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Alberto Riva
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Journal Articles

Gene Editing and Multi-Omics Reveal Novel Metabolic Vulnerabilities in t(4;14)-Associated Multiple Myeloma

Amin Sobh, Charlotte L Kaestner, Alberto Riva, Karthik Vasan, Alisha Patel, Greeshma Surapaneni, Janai Poullard, Elena Encinas, Richard Lynn Bennett, Constantine S. Mitsiades, Lawrence H. Boise, Navdeep S. Chandel, Jonathan D. Licht
Journal: Blood
Blood (2022) 140 (Supplement 1): 5911–5912.
DOI: https://doi.org/10.1182/blood-2022-169256
Published: 2022
Journal Articles

Dysregulation of Epigenetic Landscape Uncovered the Mechanisms Underlying the Relapse of Pediatric Acute Lymphoblastic Leukemia with NSD2 Mutation

Jianping Li, Priscillia Lhoumaud, Alberto Riva, Crissandra Piper, Daphne Dupere-Richer, Heidi Casellas Roman, Amin Sobh, Charlotte L Kaestner, Alok Swaroop, Marta Kulis, Richard Lynn Bennett, Jane Skok, Jonathan D. Licht
Journal: Blood
Blood (2021) 138 (Supplement 1): 3297.
DOI: https://doi.org/10.1182/blood-2021-149985
Published: 2021
Journal Articles

Dnmt3a Mutations in the Hematopoietic System Promote Colitis-Associated Colon Cancer: A Model of Clonal Hematopoiesis in Solid Tumors

Yang Feng, Rachel Newsome, Troy Robinson, Robert L. Bowman, Ashley Zuniga, Kendra Hall, Cassandra Bernsten, Daniil Shabashvili, Kathryn Krajcik, Chamara Gunaratne, Zachary Zaroogian, Kartika Venugopal, Heidi Casellas Roman, Ross L. Levine, Alberto Riva, Daniel Kopinke, Christian Jobin, Dorina Avram, Olga A Guryanova
Journal: Blood
Blood (2021) 138 (Supplement 1): 2161.
DOI: https://doi.org/10.1182/blood-2021-149740
Published: 2021
Journal Articles

Adenylate Kinase 2 Is a Selective Multiple Myeloma Cell Dependency That Is Preferentially Essential in NSD2-Overexpressing Cells

Amin Sobh, Charlotte L Kaestner, Jianping Li, Alberto Riva, Richard Lynn Bennett, Jonathan D. Licht
Journal: Blood
Blood (2021) 138 (Supplement 1): 1586.
DOI: https://doi.org/10.1182/blood-2021-153284
Published: 2021
Journal Articles

Functional CRISPR Screening Identifies Ptprg As a Driver of Migration and Adhesion in NSD2-E1099K ALL

Charlotte L Kaestner, Amin Sobh, Jianping Li, Alberto Riva, Richard Lynn Bennett, Jonathan D. Licht
Journal: Blood
Blood (2021) 138 (Supplement 1): 1149.
DOI: https://doi.org/10.1182/blood-2021-154009
Published: 2021
Journal Articles

Adenylate Kinase 2 Is a Selective Dependency in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Jianping Li, MD, Alberto Riva, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
DOI: https://doi.org/10.1182/blood-2020-141266
Published: 2020
Journal Articles

KDM6A Controls Genes Modulating Immune Surveillance in Multiple Myeloma

Daphne Dupere-Richer, PhD, Sayantan Maji, PhD, Alberto Riva, PhD, Gabrielle Quickstad, Marta Kulis, Darby Monagle, José I. Martín-Subero, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 14.
DOI: https://doi.org/10.1182/blood-2020-141285
Published: 2020
Journal Articles

NSD2-E1099K Mutation Leads to Glucocorticoid-Resistant B Cell Lymphocytic Leukemia in Mice

Jianping Li, MD, Crissandra Piper, LATG, Daphne Dupere-Richer, PhD, Heidi Casellas Roman, MS, Alok Swaroop, PhD, Catalina Troche, PhD, Jon Oyer, PhD, Christine Will, MS, Alberto Riva, PhD, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 3–4.
DOI: https://doi.org/10.1182/blood-2020-141295
Published: 2020
Journal Articles

DNMT3A with Leukemia-Associated Mutations Directs Sensitivity to DNA Damage at Replication Forks

Kartika Venugopal, MS, Daniil E Shabashvili, PhD, Jianping Li, MD, Luisa M Posada, Richard Lynn Bennett, PhD, Yang Feng, MS, Daphne Dupere Richer, PhD, Alberto Riva, PhD, Santhi Pondugula, PhD, Jonathan E. Bird, PhD, Jonathan D. Licht, MD, Olga A Guryanova, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 535.
DOI: https://doi.org/10.1182/blood-2019-128213
Published: 2019
Journal Articles

Identification of Genetic Vulnerabilities and Synthetic-Lethal Targets in NSD2-High Multiple Myeloma

Amin Sobh, PhD, Charlotte Kaestner, Alberto Riva, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3757.
DOI: https://doi.org/10.1182/blood-2019-125951
Published: 2019
Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance Via Blocking Receptor Auto-Induction and BIM/Bmf Expression in ALL

Jianping Li, MD, Catalina Troche, PhD, Julia Hlavka Zhang, BS, Jonathan Shrimp, PhD, Jacob S. Roth, PhD, Duohui Jing, PhD, Alok Swaroop, PhD, Marta Kulis, Jon Oyer, PhD, Christine Will, MS, Daphne Dupere-Richer, PhD, Alberto Riva, PhD, Crissandra Pipe, LATG, Amin Sobn, PhD, Sharon Norton, MS, Richard Lynn Bennett, PhD, Min Shen, PhD, Matthew D. Hall, PhD, Richard B. Lock, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3758.
DOI: https://doi.org/10.1182/blood-2019-126910
Published: 2019
Journal Articles

A Gain of Function Mutation in the NSD2 Histone Methyltransferase Drives Glucocorticoid Resistance of Acute Lymphoblastic Leukemia

Jianping Li, MD, Catalina Troche, PhD, Alok Swaroop, PhD, Marta Kulis, PhD, Jon Oyer, PhD, Christine Will, MS, Daphne Dupere-Richer, PhD, Alberto Riva, PhD, Crissandra Pipe, LATG, Sharon Norton, MS, Richard Lynn Bennett, PhD, Jonathan D. Licht, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 653.
DOI: https://doi.org/10.1182/blood-2018-99-116309
Published: 2018