan Papworth, Cecilia Deantonio, Luke Bayliss, Matthew Stephen Wake, Markus Seifert, Natascha Brigo, Lara Valente de Souza, Richard Hilbe, Philipp Grubwieser, Egon Demetz, Stefanie Dichtl, Chiara Volani, Sylvia Berger, Felix Böhm, Alexander Hoffmann, Christa Pfeifhofer-Obermair, Laura von Raffay, Sieghart Sopper, Stephanie Arndt, Anja Bosserhoff, Léon Kautz, Prunelle Perrier, Manfred Nairz, Dominik Wolf, Guenter Weiss, Volker Germaschewski, Igor Theurl
Journal: Blood
Blood (2020) 136 (9): 1080–1090.
https://doi.org/10.1182/blood.2019004653
Published: 2020
Includes: Supplemental data
Journal Articles

B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel

Jonathan V. Almaden, Yi C. Liu, Edward Yang, Dennis C. Otero, Harry Birnbaum, Jeremy Davis-Turak, Masataka Asagiri, Michael David, Ananda W. Goldrath, Alexander Hoffmann
Journal: Blood
Blood (2016) 127 (10): 1276–1286.
https://doi.org/10.1182/blood-2014-10-606988
Published: 2016
Includes: Supplemental data
Journal Articles

The NFkB System Regulates Flt3-Mediated Hematopoiesis

Yi Liu, PhD, Alexander Hoffmann, PhD
Journal: Blood
Blood (2015) 126 (23): 3592.
https://doi.org/10.1182/blood.V126.23.3592.3592
Published: 2015
Journal Articles

Coordination between NF-κB family members p50 and p52 is essential for mediating LTβR signals in the development and organization of secondary lymphoid tissues

James C. Lo, Soumen Basak, Ethan S. James, Raechel S. Quiambo, Marcus C. Kinsella, Maria-Luisa Alegre, Falk Weih, Guido Franzoso, Alexander Hoffmann, Yang-Xin Fu
Journal: Blood
Blood (2006) 107 (3): 1048–1055.
https://doi.org/10.1182/blood-2005-06-2452
Published: 2006